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Dietary supplement

California Poppy Ingredients & Drug Interactions

by Herbal Terra

California Poppy label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking California Poppy against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

California Poppy is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, trouble sleeping (insomnia), mild aches and pains.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic California Poppy (Eschscholzia californica) dried seed liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against California Poppy by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with California Poppy by Herbal Terra — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of California Poppy by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: certified organic California Poppy seed liquid extract. It's traditionally used to support relaxation and sleep, though the science behind those uses isn't yet established.

The liquid is made with a menstruum — a liquid base used to extract and preserve the herb.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient California Poppy product and its label doesn't state a use — see California Poppy's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for California Poppy isn't established yet. We don't have reliable data to say whether it actually works for anxiety, insomnia, or bedwetting — it's been used that way traditionally, but the clinical evidence just isn't there to back it up.

If you're considering it for any of those reasons, talk it over with your doctor or pharmacist about what the research does and doesn't show.

The evidence, ingredient by ingredient California Poppy

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

California Poppy is generally well tolerated for short-term use, though human safety data are limited. When it's been used in combination with other herbs like hawthorn and magnesium, a small number of people reported muscular stiffness, morning fatigue, and nausea — but it's unclear whether California Poppy itself was the cause.

There isn't enough safety data to recommend this product during pregnancy or breastfeeding. If you're pregnant, nursing, or planning to be, talk with your doctor or pharmacist before taking it.

Side effects, ingredient by ingredient California Poppy

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — California Poppy.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this product, double-check any medications that depress your central nervous system — sleep aids, anti-anxiety drugs, sedating pain relievers, and similar medications. Laboratory research shows California Poppy has sedative effects, so combining it with these drugs could strengthen drowsiness and reduce alertness.

Altogether, these interactions span 248 individual medications. Use the search tool below to look up your exact prescriptions and over-the-counter meds.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

California Poppy is a single-herb liquid extract marketed for relaxation and sleep, though solid evidence for either use isn't established yet. The main concern is with sedative drugs — it may amplify their effects.

If you take any medication that makes you sleepy or calms your nervous system, check with your doctor or pharmacist first. The same goes if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about California Poppy, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7429523686646
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 234584
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for California Poppy by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
7429523686646
IngredientAmount% DV
certified organic California Poppy (Eschscholzia californica) dried seed liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Origin of plant material: USA.

Manufactured in the USA in an FDA registered facility

Alcohol free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Alcohol-free liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Eschscholzia californica

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

California Poppy by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

California Poppy label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in California Poppy by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Certified organic California Poppy (Eschscholzia californica) dried seed liquid extract

Interacts with
248 drugs
970 mg per serving

California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs. Human research is...

Certified organic California Poppy (Eschscholzia californica) dried seed liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

California Poppy by Herbal Terra Drug Interactions

Want to check YOUR meds against California Poppy?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Moderate

Ingredients driving the most interactions

certified organic California Poppy (Eschscholzia californica) dried seed liquid extract 248

Individual Drug Interactions

The ingredients in California Poppy interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in California Poppy interact with drugs. Each result below shows which ingredient is responsible. certified organic California Poppy (Eschscholzia californica) dried seed liquid extract

Each ingredient & the kinds of drugs it affects

For each ingredient in California Poppy with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic California Poppy (Eschscholzia californica) dried seed liquid extract1 drug type · 248 drugs

Cns Depressants

Theoretically, taking California poppy with drugs with sedative effects may increase the risk of sedative effects.
Laboratory research shows that California poppy has sedative effects.

Likelihood Possible Evidence D
certified organic California Poppy (Eschscholzia californica) dried seed liquid extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for California Poppy, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

California Poppy by Herbal Terra: Common Questions

Does California Poppy by Herbal Terra interact with any medications?
Yes. Based on its ingredients, California Poppy has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
California Poppy contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will California Poppy help me sleep?
California Poppy has been used traditionally for sleep, and lab studies show it has sedative effects. But we don't have reliable clinical evidence yet that it actually improves insomnia in people. Talk with your doctor about whether it's worth trying for your situation.
Can I take this if I'm on a sleep aid or anti-anxiety medication?
You shouldn't combine this without checking first. California Poppy may strengthen the sedative effects of those drugs, making you much drowsier or less alert than intended. Check with your doctor or pharmacist before taking them together.
Is it safe to use while I'm pregnant or breastfeeding?
There isn't enough safety data to recommend it during pregnancy or breastfeeding. Talk with your doctor or pharmacist about whether it's okay for your situation — they can weigh the unknowns against what you need.
What are the side effects?
Human safety data are limited, so we don't have a full picture yet. In studies where it was combined with other herbs, a small number of people reported muscular stiffness, morning fatigue, and nausea — though it's not clear California Poppy itself was responsible.
How is this product made?
It's a liquid extract of dried California Poppy seed, made with certified organic plants. The liquid base is called a menstruum — it's what the herb is steeped in to pull out its active compounds and keep them stable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if California Poppy is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

California Poppy label
Go deeper

The Full Monographs Behind California Poppy’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

California Poppy

Interacts with 248 drugs

California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs. Human research is very limited, so its true benefits are...

Read the full California Poppy monograph →
Sources

Sources & How We Checked

California Poppy's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

California Poppy 3 references
  1. Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate
  2. Paul LD, Springer D, Staack RF, et al. Cytochrome P450 isoenzymes involved in rat liver microsomal metabolism of californine and protopine. Eur J Pharmacol 2004;485:69-79. PubMed
  3. Paul LD, Maurer HH. Studies on the metabolism and toxicological detection of the Eschscholtzia californica alkaloids californine and protopine in urine using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2003;789:43-5

See these in context on the California Poppy monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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