Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Chologuardhills Ingredients & Drug Interactions

by Herbal Hills

Chologuardhills label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chologuardhills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chologuardhills is a dietary supplement by Herbal Hills with 5 active ingredients. Its ingredients are commonly taken for heart health and circulation, digestive problems (constipation, diarrhea), cholesterol support.Based on those ingredients, 1,064 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Shunthi Churna, Arjuna Ghana, Shuddha Guggulu. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Chologuardhills by Herbal Hills

Ask about any prescription or over-the-counter medication and we check it for interactions with Chologuardhills by Herbal Hills — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Chologuardhills by Herbal Hills

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Herbal Blend” is a proprietary blend — the label gives one combined amount (550 mg) without saying how much of each component you get.

Chologuardhills contains 5 ingredients, three of which we can identify: Arjuna Ghana (from the arjuna tree), Shunthi Churna (ginger powder), and Shuddha Guggulu (myrrh resin). The product also lists a Proprietary Herbal Blend whose exact breakdown isn't disclosed on the label.

Two other ingredients—Triphala Ghana and Bhavana Dravya (bhringraj)—are included but we have no interaction data for them. The tablet also contains inactive ingredients: xanthan gum, maize starch, silicon dioxide, and magnesium stearate, which are fillers and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: helps maintain healthy cholesterol and cardiovascular function.
  • We looked for evidence on: Coronary heart disease (CHD), Heart failure, Hyperlipidemia, Hypertension, Angina, Atherosclerosis — and 2 related terms.
  • The closest evidence on file: Terminalia is rated "Insufficient Reliable Evidence To Rate" for Angina (Natural Medicines).
  • Also on file: Terminalia is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD), Heart failure, Hyperlipidemia, Hypertension.
  • Also on file: Ginger is rated "Insufficient Reliable Evidence To Rate" for Hyperlipidemia, Hypertension.

The evidence for Chologuardhills' ingredients is limited. For Arjuna Ghana, the data we hold shows insufficient reliable evidence for the conditions listed on the product (obesity, high cholesterol, high blood pressure, and angina).

Shunthi Churna (ginger) has more established uses: it's possibly effective for pregnancy-related nausea and vomiting and menstrual cramps, but possibly ineffective for exercise-related muscle soreness and chemotherapy nausea. For Shuddha Guggulu (myrrh), the evidence we hold is similarly weak—insufficient data for most conditions, and likely ineffective for schistosomiasis.

We have no effectiveness data for Triphala Ghana or Bhavana Dravya.

The evidence, ingredient by ingredient Terminalia Ginger Myrrh

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ginger (Shunthi Churna) is generally well tolerated in typical supplement doses, though higher doses above 5 grams per day increase the risk of side effects. Common mild effects include stomach discomfort, heartburn, diarrhea, and a peppery sensation in the mouth and throat.

Arjuna Ghana is generally well tolerated short-term, but long-term safety isn't well established and varies by product quality. Myrrh (Shuddha Guggulu) may cause diarrhea at higher doses and dermatitis if applied to skin; its long-term oral safety is not well studied.

Regarding pregnancy: ginger is likely safe or possibly safe for morning sickness (with your doctor's approval and modest amounts), but myrrh is likely unsafe and should be avoided in pregnancy. For breastfeeding, ginger is likely safe, but we don't have enough information on myrrh.

Data on Triphala and Bhavana Dravya during pregnancy and nursing isn't on file.

Side effects, ingredient by ingredient Terminalia Ginger Myrrh

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Myrrh, Terminalia, Ginger.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,065 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Chologuardhills, double-check if you're on any of these: blood thinners like warfarin or aspirin (Moderate risk of bleeding), diabetes medications (Moderate risk of low blood sugar), heart drugs including nifedipine or losartan (Moderate risk of increased effects), medications broken down by CYP2D6, CYP2C9, or CYP3A4 enzymes (Moderate risk of increased drug levels), cancer medications, or any stomach acid reducer like omeprazole or muscle relaxer like chlorzoxazone. If you take multiple prescription drugs, the enzyme interactions are a particular concern.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're taking blood thinners, diabetes drugs, heart medications, or multiple prescription drugs, check with your pharmacist before starting this product—the interaction potential is significant. Ginger in this blend may help with nausea or menstrual cramps, but overall evidence for the product's stated uses is weak.

Avoid this product if you're pregnant or breastfeeding, especially the myrrh component. Talk to your pharmacist about whether this is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chologuardhills, straight from the product label.

