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Dietary supplement

Blue Light Defense Formula Ingredients & Drug Interactions

by Blue Guard

Blue Light Defense Formula label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Blue Light Defense Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Blue Light Defense Formula is a dietary supplement by Blue Guard with 1 active ingredient. Its ingredients are commonly taken for digestive upset, antimicrobial and antifungal, skin and wound care.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Blue Light Defense Formula by Blue Guard

Ask about any prescription or over-the-counter medication and we check it for interactions with Blue Light Defense Formula by Blue Guard — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Blue Light Defense Formula by Blue Guard

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Lutemax 2020” is listed as a grouped ingredient — the label gives one combined amount (100 mg) without saying how much of each component you get.
  • “Zeaxanthin Isomers” is listed as a grouped ingredient — the label gives one combined amount (4 mg) without saying how much of each component you get.

Blue Guard's Blue Light Defense Formula contains 3 active ingredients: lutein, RR-zeaxanthin, and meso-zeaxanthin — plant pigments that accumulate in the eye and are thought to protect against light damage. The product also includes inactive ingredients (sunflower oil, bovine gelatin, glycerin, purified water, titanium dioxide, and FD&C Blue #1) that serve as the softgel capsule base and fillers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: eye health and blue light protection.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Dry eye, Myopia, Central serous retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD).

Lutein and both zeaxanthin forms are possibly effective for age-related macular degeneration (AMD), the most common cause of vision loss in older adults. For cataracts, lutein is possibly effective; the zeaxanthin ingredients don't have data on file for cataracts specifically.

The evidence isn't established in our data for other conditions like cognitive decline, Alzheimer disease, asthma, or breast cancer.

The evidence, ingredient by ingredient Tagetes Lutein Zeaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein is generally well tolerated at typical supplement doses — trials up to 20 mg daily have shown no adverse effects. Both zeaxanthin forms are also generally well tolerated at standard amounts.

Regarding pregnancy and lactation, all three active ingredients are rated as likely safe, though the data on concentrated supplement doses during pregnancy and breastfeeding is limited — talk with your doctor or pharmacist for personalized guidance if you're pregnant, planning pregnancy, or nursing.

Side effects, ingredient by ingredient Tagetes Lutein Zeaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antidiabetes drugs carry a Moderate interaction risk with the zeaxanthin ingredients in this formula — they may together increase the risk of low blood sugar. Check your specific diabetes medication with the tool below before you start, and let your doctor or pharmacist know.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This formula is worth considering if you're concerned about eye health and macular degeneration as you age. If you take diabetes medication, check with your doctor or pharmacist before starting — the zeaxanthin ingredients may theoretically lower blood sugar.

Similarly, run your exact medications through the checker on this page to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blue Light Defense Formula, straight from the product label.

Brand Blue Guard
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Nov 21, 2018
DSLD ID 173285
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blue Light Defense Formula by Blue Guard, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
IngredientAmount% DV
Lutein20 mg--
Lutemax 2020100 mg--
Zeaxanthin Isomers4 mg--
RR-Zeaxanthin0 NP--
Meso-Zeaxanthin0 NP--

Other ingredients: Sunflower Oil, Bovine Gelatin, Glycerin, purified Water, Titanium Dioxide, FD&C Blue #1

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Eye health What is blue light? Blue light, another name for high-energy visible (HEV) light in the blue and violet part of the light spectrum, is a particularly intense light wave emitted by many modern electronics - including computers, tablets, TV's and smart phones - and even compact fluorescent light bulbs. With today's increased use of electronic devices, the population is being exposed to more sources of blue light than ever before and for longer periods of time.

Our eyes are bombarded with daily assaults from electronic devices, therefore protecting our eyes becomes very important.

Strengthen Increases the natural density of the macular pigment, which is the protective layer in your eyes. Defend Potent Antioxidants help protect against oxidative stress to defend against the harmful effects of blue light. Filter Filters out high energy blue light stopping much of the light as it reaches your macular pigment.

Source: Omniactive Health Technology Studies. Source: www.bluelightexposed.com -The dark side of blue light.

Guards against the harmful effects of blue light New! Clinically proven! Vision and eye health Guards against the harmful effects of blue light extensive screen time Strengthen Filter Defend Promotes healthy eye function Helps reduce glare sensitvity

60 Day Supply Blue light is all around us. TV Newer televisions use LED back light technology. These LED's emit strong blue light waves. LightBulb Modern energy efficient light bulbs and Fluorescent bulbs emit a significant amount of blue light. Mobile Devices Mobile devices such as cellphones and tables also utilize LEDs' which emit blue light waves. Promotes healthy vision which is essential at any age.

Brand IP Statement(s)

How can Blue Guard help?

