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Dietary supplement

Citrus Bergamot 500 mg Ingredients & Drug Interactions

by Sunergetic

Citrus Bergamot 500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Citrus Bergamot 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Citrus Bergamot 500 mg is a dietary supplement by Sunergetic with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart and metabolic health, anxiety and stress (aromatherapy).Based on those ingredients, 410 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bergamonte. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Citrus Bergamot 500 mg by Sunergetic

Ask about any prescription or over-the-counter medication and we check it for interactions with Citrus Bergamot 500 mg by Sunergetic — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Citrus Bergamot 500 mg by Sunergetic

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bergamot extract (Bergamonte), 500 mg per capsule. Bergamot is a citrus fruit whose juice and peel have been studied for effects on cholesterol and liver health.

The capsule itself is made from hypromellose, with magnesium stearate and silicon dioxide as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Bergamot's overall clinical evidence instead.

Moderate

Some clinical evidence supports Bergamot for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Hyperlipidemia — rated "Possibly Effective" (Natural Medicines).

Bergamot extract is possibly effective for high cholesterol (hyperlipidemia). For mental alertness, the evidence suggests it's possibly ineffective.

For nonalcoholic fatty liver disease and autism spectrum disorder, we don't have enough reliable evidence to rate how well it works — more research is needed.

The evidence, ingredient by ingredient Bergamot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The oral extract appears generally well tolerated when used short-term; one trial participant reported heartburn. The essential oil, by contrast, can be toxic if swallowed and may cause sun-related skin reactions, so this product is for oral extract, not oil.

During pregnancy, there isn't enough safety information, so the data advises against it. Breastfeeding safety is unknown, so avoiding it is the safer choice.

If you're pregnant or breastfeeding, talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Bergamot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bergamot.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 410 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check your medications with your doctor or pharmacist if you take photosensitizing drugs (medications that make your skin more sun-sensitive) or antidiabetes drugs — both carry Moderate interaction risk with bergamot. These two categories account for some of the 410 individual medications that may interact; use the search tool here to confirm your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Citrus Bergamot might help if you're looking to support cholesterol levels, though the evidence is modest. You'll want to be cautious if you take diabetes medications or drugs that increase sun sensitivity — check those combinations first with your doctor or pharmacist.

It's not recommended during pregnancy or breastfeeding. Before you start, run through your medication list on this page to make sure there are no interactions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Citrus Bergamot 500 mg, straight from the product label.

Brand Sunergetic
Barcode (UPC) X002C8MSTP
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2022
DSLD ID 276817
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Citrus Bergamot 500 mg by Sunergetic, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
X002C8MSTP
IngredientAmount% DV
Bergamonte500 mg--

Other ingredients: Hypromellose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule 1 to 2 times daily preferably with meals or as directed by a healthcare professional.

Precautions

Caution: Do not exceed recommended dose.

This product is not intended for pregnant or nursing mothers or children under 18.

This product is not intended for pregnant or nursing mothers or children under 18.

If you have a known medical condition, including diabetes, or have questions about the advisability of taking this product, consult your physician before use.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Helps maintain cholesterol levels already within the normal range Helps maintain blood sugar levels already within the normal range Helps support cardiovascular health

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Bergamonte is a registered trademark of HP Ingredients Corporation.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Citrus Bergamot 500 mg by Sunergetic label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Citrus Bergamot 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Citrus Bergamot 500 mg by Sunergetic

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Bergamonte

Interacts with
410 drugs
500 mg per serving Form: Bergamot Orange Fruit Extract

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but...

Bergamonte monograph & interactions

Other (inactive) ingredients: Hypromellose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Citrus Bergamot 500 mg by Sunergetic Drug Interactions

Want to check YOUR meds against Citrus Bergamot 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
410Drugs
410 Moderate

Ingredients driving the most interactions

Bergamonte 410

Individual Drug Interactions

The ingredients in Citrus Bergamot 500 mg interact with 410 drugs. Click any drug to see the details.

1 of the 1 ingredient in Citrus Bergamot 500 mg interact with drugs. Each result below shows which ingredient is responsible. Bergamonte

Each ingredient & the kinds of drugs it affects

For each ingredient in Citrus Bergamot 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bergamonte2 drug types · 410 drugs

Antidiabetes Drugs

Theoretically, taking bergamot with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that bergamot juice has hypoglycemic effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.
Bergamot contains bergapten, which has photosensitizing effects.

Likelihood Probable Evidence D
Bergamonte full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Citrus Bergamot 500 mg, from the product label.

Sunergetic

See all Sunergetic products
Name
Sunergized LLC
City
Woodbury
State
NY
ZipCode
11797
Phone Number
(866) 839-5329
Web Address
www.sunergeticproducts.com
Pharmacist Counseling Corner

Citrus Bergamot 500 mg by Sunergetic: Common Questions

Does Citrus Bergamot 500 mg by Sunergetic interact with any medications?
Yes. Based on its ingredients, Citrus Bergamot 500 mg has a known interaction with 410 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Citrus Bergamot 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my cholesterol?
Bergamot extract is possibly effective for high cholesterol, so it may help — but the evidence is not ironclad. Talk with your doctor about whether it fits into your overall cholesterol management plan.
Can I take this if I'm on diabetes medication?
Not without checking first. Bergamot may lower blood sugar, so combining it with diabetes drugs could raise the risk of low blood sugar. Confirm with your doctor or pharmacist before starting.
Is the essential oil the same as what's in this capsule?
No. This product is an oral extract. The essential oil can be toxic if swallowed and causes sun-related skin reactions, so do not ingest the oil form.
What are the side effects?
When taken by mouth short-term, the extract is generally well tolerated. One person in a trial reported heartburn. If you apply bergamot topically or use the essential oil, you risk blisters, redness, and photosensitivity, especially if you have fair skin.
Is it safe during pregnancy?
No. There isn't enough safety information, so the data advises against bergamot supplements during pregnancy. If you're pregnant, talk with your doctor before taking this.
What if I'm in the sun a lot?
Be cautious. Bergamot contains a compound that can increase sun sensitivity, especially if you're taking any medication that makes your skin more sun-sensitive. Discuss sun exposure and this product with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Citrus Bergamot 500 mg label
Go deeper

The Full Monographs Behind Citrus Bergamot 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bergamot

Interacts with 410 drugs

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but promising research. The essential oil i...

Read the full Bergamot monograph →
Sources

Sources & How We Checked

Citrus Bergamot 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bergamot 17 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . PubMed
  4. Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J.Am.Acad.Dermatol. 2001;45(3):458-461. PubMed
  5. Finsterer, J. Earl Grey tea intoxication. Lancet 4-27-2002;359(9316):1484. PubMed
  6. Gruson, L. M. and Chang, M. W. Berloque dermatitis mimicking child abuse. Arch.Pediatr.Adolesc.Med. 2002;156(11):1091-1093. PubMed
  7. Weisenseel, P. and Woitalla, S. [Toxic mustard plaster dematitis and phototoxic dematitis after application of bergamot oil]. MMW.Fortschr.Med. 12-15-2005;147(51-52):53, 55.
  8. Placzek, M., Fromel, W., Eberlein, B., Gilbertz, K. P., and Przybilla, B. Evaluation of phototoxic properties of fragrances. Acta Derm.Venereol. 2007;87(4):312-316. PubMed
  9. Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. F PubMed
  10. Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil. Effects of a cinnamate sunscreen. J.Photochem.Photobiol.B 1990;7(2-4):199-208. PubMed
  11. Young, A. R., Walker, S. L., Kinley, J. S., Plastow, S. R., Averbeck, D., Morliere, P., and Dubertret, L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model. J.P PubMed
  12. Girard, J., Unkovic, J., Delahayes, J., and Lafille, C. [Phototoxicity of Bergamot oil. Comparison between humans and guinea pigs]. Dermatologica 1979;158(4):229-243.
  13. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives. Contact Dermatitis 1977;3(5):225-23 PubMed
  14. Zacher, K. D. and Ippen, H. [Contact dermatitis caused by bergamot oil]. Derm.Beruf.Umwelt. 1984;32(3):95-97.
  15. Yasui, Y. and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting. J.Dermatol. 1994;21(5):319-322. PubMed
  16. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. I. Characterization and quantification of the photoactive component. Br.J.Dermatol. 1977;96(5):475-482. PubMed
  17. Bruno A, Pandolfo G, Crucitti M, Cedro C, Zoccali RA, Muscatello MRA. Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study. J Clin Psychopharmacol 2017;37(4):468-71. PubMed

See these in context on the Bergamot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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