Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

ChagaMax Ingredients & Drug Interactions

by North American Herb & Spice

ChagaMax label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking ChagaMax against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

ChagaMax is a dietary supplement by North American Herb & Spice with 5 active ingredients. Its ingredients are commonly taken for immune support, antioxidant support, general wellness/tonic.Based on those ingredients, 402 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are wild, raw Chaga Mushroom powder, wild, organic desiccated Oregano Oil, wild, raw White Birch bark powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against ChagaMax by North American Herb & Spice

Ask about any prescription or over-the-counter medication and we check it for interactions with ChagaMax by North American Herb & Spice — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of ChagaMax by North American Herb & Spice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (400 mg) without saying how much of each component you get.

ChagaMax contains five active ingredients. You've got two forms of wild chaga mushroom powder—raw chaga and Black Siberian chaga—along with two types of oregano (desiccated oregano oil and Mediterranean oregano), plus wild white birch bark powder.

The product uses a proprietary blend formula, so you won't see the exact dose of each ingredient on the label. There are no inactive fillers or other ingredients listed.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This product is marketed for general wellness, not a specific health condition, so there's no single claim to grade against clinical evidence.

Why this rating?
  • The label markets general wellness (“Antioxidant support and general wellness”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence supporting ChagaMax's ingredients isn't established in the data we hold. Both chaga forms show insufficient reliable evidence for cardiovascular disease, diabetes, and COVID-19.

The oregano ingredients—both the oil and Mediterranean variety—have insufficient evidence for acne, bronchitis, asthma, headache, and upper respiratory tract infections. Birch bark powder also shows insufficient evidence for joint pain, hair loss (alopecia), and dandruff.

This means the science doesn't yet support these uses, not that they don't work—just that the studies aren't there to prove it.

The evidence, ingredient by ingredient Chaga Oregano Birch

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chaga is generally used in foods and teas, but human safety data are limited. There have been rare reports of kidney problems and kidney damage (nephropathy) tied to very high chaga intake due to its oxalate content—a compound that can accumulate in the kidneys.

The oregano forms are well tolerated in food amounts, but as concentrated supplement doses, they're less studied. At normal food levels, side effects are uncommon; the most common is mild stomach upset.

Rare but serious allergic reactions, including anaphylaxis, have been reported in people sensitive to the oregano family. Birch bark can trigger allergic reactions in those sensitive to birch pollen, and allergic contact dermatitis has been reported with topical use.

During pregnancy, chaga safety data aren't available—best to avoid it. Oregano in medicinal or supplement amounts is possibly unsafe in pregnancy; food amounts are likely okay.

Birch supplements lack safety data and are best avoided in pregnancy. For breastfeeding, chaga and birch safety hasn't been established, so stick to food amounts or talk with your doctor.

Oregano supplement safety while breastfeeding is uncertain—food amounts are safer.

Side effects, ingredient by ingredient Chaga Oregano Birch

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Birch, Oregano, Chaga.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 402 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take ChagaMax, double-check with your pharmacist if you're on blood thinners or antiplatelet drugs like warfarin or clopidogrel—both chaga and oregano may theoretically boost bleeding risk. If you take diabetes medication, the chaga and oregano may lower your blood sugar further.

If you're on immunosuppressants (used after transplants or for autoimmune disease), chaga might interfere. Anyone on diuretics (water pills) should check with their pharmacist about the birch component.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Consider ChagaMax if you're drawn to mushroom and herbal blends and have no blood thinners, diabetes, or immunosuppressive medications in your routine. Be especially careful if you take anticoagulants, diabetes drugs, or immune-suppressing therapy—these need a pharmacist check first.

If you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting; the safety data aren't solid. Run your medications through our checker to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ChagaMax, straight from the product label.

Brand North American Herb & Spice
Barcode (UPC) 635824006084
Net contents 12 Vegi Cap(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 269236
Product type Botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ChagaMax by North American Herb & Spice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
12
UPC/BARCODE
635824006084
IngredientAmount% DV
Proprietary Blend400 mg--
wild, raw Chaga Mushroom powder0 NP--
wild, organic desiccated Oregano Oil0 NP--
wild, organic Mediterranean Oregano0 NP--
wild Black Siberian Chaga powder0 NP--
wild, raw White Birch bark powder0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formulation

Wild Source 100% Raw High Orac

Testing shows that the superoxide radical-quenching power of ChagaMax is extremely high. The wild oregano greatly fortifies the chaga.

Formula

Wild Chaga & oregano Plus wild birch bark 3,946 ORAC units per pack

ChagaMax is the power of wild, raw chaga mushroom fortified with wild, raw birch bark and handpicked wild oregano. This combination creates immense synergy and potency. These wild, powerful foods are top sources of key substances needed for human health: plant sterols and antioxidants. Chaga is the richest source of the all-important enzyme superoxide dismutase (SOD), plus it is a natural source of beta glucan and B vitamins.

