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Dietary supplement

Blueberry Extract 5,000 mg Alcohol-Free Ingredients & Drug Interactions

by Nature's Answer

Liquid Category: Botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Blueberry Extract 5,000 mg Alcohol-Free is a dietary supplement by Nature's Answer with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, heart health, brain and memory health.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Blueberry Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Blueberry Extract 5,000 mg Alcohol-Free by Nature's Answer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: blueberry extract at 5,000 mg per serving. The extract is alcohol-free and suspended in glycerin and purified water.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Blueberry product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Blueberry's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“Promotes overall health and wellbeing”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence we hold doesn't establish that blueberry extract works for most conditions tied to it. For high blood pressure, the data rates it as possibly ineffective.

For age-related cognitive decline, anxiety, athletic performance, high cholesterol (hyperlipidemia), and cardiovascular disease, there isn't enough reliable evidence in our data to make a rating.

The evidence, ingredient by ingredient Blueberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberries as whole food are widely eaten and generally well tolerated. This concentrated extract, however, hasn't been well studied in pregnancy, so the safety data advises caution.

The same applies to breastfeeding — the safety of high-dose extracts isn't known. When taken orally, blueberry extract is generally well tolerated, though a small number of trial participants reported constipation, diarrhea, nausea, or vomiting.

In one clinical trial using freeze-dried blueberries, about a quarter of patients dropped out in the first week due to gastrointestinal complaints.

Side effects, ingredient by ingredient Blueberry

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blueberry.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take antidiabetes drugs (like metformin or insulin), flurbiprofen, or buspirone before starting this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Only minor medication interactions are documented, and safety information is well characterized.

If you take antidiabetes drugs, talk to your pharmacist before adding this extract — there's a theoretical risk of low blood sugar. The same goes if you take flurbiprofen or buspirone.

The evidence for what this product actually does isn't strong in our data, so be clear on what you're hoping it'll help with.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blueberry Extract 5,000 mg Alcohol-Free, straight from the product label.

Brand Nature's Answer
Barcode (UPC) 083000005817
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 326714
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blueberry Extract 5,000 mg Alcohol-Free by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
083000005817
IngredientAmount% DV
Blueberry Extract155 mg--

Other ingredients: Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Gluten free

Promotes overall health & wellbeing

Gluten-free Alcohol-free Absolutely no preservatives

Seals/Symbols

K Parve (Kosher)

Formula

K Parve (Kosher)

Vaccinium corymbosum Made from 5,000 mg Fresh blueberries per serving

Brand IP Statement(s)

Nature's Answer Since 1972 Discover Nature's Answer

Copyright 2018 Nature's Answer

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary Supplement, take 1 mL (28 drops) in juice or water as desired. Shake well.

Precautions

Keep out of reach of children.

Warning: Do not use if pregnant or nursing.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

General Statements

"The true value of a plant lies deep within its natural holistic balance." Frank D'Amelio, Sr., Founder, Nature's Answer

For product information, call (800)439-2324

See for yourself

Blueberry Extract 5,000 mg Alcohol-Free by Nature's Answer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Blueberry Extract 5,000 mg Alcohol-Free by Nature's Answer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Blueberry Extract

Interacts with
88 drugs
155 mg per serving Form: Vaccinium corymbosum Extract

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most p...

Blueberry Extract monograph & interactions

Other (inactive) ingredients: Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blueberry Extract 5,000 mg Alcohol-Free by Nature's Answer Drug Interactions

Want to check YOUR meds against Blueberry Extract 5,000 mg Alcohol-Free?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
88Drugs
88 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Blueberry Extract 5,000 mg Alcohol-Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Blueberry Extract3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Blueberry Extract 5,000 mg Alcohol-Free, from the product label.

Nature's Answer

See all Nature's Answer products
Name
Nature's Answer
Street Address
85 Commerce Drive
City
Hauppauge
State
NY
ZipCode
11788
Phone Number
(800) 439-2324
Web Address
www.naturesanswer.com
Pharmacist Counseling Corner

Blueberry Extract 5,000 mg Alcohol-Free by Nature's Answer: Common Questions

Does Blueberry Extract 5,000 mg Alcohol-Free by Nature's Answer interact with any medications?
Yes. Based on its ingredients, Blueberry Extract 5,000 mg Alcohol-Free has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blueberry Extract 5,000 mg Alcohol-Free contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is blueberry extract safe to take while I'm pregnant or breastfeeding?
Eating blueberries as food is fine, but concentrated extracts haven't been well studied in pregnancy or while breastfeeding. Talk with your doctor or pharmacist about whether this supplement is right for you in those situations — they can weigh the pros and cons based on your health.
What are the side effects of this extract?
Most people tolerate it well. Some experience constipation, diarrhea, nausea, or vomiting — particularly if they're sensitive to concentrated forms. In one trial, a small number of participants had enough gastrointestinal trouble to quit the study early.
Will this help my blood pressure or cholesterol?
For blood pressure, the evidence we hold rates blueberry extract as possibly ineffective. For high cholesterol, there isn't enough reliable data to make a rating. If you're looking to support those conditions, talk with your doctor about what the evidence actually backs.
Can this improve my memory or brain function as I age?
There isn't enough reliable evidence in our data to say whether it helps with age-related cognitive decline. The research on this one just isn't established enough for us to rate it.
What does the 5,000 mg refer to?
That's the amount of blueberry extract in each serving. This product is liquid and alcohol-free, so it goes into the blueberry extract directly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blueberry Extract 5,000 mg Alcohol-Free is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blueberry Extract 5,000 mg Alcohol-Free label
Go deeper

The Full Monographs Behind Blueberry Extract 5,000 mg Alcohol-Free’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Blueberry Extract 5,000 mg Alcohol-Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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