Brand Herbal Hills
Barcode (UPC) 8906068411135
Net contents 900 Tablet(s)
Market status On market
Date entered into DSLD Jun 23, 2017
DSLD ID 74998
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chologuardhills by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
8906068411135
IngredientAmount% DV
Proprietary Herbal Blend550 mg--
Arjuna Ghana0 NP--
Shunthi Churna0 NP--
Shuddha Guggulu0 NP--
Triphala Ghana0 NP--
Bhavana Dravya: Bhrungraj0 NP--

Other ingredients: Xanthan Gum, Maize Starch, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

General Statements

Suggested Use: ~ Helps maintain healthy cholesterol levels ~ Helps maintain cardio vascular function & healthy circulatory system

Mfg. Lic. No.: PD/AYU/002/10

(An ISO 22000:2005 Certified Company)

Back to nature

Cholesterol support

Formulation with universal secretes of natural bioenhancer

~ Pure ~ Natural ~ Effective

Colour Name: Aluminium Lake of Carmoisine.

Seals/Symbols

JAS-ANZ ICS ISO 22000:2005 Reg. No.: RH91/7301

GMP Good Manufacturing Practice

Halal India www.halalindia.com

Storage

Store in a cool dry place away from direct sunlight.

Precautions

Keep out of reach of children.

Do not use if inner seal is broken or missing.

Caution: Pregnant or lactating women are advised to consume herbal products under the advice of the healthcare practitioner.

Suggested/Recommended/Usage/Directions

Direction For Use: As a dietary supplement take one tablet twice daily preferably after meals. For better results it should be taken with warm water.

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chologuardhills by Herbal Hills label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chologuardhills label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chologuardhills by Herbal Hills

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Herbal Blend

550 mg per serving

Other (inactive) ingredients: Xanthan Gum, Maize Starch, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chologuardhills by Herbal Hills Drug Interactions

Want to check YOUR meds against Chologuardhills?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,064Drugs
993 Moderate 71 Minor

Ingredients driving the most interactions

Shunthi Churna 1,007
Arjuna Ghana 933
Shuddha Guggulu 88

Individual Drug Interactions

The ingredients in Chologuardhills interact with 1,064 drugs. Click any drug to see the details.

3 of the 5 ingredients in Chologuardhills interact with drugs. Each result below shows which ingredient is responsible. Shunthi Churna Arjuna Ghana Shuddha Guggulu

Each ingredient & the kinds of drugs it affects

For each ingredient in Chologuardhills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Shunthi Churna14 drug types · 1,007 drugs

Anticoagulant/Antiplatelet Drugs

Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, research is conflicting.
Laboratory research suggests that ginger inhibits thromboxane synthetase and decreases platelet aggregation. However, this has not been demonstrated unequivocally in humans, with mixed results from clinical trials. Theoretically, excessive amounts of ginger might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Animal and human research suggests that ginger might increase insulin levels and/or decrease blood glucose levels.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Ginger might increase or decrease the levels of CYP3A4 substrates.
In vitro research and some case reports suggest that ginger inhibits CYP3A4 activity. Three case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are CYP3A4 substrates (imatinib, dabrafenib, and crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Conversely, other in vitro research suggests that ginger induces CYP3A4 activity, leading to reduced levels of CYP3A4 substrates. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Losartan (Cozaar)

Theoretically, ginger might increase levels of losartan and the risk of hypotension.
In animal research, ginger increased the levels and hypotensive effects of a single dose of losartan. It is not clear if ginger alters the concentration or effects of losartan when taken continuously. Additionally, this interaction has not been shown in humans.

Likelihood Possible Evidence D
Nifedipine (Procardia)

Ginger may have antiplatelet effects and increase the risk of bleeding if used with nifedipine.
Clinical research shows that combined treatment with ginger 1 gram plus nifedipine 10 mg significantly inhibits platelet aggregation when compared to nifedipine or ginger alone.

Likelihood Possible Evidence B
P-Glycoprotein Substrates

Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
In vitro research and case reports suggest that ginger inhibits drug efflux by P-gp, potentially increasing absorption and serum levels of P-gp substrates. Two case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are P-gp substrates (trametinib, crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.

Likelihood Possible Evidence D
Phenprocoumon (Marcoumar, Others)

Ginger might increase the risk of bleeding with phenprocoumon.
Phenprocoumon, a warfarin-related anticoagulant, might increase the international normalized ratio (INR) when taken with ginger. There is one case report of a 76-year-old woman with a stable INR on phenprocoumon that increased to greater than 10 when she began consuming dried ginger and ginger tea.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Ginger might increase the risk of bleeding with warfarin.
Laboratory research suggests that ginger might inhibit thromboxane synthetase and decrease platelet aggregation. In one case report, ginger increased the INR when taken with phenprocoumon, which has similar pharmacological effects as warfarin. In another case report, ginger increased the INR when taken with a combination of warfarin, hydrochlorothiazide, and acetaminophen. A longitudinal analysis suggests that taking ginger increases the risk of bleeding in patients taking warfarin for at least 4 months. However, research in healthy people suggests that ginger has no effect on INR, or the pharmacokinetics or pharmacodynamics of warfarin. Until more is known, monitor INRs closely in patients taking large amounts of ginger.

Likelihood Possible Evidence B
Calcium Channel Blockers

Theoretically, taking ginger with calcium channel blockers might increase the risk of hypotension.
Some animal and in vitro research suggests that ginger has hypotensive and calcium channel-blocking effects. Another animal study shows that concomitant administration of ginger and the calcium channel blocker amlodipine leads to greater reductions in blood pressure when compared with amlodipine alone.

Likelihood Unlikely Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, when taken prior to cyclosporine, ginger might decrease cyclosporine levels.
In an animal model, ginger juice taken 2 hours prior to cyclosporine administration reduced the maximum concentration and area under the curve of cyclosporine by 51% and 40%, respectively. This effect was not observed when ginger juice and cyclosporine were administered at the same time.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ginger might increase the levels of CYP1A2 substrates.
In vitro research shows that ginger inhibits CYP1A2 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, ginger might increase the levels of CYP2B6 substrates.
In vitro research shows that ginger inhibits CYP2B6 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, ginger might increase the levels of CYP2C9 substrates.
In vitro research shows that ginger inhibits CYP2C9 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Metronidazole (Flagyl)

Theoretically, ginger might increase levels of metronidazole.
In an animal model, ginger increased the absorption and plasma half-life of metronidazole. In addition, the elimination rate and clearance of metronidazole was significantly reduced.

Likelihood Possible Evidence D
Shunthi Churna full monograph & interactions

Arjuna Ghana7 drug types · 933 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.

Likelihood Possible Evidence D
Chlorzoxazone (Parafon Forte, Paraflex)

Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.

Likelihood Possible Evidence D
Omeprazole (Prilosec)

Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.

Likelihood Possible Evidence D
Arjuna Ghana full monograph & interactions

Shuddha Guggulu2 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, myrrh might increase the risk of hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research suggests that myrrh has hypoglycemic effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, myrrh might decrease the effectiveness of warfarin.
In one case, a patient who was previously stable on warfarin had a significant decline in international normalized ratio (INR) following consumption of an aqueous extract of myrrh.

Likelihood Possible Evidence D
Shuddha Guggulu full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chologuardhills, from the product label.

Herbal Hills

See all Herbal Hills products
Name
Isha Agro Developers Pvt. Ltd.
Street Address
55-A/B, Lonavala Co-op. Indl. Est. Ltd.
City
Nangargaon, Lonavala, Taluka-Maval, Dist. Pune,
State
Maharashtra
ZipCode
410401
Web Address
0091 22 2868 6868
Pharmacist Counseling Corner

Chologuardhills by Herbal Hills: Common Questions

Does Chologuardhills by Herbal Hills interact with any medications?
Yes. Based on its ingredients, Chologuardhills has a known interaction with 1,064 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chologuardhills contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will ginger in this product help my nausea?
Ginger (Shunthi Churna) is possibly effective for pregnancy-related nausea and vomiting, so it may help—but check with your doctor first if you're pregnant. For other types of nausea, the evidence we hold is weaker. Keep doses moderate (don't exceed 5 grams per day) to minimize stomach upset.
What side effects might I get from taking this?
The most likely are mild: stomach discomfort, heartburn, diarrhea, or a peppery sensation in your mouth and throat from the ginger. At higher doses, these become more common. Myrrh may also cause diarrhea. If you have a sensitive stomach, ginger in capsule form rather than powder may be gentler.
Is this safe to take while pregnant or nursing?
Ginger in this product is likely or possibly safe for morning sickness during pregnancy, but only in typical food amounts and with your doctor's approval. Myrrh, however, is likely unsafe in pregnancy and should be avoided. For breastfeeding, ginger is likely safe, but we don't have enough data on myrrh. Talk to your doctor or pharmacist before taking this.
Does this product actually work for high cholesterol and high blood pressure?
The evidence we hold shows insufficient reliable data for Arjuna Ghana (the main ingredient targeting these) for high cholesterol or high blood pressure. The other ingredients don't have strong evidence either. Don't rely on this alone if you have these conditions.
What does each ingredient in this do?
Arjuna Ghana comes from the arjuna tree and is traditionally used for heart health; ginger (Shunthi Churna) is well known for nausea and inflammation; myrrh (Shuddha Guggulu) has a long history in traditional medicine for digestion and inflammation. Triphala and bhringraj are traditional Ayurvedic ingredients, but we have no specific interaction or effectiveness data for them.
Are there any fillers or just the active herbs?
The product contains inactive ingredients—xanthan gum, maize starch, silicon dioxide, and magnesium stearate—which are binders and anti-caking agents common in tablets. So it's not just herbs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chologuardhills label
Go deeper

The Full Monographs Behind Chologuardhills’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Terminalia

Interacts with 933 drugs

Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes. Some small studies suggest possible ben...

Read the full Terminalia monograph → Herb & supplement monograph

Ginger

Interacts with 1,007 drugs

Ginger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nausea and vomiting, including from motion sickness, pr...

Read the full Ginger monograph → Herb & supplement monograph

Myrrh

Interacts with 88 drugs

Myrrh is a fragrant gum resin from Commiphora trees that has long been used in mouthwashes, throat remedies, and skin care. Modern evidence for most of its uses is limited and comes mostly f...

Read the full Myrrh monograph →
Sources

Sources & How We Checked

Chologuardhills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 81 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Terminalia 9 references
  1. Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
  2. Rao, N. K. and Nammi, S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC.Complement Altern.Med 2006;6:17. PubMed
  3. Murali, Y. K., Anand, P., Tandon, V., Singh, R., Chandra, R., and Murthy, P. S. Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced
  4. Senthilkumar, G. P. and Subramanian, S. Evaluation of antioxidant potential of Terminalia chebula fruits studies in streptozotocin-induced diabetic rats. Pharmaceutical Biology (Netherlands) 2007;45:511-518.
  5. Malik N, Dhawan V, Bahl A, Kaul D. Inihbitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease. Platelets. 2009;20(3):183-1190.
  6. Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
  7. Wu G, Dong Z, Dong J, et al. Effects of mongolian medicine Terminalia chebula Retz. on 6 CYP450 enzymes in rats. Int J Clin Exp Pathol 2020;13(12):3128-3138.
  8. Das A, Naveen J, Sreerama YN, Gnanesh Kumar BS, Baskaran V. Low-glycemic foods with wheat, barley and herbs (Terminalia chebula, Terminalia bellerica and Emblica officinalis) inhibit a-amylase, a-glucosidase and DPP-IV activity in high fat and low dose st
  9. Eltimamy M, Elshamarka M, Aboelsaad M, Sayed M, Moawad H. Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats. J Diabetes Metab Disord 2022;21(1):159-170. PubMed

See these in context on the Terminalia monograph →

Ginger 64 references
  1. Fischer-Rasmussen W, Kjaer SK, Dahl C, Asping U. Ginger treatment of hyperemesis gravidarum. Eur J Obstet Gynecol Reprod Biol 1991;38:19-24. PubMed
  2. Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev 2000;(2):CD000145. PubMed
  3. Vutyavanich T, Kraisarin T, Ruangsri R. Ginger for nausea and vomiting in pregnancy: randomized, double-masked, placebo-controlled trial. Obstet Gynecol 2001;97:577-82. DOI
  4. Backon J. Ginger in preventing nausea and vomiting of pregnancy; a caveat due to its thromboxane synthetase activity and effect on testosterone binding. Eur J Obstet Gynecol Reprod Biol 1991;42:163-4. PubMed
  5. Srivastava KC. Effect of onion and ginger consumption on platelet thromboxane production in humans. Prostaglandins Leukot Essent Fatty Acids 1989;35:183-5. PubMed
  6. Stewart JJ, Wood MJ, Wood CD, Mims ME. Effects of ginger on motion sickness susceptibility and gastric function. Pharmacology 1991;42:111-20. PubMed
  7. Smith C, Crowther C, Willson K, et al. A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstet Gynecol 2004;103:639-45. PubMed
  8. Portnoi G, Chng LA, Karimi-Tabesh L, et al. Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancy. Am J Obstet Gynecol 2003;189:1374-7.. PubMed
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See these in context on the Ginger monograph →

Myrrh 8 references
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  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
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See these in context on the Myrrh monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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