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Dietary supplement

Bronchial Soothe Ingredients & Drug Interactions

by Enzymatic Therapy

Liquid Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Bronchial Soothe is a dietary supplement by Enzymatic Therapy with 1 active ingredient. Its ingredients are commonly taken for cough and chest congestion, bronchitis, asthma symptoms.Based on those ingredients, 280 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are English Ivy Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Computed from our clinical databases

HelloPharmacist Scorecard of Bronchial Soothe by Enzymatic Therapy

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

None of the active ingredients could be matched to our evidence database, so the stated purpose can't be graded.

Why this rating?
  • The label markets this product for: expectorant for respiratory catarrhs and bronchial conditions.
  • We looked for evidence on: Bronchitis, Cough, Respiratory tract infections, chest congestion, chronic bronchitis, mucus clearance.
  • We couldn't match any of the active ingredients to a HelloPharmacist monograph, so there's no evidence data to grade that purpose against.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “English Ivy Leaf Extract” is listed as a grouped ingredient — the label gives one combined amount (33 mg) without saying how much of each component you get.
Known Interaction Concern
Not assessable

None of the active ingredients could be matched to our interaction database.

Why this rating?
  • We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
Safety Information
Unable to assess

None of the active ingredients could be matched to our safety data.

Why this rating?
  • We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.

Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bronchial Soothe, straight from the product label.

Brand Enzymatic Therapy
Barcode (UPC) 763948901234
Net contents 100 mL; 3.4 fl. Oz.
Market status Off market
Date entered into DSLD Nov 25, 2014
DSLD ID 39638
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bronchial Soothe by Enzymatic Therapy, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 tsp
Maximum serving Sizes:
2 tsp
UPC/BARCODE
763948901234
IngredientAmount% DV
English Ivy Leaf Extract33 mg--
standardized to contain 9 mg of Hederacoside C9 mg--

Other ingredients: purified Water, Glycerin, Fructose, Natural flavours, Sucrose Laurate, Potassium Sorbate, Citric Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Ivy Leaf Syrup

Contra-indications: none known

Non-Drowsy Formula

~ Clinically proven respiratory support ~ Naturally supports clear bronchial passages ~ Soothes occasional irritation

IMMUNE

Breath Easy with Doctor-Recommended Bronchial Soothe.

Ivy leaf extract is a traditional ingredient that has been used for centuries to support bronchial health. Exclusive ivy extract provides natural support for optimal lung and bronchial passageway health. Unlike alcohol-based syrups, natural ingredients provide greater levels of safety. Multiple clinical studies prove that Bronchial Soothe is safe for the entire family! Clinically proven for lung and bronchial passageway health.

{chart} Ivy Extract Proven More Effective in Clinical Tests % Effective for lung health Ivy Extract Bronchial Soothe Synthetic Chemical Preparation Clinical studies show natural ivy extract is more effective in supporting lung and bronchial health as compared to products made solely with synthetic chemicals.

Storage

Recommended use or purpose: As an expectorant for catarrhs of the respiratory passages, for the symptomatic treatment of chronic inflammatory bronchial conditions.

Suggested/Recommended/Usage/Directions

Adult Dosage: 2 tsp. (10 mL) two to six times per day or as directed by your health care practitioner. Children 6 years and older: 1-1/2 tsp. (7.5 mL) 2 to 6 times per day or as directed by a health care practitioner.

For convenience, a graduated dosage cup is enclosed. May be mixed in a warm beverage.

Precautions

Risk Information: Consult a physician if symptoms do not improve within 5 days or if cough worsens, lasts more than 7 days, or is accompanied by high fever.

Keep out of reach of children.

Saftey-sealed for your protection with a breakable cap.

Seals/Symbols

LABORATORY TESTED PURITY, SAFETY & PERFORMANCE

Enzymatic Therapy What Better Feels Like

General

LBX08771CAN.01

FDA Statement of Identity

DIETARY SUPPLEMENT

Formulation

Alcohol-Free

Formula

Contains soothing natural ivy leaf.

Well tolerated in children.

See for yourself

Bronchial Soothe by Enzymatic Therapy label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Bronchial Soothe by Enzymatic Therapy

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 tsp Dosage formLiquid Amounts shown are per serving.

English Ivy Leaf Extract

Interacts with
280 drugs
33 mg per serving

English ivy leaf extract is most commonly used in cough and cold syrups to help loosen mucus and ease coughing, and it is a popular ingredient in many...

