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Dietary supplement

Cassava (Tapioca) Powder Ingredients & Drug Interactions

by TerraVita Premium Collection

Cassava (Tapioca) Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cassava (Tapioca) Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cassava (Tapioca) Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for dietary staple/source of carbohydrates, fertility aid (to conceive twins), digestive support.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cassava, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cassava (Tapioca) Powder by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Cassava (Tapioca) Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cassava (Tapioca) Powder by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: cassava powder, made from the cassava root. Cassava is a starchy root vegetable used as food in many parts of the world.

The product has no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Cassava product and its label doesn't state a use — see Cassava's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for cassava powder's effectiveness isn't established in the data we hold. Studies haven't provided reliable evidence to rate it for diabetes, diarrhea-related dehydration, or other common uses.

That doesn't mean it doesn't work—it means the science isn't there yet to say one way or the other.

The evidence, ingredient by ingredient Cassava

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

This is where you need to be careful. Properly cooked cassava is eaten safely as a food, but raw or poorly processed cassava contains cyanogenic glycosides—compounds that can convert to cyanide (a poison) if not removed during processing.

Symptoms of cyanide poisoning include nausea, vomiting, stomach pain, diarrhea, dizziness, weakness, and headache. Large amounts or concentrated supplements aren't well studied and carry cyanide concerns beyond what food-grade cassava does.

Cassava intake has also been linked to an increased risk of low thyroid function (hypothyroidism) and goiter (enlarged thyroid). Rarely, people with a latex allergy have reported allergic reactions to cassava, including hives, swelling, difficulty breathing, and in severe cases anaphylaxis.

There isn't enough data to know whether this product is safe in pregnancy or while breastfeeding—talk with your doctor or pharmacist before use if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Cassava

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cassava.
  • The most serious interaction on file is rated Moderate.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take thyroid hormones (like levothyroxine for low thyroid function), double-check this product with your pharmacist before use—cassava can reduce how well your thyroid medication works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Cassava powder is a common food when properly cooked, but this concentrated supplement carries cyanide and thyroid concerns that food doesn't. If you take thyroid medication, check with your pharmacist first.

If you're pregnant, breastfeeding, or have a latex allergy, talk with your doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cassava (Tapioca) Powder, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435195274
Net contents 1 Ounce(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 284402
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cassava (Tapioca) Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.25 Teaspoon(s)
Servings per container
28
UPC/BARCODE
064435195274
IngredientAmount% DV
Cassava, Powder1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cassava (Tapioca) Powder by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cassava (Tapioca) Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cassava (Tapioca) Powder by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container28 Amounts shown are per serving.

Cassava, Powder

Interacts with
16 drugs
1000 mg per serving Form: Tapioca

Cassava is a starchy root vegetable that feeds millions of people worldwide, but it must be properly cooked or processed because the raw plant contain...

Cassava, Powder monograph & interactions
Interaction report

Cassava (Tapioca) Powder by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Cassava (Tapioca) Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Moderate

Ingredients driving the most interactions

Cassava, Powder 16

Individual Drug Interactions

The ingredients in Cassava (Tapioca) Powder interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cassava (Tapioca) Powder interact with drugs. Each result below shows which ingredient is responsible. Cassava, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Cassava (Tapioca) Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cassava, Powder1 drug type · 16 drugs

Thyroid Hormone

Evidence from human and animal research suggests that cassava root has marked antithyroid effects, particularly if poorly processed or if consumed as part of a protein-deficient diet. Also, clinical research shows that consuming boiled cassava leaves 200 grams twice daily for 9 days significantly reduces levels of the thyroid hormones triiodothyronine and thyroxine. Theoretically, cassava may alter thyroid function, reduce thyroid hormone levels, and interfere with thyroid hormone-replacement therapy.

