Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Collagen Hyrolysate Chocolate Flavored Ingredients & Drug Interactions

by Great Lakes Gelatin Co.

Collagen Hyrolysate Chocolate Flavored label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Collagen Hyrolysate Chocolate Flavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Collagen Hyrolysate Chocolate Flavored is a dietary supplement by Great Lakes Gelatin Co. with 3 active ingredients. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stevia leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Collagen Hyrolysate Chocolate Flavored by Great Lakes Gelatin Co.

Ask about any prescription or over-the-counter medication and we check it for interactions with Collagen Hyrolysate Chocolate Flavored by Great Lakes Gelatin Co. — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Collagen Hyrolysate Chocolate Flavored by Great Lakes Gelatin Co.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder has two active ingredients. Collagen peptides are broken-down collagen proteins — a structural protein from animal sources — that your body uses as a dietary protein.

Stevia leaf extract is a sweetener derived from the stevia plant, used here to flavor the chocolate powder without added sugar. The product also contains natural flavor and monk fruit as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Joint, bone, skin and hair health.
  • We looked for evidence on: Joint pain, Knee pain, Osteoarthritis, Osteoporosis, Osteopenia, Aging skin — and 4 related terms.
  • The strongest evidence on file: Collagen Peptides is rated "Possibly Effective" for Aging skin (Natural Medicines).
  • Also on file: Collagen Peptides is rated "Insufficient Reliable Evidence To Rate" for Osteoporosis, Brittle nails, Osteoarthritis, Joint pain, and more.

Collagen peptides are possibly effective for aging skin and dry skin — meaning some clinical evidence supports the idea, though more research would help confirm it. The evidence for muscle strength is currently pointing toward it being possibly ineffective, and there isn't enough reliable data yet on acne or athletic performance.

Stevia's effectiveness for blood sugar control, blood pressure, and weight is not yet established in our data — the evidence is still insufficient to say whether it works for these uses.

The evidence, ingredient by ingredient Stevia Collagen Peptides

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Collagen peptides are generally well tolerated, with only mild and uncommon side effects like nausea, indigestion, diarrhea, or gas. Stevia and its compounds also appear well tolerated overall; most users don't report problems, and any minor effects — bloating, dizziness, headache, muscle pain, nausea, or numbness — tend to fade after the first week.

Allergic reactions are rare but possible. For pregnancy, there isn't enough safety data on collagen peptides to know either way — talk with your doctor before using.

Stevia in the small amounts found in typical foods is generally recognized as safe, but high-dose supplement use hasn't been well studied in pregnancy or breastfeeding, so caution is advised in both cases. If you're pregnant or nursing, check with your pharmacist for personalized guidance.

Side effects, ingredient by ingredient Stevia Collagen Peptides

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Stevia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check your medications against these interactions: lithium (Moderate severity) — stevia may raise lithium levels; blood pressure medications (Minor severity) — stevia may enhance their effect; and diabetes medications (Minor severity) — stevia may increase low blood sugar risk. If any of these apply to you, talk to your pharmacist first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This collagen powder is a straightforward protein supplement with a stevia sweetener, generally well tolerated and possibly helpful for skin aging or dryness. If you take lithium, blood pressure medications, or diabetes medications, you'll want to check with your pharmacist first — stevia can interact with these drugs.

Pregnant or nursing mothers should also run this past their doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Collagen Hyrolysate Chocolate Flavored, straight from the product label.

Brand Great Lakes Gelatin Co.
Barcode (UPC) 322654002835
Net contents 10 Ounce(s); 283 Gram(s)
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 298582
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Collagen Hyrolysate Chocolate Flavored by Great Lakes Gelatin Co., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
13 Gram(s)
Maximum serving Sizes:
13 Gram(s)
Servings per container
22
UPC/BARCODE
322654002835
IngredientAmount% DV
Calories50 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Protein11 Gram(s)--
Stevia leaf extract40 mg--
Collagen Peptides12 Gram(s)--

Other ingredients: Natural flavor, Monk Fruit

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

We've been at it since 1922, so we know a thing or two about making great collagen products. Our high-quality ingredients - grass fed collagen, botanically-sourced colors and flavors - dissolve quickly and are easy to digest. Put a little flavor in your day, your way! Grass fed

Gluten-free No preservatives Glyphosate free

Hot or cold liquid soluble

Quick dissolve Daily Wellness Maintains healthy hair Promotes healthy skin and nails Supports joint health

Variations in color, odor, taste and solubility may occur.

Formula

Types I & III Collagen

Kosher Kosher Supervisory Services USA Europe Asia Pareve

Chocolate flavored with other natural flavors 12g Collagen per serving Type I & III collagen

Seals/Symbols

Kosher Supervisory Services USA Europe Asia Pareve

Satisfaction Guarantee

Suggested/Recommended/Usage/Directions

Directions: Add 2 scoops to your favorite beverage or recipe. For best results use daily. Just mix in and enjoy!

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Join the conversation! Facebook Instagram Pinterest @greatlakeswellness #GreatLakesGreatYou

New look Same great product

Typical amino acid content per serving Alanine 1032 mg Leucine 324 mg Arginine 876 mg Lysine 432 mg Aspartic acid 696 mg Methionine 108 mg Cystine 0 mg Phenylalanine 252 mg Glutamic acid 1224 mg Proline 1512 mg Glycine 2652 mg Serine 384 mg Histidine 120 mg Threonine 216 mg Hydroxylysine 192 mg Tryptophan 0 mg Hydroxyproline 1428 mg Tyrosine 96 mg Isoleucine 168 mg Valine 288 mg Natural variations may occur Essential amino acids

Product is packaged by weight not volume, settling will occur.

Storage

Store dry & do not refrigerate

Brand IP Statement(s)

Great Lakes Wellness Trusted since 1922 Heritage

FDA Statement of Identity

Dietary Supplement

Precautions

Notices: Collagen protein does not count toward the FDA recommended Percent Daily Value for protein. Do not use if top seal is torn or punctured. Use this product as a food supplement only. Do not use for weight reduction.

If you are pregnant, nursing or have a medical condition, consult your physician before use.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Collagen Hyrolysate Chocolate Flavored by Great Lakes Gelatin Co. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Collagen Hyrolysate Chocolate Flavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Collagen Hyrolysate Chocolate Flavored by Great Lakes Gelatin Co.

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size13 Gram(s) Dosage formPowder Servings per container22 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

11 Gram(s) per serving

Stevia leaf extract

Interacts with
259 drugs
40 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Stevia leaf extract monograph & interactions

Collagen Peptides

No known
interactions
12 Gram(s) per serving Form: Bovine

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is...

Collagen Peptides monograph & interactions

Other (inactive) ingredients: Natural flavor, Monk Fruit. These complete the product’s ingredient list but are not active constituents.

Interaction report

Collagen Hyrolysate Chocolate Flavored by Great Lakes Gelatin Co. Drug Interactions

Want to check YOUR meds against Collagen Hyrolysate Chocolate Flavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
1 Moderate 258 Minor

Ingredients driving the most interactions

Stevia leaf extract 259

Individual Drug Interactions

The ingredients in Collagen Hyrolysate Chocolate Flavored interact with 259 drugs. Click any drug to see the details.

1 of the 3 ingredients in Collagen Hyrolysate Chocolate Flavored interact with drugs. Each result below shows which ingredient is responsible. Stevia leaf extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Collagen Hyrolysate Chocolate Flavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Stevia leaf extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
Stevia leaf extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Collagen Hyrolysate Chocolate Flavored, from the product label.

Great Lakes Gelatin Co.

See all Great Lakes Gelatin Co. products
Name
Great Lakes Wellness Company, LLC
Street Address
253 Commerce Drive
City
Grayslake
State
IL
ZipCode
60030
Phone Number
847-223-8141
Web Address
www.GreatLakesWellness.com
Pharmacist Counseling Corner

Collagen Hyrolysate Chocolate Flavored by Great Lakes Gelatin Co.: Common Questions

Does Collagen Hyrolysate Chocolate Flavored by Great Lakes Gelatin Co. interact with any medications?
Yes. Based on its ingredients, Collagen Hyrolysate Chocolate Flavored has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Collagen Hyrolysate Chocolate Flavored contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with wrinkles or dry skin?
Collagen peptides show possibly effective evidence for both aging skin and dry skin. That means some clinical research backs the idea, though we'd benefit from more studies. Results vary person to person.
What are the side effects?
Collagen peptides rarely cause mild stomach upset like nausea or gas. Stevia may cause bloating, dizziness, headache, muscle pain, nausea, or numbness — but these are uncommon and usually fade after the first week. Allergic reactions are rare.
Is it safe if I'm pregnant or breastfeeding?
There isn't enough safety data on collagen peptides during pregnancy or breastfeeding to say either way. Stevia in food amounts is generally recognized as safe, but high-dose supplement doses haven't been well studied in these situations. Talk with your doctor or pharmacist before using if you're pregnant or nursing.
Why do I need to check with my pharmacist?
Stevia in this product can interact with lithium (a mood stabilizer), blood pressure medications, and diabetes medications. Depending on what you take, those interactions could be serious. Your pharmacist can let you know if it's safe for your specific medications.
What is stevia, and why is it in this product?
Stevia is a natural sweetener extracted from the stevia plant — it's used here to flavor the chocolate powder without adding sugar. Purified stevia in typical food amounts is generally recognized as safe, though high-dose supplements haven't been as thoroughly studied.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Collagen Hyrolysate Chocolate Flavored is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Collagen Hyrolysate Chocolate Flavored label
Go deeper

The Full Monographs Behind Collagen Hyrolysate Chocolate Flavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph → Herb & supplement monograph

Collagen Peptides

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is still developing and results vary. They...

Read the full Collagen Peptides monograph →
Sources

Sources & How We Checked

Collagen Hyrolysate Chocolate Flavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Collagen Peptides 2 references
  1. Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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