Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Carb Phaser 1000 Ingredients & Drug Interactions

by BioChem Sports

Carb Phaser 1000 label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Carb Phaser 1000 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Carb Phaser 1000 is a dietary supplement by BioChem Sports with 4 active ingredients. Its ingredients are commonly taken for blood sugar support in type 2 diabetes, weight loss and appetite control, insulin sensitivity.Based on those ingredients, 1,228 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gymnema Sylvestre, Niacin, Chromium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Carb Phaser 1000 by BioChem Sports

Ask about any prescription or over-the-counter medication and we check it for interactions with Carb Phaser 1000 by BioChem Sports — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Carb Phaser 1000 by BioChem Sports

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Carb Phaser 1000 has 4 active ingredients. Chromium supports normal blood sugar control and is likely effective for chromium deficiency, though it's only possibly effective for diabetes.

Niacin (also called vitamin B3) plays a role in energy metabolism and is likely effective for pellagra; the product also contains niacin for its metabolic effects. Gymnema sylvestre is an herbal extract traditionally used for blood sugar support, but the evidence for it isn't established in our data.

White kidney bean extract rounds out the formula — we don't hold interaction data for it. The capsules also contain inactive ingredients: cellulose, gum arabic, magnesium stearate, and silica.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Blood sugar and carbohydrate management support.
  • We looked for evidence on: Diabetes, Hypoglycemia, Impaired glucose tolerance (Prediabetes), Metabolic syndrome, Antiretroviral-induced insulin resistance, Chromium deficiency — and 4 related terms.
  • The strongest evidence on file: Chromium is rated "Likely Effective" for Chromium deficiency (Natural Medicines).
  • Also on file: Niacin is rated "Possibly Effective" for Metabolic syndrome.
  • Also on file: Chromium is rated "Possibly Effective" for Diabetes.

Chromium in this product is likely effective for chromium deficiency and possibly effective for diabetes, though it's possibly ineffective for prediabetes and other conditions listed in the research. Niacin is likely effective for pellagra and possibly effective for metabolic syndrome and HIV-related cholesterol issues.

Gymnema sylvestre has insufficient reliable evidence in our data to rate its effectiveness for diabetes, prediabetes, obesity, or metabolic syndrome — we simply don't have enough solid research to say whether it works for these purposes. The overall effectiveness of the combination for carb management isn't established in the product facts we hold.

The evidence, ingredient by ingredient Chromium Niacin Gymnema

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chromium is generally well tolerated at typical supplement doses, though high or long-term doses may pose risks for some people. Most common side effects from chromium are gastrointestinal irritation, headaches, insomnia, and mood changes; rare serious effects include kidney and liver damage.

Skin rashes and contact dermatitis have also been reported. Niacin is well tolerated in food amounts and at monitored prescription doses, but high supplemental doses commonly cause flushing, stomach upset, and elevated liver enzymes — up to 70% of people taking larger doses experience flushing.

Rare serious effects include liver damage, muscle damage, and vision changes. Gymnema is generally well tolerated short-term, but it can lower blood sugar, and a rare case of drug-induced hepatitis has been reported.

For pregnancy, chromium is likely safe and possibly safe, and small amounts from food or prenatal vitamins are acceptable — but extra supplement doses should be avoided unless your doctor recommends them. Niacin is likely safe in pregnancy and lactation at normal dietary amounts, but high-dose niacin should be avoided unless prescribed.

Gymnema lacks enough safety data and should be avoided during pregnancy and while breastfeeding.

Side effects, ingredient by ingredient Chromium Niacin Gymnema

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Gymnema, Niacin, Chromium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,229 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting Carb Phaser 1000, check with your pharmacist if you take antidiabetes drugs or insulin (chromium and gymnema both may lower blood sugar further), levothyroxine (chromium may reduce its absorption), antihypertensive drugs (niacin may lower blood pressure), blood thinners or antiplatelet drugs (niacin may have additive effects), liver-toxic drugs (niacin adds risk), statins (niacin may increase muscle damage risk), gout medications like allopurinol or probenecid (niacin may reduce their effects), bile acid sequestrants (niacin binds them — space them 4 to 6 hours apart), or any drug metabolized by your liver's CYP1A2, CYP2C9, or CYP3A4 enzymes (gymnema may affect levels). NSAIDs and aspirin may slightly raise chromium levels, though this is minor.