Likelihood Possible Evidence D
Cassava, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cassava (Tapioca) Powder, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Cassava (Tapioca) Powder by TerraVita Premium Collection: Common Questions

Does Cassava (Tapioca) Powder by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Cassava (Tapioca) Powder has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cassava (Tapioca) Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this the same as eating cassava as a food?
Not quite. Cassava as a cooked food is eaten safely around the world. But this is a concentrated supplement powder, and concentrated forms aren't well studied. Food-grade cassava has lower cyanide risk because processing removes those compounds; a supplement gives you more in a smaller dose, so the safety profile is different.
Can cassava powder cause cyanide poisoning?
Raw or poorly processed cassava can contain cyanogenic glycosides that convert to cyanide if not removed. Symptoms include nausea, vomiting, stomach pain, diarrhea, dizziness, weakness, and headache. Properly processed cassava powder lowers that risk, but concentrated supplements still aren't well studied for safety, so they're best avoided.
Will this affect my thyroid medication?
Yes—cassava has a documented moderate interaction with thyroid hormones. It can reduce how well your thyroid medication works, especially if the cassava is poorly processed or your diet is low in protein. If you take thyroid medication, talk with your pharmacist before using this product.
Does cassava powder work for diabetes or diarrhea?
The evidence isn't established in the data we hold. Studies haven't provided reliable evidence to rate cassava powder for those uses, so we can't say whether it works.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data to know either way. The rating is 'possibly unsafe' for both pregnancy and breastfeeding, so talk with your doctor or pharmacist for personalized advice before use.
I have a latex allergy—is this safe for me?
That's a conversation for your doctor or pharmacist. Rarely, people with confirmed latex allergy have reported allergic reactions to cassava, including hives, swelling, and breathing difficulty. Your pharmacist can help you decide if it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cassava (Tapioca) Powder label
Go deeper

The Full Monographs Behind Cassava (Tapioca) Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cassava

Interacts with 16 drugs

Cassava is a starchy root vegetable that feeds millions of people worldwide, but it must be properly cooked or processed because the raw plant contains compounds that release cyanide. As a s...

