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Dietary supplement

Centrum Calm & Reset Cherry Flavor Ingredients & Drug Interactions

by Centrum

Centrum Calm & Reset Cherry Flavor label
See full label image
Gummy Or Jelly Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Centrum Calm & Reset Cherry Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Centrum Calm & Reset Cherry Flavor is a dietary supplement by Centrum with 3 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 1,377 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are KSM66 Ashwagandha root extract, Vitamin B6, Vitamin B12. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Centrum Calm & Reset Cherry Flavor by Centrum

Ask about any prescription or over-the-counter medication and we check it for interactions with Centrum Calm & Reset Cherry Flavor by Centrum — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Centrum Calm & Reset Cherry Flavor by Centrum

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Centrum Calm & Reset contains three active ingredients. Vitamin B6 and vitamin B12 are B vitamins your body needs for nerve and blood cell health.

KSM66 Ashwagandha root extract is a standardized form of ashwagandha, an herb traditionally used to support relaxation and stress response. The product also contains inactive ingredients like tapioca syrup, sugar, and water to form the gummy.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: calm mind and reduce stress support.
  • We looked for evidence on: Anxiety, Generalized anxiety disorder (GAD), Fatigue, Cognitive function, Stress management, Mental clarity — and 2 related terms.
  • The strongest evidence on file: Ashwagandha is rated "Possibly Effective" for Anxiety (Natural Medicines).
  • Also on file: Ashwagandha is rated "Possibly Effective" for Generalized anxiety disorder (GAD), Stress.
  • Also on file: Vitamin B12 is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Cognitive function, Fatigue.

The evidence for this product's purpose — calm and reset — rests mainly on ashwagandha. The data shows ashwagandha is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder; for bipolar disorder, the evidence is too thin to rate.

Vitamin B6 and B12 are effective for their respective deficiencies and certain rare conditions, but the product facts we hold don't establish them as calming ingredients. If you're looking for help with anxiety or sleep, ashwagandha has some support — just know it's "possibly effective," meaning the evidence is suggestive but not definitive.

The evidence, ingredient by ingredient Vitamin B6 Vitamin B12 Ashwagandha

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is well tolerated in doses under 100 mg daily but can harm your nerves (sensory neuropathy) at high doses over time or with very high total doses. Most common side effects are mild — headache, nausea, stomach pain.

Vitamin B12 is generally very safe with no upper limit; excess is removed in your urine. Ashwagandha is well tolerated short-term in healthy adults, though long-term safety data are limited.

Rare serious side effects include liver damage and hepatitis. Common side effects with typical doses are uncommon but can include diarrhea, nausea, and drowsiness.

For pregnancy: Vitamin B6 ratings are mixed (Likely Safe and Possibly Unsafe), so talk with your doctor before using it in pregnancy. Vitamin B12 is Likely Safe in pregnancy.

Ashwagandha is Likely Unsafe in pregnancy — the traditional concern is miscarriage risk. For breastfeeding: Vitamin B6 and B12 are considered Likely Safe at recommended amounts.

Ashwagandha has insufficient safety data, so avoid it while nursing.

Side effects, ingredient by ingredient Vitamin B6 Vitamin B12 Ashwagandha

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Vitamin B12, Vitamin B6, Ashwagandha.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; Parkinson's medications.
  • For scale: 1,378 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check your medications if you take CNS depressants, benzodiazepines, or sedatives (ashwagandha may increase drowsiness); blood pressure medications (both B6 and ashwagandha may lower it further); diabetes medications (ashwagandha may increase low blood sugar risk); seizure medications like phenobarbital or phenytoin (B6 may reduce their effectiveness); thyroid hormones (ashwagandha may amplify effects); immunosuppressants (ashwagandha may weaken them); or metformin (B12 may help offset B12 loss from the drug). If you're on amiodarone, high-dose B6 may worsen sun sensitivity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is built around ashwagandha for anxiety and stress support, backed by possibly effective evidence. If you're on blood pressure meds, diabetes meds, seizure meds, benzodiazepines, sedatives, thyroid hormones, or medications that suppress your immune system, talk with your pharmacist before starting — the interactions could affect how well your drugs work.

Pregnant or breastfeeding? Check with your doctor first, especially about the ashwagandha.

For everyone else in good health, run your full medication list through the checker on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Centrum Calm & Reset Cherry Flavor, straight from the product label.

Brand Centrum
Barcode (UPC) 305734987505
Net contents 50 Gummy(ies)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 251347
Product type Botanical With Nutrients
Supplement form Gummy Or Jelly
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Centrum Calm & Reset Cherry Flavor by Centrum, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gummy(ies)
Maximum serving Sizes:
2 Gummy(ies)
Servings per container
25
UPC/BARCODE
305734987505
IngredientAmount% DV
Calories20 Calorie(s)--
Total Carbohydrates5 Gram(s)2%
Vitamin B61.7 Gram(s)100%
Added Sugars4 Gram(s)8%
Total Sugars4 Gram(s)--
Vitamin B122.4 mcg100%
KSM66 Ashwagandha root extract250 mg--

Other ingredients: Tapioca Syrup, Sugar, Water, Contains less than 2% of

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

New! gsk

Formulation

Calm & ready for your day ahead

Purposely crafted to supoport your mind & body

Proudly manufactured in a GMP facility.