No interactions are documented for white kidney bean extract in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're looking for carb management support and your doctor has ruled out chromium deficiency or prediabetes in you — but you'll want to talk with your pharmacist or doctor first if you take diabetes medications, thyroid medication, blood pressure drugs, blood thinners, or gout medications. The niacin dose here is modest, but it's still worth checking.

White kidney bean extract and gymnema are included, though we don't have strong effectiveness data for either in your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Carb Phaser 1000, straight from the product label.

Brand BioChem Sports
Market status On market
Date entered into DSLD Feb 25, 2013
DSLD ID 13210
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Carb Phaser 1000 by BioChem Sports, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
IngredientAmount% DV
Chromium100 mcg83%
White Kidney Bean extract500 mg--
Niacin0.5 mg3%
Gymnema Sylvestre300 mg--

Other ingredients: Cellulose, Gum Arabic, Cellulose, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Do not accept if seal is broken.

Keep out of the reach of children.

WARNING: Not for use by pregnant or nursing women. If you are diabetic or hypoglycemic, taking medication or planning a surgery, consult your doctor before using this product.

If any adverse reactions occur, stop taking the product and consult your doctor.

General

Product No. 1735 03M11L

Storage

Store between 59(0)-86(0) F.

Brand IP Statement(s)

ChromeMate(R) brand niacin-bound chromium. ChromeMate(R) is a registered trademark of InterHealth N.I.

(C)2011 Biochem

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

NO: Yeast, corn, wheat, soy, gluten, milk, salt, sugar, preservatives or artificial color.

Vegetarian Capsules

Seals/Symbols

Certified GF(R) Gluten-Free PLEASE RECYCLE Good Manufacturing Practices GMP CERTIFIED Our manufacturing supports wind power renewablechoice.com Certified Vegan AVA(TM) American Vegetarian Association CHROMEMATE(R)

K

General Statements

This product has been manufactured at an NSF GMP Registered facility.

Lot No: Best by:

Supports Glucose Metabolism

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take two (2) capsules twice daily with food. Do not exceed recommended dose. Use with a low-fat, reduced calorie diet and daily exercise program. As a reminder, discuss your diet and exercise plan and the supplements and medications that you take with your health care providers.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Carb Phaser 1000 by BioChem Sports label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Carb Phaser 1000 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Carb Phaser 1000 by BioChem Sports

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Chromium

Interacts with
178 drugs
100 mcg per serving Form: Chromium Polynicotinate

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

White Kidney Bean extract

500 mg per serving

Niacin

Interacts with
727 drugs
0.5 mg per serving Form: Chromium Polynicotinate

Niacin (vitamin B3) is an essential nutrient your body needs for energy and metabolism, and deficiency is uncommon in most developed countries. Prescr...

Niacin monograph & interactions

Gymnema Sylvestre

Interacts with
851 drugs
300 mg per serving Form: Gymnemic Acids

Gymnema is an Ayurvedic herb best known for possibly helping lower blood sugar and reducing the taste of sweetness on the tongue. Some early human stu...

Gymnema Sylvestre monograph & interactions

Other (inactive) ingredients: Cellulose, Gum Arabic, Cellulose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Carb Phaser 1000 by BioChem Sports Drug Interactions

Want to check YOUR meds against Carb Phaser 1000?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,228Drugs
828 Moderate 400 Minor

Ingredients driving the most interactions

Gymnema Sylvestre 851
Niacin 727
Chromium 178

Individual Drug Interactions

The ingredients in Carb Phaser 1000 interact with 1,228 drugs. Click any drug to see the details.

