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Dietary supplement

Kids Tranquil Child Alcohol-Free Extract Ingredients & Drug Interactions

by Oregon's Wild Harvest

Kids Tranquil Child Alcohol-Free Extract label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kids Tranquil Child Alcohol-Free Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kids Tranquil Child Alcohol-Free Extract is a dietary supplement by Oregon's Wild Harvest with 4 active ingredients. Its ingredients are commonly taken for anxiety and stress, sleep and relaxation, digestive upset.Based on those ingredients, 994 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chamomile, Dry, Passionflower, Dry, Peppermint, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Kids Tranquil Child Alcohol-Free Extract by Oregon's Wild Harvest

Ask about any prescription or over-the-counter medication and we check it for interactions with Kids Tranquil Child Alcohol-Free Extract by Oregon's Wild Harvest — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Kids Tranquil Child Alcohol-Free Extract by Oregon's Wild Harvest

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Dry Organic Proprietary Blend” is a proprietary blend — the label gives one combined amount (250 mg) without saying how much of each component you get.

This liquid extract contains four active herbal ingredients: chamomile, passionflower, catnip, and peppermint, all in dried form within a proprietary blend. The product also includes glycerin and citrus extract as inactive ingredients to preserve the liquid and add flavor.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Calming and relaxation support for children.
  • We looked for evidence on: Anxiety, Stress, Insomnia, Generalized anxiety disorder (GAD), Adjustment disorders, Nervousness — and 3 related terms.
  • The strongest evidence on file: Passion Flower is rated "Possibly Effective" for Pre-procedural anxiety (Natural Medicines).
  • Also on file: Passion Flower is rated "Possibly Effective" for Insomnia.
  • Also on file: Peppermint is rated "Insufficient Reliable Evidence To Rate" for Pre-procedural anxiety, Insomnia, Stress, Postoperative sleep disturbance.

The evidence is limited for most uses in kids. Peppermint has the strongest data—it's likely effective for irritable bowel syndrome and possibly effective for indigestion, nausea from chemotherapy, and spasm during medical procedures.

Passionflower is possibly effective for insomnia and anxiety before medical procedures. Chamomile, catnip, and their combinations lack reliable evidence for the conditions listed (anxiety, ADHD, hay fever, and others).

If you're considering this for a specific concern, talk with your child's doctor or pharmacist about what the science actually supports.

The evidence, ingredient by ingredient German Chamomile Passion Flower Catnip Peppermint

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chamomile, passionflower, catnip, and peppermint are all generally well tolerated when used in typical amounts, but each carries cautions. Chamomile may trigger allergic reactions in children sensitive to ragweed or related plants, ranging from mild (itching, watery eyes) to severe (anaphylaxis).

Passionflower commonly causes drowsiness, dizziness, and confusion. Catnip may cause headache, vomiting, or stomachache at high doses.

Peppermint can cause abdominal pain, heartburn, and anal burning, and rarely has caused severe allergic reactions. Pregnancy data are not applicable here, but if you're breastfeeding and considering giving this to your child, there isn't enough safety information on passionflower or catnip in breast milk—check with your pediatrician or pharmacist first.

Side effects, ingredient by ingredient German Chamomile Passion Flower Catnip Peppermint

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Peppermint, Catnip, Passion Flower, German Chamomile.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; lithium.
  • For scale: 995 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before giving this to your child, check with your pharmacist or doctor if they take any blood thinners like warfarin, CNS depressants or sedatives (including some pain, anxiety, or sleep medications), any drugs metabolized by the liver enzymes CYP2D6, CYP2C9, CYP2C19, or CYP3A4 (a very common group), cyclosporine, birth control, hormone therapy, or tamoxifen. The interaction data we hold covers three of the four ingredients; we could not check the proprietary blend itself.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a herbal blend meant to calm children, but the evidence that it actually works for anxiety or ADHD is not established in our data. The bigger concern is that three of its four ingredients interact with a large number of medications—including blood thinners, sedatives, and drugs your child's liver processes—and some interactions are serious.

Before you start this product, have your child's doctor or pharmacist check it against any prescriptions or over-the-counter medications your child takes.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kids Tranquil Child Alcohol-Free Extract, straight from the product label.

Brand Oregon's Wild Harvest
Barcode (UPC) 706195003177
Net contents 1 Fluid Ounce(s); 30 Milliliter(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 307201
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Women (not pregnant or lactating), Organic, Gluten Free, Dairy Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kids Tranquil Child Alcohol-Free Extract by Oregon's Wild Harvest, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
30
UPC/BARCODE
706195003177
IngredientAmount% DV
Dry Organic Proprietary Blend250 mg--
Chamomile, Dry0 NP--
Passionflower, Dry0 NP--
Catnip, Dry0 NP--
Peppermint, Dry0 NP--

Other ingredients: Glycerin, Citrus Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Organic to our roots

Suggested/Recommended/Usage/Directions

Suggested use: Take 1 mL up to three times daily in warm water or juice or as directed by your healthcare professional. 1 mL = approx. 30 drops. Formulated for children 2-12 years.

