Interactions on record — worth a quick check against your medications. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

CLA Ingredients & Drug Interactions

by OL Olympian Labs Performance Sports Nutrition

Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

CLA is a dietary supplement by OL Olympian Labs Performance Sports Nutrition with 5 active ingredients. Its ingredients are commonly taken for heart health, healthy cooking fat, skin moisturizing.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oleic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of CLA by OL Olympian Labs Performance Sports Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Safflower/Sunflower Oil concentrate” is listed as a grouped ingredient — the label gives one combined amount (3 Gram(s)) without saying how much of each component you get.

This product contains five active ingredients: Stearic Acid, Conjugated Linoleic Acid, Oleic Acid, Alpha-Linolenic Acid, and Palmitic Acid — a blend of fatty acids. The inactive ingredients are gelatin, glycerin, water, caramel, and carob; they're the capsule and flavoring, not the active part.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Oleic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: reduce body fat and increase lean muscle mass.
  • We looked for evidence on: Obesity, weight management, body composition.
  • The closest evidence on file: Oleic Acid is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

Oleic Acid is rated possibly effective for high cholesterol (hypercholesterolemia) and coronary heart disease based on the data we hold. We don't have effectiveness ratings for the other four active ingredients in this product, so the evidence for their clinical benefit isn't established in our records.

The evidence, ingredient by ingredient Oleic Acid

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oleic Acid is generally recognized as safe in normal food amounts — it's a main component of olive oil. The safety data we hold cautions, though, that concentrated supplement doses haven't been well studied in pregnancy or breastfeeding, so there isn't enough information to know either way.

The ingredient was otherwise well tolerated; no adverse effects are documented in our data.

Side effects, ingredient by ingredient Oleic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oleic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (blood sugar–lowering medications), double-check with your pharmacist before starting this product. The oleic acid in it may increase their effect on blood sugar.

We hold no interaction data for the other four active ingredients, so that's the only interaction we can flag from our records.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

This product may be worth considering if you're interested in a source of fatty acids for cholesterol or heart health, though the evidence is preliminary. If you take antidiabetes medication, talk it over with your doctor or pharmacist first — the oleic acid in this blend might affect how those drugs work.

For pregnancy or breastfeeding, there isn't enough safety data to know if this concentrated form is right for you; check with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CLA, straight from the product label.

Brand OL Olympian Labs Performance Sports Nutrition
Barcode (UPC) 710013001160
Net contents 90 Softgel(s)
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 175807
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CLA by OL Olympian Labs Performance Sports Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Softgel(s)
Maximum serving Sizes:
3 Softgel(s)
Servings per container
30
UPC/BARCODE
710013001160
IngredientAmount% DV
Calories30 Calorie(s)--
Stearic Acid0 NP--
Calories from Fat27 Calorie(s)--
Conjugated Linoleic Acid0 NP--
Oleic Acid0 NP--
Alpha-Linolenic Acid0 NP--
Palmitic Acid0 NP--
Total Fat3 Gram(s)5%
Safflower/Sunflower Oil concentrate3 Gram(s)--

Other ingredients: Gelatin, Glycerin, Water, Caramel, Carob

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

CLA (Conjugated Linoleic Acid) is a targeted, stimulant free solution to help maximize your fitness efforts, reduce body fat and increase lean muscle mass. Studies suggest CLA works by increasing your metabolic rate to help burn calories and pushing glucose (blood sugar) into muscle cells instead of letting it turn into body fat.

Olympian Labs, Inc. products are made with the highest quality ingredients and manufactured according to Good Manufacturing Practices (cGMP).

Helps reduce body fat Helps increase lean muscle mass Helps increase metabolic rate Muscle growth Fat burner

Made in USA

Suggested/Recommended/Usage/Directions

CLA, when used in conjunction with a regimented diet and exercise plan, helps you get the muscle tone you want. CLA can also be stacked with additional weight management products.

Daily Suggested Use: As a dietary supplement, take three (3) softgels daily, or as directed by a healthcare professional.

Precautions

Caution: If you are pregnant or nursing, have a medical condition, or are taking medication, consult your healthcare professional before using this or any other nutritional supplement.

Discontinue use if allergic reaction occurs.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Store in a cool, dry place.

General

REV 02.25.15

Formula

CLA 3000 mg per serving

Formulation

Allergen free

FDA Statement of Identity

Dietary Supplement

See for yourself

CLA by OL Olympian Labs Performance Sports Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in CLA by OL Olympian Labs Performance Sports Nutrition

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Safflower/Sunflower Oil concentrate

3 Gram(s) per serving
  • › Stearic Acid
  • › Conjugated Linoleic Acid
  • Oleic Acid
  • › Alpha-Linolenic Acid
  • › Palmitic Acid

Other (inactive) ingredients: Gelatin, Glycerin, Water, Caramel, Carob. These complete the product’s ingredient list but are not active constituents.

Interaction report

CLA by OL Olympian Labs Performance Sports Nutrition Drug Interactions

Want to check YOUR meds against CLA?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in CLA with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oleic Acid1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, oleic acid might increase the effects of antidiabetes drugs. Preliminary clinical research in patients with type 2 diabetes taking oral hypoglycemic drugs shows that eating a diet rich in oleic acid from olive oil decreases fasting blood glucose levels when compared to eating a diet rich in linoleic acid from sunflower oil. It is unknown if taking oleic acid supplements would have this effect or if this change is clinically significant. Until more is known, use caution. Dose adjustment may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for CLA, from the product label.

OL Olympian Labs Performance Sports Nutrition

See all OL Olympian Labs Performance Sports Nutrition products
Name
Olympian Labs, Inc.
City
Phoenix
State
AZ
ZipCode
85027
Phone Number
1.800.473.5883
Web Address
www.olympianlabs.com
Pharmacist Counseling Corner

CLA by OL Olympian Labs Performance Sports Nutrition: Common Questions

Does CLA by OL Olympian Labs Performance Sports Nutrition interact with any medications?
Yes. Based on its ingredients, CLA has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CLA contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this product lower my blood sugar?
We don't have clinical evidence showing this CLA product lowers blood sugar itself. Oleic Acid may theoretically increase the effects of antidiabetes drugs you're already taking, which could shift your blood sugar — but that's different from the product doing it on its own. Talk with your doctor or pharmacist about what to expect.
Is it safe to take while I'm pregnant or breastfeeding?
The safety data we hold on Oleic Acid doesn't give us a clear answer — food amounts are fine, but concentrated supplement doses haven't been well studied in pregnancy or breastfeeding. There isn't enough information to know either way, so you'll want to ask your doctor or pharmacist for personalized advice.
What's Conjugated Linoleic Acid and why is it in here?
Conjugated Linoleic Acid is a type of fatty acid — it's the 'CLA' in the product name. We don't hold interaction or effectiveness data for it, so I can't tell you what it's meant to do in this blend or how it interacts with medications.
Does this product have any fillers?
Yes — the inactive ingredients are gelatin, glycerin, water, caramel, and carob. Those are the capsule material and flavoring, not the active ingredients.
Are there any side effects I should know about?
No adverse effects are documented in our data for the ingredients we checked. That doesn't guarantee none will happen, but based on what we hold, you shouldn't expect side effects from these particular components.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if CLA is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CLA label
Sources

Sources & How We Checked

CLA's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oleic Acid 19 references
  1. Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed
  2. Gillingham, L. G., Gustafson, J. A., Han, S. Y., Jassal, D. S., and Jones, P. J. High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects. Br J Nutr 2011;105(3):417-427. PubMed
  3. Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiova
  4. Cater, N. B., Heller, H. J., and Denke, M. A. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am.J Clin.Nutr PubMed
  5. Mozaffarian D, Clarke R. Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils. Eur J Clin Nutr. 2009;63(Suppl 2):S22-33. PubMed
  6. Cao Y, Hou L, Wang W. Dietary total fat and fatty acids intake, serum fatty acids and risk of breast cancer: A meta-analysis of prospective cohort studies. Int J Cancer. 2016;138(8):1894-904. doi: 10.1002/ijc.29938. PubMed
  7. FDA completes review of qualified health claim petition for oleic acid and the risk of coronary heart disease. November 2018. Available at: www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm624758.htm. Accessed January 25, 2019.
  8. Liu X, Kris-Etherton PM, West SG, et al. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity. 2016;24(11):2261-2268. PubMed
  9. Bowen KJ, Kris-Etherton PM, West SG, et al. Diets enriched with conventional or high-oleic acid canola oils lower atherogenic lipids and lipoproteins compared to a diet with a western fatty acid profile in adults with central adiposity. J Nutr. 2019;149(3 PubMed
  10. Steffen BT, Duprez D, Szklo M, Guan W, Tsai MY. Circulating oleic acid levels are related to greater risks of cardiovascular events and all-cause mortality: The Multi-Ethnic Study of Atherosclerosis. J Clin Lipidol. 2018;12(6):1404-1412. PubMed
  11. Banim PJ, Luben R, Khaw KT, Hart AR. Dietary oleic acid is inversely associated with pancreatic cancer - Data from food diaries in a cohort study. Pancreatology. 2018;18(6):655-660. PubMed
  12. Morin SJ, Gaziano JM, Djoussé L. Relation between plasma phospholipid oleic acid and risk of heart failure. Eur J Nutr. 2018;57(8):2937-2942. PubMed
  13. Samieri C, Féart C, Proust-Lima C, et al. Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City Study. Neurology. 2011;77(5):418-25. PubMed
  14. Compher CW, Kinosian BP, Rubesin SE, Ratcliffe SJ, Metz DC. Energy absorption is reduced with oleic acid supplements in human short bowel syndrome. JPEN J Parenter Enteral Nutr. 2009;33(1):102-8. PubMed
  15. Ben Fradj MK, Ouanes Y, Hadj-Taieb S, et al. Decreased oleic acid and marine n?-?3 polyunsaturated fatty acids in Tunisian patients with urothelial bladder cancer. Nutr Cancer. 2018;70(7):1043-1050.
  16. de Silva PS, Luben R, Shrestha SS, Khaw KT, Hart AR. Dietary arachidonic and oleic acid intake in ulcerative colitis etiology: a prospective cohort study using 7-day food diaries. Eur J Gastroenterol Hepatol. 2014;26(1):11-8. PubMed
  17. Higashi K, Shige H, Ito T, et al. Effect of a low-fat diet enriched with oleic acid on postprandial lipemia in patients with type 2 diabetes mellitus. Lipids. 2001;36(1):1-6. PubMed
  18. Lin HC, van Citters GW, Heimer F, Bonorris G. Slowing of gastrointestinal transit by oleic acid: a preliminary report of a novel, nutrient-based treatment in humans. Dig Dis Sci. 2001;46(2):223-9. PubMed
  19. Li D, Tong Y, Li Y. Associations between dietary oleic acid and linoleic acid and depressive symptoms in perimenopausal women: The Study of Women's Health Across the Nation. Nutrition. 2020 Mar;71:110602. PubMed

See these in context on the Oleic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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