celltrient Ingredients & Drug Interactions
by Nestle Healthcare Nutrition
What is this page for?
First and foremost: checking celltrient against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
celltrient is a dietary supplement by Nestle Healthcare Nutrition with 2 active ingredients. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 295 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are N-Acetyl Cysteine, Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against celltrient by Nestle Healthcare Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with celltrient by Nestle Healthcare Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of celltrient by Nestle Healthcare Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Celltrient contains 2 active ingredients: glycine and N-acetyl cysteine (NAC). Glycine is an amino acid, and N-acetyl cysteine is a form of the amino acid cysteine.
The capsule also contains several inactive ingredients—cellulose-based materials and magnesium stearate—that help hold the capsule together and aid absorption.
Does it work?
Strong evidence
Glycine is rated possibly effective for schizophrenia, though evidence is limited. For other conditions listed—ADHD, benign prostatic hyperplasia, cystic fibrosis, and 3-phosphoglycerate dehydrogenase deficiency—there isn't enough reliable evidence to know whether it works.
N-acetyl cysteine is rated effective for acetaminophen poisoning, atelectasis (a collapsed lung condition), use in bronchial diagnostic studies, and tracheostomy care. It's rated possibly effective for bronchitis.
The evidence we hold doesn't establish that this product works for general wellness or any condition beyond those listed.
How safe is it?
Well-documented data
Glycine is generally well tolerated at typical doses, though long-term safety data are limited. The most common rare side effects are mild sedation, soft stools, nausea, vomiting, upper stomach discomfort, and dry mouth; these resolve quickly if you stop taking it.
N-acetyl cysteine is also generally well tolerated at typical doses you'd find in an oral supplement, though most adverse effects occur at very high doses (over 9 grams in a single dose or over 30 grams daily). Common side effects at typical doses are diarrhea, dry mouth, upset stomach, heartburn, loss of appetite, nausea, and vomiting.
Joint pain was reported in more than 15% of participants in one trial of oral N-acetyl cysteine. We don't have enough pregnancy safety data for glycine.
N-acetyl cysteine is rated possibly safe in pregnancy, but supplement use during pregnancy hasn't been well studied. For breastfeeding, there isn't enough reliable safety information for either ingredient, so caution is advised.
Meds to double-check
Major interaction found
If you take nitroglycerin (especially intravenous or patches), blood pressure medications, blood thinners or antiplatelet drugs, the antimalarial chloroquine, or the antipsychotic clozapine, check your specific medications with the tool below before starting Celltrient. The interaction with nitroglycerin is the most serious.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
Celltrient is best suited for people whose doctor or pharmacist has specifically recommended N-acetyl cysteine or glycine for a documented medical reason. If you take heart medications, blood pressure drugs, blood thinners, or clozapine, check your exact medications with us before starting.
Pregnant or breastfeeding? Talk with your doctor or pharmacist first—the safety data aren't complete for either ingredient.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about celltrient, straight from the product label.
| Brand | Nestle Healthcare Nutrition |
|---|---|
| Net contents | 112 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2021 |
| DSLD ID | 252880 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for celltrient by Nestle Healthcare Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Glycine | 600 mg | -- |
| N-Acetyl Cysteine | 600 mg | -- |
Other ingredients: Hydroxypropylmethyl Cellulose, Cellulose Gel, Hydroxypropyl Cellulose, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, treat or prevent any disease.
Precautions
Warning: For adults only.
Do not take this product if you are pregnant or nursing. Consult with your healthcare provider before use if you are taking any medications (especially nitroglycerin) or if you have a medical condition.
Keep out of reach of children.
Use only if safety seal is intact.
Storage
Store in a cool, dry place.
General Statements
Questions/Comments? Call 1-800-849-3016 Monday - Friday 8 am - 8 pm or Saturday 9 am - 5:30 pm ET
Brand IP Statement(s)
All trademarks are owned by Societe des Produits Nestle S.A., Vevey, Switzerland. Copyright 2020 Nestle.
Formulation
Cellular nutrition Cellular protect Supports glutathione production to help protect cells
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested usage: Adults take 2 capsules daily as a dietary supplement.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
celltrient by Nestle Healthcare Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in celltrient by Nestle Healthcare Nutrition
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container56 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Glycine
Interacts with1 drug
Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...