Shake well.

Precautions

Not for use in infants. Caution: Keep out of reach of children.

Do not exceed recommended dose. Discontinue use if unusual symptoms occur.

Do not take if pregnant or nursing. If taking medication consult a healthcare professional before use.

Formulation

Free from: Gluten, dairy and soy allergens. And no artificial ingredients.

This product includes dry plant material which contains beneficial chlorophyll. These naturally occurring oils may adhere to bottle and dropper.

Non-GMO GF

USDA Organic

Herbs extracted in alcohol, alcohol removed.

Certified Organic by Oregon Tilth OTCO

Brand IP Statement(s)

Oregon's Wild Harvest Herbal Supplement Since 1994

Seals/Symbols

USDA Organic

Storage

Store upright in a cool, dry place.

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kids Tranquil Child Alcohol-Free Extract by Oregon's Wild Harvest label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kids Tranquil Child Alcohol-Free Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kids Tranquil Child Alcohol-Free Extract by Oregon's Wild Harvest

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dry Organic Proprietary Blend

250 mg per serving

Other (inactive) ingredients: Glycerin, Citrus Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kids Tranquil Child Alcohol-Free Extract by Oregon's Wild Harvest Drug Interactions

Want to check YOUR meds against Kids Tranquil Child Alcohol-Free Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
994Drugs
935 Moderate 59 Minor

Ingredients driving the most interactions

Chamomile, Dry 960
Passionflower, Dry 836
Peppermint, Dry 796
Catnip, Dry 248

Individual Drug Interactions

The ingredients in Kids Tranquil Child Alcohol-Free Extract interact with 994 drugs. Click any drug to see the details.

4 of the 4 ingredients in Kids Tranquil Child Alcohol-Free Extract interact with drugs. Each result below shows which ingredient is responsible. Chamomile, Dry Passionflower, Dry Peppermint, Dry Catnip, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Kids Tranquil Child Alcohol-Free Extract with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Chamomile, Dry9 drug types · 960 drugs

Cns Depressants

Theoretically, German chamomile might have additive effects when used with CNS depressants.
German chamomile has mild sedative effects. Theoretically, concomitant use with drugs with sedative properties can cause additive effects and side effects.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, large amounts of German chamomile might reduce the effectiveness of oral contraceptives.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, concomitant use of large amounts of German chamomile might interfere with contraceptive drugs through competition for estrogen receptors.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2C9. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2C9 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2D6. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2D6 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP3A4. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP3A4 in patients taking German chamomile.

Likelihood Possible Evidence D
Estrogens

Theoretically, large amounts of German chamomile might reduce the effectiveness of estrogens.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, large amounts of German chamomile might interfere with hormone replacement therapy through competition for estrogen receptors.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, large amounts of German chamomile might interfere with the activity of tamoxifen.
In vitro, German chamomile has demonstrated antiestrogenic activity.

Likelihood Possible Evidence D
Warfarin (Coumadin)

German chamomile might increase the effects of warfarin and increase the risk of bleeding.
In one case, a 70-year-old female taking warfarin developed retroperitoneal hematoma and bilateral recti muscle bleeding along with an INR of 7.9 following ingestion of German chamomile tea 4-5 cups daily and use of a topical chamomile-based lotion applied 4-5 times daily.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
In vitro and animal research shows that German chamomile might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP1A2 in patients taking German chamomile.

Likelihood Possible Evidence D
Chamomile, Dry full monograph & interactions

Passionflower, Dry3 drug types · 836 drugs

Cns Depressants

Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Research in animals and humans shows that passion flower has sedative effects which can be additive when used with sedative medications like lorazepam.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
In vitro research suggests that passion flower can induce CYP3A4 enzymes, albeit to a much lower degree than rifampin, a known CYP3A4 inducer.

Likelihood Possible Evidence D
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Theoretically, passion flower might reduce the bioavailability of OATP2B1 and OATP1A2 substrates.
In vitro research shows that the passion flower constituents apigenin and vitexin inhibit OATP2B1 and OATP1A2. This inhibition may be dose-dependent. One specific high-flavonoid passion flower extract (Valverde) seems to inhibit OATP2B1 and OATP1A2, while another extract with a lower flavonoid concentration (Arkocaps) shows less potent inhibition. OATPs are responsible for the uptake of drugs and other compounds into the body; however, the specific activities of OATP2B1 and OATP1A2 are not well characterized.