3 of the 4 ingredients in Carb Phaser 1000 interact with drugs. Each result below shows which ingredient is responsible. Gymnema Sylvestre Niacin Chromium

Each ingredient & the kinds of drugs it affects

For each ingredient in Carb Phaser 1000 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Gymnema Sylvestre6 drug types · 851 drugs

Antidiabetes Drugs

Theoretically, taking gymnema with antidiabetes drugs might increase the risk of hypoglycemia.
Gymnema reduces blood glucose levels in some human and animal research. In human studies, it has been shown to enhance the blood glucose lowering effects of hypoglycemic drugs. However, other research in adults with prediabetes or metabolic syndrome suggests that gymnema does not reduce fasting levels of blood glucose. Until more is known, monitor blood glucose levels closely.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Animal and in vitro research shows that gymnema can inhibit the CYP1A2 enzyme. In one animal study, oral administration of gymnema for 7 days increased the plasma concentrations of phenacetin, a CYP1A2 substrate, by about 1.4-fold and reduced the clearance of phenacetin by about 29%.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, gymnema might increase or decrease levels of drugs metabolized by CYP2C9.
Animal research shows that gymnema can induce the CYP2C9 enzyme. In one animal study, gymnema caused a 2.4-fold increase in the clearance of tolbutamide, a CYP2C9 substrate, in rats. In vitro research also shows that gymnema can inhibit CYP2C9.

Likelihood Possible Evidence D
Phenacetin

Theoretically, taking gymnema with phenacetin might increase the levels of phenacetin.
Animal research shows that gymnema, administered orally for 7 days, decreases the clearance of phenacetin in a dose-dependent manner by about 21% to 29% and increases plasma levels about 1.3- to 1.4-fold when compared to control.

Likelihood Possible Evidence D
Tolbutamide (Orinase)

Theoretically, taking gymnema with tolbutamide might the decrease levels of tolbutamide.
Animal research shows that gymnema, administered orally for 7 days, increases the clearance of tolbutamide by 2.4-fold when compared to control.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
One in vitro study using rat liver microsomes shows that gymnema can modestly inhibit the CYP3A4 enzyme. However, other in vitro research using human liver microsomes shows that gymnema does not affect CYP3A4 activity. Animal research also shows that gymnema does not alter the function of CYP3A4. In one study in rats, oral administration of gymnema for 7 days did not alter the clearance of amlodipine, a CYP3A4 substrate.

Likelihood Unlikely Evidence D
Gymnema Sylvestre full monograph & interactions

Niacin15 drug types · 727 drugs

Alcohol (Ethanol)

Concomitant use of alcohol and niacin might increase the risk of flushing and hepatotoxicity.
Alcohol can exacerbate the flushing and pruritus associated with niacin. Large doses of niacin might also exacerbate liver dysfunction associated with chronic alcohol use. A case report describes delirium and lactic acidosis in a patient taking niacin 3 grams daily who ingested 1 liter of wine. Advise patients to avoid large amounts of alcohol while taking niacin.

Likelihood Probable Evidence D
Allopurinol (Zyloprim)

Theoretically, niacin might antagonize the therapeutic effects of uricosurics such as allopurinol.
Large doses of niacin can reduce urinary excretion of uric acid, potentially resulting in hyperuricemia. Doses of uricosurics such as allopurinol might need to be increased to maintain control of gout in patients who start taking niacin. People who have frequent attacks of gout despite uricosuric therapy should avoid niacin.

Likelihood Probable Evidence C
Anticoagulant/Antiplatelet Drugs

Theoretically, niacin may have additive effects when used with anticoagulant or antiplatelet drugs.
Several cases of clotting factor synthesis deficiency and coagulopathy have been reported in patients taking sustained-release niacin. Also, thrombocytopenia has been reported in patients treated with niacin or niacin plus lovastatin.

Likelihood Possible Evidence D
Antidiabetes Drugs

Niacin can increase blood glucose levels and may diminish the effects of antidiabetes drugs.
Niacin impairs glucose tolerance in a dose-dependent manner, probably by causing or aggravating insulin resistance and increasing hepatic production of glucose. In diabetes patients, niacin 4.5 grams daily for 5 weeks can increase plasma glucose by an average of 16% and glycated hemoglobin (HbA1c) by 21%. However, lower doses of 1.5 grams daily or less appear to have minimal effects on blood glucose. In some patients, glucose levels increase when niacin is started, but then return to baseline when a stable dose is reached. Up to 35% of patients with diabetes may need adjustments in hypoglycemic therapy when niacin is added.

Likelihood Probable Evidence B
Antihypertensive Drugs

Theoretically, niacin may increase the risk of hypotension when used with antihypertensive drugs.
The vasodilating effects of niacin can cause hypotension. Furthermore, some clinical evidence suggests that a one-hour infusion of niacin can reduce systolic, diastolic, and mean blood pressure in hypertensive patients. This effect is not observed in normotensive patients.