Glycine monograph & interactionsN-Acetyl Cysteine
Interacts with294 drugs
N-acetyl cysteine (NAC) is a supplement form of the amino acid cysteine and a building block for the antioxidant glutathione. It has well-established...
N-Acetyl Cysteine monograph & interactionsOther (inactive) ingredients: Hydroxypropylmethyl Cellulose, Cellulose Gel, Hydroxypropyl Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
celltrient by Nestle Healthcare Nutrition Drug Interactions
HelloPharmacist Interaction Report
Celltrient by Nestle Healthcare Nutrition contains two active ingredients, and one of them—N-acetyl cysteine—has significant interactions with several medication types.
The most serious is with nitroglycerin (a heart medication). Taking N-acetyl cysteine with intravenous or transdermal nitroglycerin can cause severe drops in blood pressure (hypotension) and severe headaches; clinical research confirms this is a real risk.
Read the full breakdown — every affected drug type, severity by severity
N-acetyl cysteine also interacts moderately with blood pressure medications (antihypertensives), blood thinners and antiplatelet drugs (which reduce clotting), the antimalarial drug chloroquine, and activated charcoal (used in some poisonings or overdoses). The glycine in this product has a separate moderate interaction with clozapine, an antipsychotic medication—one small study suggests it may worsen schizophrenia symptoms when added to clozapine therapy.
Although we have interaction data for the two active ingredients in this product, we did not independently verify every specific medication in each category. Altogether, these interactions span 295 individual medications.
Before you start Celltrient, use the medication checker on this page to look up any prescription or over-the-counter drugs you take.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against celltrient?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in celltrient interact with 295 drugs. Click any drug to see the details.
2 of the 2 ingredients in celltrient interact with drugs. Each result below shows which ingredient is responsible. N-Acetyl Cysteine Glycine
NitroglycerinGonitro, Nitro Time, Nitro-Bid, Nitrocine Timecaps, Nitrogard, Nitrogard SR +7 more
How Nitroglycerin interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineNitroglycerin Major
Interaction Summary
N-acetyl cysteine can increase the risk for hypotension and headaches when taken with intravenous or transdermal nitroglycerin.
Read the full N-acetyl Cysteine + Nitroglycerin interactionAbciximabReoPro
How Abciximab interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Abrocitinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Acetazolamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Acetylsalicylic Acid interactionAliskirenTekturna
How Aliskiren interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Aliskiren interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Apixaban interactionAprocitentanTryvio
How Aprocitentan interacts with celltrient — through 1 ingredient. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Aprocitentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in celltrient with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
N-Acetyl Cysteine
Nitroglycerin
N-acetyl cysteine can increase the risk for hypotension and headaches when taken with intravenous or transdermal nitroglycerin.
Clinical research shows that concomitant administration of N-acetyl cysteine and intravenous or transdermal nitroglycerin can cause severe hypotension and intolerable headaches. Furthermore, in vitro research suggests that N-acetyl cysteine increases the anticoagulant activity of nitroglycerin.
Activated Charcoal
N-acetyl cysteine might reduce the effects of activated charcoal, while activated charcoal might reduce the absorption of N-acetyl cysteine.
N-acetyl cysteine appears to reduce the capacity of activated charcoal to adsorb acetaminophen and salicylic acid. Conversely, although clinical research suggests that although activated charcoal can reduce the absorption of N-acetyl cysteine by up to 40%, it does not seem to reduce its clinical effects. Other clinical evidence suggests that activated charcoal does not affect the absorption of N-acetyl cysteine.
Anticoagulant/Antiplatelet Drugs
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Clinical research suggests that intravenous N-acetyl cysteine decreases prothrombin time, prolongs coagulation time, decreases platelet aggregation, and increases blood loss in surgical patients. Furthermore, in vitro research suggests that N-acetyl cysteine increases the anticoagulant activity of nitroglycerin.
Antihypertensive Drugs
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that N-acetyl cysteine potentiates the hypotensive effects of the angiotensin-converting enzyme inhibitors (ACEIs) captopril and enalaprilat. Theoretically, combining N-acetyl cysteine with other antihypertensive drugs might increase the risk of hypotension.
Chloroquine (Aralen)
Theoretically, N-acetyl cysteine might interfere with the antimalarial effects of chloroquine.
Animal research suggests that N-acetyl cysteine might reduce the antimalarial effects of chloroquine by increasing cellular levels of glutathione.
Glycine
Clozapine (Clozaril)
Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.
Brand information
Manufacturer and brand details for celltrient, from the product label.
Nestle Healthcare Nutrition
See all Nestle Healthcare Nutrition products- Name
- Nestle HealthCare Nutrition, Inc.
- City
- Bridgewater
- State
- NJ
- ZipCode
- 08807
- Phone Number
- 1-800-849-3016
celltrient by Nestle Healthcare Nutrition: Common Questions
Does celltrient by Nestle Healthcare Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does this product really have 295 interactions?
What is N-acetyl cysteine used for?
Is glycine safe for ADHD or other conditions?
What are the most common side effects?
Can I take this if I'm pregnant or breastfeeding?
Why does this product interact with so many medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if celltrient is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind celltrient’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Glycine
Interacts with 1 drugGlycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep quality, where early research is promisin...
Read the full Glycine monograph → Herb & supplement monographN-acetyl Cysteine (nac)
Interacts with 294 drugsN-acetyl cysteine (NAC) is a supplement form of the amino acid cysteine and a building block for the antioxidant glutathione. It has well-established prescription uses for acetaminophen over...
Read the full N-acetyl Cysteine (nac) monograph →Sources & How We Checked
celltrient's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 91 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Glycine 5 references
- Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
- Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
- Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
- Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
- Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed
N-acetyl Cysteine (nac) 86 references
- Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
- Jepsen S, Hansen AB. The influence of N-acetylcysteine on the measurement of prothrombin time and activated partial thromboplastin time in healthy subjects. Scand J Clin Lab Invest 1994;54:543-7. PubMed
- van Zandwijk N, Dalesio O, Pastorino U, et al. EUROSCAN, a randomized trial of vitamin A and N-acetylcysteine in patients with head and neck cancer or lung cancer. For the European Organization for Research and Treatment of Cancer Head and Neck and Lung C DOI
- Horowitz RS, Dart RC, Jarvie DR, et al. Placental transfer of N-acetylcysteine following human maternal acetaminophen toxicity. J Toxicol Clin Toxicol 1997;35:447-51.
- Bailey B, McGuigan MA. Management of anaphylactoid reactions to intravenous N-acetylcysteine. Ann Emerg Med 1998;31:710-5. PubMed
- Spiller HA, Krenzelok EP, Grande GA, et al. A prospective evaluation of the effect of activated charcoal before oral N-acetylcysteine in acetaminophen overdose. Ann Emerg Med 1994;23:519-23. PubMed
- Ardissino D, Merlini PA, Savonitto S, et al. Effect of transdermal nitroglycerin or N-acetylcysteine, or both, in the long-term treatment of unstable angina pectoris. J Am Coll Cardiol 1997;29:941-7. PubMed
- Horowitz JD, Henry CA, Syrjanen ML, et al. Nitroglycerine/N-acetylcysteine in the management of unstable angina pectoris. Eur Heart J 1988;9:95-100. PubMed
- Louwerse ES, Weverling GJ, Bossuyt PM, et al. Randomized, double-blind, controlled trial of acetylcysteine in amyotrophic lateral sclerosis. Arch Neurol 1995;52:559-64. PubMed
- Wiklund O, Fager G, Andersson A, et al. N-acetylcysteine treatment lowers plasma homocysteine but not serum lipoprotein(a) levels. Atherosclerosis 1996;119:99-106. PubMed
- De Flora S, Grassi C, Carati L. Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment. Eur Respir J 1997;10:1535-41. PubMed
- Iversen HK. N-acetylcysteine enhances nitroglycerin-induced headache and cranial arterial responses. Clin Pharmacol Ther 1992;52:125-33. PubMed
- Behr J, Maier K, Degenkolb B, et al. Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintenance immunosuppression. Am J Respir Crit Care Med 1997;156:1897-901.
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