Blue Guard supplements with Lutemax 2020 have Lutein and Zeaxanthin isomers in a unique combination, which support our eyes by filtering high energy blue light, reducing glare sensitivity, support speed of visual processing and support contract sensitivity. Blue Guard supplements taken daily will help strengthen, filter and defend against blue light's harmful effects.

All Rights Reserved

Lutemax 2020 and Lutein for Every Age are trademarks of OmniActive Health Technologies.

Lutemax 2020 is a registered trademark of OmniActive Health Technologies Ltd.

Formula

Lutemax 2020 Lutein & Zeaxanthin With Lutein and Zeaxanthin ingredients, clinically tested for healthy vision.

Lutein For Every Age

Suggested/Recommended/Usage/Directions

1 Daily

Suggested Use: As a dietary supplement, take one softgel daily, preferably with a meal.

Formulation

No: Fish, Soy, Peanuts, Tree Nuts, Shellfish, Eggs, Milk, Wheat.

Gluten Free

Precautions

Warnings: Tamper evident seal under cap. Do not use if printed seal is broken or missing.

Pregnant or nursing women and individuals taking any medication, or who have an underlying health condition should consult with their physician before using this product.

Keep out of reach of children.

Storage

Store at 15(0) - 30 (0) C (59(0)-86(0)F)

Seals/Symbols

Made in the USA

Gluten Free

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Blue Light Defense Formula by Blue Guard label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Blue Light Defense Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Blue Light Defense Formula by Blue Guard

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Lutemax 2020

No known
interactions
100 mg per serving

Tagetes (marigold) is a group of flowering plants used in traditional medicine and as a source of plant pigments like lutein. Human evidence for most...

Lutemax 2020 monograph & interactions

Other (inactive) ingredients: Sunflower Oil, Bovine Gelatin, Glycerin, Purified Water, Titanium Dioxide, FD&C Blue #1. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blue Light Defense Formula by Blue Guard Drug Interactions

Want to check YOUR meds against Blue Light Defense Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Blue Light Defense Formula interact with 86 drugs. Click any drug to see the details.

0 of the 1 ingredient in Blue Light Defense Formula interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Blue Light Defense Formula with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Blue Light Defense Formula, from the product label.

Blue Guard

See all Blue Guard products
Name
Quest Products Inc.
City
Pleasant Prairie
State
WI
ZipCode
53158
Phone Number
800-650-0113
Web Address
BlueGuardHealth.com
Pharmacist Counseling Corner

Blue Light Defense Formula by Blue Guard: Common Questions

Does Blue Light Defense Formula by Blue Guard interact with any medications?
Yes. Based on its ingredients, Blue Light Defense Formula has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blue Light Defense Formula contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my vision or prevent age-related macular degeneration?
Lutein and zeaxanthin both show possibly effective evidence for age-related macular degeneration. That's the strongest evidence we have for these ingredients — but 'possibly effective' means the research is promising, not definitive. Talk with your eye doctor about whether this supplement fits your eye health plan.
I'm pregnant. Is it safe to take this?
All three active ingredients are rated as likely safe in pregnancy, but the data on concentrated supplement doses during pregnancy is limited. Talk with your doctor before starting — they know your situation best and can give you personalized advice.
What does lutein do?
Lutein is a plant pigment that collects in the retina of your eye, where it's thought to filter harmful blue light and protect against age-related damage. It's also possibly effective for cataracts.
What are RR-zeaxanthin and meso-zeaxanthin?
They're two forms of zeaxanthin, another plant pigment that also accumulates in the eye alongside lutein and serves a similar protective role. Both are included in this formula for that combined eye-defense effect.
I take diabetes medication. Can I take this?
The zeaxanthin in this formula may theoretically lower blood sugar when taken with diabetes drugs, raising the risk of hypoglycemia. Check your exact medication with the tool on this page, and talk with your doctor or pharmacist — they can tell you whether it's safe for you.
Are there any side effects?
At typical supplement doses, lutein and both zeaxanthin forms are generally well tolerated with no reported adverse effects. If you notice anything unusual after starting, tell your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blue Light Defense Formula is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blue Light Defense Formula label
Go deeper

The Full Monographs Behind Blue Light Defense Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tagetes

Tagetes (marigold) is a group of flowering plants used in traditional medicine and as a source of plant pigments like lutein. Human evidence for most health benefits is very limited, and the...

Read the full Tagetes monograph → Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph → Herb & supplement monograph

Zeaxanthin

Interacts with 86 drugs

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...

Read the full Zeaxanthin monograph →
Sources

Sources & How We Checked

Blue Light Defense Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Tagetes 1 reference
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.

See these in context on the Tagetes monograph →

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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