Likelihood Possible Evidence D
Passionflower, Dry full monograph & interactions

Peppermint, Dry5 drug types · 796 drugs

Cyclosporine (Neoral, Sandimmune)

Theoretically, peppermint oil might increase the levels and adverse effects of cyclosporine.
In animal research, peppermint oil inhibits cyclosporine metabolism and increases cyclosporine levels. Inhibition of cytochrome P450 3A4 (CYP3A4) may be partially responsible for this interaction. An interaction between peppermint oil and cyclosporine has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, peppermint might increase the levels of CYP2C19 substrates.
In vitro research shows that peppermint oil inhibits CYP2C19. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, peppermint might increase the levels of CYP2C9 substrates.
In vitro research shows that peppermint oil inhibits CYP2C9. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Clinical research in healthy volunteers shows that a single dose of peppermint oil 600 mg inhibits CYP3A4 enzymes and increases the AUC of felodipine, a CYP3A4 substrate. However, in vitro research suggests that peppermint oil only inhibits CYP3A4 at very high concentrations.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, peppermint might increase the levels of CYP1A2 substrates.
In vitro and animal research shows that peppermint oil and peppermint leaf inhibit CYP1A2. However, in clinical research, peppermint tea did not significantly affect the metabolism of caffeine, a CYP1A2 substrate. It is possible that the 6-day duration of treatment may have been too short to identify a difference.

Likelihood Possible Evidence B
Peppermint, Dry full monograph & interactions

Catnip, Dry2 drug types · 248 drugs

Cns Depressants

Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Clinical and animal research shows that catnip has sedative properties.

Likelihood Possible Evidence D
Lithium

Theoretically, catnip might reduce excretion and increase levels of lithium.
Catnip is thought to have diuretic properties which might reduce lithium excretion. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Catnip, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kids Tranquil Child Alcohol-Free Extract, from the product label.

Oregon's Wild Harvest

See all Oregon's Wild Harvest products
Name
Oregon's Wild Harvest
City
Redmond
State
OR
ZipCode
97756
Phone Number
800-316-6869
Web Address
oregonswildharvest.com
Pharmacist Counseling Corner

Kids Tranquil Child Alcohol-Free Extract by Oregon's Wild Harvest: Common Questions

Does Kids Tranquil Child Alcohol-Free Extract by Oregon's Wild Harvest interact with any medications?
Yes. Based on its ingredients, Kids Tranquil Child Alcohol-Free Extract has a known interaction with 994 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kids Tranquil Child Alcohol-Free Extract contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe for kids with ragweed allergies?
No. Chamomile, one of the main ingredients, can trigger allergic reactions in children sensitive to ragweed and related plants—sometimes severe ones. If your child has a ragweed allergy, avoid this product and talk to your pediatrician about alternatives.
Will it really help my child calm down?
The research data we hold doesn't establish that chamomile, passionflower, or catnip actually work for anxiety or ADHD in children. Passionflower is possibly effective for anxiety before medical procedures, and passionflower plus chamomile may help with insomnia, but evidence for everyday use is insufficient. Talk to your child's doctor about what's proven to work.
What are the side effects?
The most common ones are drowsiness, dizziness, headache, stomach upset, and vomiting. A small number of people have had allergic reactions ranging from mild itching to severe anaphylaxis. If your child develops a rash, swelling, trouble breathing, or severe nausea after starting this, stop and seek help right away.
Can I give this along with my child's prescriptions?
That depends on which medications your child takes. Three of the four ingredients interact with a large number of drugs—including sedatives, blood thinners, and many others. Don't start this without checking with your child's pharmacist or doctor first.
What's in the 'Dry Organic Proprietary Blend'?
It contains the four herbs listed separately: chamomile, passionflower, catnip, and peppermint. The blend is listed as proprietary because the exact amounts of each aren't disclosed on the label.
Why is there peppermint in a calming product for kids?
Peppermint is included for its digestive benefits—it's possibly effective for indigestion and likely effective for irritable bowel syndrome. It may help soothe stomach upset sometimes seen alongside anxiety or tension.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kids Tranquil Child Alcohol-Free Extract label
Go deeper

The Full Monographs Behind Kids Tranquil Child Alcohol-Free Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

German Chamomile

Interacts with 960 drugs

German chamomile is a widely used herbal remedy taken mainly as a tea for calming, sleep, and digestive complaints. Early research suggests possible benefits for mild anxiety and some skin o...

Read the full German Chamomile monograph → Herb & supplement monograph

Passion Flower

Interacts with 836 drugs

Passion flower is a traditional calming herb that many people use for anxiety and sleep. Early studies hint it may help with mild anxiety and restlessness, but the evidence is limited and mo...

