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Dietary supplement

Cactus Grandiflorus Ingredients & Drug Interactions

by Herb Pharm

Cactus Grandiflorus label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cactus Grandiflorus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cactus Grandiflorus is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for heart palpitations, mild heart symptoms, anxiety and nervous tension.Based on those ingredients, 10 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cactus grandiflorus Stem Extract, Fresh, Undried. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cactus Grandiflorus by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Cactus Grandiflorus by Herb Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cactus Grandiflorus by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: cactus grandiflorus stem extract made from fresh, undried plant material. It also contains cane alcohol as an inactive ingredient to preserve and deliver the extract.

Cactus grandiflorus has a long history in herbal traditions for supporting heart and circulatory health, though the specific mechanisms aren't fully characterized in modern research.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: heart and circulatory system support.
  • We looked for evidence on: heart palpitations, cardiac function, circulatory health.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We don't hold effectiveness ratings for cactus grandiflorus in our data, so we can't tell you how strong the evidence is for what this product claims to do. That doesn't mean it doesn't work — it means the evidence base we track isn't established here.

The evidence, ingredient by ingredient Cereus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Safety data for cactus grandiflorus is limited, and because it affects the heart, professional guidance is important before you start it. Some people taking it orally have reported burning of the mouth, queasiness, nausea, vomiting, and diarrhea.

If applied to skin, it may cause itching and pustules. There isn't enough safety information to use cactus grandiflorus during pregnancy or while breastfeeding.

Talk with your doctor or pharmacist if you're pregnant, nursing, or planning to become pregnant.

Side effects, ingredient by ingredient Cereus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cereus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 10 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start cactus grandiflorus, double-check with your doctor or pharmacist if you take digoxin or any MAOI antidepressants — both carry Moderate severity interactions. Use the medication search tool below to confirm your exact prescriptions aren't affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Cactus grandiflorus is marketed for heart health, but its safety profile is limited and it interacts with important heart and psychiatric medications. If you take digoxin or any MAOI antidepressant, check with your doctor or pharmacist before adding this product.

Anyone with a heart condition or taking multiple medications should review their full list with their own healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cactus Grandiflorus, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090700001216
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 307457
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cactus Grandiflorus by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
0.7 mL
Servings per container
168
UPC/BARCODE
090700001216
IngredientAmount% DV
Cactus grandiflorus Stem Extract, Fresh, Undried632 mg--

Other ingredients: Cane Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use Shake well before using Add 1 full squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 4 times per day. Best taken between meals.

Precautions

Caution: Do not exceed recommended serving.

Use with caution in persons taking heart medications.

Keep out of the reach of children

Storage

Store away from heat & light

Formula

Selenicereus sp.

Cactus Grandiflorus Liquid Extract

Prepared from the fresh (undried) steam of Selenicereus sp. cactus which is responsibly harvested from naturalized stands.

Formulation

System restoration Cardio & circulatory

Gluten-free

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cactus Grandiflorus by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cactus Grandiflorus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cactus Grandiflorus by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container168 Amounts shown are per serving.

Cactus grandiflorus Stem Extract, Fresh, Undried

Interacts with
10 drugs
632 mg per serving

Cereus (often called night-blooming cereus) is a cactus traditionally used in folk and homeopathic medicine for heart-related complaints like palpitat...

Cactus grandiflorus Stem Extract, Fresh, Undried monograph & interactions

Other (inactive) ingredients: Cane Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cactus Grandiflorus by Herb Pharm Drug Interactions

Want to check YOUR meds against Cactus Grandiflorus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
10Drugs
10 Moderate

Ingredients driving the most interactions

Cactus grandiflorus Stem Extract, Fresh, Undried 10

Individual Drug Interactions

The ingredients in Cactus Grandiflorus interact with 10 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cactus Grandiflorus interact with drugs. Each result below shows which ingredient is responsible. Cactus grandiflorus Stem Extract, Fresh, Undried

Each ingredient & the kinds of drugs it affects

For each ingredient in Cactus Grandiflorus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cactus grandiflorus Stem Extract, Fresh, Undried2 drug types · 10 drugs

Digoxin (Lanoxin)

Cereus may potentiate the actions of cardiac glycosides and may enhance the effect of other cardiac drugs.

Likelihood Possible Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, excessive doses of cereus may interact with MAOIs, because of the tyramine content.

Likelihood Possible Evidence D
Cactus grandiflorus Stem Extract, Fresh, Undried full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cactus Grandiflorus, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Cactus Grandiflorus by Herb Pharm: Common Questions

Does Cactus Grandiflorus by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Cactus Grandiflorus has a known interaction with 10 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cactus Grandiflorus contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this if I'm pregnant or breastfeeding?
There isn't enough safety data to know whether cactus grandiflorus is safe during pregnancy or breastfeeding. Talk with your doctor or pharmacist before using it if you're pregnant, nursing, or planning to become pregnant.
What side effects might I notice?
Taken by mouth, some people have experienced burning of the mouth, queasiness, nausea, vomiting, and diarrhea. If you apply it to skin, it may cause itching and pustules.
Why is there a warning about heart safety?
Cactus grandiflorus affects the heart and can interact with digoxin and other cardiac drugs. Because safety data is limited and the heart is sensitive, professional guidance is important before starting it.
What is cane alcohol doing in the product?
Cane alcohol is an inactive ingredient used to preserve and deliver the active cactus extract in liquid form.
Is this proven to work?
We don't have effectiveness ratings for cactus grandiflorus in our data. Traditionally it's been used for heart and circulatory health, but we can't comment on how strong the modern evidence is.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cactus Grandiflorus is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cactus Grandiflorus label
Go deeper

The Full Monographs Behind Cactus Grandiflorus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cereus

Interacts with 10 drugs

Cereus (often called night-blooming cereus) is a cactus traditionally used in folk and homeopathic medicine for heart-related complaints like palpitations. High-quality human evidence suppor...

Read the full Cereus monograph →
Sources

Sources & How We Checked

Cactus Grandiflorus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cereus 3 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.

See these in context on the Cereus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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