Vegetarian.

No gluten, dairy, soy, or nuts.

Due to use of plant-based colors, gummy appearance may darken over time. This does not alter the product potency.

Formula

Clinically studied organic ashwagandha Cherry flavor with other natural flavors

Clinically-studied organic KSM-66 ashwagandha is a natural adaptogen that gently helps de-stress. Vitamins B6 & B12 support normal brain and nervous system function.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: Adults: Take two (2) gummies daily. Do not exceed suggested use.

Precautions

Not formulated for use in children.

As with any supplement, if you are taking medication, consult your doctor before use. Do not consume if pregnant or nursing.

Keep out of reach of children.

If taking other supplements, read label, since supplements, may contain the same ingredient.

Bottle sealed with printed foil under cap. Do not use if foil is torn.

Storage

Store at room temperature. Keep bottle tightly closed. Protect from moisture.

Brand IP Statement(s)

Trademarks owned or licensed by GSK. 2020 GSK or licensor.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Centrum Calm & Reset Cherry Flavor by Centrum label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Centrum Calm & Reset Cherry Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Centrum Calm & Reset Cherry Flavor by Centrum

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B6

Interacts with
210 drugs
1.7 Gram(s) per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Vitamin B12

Interacts with
20 drugs
2.4 mcg per serving Form: Methylcobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

KSM66 Ashwagandha root extract

Interacts with
1,372 drugs
250 mg per serving

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evid...

KSM66 Ashwagandha root extract monograph & interactions

Other (inactive) ingredients: Tapioca Syrup, Sugar, Water, Contains less than 2% of. These complete the product’s ingredient list but are not active constituents.

Interaction report

Centrum Calm & Reset Cherry Flavor by Centrum Drug Interactions

Want to check YOUR meds against Centrum Calm & Reset Cherry Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,377Drugs
916 Moderate 461 Minor

Ingredients driving the most interactions

KSM66 Ashwagandha root extract 1,372
Vitamin B6 210
Vitamin B12 20

Individual Drug Interactions

The ingredients in Centrum Calm & Reset Cherry Flavor interact with 1,377 drugs. Click any drug to see the details.

3 of the 3 ingredients in Centrum Calm & Reset Cherry Flavor interact with drugs. Each result below shows which ingredient is responsible. KSM66 Ashwagandha root extract Vitamin B6 Vitamin B12

Each ingredient & the kinds of drugs it affects

For each ingredient in Centrum Calm & Reset Cherry Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

KSM66 Ashwagandha root extract10 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C
KSM66 Ashwagandha root extract full monograph & interactions

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Centrum Calm & Reset Cherry Flavor, from the product label.

Centrum

Name
GSK Consumer Healthcare
City
Warren
State
NJ
ZipCode
07059
Phone Number
1-877-236-8786
Web Address
www.centrum.com
Pharmacist Counseling Corner

Centrum Calm & Reset Cherry Flavor by Centrum: Common Questions

Does Centrum Calm & Reset Cherry Flavor by Centrum interact with any medications?
Yes. Based on its ingredients, Centrum Calm & Reset Cherry Flavor has a known interaction with 1,377 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Centrum Calm & Reset Cherry Flavor contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on blood pressure medication?
Both vitamin B6 and ashwagandha can theoretically lower blood pressure on their own, so taking them with blood pressure meds might drop your blood pressure more than intended. Check with your pharmacist before starting — they may want to monitor you or adjust your dosing.
Is ashwagandha safe to take long-term?
Ashwagandha is generally well tolerated short-term in healthy adults, but long-term safety data are limited. Rare serious cases of liver damage have been reported. For ongoing use, talk with your doctor or pharmacist to decide if it's right for you and how often to check in.
Will this help with anxiety and sleep?
Ashwagandha is possibly effective for anxiety, stress, and insomnia — meaning the evidence is suggestive but not definitive. It may help some people, but results vary. Give it a fair trial and let your doctor know if it's working for you.
Can I take this while pregnant or breastfeeding?
Ashwagandha is considered likely unsafe in pregnancy due to traditional concerns about miscarriage — avoid it. For breastfeeding, there isn't enough safety data, so skip it while nursing. Vitamin B12 is fine in both, but talk with your doctor about vitamin B6 in pregnancy, as the evidence is mixed.
What are the most common side effects?
With typical doses, ashwagandha's most common side effects — like nausea, diarrhea, or drowsiness — don't happen often. Vitamin B6 can cause headache, nausea, or stomach pain at normal doses. Vitamin B12 is very well tolerated.
Does this have any fillers?
Yes. The inactive ingredients include tapioca syrup, sugar, and water to make the gummy. If you need a filler-free product, this isn't it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Centrum Calm & Reset Cherry Flavor label
Go deeper

The Full Monographs Behind Centrum Calm & Reset Cherry Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

Ashwagandha

Interacts with 1,372 drugs

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...

Read the full Ashwagandha monograph →
Sources

Sources & How We Checked

Centrum Calm & Reset Cherry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 94 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
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Ashwagandha 32 references
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