Likelihood Possible Evidence B
Bile Acid Sequestrants

Bile acid sequestrants can bind niacin and decrease absorption. Separate administration by 4-6 hours to avoid an interaction.
In vitro studies show that colestipol (Colestid) binds about 98% of available niacin and cholestyramine (Questran) binds 10% to 30%.

Likelihood Possible Evidence D
Gemfibrozil (Lopid)

Theoretically, concomitant use of niacin and gemfibrozil might increase the risk of myopathy in some patients.
A case of myopathy from concomitant use of niacin and gemfibrozil has been reported. Niacin alone has also been associated with cases of myopathy. Using gemfibrozil with niacin might further increase the risk of developing myopathy.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, concomitant use of niacin and hepatotoxic drugs might increase the risk of hepatotoxicity.
Niacin has been associated with cases of liver toxicity, especially when used in pharmacologic doses. Sustained-release niacin preparations appear to be associated with a higher risk of hepatotoxicity than immediate-release niacin.

Likelihood Possible Evidence D
Hmg-Coa Reductase Inhibitors ("Statins")

Theoretically, concomitant use of niacin and statins might increase the risk of myopathy and rhabdomyolysis in some patients.
Some case reports have raised concerns that niacin might increase the risk of myopathy and rhabdomyolysis when combined with statins. However, a significantly increased risk of myopathy has not been demonstrated in clinical trials, including those using an FDA-approved combination of lovastatin and niacin (Advicor).

Likelihood Possible Evidence D
Probenecid (Benemid)

Theoretically, niacin might antagonize the therapeutic effects of uricosurics such as probenecid.
Large doses of niacin reduce urinary excretion of uric acid, potentially causing hyperuricemia. Doses of uricosurics such as probenecid might need to be increased to maintain control of gout in patients who start taking niacin. People who have frequent attacks of gout despite uricosuric therapy should avoid niacin.

Likelihood Probable Evidence C
Sulfinpyrazone (Anturane)

Theoretically, niacin might antagonize the therapeutic effects of uricosurics such as sulfinpyrazone.
Large doses of niacin reduce urinary excretion of uric acid, potentially causing hyperuricemia. Doses of uricosurics such as sulfinpyrazone might need to be increased to maintain control of gout in patients who start taking niacin. People who have frequent attacks of gout despite uricosuric therapy should avoid niacin.

Likelihood Probable Evidence C
Thyroid Hormone

Theoretically, niacin might antagonize the therapeutic effects of thyroid hormones.
Clinical research and case reports suggests that taking niacin can reduce serum levels of thyroxine-binding globulin by up to 25% and moderately reduce levels of thyroxine (T4). Patients taking thyroid hormone for hypothyroidism might need dose adjustments when using niacin.

Likelihood Probable Evidence D
Transdermal Nicotine (Nicoderm)

Theoretically, concomitant use of niacin and transdermal nicotine might increase the risk of flushing and dizziness.
Niacin and nicotine can both cause flushing and dizziness.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that niacin may increase the anticoagulant effects of warfarin.
In a case report, a patient on warfarin developed an elevated international normalized ratio (INR) of 3.9 after taking niacin for two weeks. The patient's INR was previously stable, ranging between 2 and 3 in recent months, and no other medication changes were identified. The elevated INR returned to therapeutic range within 4 days following the discontinuation of niacin.

Likelihood Possible Evidence D
Aspirin

Large doses of aspirin might alter the clearance of niacin.
Aspirin is often used with niacin to reduce niacin-induced flushing. Doses of 80-975 mg aspirin have been used, but 325 mg appears to be optimal. Aspirin also seems to reduce the clearance of niacin by competing for glycine conjugation. Taking aspirin 1 gram seems to reduce niacin clearance by 45%. This is probably a dose-related effect and not clinically significant with the more common aspirin dose of 325 mg.

Likelihood Likely Evidence B
Niacin full monograph & interactions

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Carb Phaser 1000, from the product label.