Read the full Cassava monograph →
Sources

Sources & How We Checked

Cassava (Tapioca) Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cassava 30 references
  1. Hernandez T, Lundquist P, Oliveira L, et al. Fate in humans of dietary intake of cyanogenic glycosides from roots of sweet cassava consumed in Cuba. Nat Toxins 1995;3(2):114-7. PubMed
  2. Ariffin WA, Choo KE, Karnaneedi S. Cassava (ubi kayu) poisoning in children. Med J Malaysia 1992;47(3):231-4.
  3. Tylleskar T, Banea M, Bikangi N, et al. Cassava cyanogens and konzo, an upper motoneuron disease found in Africa. Lancet 1992;339(8787):208-11. PubMed
  4. Akindahunsi AA, Grissom FE, Adewusi SR, et al. Parameters of thyroid function in the endemic goitre of Akungba and Oke-Agbe villages of Akoko area of southwestern Nigeria. Afr J Med Med Sci 1998;27(3-4):239-42.
  5. Osman BA, Ng ML, Bakar AA, Khalid BA. The effect of cassava leave intake on thyroid hormone and urinary iodine. East Afr Med J 1993;70(5):314-5.
  6. Gaitan E, Cooksey RC, Legan J, et al. Antithyroid effects in vivo and in vitro of babassu and mandioca: a staple food in goiter areas of Brazil. Eur J Endocrinol 1994;131(2):138-44. PubMed
  7. Geelhoed GW. Metabolic maladaptation: individual and social consequences of medical intervention in correcting endemic hypothyroidism. Nutrition 1999;15(11-12):908-32. DOI
  8. Biassoni P, Ravera G, Bertocchi J, et al. Influence of dietary habits on thyroid status of a nomadic people, the Bororo shepherds, roaming a central African region affected by severe iodine deficiency. Eur J Endocrinol 1998;138(6):681-5. PubMed
  9. Delange F. The disorders induced by iodine deficiency. Thyroid 1994;4(1):107-28. PubMed
  10. Delange F. [The role of goitrogenic factors distinct from iodine deficiency in the etiology of goiter]. Ann Endocrinol (Paris) 1988;49(4-5):302-5.
  11. Assan R, Assan D, Thiebaut MF, et al. [Diabetogenic tropical pancreatitis]. Diabete Metab 1988;14(3):299-312.
  12. Balakrishnan V, Unnikrishnan AG, Thomas V, et al. Chronic pancreatitis. A prospective nationwide study of 1,086 subjects from India. JOP 2008;9(5):593-600.
  13. Cliff J, Lundqvist P, Martensson J, et al. Association of high cyanide and low sulphur intake in cassava-induced spastic paraparesis. Lancet 1985;2(8466):1211-3. PubMed
  14. Paula Cardoso A, Ernesto M, Nicala D, et al. Combination of cassava flour cyanide and urinary thiocyanate measurements of school children in Mozambique. Int J Food Sci Nutr 2004;55(3):183-90. PubMed
  15. Dumas M, Giordano C, Ndiaye IP, et al. [The concept of tropical neuromyelopathy]. Bull Soc Pathol Exot Filiales 1988;81(2):183-8.
  16. Tucker K, Hedges TR. Food shortages and an epidemic of optic and peripheral neuropathy in Cuba. Nutr Rev 1993;51(12):349-57. PubMed
  17. Wilson J. Cyanide in human disease: a review of clinical and laboratory evidence. Fundam Appl Toxicol 1983;3(5):397-9. DOI
  18. Grange AO. Evaluation of cassava-salt suspension in the management of acute diarrhoea in infants and children. J Diarrhoeal Dis Res 1994;12(1):55-8.
  19. Olusanya O, Olanrewaju DM, Oluwole FA. Studies on the effectiveness, safety and acceptability of fluids from local foodstuffs in the prevention and management of dehydration caused by diarrhoea in children. J Trop Pediatr 1994;40(6):360-4. PubMed
  20. Singh JD. The teratogenic effects of dietary Cassava on the pregnant albino rat: a preliminary report. Teratology 1981;24(3):289-91. PubMed
  21. Oforofuo IA, Omu AE. Serum thiocyanate levels in a normal population and in pregnancy in Benin City, Nigeria: preliminary report. Int J Gynaecol Obstet 1991;34(1):65-9. PubMed
  22. Nikolajsen T, Nielsen F, Rasch V, et al. Uterine contraction induced by Tanzanian plants used to induce abortion. J Ethnopharmacol 2011;137(1):921-5. PubMed
  23. Cardoso AP, Mirione E, Ernesto M, et al. Processing of cassava roots to remove cyanogens. Journal of Food Composition and Analysis 2005;18(5):451-60. DOI
  24. Dorea JG. Maternal thiocyanate and thyroid status during breast-feeding. J Am Coll Nutr 2004;23(2):97-101. PubMed
  25. Sánchez D, Sus S, Ortiz B, Sánchez J, Cardona R. Cross-reactivity Between Cassava and Latex in a Colombian Patient With an Anaphylactic Reaction. J Investig Allergol Clin Immunol. 2015;25(6):453-5.
  26. Rosa ML, Falcão PM, Yokoo EM, et al. Brazil's staple food and incident diabetes. Nutrition. 2014 Mar;30(3):365-8. Epub 2013 Oct 2. PubMed
  27. Banea JP, Bradbury JH, Mandombi C, et al. Control of konzo by detoxification of cassava flour in three villages in the Democratic Republic of Congo. Food Chem Toxicol. 2013 Oct;60:506-13. Epub 2013 Aug 11. PubMed
  28. Boivin MJ, Okitundu D, Makila-Mabe Bumoko G, et al. Neuropsychological effects of konzo: a neuromotor disease associated with poorly processed cassava. Pediatrics. 2013 Apr;131(4):e1231-9. Epub 2013 Mar 25. PubMed
  29. Antolin-Amerigo D, Rodriguez-Rodriguez M, Barbarroja-Escudero J, Postigo Resa I, Uribe-Etxebarría MC, Alvarez-Mon M. Hypersensitivity to cassava: an allergen-based assessment. J Investig Allergol Clin Immunol. 2012;22(5):385-6.
  30. Santos KS, Galvao CE, Gadermaier G, et al. Allergic reactions to manioc (Manihot esculenta Crantz): identification of novel allergens with potential involvement in latex-fruit syndrome. J Allergy Clin Immunol. 2011 Dec;128(6):1367-9. Epub 2011 Aug 19. PubMed

See these in context on the Cassava monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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