Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Chamomile Flowers Extract Ingredients & Drug Interactions

by Oregon's Wild Harvest

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Chamomile Flowers Extract is a dietary supplement by Oregon's Wild Harvest with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep and relaxation, digestive upset.Based on those ingredients, 960 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are German Chamomile. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Chamomile Flowers Extract by Oregon's Wild Harvest

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: German chamomile, an herbal extract in liquid form. The inactive ingredients are alcohol and distilled water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient German Chamomile product and its label doesn't state a use — see German Chamomile's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for German chamomile's effectiveness for any condition is insufficient in the data we hold. It has been studied for hay fever, anxiety, ADHD, sexual dysfunction, and cancer-related loss of appetite, but reliable evidence supporting its use for these purposes is not established.

The evidence, ingredient by ingredient German Chamomile

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

German chamomile is generally well tolerated in most adults, but it can cause allergic reactions in people who are sensitive to ragweed and related plants—some cases of severe hypersensitivity reactions and anaphylaxis have been reported. Topically, it may cause allergic dermatitis and eczema.

When used as an oral rinse, some people have reported nausea and burning in the mouth. During pregnancy, safety data are not sufficient, so it's best avoided unless your doctor approves.

While breastfeeding, limited safety data exist; check with your doctor or pharmacist before using.

Side effects, ingredient by ingredient German Chamomile

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — German Chamomile.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 961 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take warfarin or another blood thinner (risk of increased bleeding), CNS depressants like sedating medications (risk of added drowsiness), oral contraceptives or estrogen therapy (risk of reduced effectiveness), tamoxifen (risk of reduced cancer-drug effectiveness), or any medication broken down by your liver, such as certain heart, diabetes, or psychiatric drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Chamomile extract is generally well tolerated in most people, but its interactions with blood thinners, sedating medications, hormonal drugs, and liver-metabolized medications are a real concern. If you take any prescription medication—especially warfarin, sleep aids, birth control, hormone therapy, or tamoxifen—check with your doctor or pharmacist before adding this product.

People with ragweed allergies should avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chamomile Flowers Extract, straight from the product label.

Brand Oregon's Wild Harvest
Barcode (UPC) 701695001944
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 307172
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chamomile Flowers Extract by Oregon's Wild Harvest, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
30
UPC/BARCODE
701695001944
IngredientAmount% DV
German Chamomile250 mg--

Other ingredients: Alcohol, Water, Distilled

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Organic to our roots Certified organic since 1994, our regenerative practices heal the planet while providing potent herbs today and for future generations.

Formulation

Free from: gluten, dairy and soy allergens.

Organic USDA Organic

Non GMO GF Gluten Free

Extract

Certified Organic by Oregon Tilth Oregon Tilth Certified Organic (OTCO)

Precautions

Caution: keep out of reach of children.

Do not take if pregnant or nursing. If taking medication consult a healthcare professional before use.

Discontinue use if unusual symptoms occur.

Do not exceed recommended dose.

Brand IP Statement(s)

Oregon's Wild Harvest Herbal Supplement Since 1994

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic

Oregon Tilth Certified Organic (OTCO)

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 mL three times daily in warm water or juice or as directed by your healthcare professional. 1 mL = approx. 40 drops.

Shake well.

Storage

Store upright in a cool, dry place.

See for yourself

Chamomile Flowers Extract by Oregon's Wild Harvest label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Chamomile Flowers Extract by Oregon's Wild Harvest

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

German Chamomile

Interacts with
960 drugs
250 mg per serving

German chamomile is a widely used herbal remedy taken mainly as a tea for calming, sleep, and digestive complaints. Early research suggests possible b...

German Chamomile monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Distilled. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chamomile Flowers Extract by Oregon's Wild Harvest Drug Interactions

Want to check YOUR meds against Chamomile Flowers Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
960Drugs
925 Moderate 35 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Chamomile Flowers Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

German Chamomile9 drug types · 960 drugs

Cns Depressants

Theoretically, German chamomile might have additive effects when used with CNS depressants.
German chamomile has mild sedative effects. Theoretically, concomitant use with drugs with sedative properties can cause additive effects and side effects.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, large amounts of German chamomile might reduce the effectiveness of oral contraceptives.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, concomitant use of large amounts of German chamomile might interfere with contraceptive drugs through competition for estrogen receptors.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2C9. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2C9 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2D6. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2D6 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP3A4. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP3A4 in patients taking German chamomile.

Likelihood Possible Evidence D
Estrogens

Theoretically, large amounts of German chamomile might reduce the effectiveness of estrogens.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, large amounts of German chamomile might interfere with hormone replacement therapy through competition for estrogen receptors.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, large amounts of German chamomile might interfere with the activity of tamoxifen.
In vitro, German chamomile has demonstrated antiestrogenic activity.