BioChem Sports

See all BioChem Sports products
Name
Country Life, LLC (Biochem)
Street Address
180 Vanderbilt Motor Parkway
City
Hauppauge
State
NY
ZipCode
11788
Web Address
www.biochem-fitness.com
Pharmacist Counseling Corner

Carb Phaser 1000 by BioChem Sports: Common Questions

Does Carb Phaser 1000 by BioChem Sports interact with any medications?
Yes. Based on its ingredients, Carb Phaser 1000 has a known interaction with 1,228 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Carb Phaser 1000 contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have diabetes or prediabetes?
Not without talking to your doctor or pharmacist first. Both chromium and gymnema can lower blood sugar, and if you're already on diabetes medication, that could increase your risk of low blood sugar. Chromium is only possibly effective for diabetes anyway, and we don't have solid evidence that gymnema works for prediabetes or diabetes.
Will this interact with my thyroid medication?
Yes, possibly. Chromium may bind levothyroxine (Synthroid) in your digestive tract and reduce how much you absorb by about 17%. If you take levothyroxine, ask your pharmacist how far apart to space it from this supplement.
What are the most common side effects I might notice?
From chromium, you might get gastrointestinal irritation, headaches, insomnia, or mood changes. Niacin commonly causes flushing (affecting up to 70% of people at larger doses), stomach upset, and nausea — these usually improve within two weeks. Gymnema may lower blood sugar and is generally well tolerated short-term.
Is niacin in this product going to give me the flushing sensation?
It depends on the dose and how sensitive you are. Flushing can happen even at doses as low as 30 mg daily, but it's more common at higher doses. We don't have the exact niacin dose in this product listed in the facts, so ask your pharmacist if it's likely to cause this effect.
Can I take this if I'm pregnant or breastfeeding?
Chromium is likely safe in pregnancy and possibly safe, and small amounts from food or prenatal vitamins are fine — but extra supplement doses should be avoided unless your doctor says it's okay. Niacin is likely safe at normal dietary amounts. Gymnema, however, lacks enough safety data and should be avoided during pregnancy and while breastfeeding — talk to your doctor about whether this product is right for you.
Does this actually work for managing carbs?
Chromium is likely effective for chromium deficiency and possibly effective for diabetes, though only possibly ineffective for prediabetes. Niacin's role here is mainly nutritional. Gymnema doesn't have enough reliable evidence in our data to say whether it works for diabetes or prediabetes. This isn't a substitute for medical diabetes care.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Carb Phaser 1000 label
Go deeper

The Full Monographs Behind Carb Phaser 1000’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph → Herb & supplement monograph

Niacin

Interacts with 727 drugs

Niacin (vitamin B3) is an essential nutrient your body needs for energy and metabolism, and deficiency is uncommon in most developed countries. Prescription-strength niacin has been used to...

Read the full Niacin monograph → Herb & supplement monograph

Gymnema

Interacts with 851 drugs

Gymnema is an Ayurvedic herb best known for possibly helping lower blood sugar and reducing the taste of sweetness on the tongue. Some early human studies are encouraging for blood sugar sup...

Read the full Gymnema monograph →
Sources

Sources & How We Checked

Carb Phaser 1000's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 131 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chromium 53 references
  1. Cerulli J, Grabe DW, Gauthier I, et al. Chromium picolinate toxicity. Ann Pharmacother 1998;32:428-31. PubMed
  2. Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism 1987;36:896-9. PubMed
  3. Mohamedshah FY, Moser-Veillon PB, Yamini S, et al. Distribution of a stable isotope of chromium (53Cr) in serum, urine, and breast milk in lactating women. Am J Clin Nutr 1998;67:1250-5. PubMed
  4. Wasser WG, Feldman NS, D'Agati VD. Chronic renal failure after ingestion of over-the-counter chromium picolinate. [letter]. Ann Intern Med 1997;126:410. PubMed
  5. Mertz W. Interaction of chromium with insulin: a progress report. Nutr Rev 1998;56:174-7. PubMed
  6. Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998;17:548-55. PubMed
  7. McLeod MN, Gaynes BN, Golden RN. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. J Clin Psych 1999;60:237-40. PubMed
  8. Fowler JF Jr. Systemic contact dermatitis caused by oral chromium picolinate. Cutis 2000;65:116. DOI
  9. Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness 1995;35:273-80.
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Niacin 66 references
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Gymnema 12 references
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