Read the full Passion Flower monograph → Herb & supplement monograph

Catnip

Interacts with 248 drugs

Catnip is a mint-family herb most often used as a calming tea for sleep, anxiety, and minor digestive upset, but solid human research supporting these uses is lacking. It is generally consid...

Read the full Catnip monograph → Herb & supplement monograph

Peppermint

Interacts with 796 drugs

Peppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms. It is generally well tolerated for most adults, but it can cause heartbu...

Read the full Peppermint monograph →
Sources

Sources & How We Checked

Kids Tranquil Child Alcohol-Free Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 82 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

German Chamomile 15 references
  1. Subiza J, Subiza JL, Hinojosa M, et al. Anaphylactic reaction after the ingestion of chamomile tea; a study of cross-reactivity with other composite pollens. J Allergy Clin Immunol 1989;84:353-8. PubMed
  2. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  3. Viola H, Wasowski C, Levi de Stein M, et al. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med 1995;61:213-6.
  4. van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1982;8:143. PubMed
  5. van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1987;16:50-1. PubMed
  6. Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
  7. Avallone R, Zanoli P, Puia G, et al. Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla. Biochem Pharmacol 2000;59:1387-94. PubMed
  8. Kassi E, Papoutsi Z, Fokialakis N, et al. Greek plant extracts exhibit selective estrogen receptor modulator (SERM)-like properties. J Agric Food Chem 2004;52:6956-61. PubMed
  9. Maliakal PP, Wanwimolruk S. Effect of herbal teas on hepatic drug metabolizing enzymes in rats. J Pharm Pharmacol 2001;53:1323-9. PubMed
  10. Segal R, Pilote L. Warfarin interaction with Matricaria chamomilla. CMAJ 2006;174:1281-2. PubMed
  11. Loggia RD, Traversa U, Scarcia V, et al. Depressive effects of Chamomilla recutita (L.) Rausch, tubular flowers, on central nervous system in mice. Pharmacol Res Commun 1982;14(2):153-162. PubMed
  12. Ganzera M, Schneider P, Stuppner H. Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes. Life Sci 2006;78(8):856-861. PubMed
  13. Benito P, Rodríguez-Perez R, García F, Juste S, Moneo I, Caballero ML. Occupational allergic rhinoconjunctivitis induced by Matricaria chamomilla with tolerance of chamomile tea. J Investig Allergol Clin Immunol. 2014;24(5):369-70. No abstract available.
  14. Braga FT, Santos AC, Bueno PC, et al. Use of Chamomilla recutita in the prevention and treatment of oral mucositis in patients undergoing hematopoietic stem cell transplantation: a randomized, controlled, phase II clinical trial. Cancer Nurs 2015;38(4):32 PubMed
  15. Sarris J, Ravindran A, Yatham LN, et al. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety T

See these in context on the German Chamomile monograph →

Passion Flower 19 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Fisher AA, Purcell P, Le Couteur DG. Toxicity of Passiflora incarnata L. J Toxicol Clin Toxicol 2000;38:63-6.
  4. Akhondzadeh S, Naghavi HR, Shayeganpour A, et al. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam. J Clin Pharm Ther 2001;26:363-7. PubMed
  5. Farnsworth N, Bingel A, Cordell G, et al. Potential value of plants as sources of new antifertility agents I. J Pharm Sci 1975;64:535-98. DOI
  6. Mori A, Hasegawa K, Murasaki M, et al. Clinical evaluation of Passiflamin (passiflora extract) on neurosis - multicenter double blind study in comparison with mexazolam. Rinsho Hyoka (Clinical Evaluation) 1993;21:383-440.
  7. Miyasaka LS, Atallah AN, Soares BG. Passiflora for anxiety disorder. Cochrane Database Syst Rev 2007;(1):CD004518. DOI
  8. Speroni E., Minghetti A. Neuropharmacological activity of extracts from Passiflora incarnata. Planta Med. 1988;54:488-91.
  9. Capasso A., Sorrentino L. Pharmacological studies on the sedative and hypnotic effect of Kava kava and Passiflora extracts combination. Phytomedicine. 2005;12:39-45. PubMed
  10. Carrasco MC, Vallejo JR, Pardo-de-Santayana M, et al. Interactions of Valeriana officinalis L. and Passiflora incarnata L. in a patient treated with lorazepam. Phytother Res. 2009 Dec;23:1795-6.
  11. Smith, G. W., Chalmers, T. M., and Nuki, G. Vasculitis associated with herbal preparation containing Passiflora extract. Br J Rheumatol. 1993;32(1):87-88.
  12. Soulimani, R., Younos, C., Jarmouni, S., Bousta, D., Misslin, R., and Mortier, F. Behavioural effects of Passiflora incarnata L. and its indole alkaloid and flavonoid derivatives and maltol in the mouse. J Ethnopharmacol. 1997;57(1):11-20. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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