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Dietary supplement

California Poppy Ingredients & Drug Interactions

by Hawaii Pharm

California Poppy label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking California Poppy against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

California Poppy is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, trouble sleeping (insomnia), mild aches and pains.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic California Poppy extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against California Poppy by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with California Poppy by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of California Poppy by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: certified organic California Poppy extract. The liquid form also includes vegetable palm glycerin, pharmaceutical-grade alcohol, and artesian Hawaiian purified water as inactive ingredients to deliver the extract.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: anxiety and sleep support.
  • We looked for evidence on: Anxiety, Insomnia, nervous tension, restlessness.
  • The closest evidence on file: California Poppy is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: California Poppy is rated "Insufficient Reliable Evidence To Rate" for Insomnia.

The evidence for California poppy isn't yet established in the data we hold. The product has been used traditionally for anxiety, insomnia, and bedwetting in children, but the research is insufficient to rate how well it actually works for any of these uses.

If you're thinking about it for one of those reasons, talk it through with your doctor or pharmacist to see if there's a better-supported option for you.

The evidence, ingredient by ingredient California Poppy

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

California poppy is generally well tolerated for short-term use, but human safety data are limited. When used as a stand-alone ingredient in studies, side effects haven't been thoroughly documented.

In combination products containing hawthorn and magnesium, a small number of users reported muscular stiffness, morning fatigue, and nausea — though it's unclear whether those came from the California poppy, the other ingredients, or their combination. The safety data advise against use during pregnancy and breastfeeding.

Because information is scarce, talk with your doctor or pharmacist for personalized guidance if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient California Poppy

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — California Poppy.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on any CNS depressants — that's sedatives, sleep aids, anti-anxiety drugs, or certain pain medications. California poppy can increase their sedative effects (Moderate interaction), which may leave you drowsier or less sharp than expected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

California Poppy by Hawaii Pharm is traditionally used for sleep and calm, but the evidence for how well it works isn't firm yet. If you take sedatives or sleep aids, you'll want to check with your doctor or pharmacist before adding this — it can boost sedative effects.

The safety data on long-term use are limited, so it's best to view this as a short-term option and talk it over with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about California Poppy, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 0787699226460
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 23, 2020
DSLD ID 237946
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for California Poppy by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
0787699226460
IngredientAmount% DV
certified organic California Poppy extract970 mg--

Other ingredients: Vegetable Palm Glycerin, pharmaceutical grade Alcohol, artesian Hawaiian purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no GMO, gluten, artificial colors, heavy metals, preservatives, pesticides, fertilizers.

Super concentrated liquid herbal extract. Dry herb/menstruum ratio: 1:3.

Manufactured in an FDA registered facility.

Non GMO Gluten free

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops (0.7-1 ml, one full squeeze of the dropper bulb) to 2-4 oz of juice or water up to 4 times per day.

Precautions

Warning: Keep out of the reach of children.

May have contraindications. We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing or taking any medications.

Do not use if seal is broken or missing.

Storage

Store in a cool dry place.

Formula

(Eschscholzia californica)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

California Poppy by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

California Poppy label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in California Poppy by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Certified organic California Poppy extract

Interacts with
248 drugs
970 mg per serving

California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs. Human research is...

Certified organic California Poppy extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Pharmaceutical grade Alcohol, Artesian Hawaiian purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

California Poppy by Hawaii Pharm Drug Interactions

Want to check YOUR meds against California Poppy?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Moderate

Ingredients driving the most interactions

certified organic California Poppy extract 248

Individual Drug Interactions

The ingredients in California Poppy interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in California Poppy interact with drugs. Each result below shows which ingredient is responsible. certified organic California Poppy extract

Each ingredient & the kinds of drugs it affects

For each ingredient in California Poppy with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic California Poppy extract1 drug type · 248 drugs

Cns Depressants

Theoretically, taking California poppy with drugs with sedative effects may increase the risk of sedative effects.
Laboratory research shows that California poppy has sedative effects.

Likelihood Possible Evidence D
certified organic California Poppy extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for California Poppy, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

California Poppy by Hawaii Pharm: Common Questions

Does California Poppy by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, California Poppy has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
California Poppy contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a sleep aid or anti-anxiety medication?
Not without checking first. California poppy can boost the sedative effects of these drugs, which might make you too drowsy or impair your thinking. Check with your doctor or pharmacist about your specific medications before taking this product.
Is California Poppy safe to use long-term?
The evidence is limited. It's generally considered mild for short-term use, but human safety data for long-term use aren't established yet. Talk with your doctor or pharmacist about how long you should take it.
Can I take this while pregnant or breastfeeding?
The safety data advise against it — there isn't enough information either way. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist for personalized advice.
What side effects should I watch for?
Limited data exist on side effects when used alone. In studies combining it with hawthorn and magnesium, a small number of people reported morning fatigue, nausea, and muscular stiffness — though it's unclear if those came from the California poppy or the other ingredients.
Does California Poppy actually help with sleep or anxiety?
It's been used traditionally for both, but the research we have isn't firm enough to confirm how well it works. If you're looking for sleep or anxiety relief, talk with your doctor or pharmacist about what's best supported for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if California Poppy is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

California Poppy label
Go deeper

The Full Monographs Behind California Poppy’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

California Poppy

Interacts with 248 drugs

California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs. Human research is very limited, so its true benefits are...

Read the full California Poppy monograph →
Sources

Sources & How We Checked

California Poppy's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

California Poppy 3 references
  1. Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate
  2. Paul LD, Springer D, Staack RF, et al. Cytochrome P450 isoenzymes involved in rat liver microsomal metabolism of californine and protopine. Eur J Pharmacol 2004;485:69-79. PubMed
  3. Paul LD, Maurer HH. Studies on the metabolism and toxicological detection of the Eschscholtzia californica alkaloids californine and protopine in urine using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2003;789:43-5

See these in context on the California Poppy monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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