General Statements

Convenience Pak 12 (400 mg) Vegi Caps

Suggested/Recommended/Usage/Directions

Directions: Take one or more capsules daily with or without meals.

Take ChagaMax capsules daily, and feel the difference.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

ChagaMax by North American Herb & Spice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

ChagaMax label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in ChagaMax by North American Herb & Spice

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container12 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Interaction report

ChagaMax by North American Herb & Spice Drug Interactions

Want to check YOUR meds against ChagaMax?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
402Drugs
327 Moderate 75 Minor

Ingredients driving the most interactions

wild, raw Chaga Mushroom powder 327
wild, organic desiccated Oregano Oil 208
wild, raw White Birch bark powder 75

Individual Drug Interactions

The ingredients in ChagaMax interact with 402 drugs. Click any drug to see the details.

3 of the 5 ingredients in ChagaMax interact with drugs. Each result below shows which ingredient is responsible. wild, raw Chaga Mushroom powder wild, organic desiccated Oregano Oil wild, raw White Birch bark powder

Each ingredient & the kinds of drugs it affects

For each ingredient in ChagaMax with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

wild, raw Chaga Mushroom powder3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.

Likelihood Possible Evidence D
wild, raw Chaga Mushroom powder full monograph & interactions

wild, organic desiccated Oregano Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
wild, organic desiccated Oregano Oil full monograph & interactions

wild, raw White Birch bark powder1 drug type · 75 drugs

Diuretic Drugs

Theoretically, birch might interfere with diuretic therapy.

Likelihood Possible Evidence D
wild, raw White Birch bark powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for ChagaMax, from the product label.

North American Herb & Spice

See all North American Herb & Spice products
Name
North American Herb & Spice
Street Address
13900 W. Polo Trail Drive
City
Lake Forest
State
IL
ZipCode
60045
Phone Number
1-847-473-4700
Web Address
www.oreganol.com
Pharmacist Counseling Corner

ChagaMax by North American Herb & Spice: Common Questions

Does ChagaMax by North American Herb & Spice interact with any medications?
Yes. Based on its ingredients, ChagaMax has a known interaction with 402 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ChagaMax contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is chaga, and why is it in this product?
Chaga is a type of mushroom that grows on birch trees and has been used in foods and teas. This product contains two forms of wild chaga powder. The evidence for what it does isn't yet established in the data we hold, so we don't have reliable claims about its benefits.
Can I take this if I'm pregnant?
No. Chaga, oregano in medicinal amounts, and birch all lack enough safety information in pregnancy for us to recommend them. Food amounts of oregano are likely fine, but this is a supplement, not a food seasoning. Talk with your doctor or pharmacist about whether it's right for you.
Is oregano oil safe to take every day?
Oregano in regular food amounts is well tolerated, but as a concentrated supplement, human safety data are limited. The most common side effect is stomach upset. Rare but serious allergic reactions have been reported in sensitive people. If you have a history of allergies to plants in the mint family (like thyme), mention it to your pharmacist before starting.
I'm on a blood thinner. Can I take this?
Not without checking first. Both the chaga and oregano in ChagaMax may theoretically increase bleeding risk when combined with blood thinners like warfarin, though this hasn't been proven in humans. Run this product through our medication checker or call your pharmacist before starting.
What does birch bark do in this product?
Birch bark powder is included in the blend, but the evidence for what it does isn't established in the data we hold. It may cause allergic reactions in people sensitive to birch pollen.
Are there any inactive fillers or additives?
No inactive ingredients are listed for ChagaMax. The product contains only the five active botanical ingredients in a proprietary blend—no fillers, binders, or other additives are noted.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ChagaMax is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ChagaMax label
Go deeper

The Full Monographs Behind ChagaMax’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chaga

Interacts with 327 drugs

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...

Read the full Chaga monograph → Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph → Herb & supplement monograph

Birch

Interacts with 75 drugs

Birch is a tree whose leaves, bark, and sap are used in traditional remedies, most often as a mild diuretic or for joint and urinary complaints. Solid human evidence is limited, and birch is...

Read the full Birch monograph →
Sources

Sources & How We Checked

ChagaMax's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 25 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chaga 9 references
  1. Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
  2. Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
  3. Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
  4. Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
  5. Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
  6. Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
  7. Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
  8. Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
  9. Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed

See these in context on the Chaga monograph →

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Birch 4 references
  1. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  2. Lahti, A. and Hannuksela, M. Immediate contact allergy to birch leaves and sap. Contact Dermatitis 1980;6(7):464-465. PubMed
  3. Allam JP, Wuestenberg E, Wolf H, et al. Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: a pilot study. J Allergy Clin Immunol. 2014;133(6):1757-9.e3. PubMed
  4. Meyer-Hoffert U, Brasch J. Allergic contact dermatitis caused by betulin-containing triterpene extract from the outer bark of birch (Betula alba). Contact Dermatitis. 2013;68(6):382-3.

See these in context on the Birch monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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