English Ivy Leaf Extract monograph & interactions
  • › Standardized to contain 9 mg of Hederacoside C

Other (inactive) ingredients: Purified Water, Glycerin, Fructose, Natural flavours, Sucrose Laurate, Potassium Sorbate, Citric Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bronchial Soothe by Enzymatic Therapy Drug Interactions

Bronchial Soothe contains a single active ingredient, and it has known interactions with 280 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Bronchial Soothe?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
280Drugs
280 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Bronchial Soothe with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

English Ivy Leaf Extract3 drug types · 280 drugs

Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, English ivy might increase the levels of drugs metabolized by CYP2C19.
In vitro research shows that English ivy inhibits CYP2C19 enzymes. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C8 (Cyp2C8) Substrates

Theoretically, English ivy might increase the levels of drugs metabolized by CYP2C8.
In vitro research shows that English ivy inhibits CYP2C8 enzymes. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, English ivy might increase the levels of drugs metabolized by CYP2D6.
In vitro research shows that English ivy inhibits CYP2D6 enzymes. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Bronchial Soothe, from the product label.

Enzymatic Therapy

Name
Enzymatic Therapy (Cananda), Inc.
Street Address
2696 Nootka St.
City
Vancouver
State
B.C
ZipCode
V5M 3M5
Pharmacist Counseling Corner

Bronchial Soothe by Enzymatic Therapy: Common Questions

Does Bronchial Soothe by Enzymatic Therapy interact with any medications?
Yes. Based on its ingredients, Bronchial Soothe has a known interaction with 280 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bronchial Soothe contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bronchial Soothe is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bronchial Soothe label
Sources

Sources & How We Checked

Bronchial Soothe's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

English Ivy 13 references
  1. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  2. Fazio S, Pouso J, Dolinsky D, et al. Tolerance, safety and efficacy of Hedera helix extract in inflammatory bronchial diseases under clinical practice conditions: a prospective, open, multicentre postmarketing study in 9657 patients. Phytomedicine 2009;16 PubMed
  3. García M, Fernández E, Navarro JA, et al. Allergic contact dermatitis from Hedera helix L. Contact Dermatitis 1995;33(2):133-4.
  4. Hausen BM, Brohan J, Konig WA, et al. Allergic and irritant contact dermatitis from falcarinol and didehydrofalcarinol in common ivy (Hedera helix L.). Contact Dermatitis 1987;17(1):1-9.
  5. Mitchell, J. C. Allergic contact dermatitis from Hedera helix and Brassaia actinophylla (Araliaceae). Contact Dermatitis 1981;7(3):158-159.
  6. Boyle J, Harman RM. Contact dermatitis to Hedera helix (common ivy). Contact Dermatitis 1985;12(2):111-112. PubMed
  7. Yesudian PD, Franks A. Contact dermatitis from Hedera helix in a husband and wife. Contact Dermatitis 2002;46(2):125-126.
  8. Bregnbak D, Menné T, Johansen JD. Airborne contact dermatitis caused by common ivy (Hedera helix L. ssp. helix). Contact Dermatitis. 2015;72(4):243-4.
  9. Jones JM, White IR, White JM, McFadden JP. Allergic contact dermatitis to English ivy (Hedera helix)--a case series. Contact Dermatitis. 2009 Mar;60(3):179-80.
  10. Lurquin E, Swinnen I, Goossens A. Allergic contact dermatitis caused by Hedera helix arborescens and not by Hedera helix L. Contact Dermatitis. 2012;66(6):352-3.
  11. Paulsen E, Christensen LP, Andersen KE. Dermatitis from common ivy (Hedera helix L. subsp. helix) in Europe: past, present, and future. Contact Dermatitis. 2010;62(4):201-9.
  12. Rehman SU, Kim IS, Choi MS, Kim SH, Zhang Y, Yoo HH. Time-dependent Inhibition of CYP2C8 and CYP2C19 by Hedera helix Extracts, A Traditional Respiratory Herbal Medicine. Molecules. 2017;22(7). PubMed
  13. Kruttschnitt E, Wegener T, Zahner C, Henzen-Bücking S. Assessment of the Efficacy and Safety of Ivy Leaf (Hedera helix) Cough Syrup Compared with Acetylcysteine in Adults and Children with Acute Bronchitis. Evid Based Complement Alternat Med. 2020 May 4;2

See these in context on the English Ivy monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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