Likelihood Possible Evidence D
Warfarin (Coumadin)

German chamomile might increase the effects of warfarin and increase the risk of bleeding.
In one case, a 70-year-old female taking warfarin developed retroperitoneal hematoma and bilateral recti muscle bleeding along with an INR of 7.9 following ingestion of German chamomile tea 4-5 cups daily and use of a topical chamomile-based lotion applied 4-5 times daily.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
In vitro and animal research shows that German chamomile might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP1A2 in patients taking German chamomile.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Chamomile Flowers Extract, from the product label.

Oregon's Wild Harvest

See all Oregon's Wild Harvest products
Name
Oregon's Wild Harvest
City
Redmond
State
OR
ZipCode
97756
Phone Number
800-316-6869
Web Address
oregonswildharvest.com
Pharmacist Counseling Corner

Chamomile Flowers Extract by Oregon's Wild Harvest: Common Questions

Does Chamomile Flowers Extract by Oregon's Wild Harvest interact with any medications?
Yes. Based on its ingredients, Chamomile Flowers Extract has a known interaction with 960 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chamomile Flowers Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on birth control or hormone replacement therapy?
Theoretically, large amounts of German chamomile may interfere with how your birth control or hormone therapy works through an antiestrogenic effect. This isn't confirmed in humans yet, but it's a real concern. Talk with your doctor or pharmacist before using this product if you rely on hormonal contraception or hormone replacement.
What if I'm allergic to ragweed?
You should avoid this product. German chamomile can trigger allergic reactions in people sensitive to ragweed and related plants, including severe reactions in rare cases.
Is this safe during pregnancy?
There isn't enough reliable safety information, so it's best avoided during pregnancy unless your doctor approves. Talk with your doctor before using it.
Can I use this while breastfeeding?
Limited safety data exist for breastfeeding. Check with your doctor or pharmacist before using this product while nursing.
Does this actually work for anxiety or sleep?
The evidence we hold is insufficient to say whether German chamomile reliably helps anxiety or other conditions. While it has mild sedative properties, we don't have established proof of effectiveness for these uses.
What side effects might I notice?
Most people tolerate it well, but allergic reactions can occur—including sneezing, itchy eyes, or in rare cases severe hypersensitivity. When used as an oral rinse, some people report nausea or mouth burning. If you have a ragweed allergy, the risk is higher.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chamomile Flowers Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chamomile Flowers Extract label
Sources

Sources & How We Checked

Chamomile Flowers Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

German Chamomile 15 references
  1. Subiza J, Subiza JL, Hinojosa M, et al. Anaphylactic reaction after the ingestion of chamomile tea; a study of cross-reactivity with other composite pollens. J Allergy Clin Immunol 1989;84:353-8. PubMed
  2. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  3. Viola H, Wasowski C, Levi de Stein M, et al. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med 1995;61:213-6.
  4. van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1982;8:143. PubMed
  5. van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1987;16:50-1. PubMed
  6. Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
  7. Avallone R, Zanoli P, Puia G, et al. Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla. Biochem Pharmacol 2000;59:1387-94. PubMed
  8. Kassi E, Papoutsi Z, Fokialakis N, et al. Greek plant extracts exhibit selective estrogen receptor modulator (SERM)-like properties. J Agric Food Chem 2004;52:6956-61. PubMed
  9. Maliakal PP, Wanwimolruk S. Effect of herbal teas on hepatic drug metabolizing enzymes in rats. J Pharm Pharmacol 2001;53:1323-9. PubMed
  10. Segal R, Pilote L. Warfarin interaction with Matricaria chamomilla. CMAJ 2006;174:1281-2. PubMed
  11. Loggia RD, Traversa U, Scarcia V, et al. Depressive effects of Chamomilla recutita (L.) Rausch, tubular flowers, on central nervous system in mice. Pharmacol Res Commun 1982;14(2):153-162. PubMed
  12. Ganzera M, Schneider P, Stuppner H. Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes. Life Sci 2006;78(8):856-861. PubMed
  13. Benito P, Rodríguez-Perez R, García F, Juste S, Moneo I, Caballero ML. Occupational allergic rhinoconjunctivitis induced by Matricaria chamomilla with tolerance of chamomile tea. J Investig Allergol Clin Immunol. 2014;24(5):369-70. No abstract available.
  14. Braga FT, Santos AC, Bueno PC, et al. Use of Chamomilla recutita in the prevention and treatment of oral mucositis in patients undergoing hematopoietic stem cell transplantation: a randomized, controlled, phase II clinical trial. Cancer Nurs 2015;38(4):32 PubMed
  15. Sarris J, Ravindran A, Yatham LN, et al. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety T

See these in context on the German Chamomile monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring