Coenzymated B-1 Cocarboxylase Ingredients & Drug Interactions
by Source Naturals
What is this page for?
First and foremost: checking Coenzymated B-1 Cocarboxylase against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Coenzymated B-1 Cocarboxylase is a dietary supplement by Source Naturals with 1 active ingredient. Its ingredients are commonly taken for preventing or treating thiamine deficiency, beriberi, wernicke-korsakoff syndrome (alcohol-related).Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Thiamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Coenzymated B-1 Cocarboxylase by Source Naturals
Ask about any prescription or over-the-counter medication and we check it for interactions with Coenzymated B-1 Cocarboxylase by Source Naturals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Coenzymated B-1 Cocarboxylase by Source Naturals
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- “Thiamine” is listed as a grouped ingredient — the label gives one combined amount (16 mg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Coenzymated B-1 Cocarboxylase, straight from the product label.
| Brand | Source Naturals |
|---|---|
| Barcode (UPC) | 021078009320 |
| Net contents | 30 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Jun 22, 2023 |
| DSLD ID | 295649 |
| Product type | Vitamin |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Coenzymated B-1 Cocarboxylase by Source Naturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Thiamine | 16 mg | 1067% |
| Cocarboxylase | 25 mg | -- |
Other ingredients: Sorbitol, Mannitol, Sodium Citrate, natural Peppermint flavor, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Vitamin Supplement
Formula
The benefits of coenzymated sublingual vitamins In order for vitamins to be utilized by the body, they must first be converted into their active coenzyme forms. Sublingual coenzymated B-1 goes directly into your bloodstream in its active form, ready to go to work immediately. This avoids the loss that may occur not only during digestion, but during the liver's conversion process as well. Thiamin diphosphate (TDP), also called thiamin pyrophosphate (TTP) or cocarboxylase, is the active, coenzyme form of vitamin B-1.
Suggested/Recommended/Usage/Directions
Suggested use: 1 tablet daily. Place tablet under the tongue and allow to dissolve slowly, altering the position of the tablet to avoid prolonged contact with the same area.
Precautions
Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.
Do not use if either tamper-evident seal is broken or missing.
Keep out of the reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Copyright Source Naturals, Inc.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Coenzymated B-1 Cocarboxylase by Source Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Coenzymated B-1 Cocarboxylase by Source Naturals
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.
Thiamine
Interacts with3 drugs
Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get eno...
Thiamine monograph & interactions- › Cocarboxylase
Other (inactive) ingredients: Sorbitol, Mannitol, Sodium Citrate, Natural Peppermint flavor, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Coenzymated B-1 Cocarboxylase by Source Naturals Drug Interactions
Coenzymated B-1 Cocarboxylase contains a single active ingredient, and it has known interactions with 3 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Coenzymated B-1 Cocarboxylase?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Coenzymated B-1 Cocarboxylase interact with 3 drugs. Click any drug to see the details.
1 of the 1 ingredient in Coenzymated B-1 Cocarboxylase interact with drugs. Each result below shows which ingredient is responsible. Thiamine
Sulfadiazine, TrimethoprimCoptin
How Sulfadiazine, Trimethoprim interacts with Coenzymated B-1 Cocarboxylase — through 1 ingredient. Tap an ingredient for the detail:
ThiamineTrimethoprim (proloprim) Minor
Interaction Summary
Trimethoprim might increase blood levels of thiamine.
Read the full Thiamine + Sulfadiazine, Trimethoprim interactionSulfamethoxazole, TrimethoprimBactrim, Bactrim DS, Bactrim IV, Cotrim, Cotrim DS, Cotrimix +9 more
How Sulfamethoxazole, Trimethoprim interacts with Coenzymated B-1 Cocarboxylase — through 1 ingredient. Tap an ingredient for the detail:
ThiamineTrimethoprim (proloprim) Minor
Interaction Summary
Trimethoprim might increase blood levels of thiamine.
Read the full Thiamine + Sulfamethoxazole, Trimethoprim interactionTrimethoprimProloprim, Trimpex
How Trimethoprim interacts with Coenzymated B-1 Cocarboxylase — through 1 ingredient. Tap an ingredient for the detail:
ThiamineTrimethoprim (proloprim) Minor
Interaction Summary
Trimethoprim might increase blood levels of thiamine.
Read the full Thiamine + Trimethoprim interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Coenzymated B-1 Cocarboxylase with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Thiamine
Trimethoprim (Proloprim)
Trimethoprim might increase blood levels of thiamine.
In vitro, animal, and clinical research suggest that trimethoprim inhibits intestinal thiamine transporter ThTR-2, hepatic transporter OCT1, and renal transporters OCT2, MATE1, and MATE2, resulting in paradoxically increased thiamine plasma concentrations.
Brand information
Manufacturer and brand details for Coenzymated B-1 Cocarboxylase, from the product label.
Source Naturals
- Name
- Source Naturals, Inc.
- Street Address
- P. O. Box 2118
- City
- Santa Cruz
- State
- CA
- ZipCode
- 95062
- Web Address
- www.sourcenaturals.com
Coenzymated B-1 Cocarboxylase by Source Naturals: Common Questions
Does Coenzymated B-1 Cocarboxylase by Source Naturals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Coenzymated B-1 Cocarboxylase is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Coenzymated B-1 Cocarboxylase’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Coenzymated B-1 Cocarboxylase's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Thiamine 7 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Rogovik, A. L., Vohra, S., and Goldman, R. D. Safety considerations and potential interactions of vitamins: should vitamins be considered drugs? Ann.Pharmacother. 2010;44(2):311-324. PubMed
- Arruti N, Bernedo N, Audicana MT, Villarreal O, Uriel O, Muñoz D. Systemic allergic dermatitis caused by thiamine after iontophoresis. Contact Dermatitis. 2013 Dec;69(6):375-6. PubMed
- Thiamine hydrochloride injection package insert. Lake Zurich, IL: Fresenius Kabi, LLC; September 2019.
- Vora B, Wen A, Yee SW, et al. The Effect of Trimethoprim on Thiamine Absorption: A Transporter-Mediated Drug-Nutrient Interaction. Clin Pharmacol Ther 2023;114(2):381-392.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC