Interactions on record — worth a quick check against your medications. Based on 4 of 5 ingredients. Check your meds →
Dietary supplement

Collagen Peptides Mixed Berry Ingredients & Drug Interactions

by Vital Proteins

Collagen Peptides Mixed Berry label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Collagen Peptides Mixed Berry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Collagen Peptides Mixed Berry is a dietary supplement by Vital Proteins with 5 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 423 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin C, Sodium, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Collagen Peptides Mixed Berry by Vital Proteins

Ask about any prescription or over-the-counter medication and we check it for interactions with Collagen Peptides Mixed Berry by Vital Proteins — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Collagen Peptides Mixed Berry by Vital Proteins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder has 4 active ingredients: collagen peptides (the main protein), sodium, vitamin C, and potassium. Collagen peptides are broken-down collagen — a structural protein your body uses in skin, joints, and connective tissue.

The product also contains berry and acerola cherry powders as flavoring and color, but these are inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: skin hydration, elasticity, joints and bones.
  • We looked for evidence on: Aging skin, Atrophic acne scars, Brittle nails, Cellulite, Dermatoporosis, Dry skin — and 4 related terms.
  • The strongest evidence on file: Collagen Peptides is rated "Possibly Effective" for Aging skin (Natural Medicines).
  • Also on file: Collagen Peptides is rated "Possibly Effective" for Dry skin.
  • Also on file: Vitamin C is rated "Possibly Ineffective" for Fractures.

Evidence supports collagen peptides for aging and dry skin — the data rates it possibly effective for both. For muscle strength, the evidence suggests it may not help.

We don't have enough reliable data to rate it for acne or athletic performance. Vitamin C is effective for vitamin C deficiency and possibly effective for anemia of chronic disease, cataracts, atrial fibrillation, and exercise-related respiratory infections.

Sodium and potassium aren't rated for effectiveness in this product's context — they're minerals your body needs in balanced amounts, not therapeutic ingredients.

The evidence, ingredient by ingredient Sodium Vitamin C Potassium Collagen Peptides

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Collagen peptides are generally well tolerated; nausea, indigestion, diarrhea, and bloating are rare. Sodium is safe at normal dietary amounts but too much is linked to high blood pressure and heart strain — avoid sodium supplements or very high intake without talking to your doctor.

Vitamin C is generally safe at normal doses but can cause stomach cramps, heartburn, diarrhea, nausea, and headache at doses above 2 grams daily; kidney stones have been reported in people prone to them. Potassium from food is fine, but supplements can raise blood levels to dangerous heights, especially in people with kidney disease.

For pregnancy, collagen peptides have not been well studied — check with your doctor. Vitamin C at normal doses is likely safe in pregnancy, but high-dose supplements may be unsafe.

Potassium from diet is likely safe in pregnancy, but only use supplements under medical guidance.

Side effects, ingredient by ingredient Sodium Vitamin C Potassium Collagen Peptides

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Potassium, Vitamin C, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments; lithium.
  • For scale: 423 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking this product if you use blood pressure medications (especially ACE inhibitors, ARBs, or antihypertensive drugs), potassium-sparing diuretics, blood thinners like warfarin, thyroid medication (levothyroxine), estrogen-based birth control or hormone therapy, or chemotherapy drugs. The sodium and potassium in this product can affect how these medications work or raise blood mineral levels to unsafe heights.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a collagen-protein powder with berries and added vitamins and minerals. If you take blood pressure medication, a blood thinner, thyroid medication, estrogen-based birth control, or potassium-sparing water pills, or if you have kidney disease, check your medications with the tool below before starting.

Anyone else should talk with their pharmacist if they're pregnant, breastfeeding, or on any regular prescription.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Collagen Peptides Mixed Berry, straight from the product label.

Brand Vital Proteins
Barcode (UPC) 850232005881
Net contents 10.4 Ounce(s); 295 Gram(s)
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 302857
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Collagen Peptides Mixed Berry by Vital Proteins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
29 Gram(s)
Maximum serving Sizes:
29 Gram(s)
Servings per container
10
UPC/BARCODE
850232005881
IngredientAmount% DV
Calories100 Calorie(s)--
Total Carbohydrates7 Gram(s)3%
Sodium110 mg5%
Vitamin C60 mg67%
Potassium130 mg3%
Total Sugars5 Gram(s)--
Protein18 Gram(s)--
Collagen Peptides20 Gram(s)--

Other ingredients: Blueberry, Powder, Strawberry, Powder, Blackberry, Powder, Raspberry, Powder, Acerola Cherry Juice, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Our flavored Collagen Peptides is the perfect way to elevate your water, smoothie, dessert & other recipes.

Mix in Cold Liquids

Directions: Combine 1 scoop with 8 fl oz of liquid, mix thoroughly.

Formula

Made with collagen and a fruit-forward blend, our Mixed Berry Collagen Peptides boosts your wellness routine with every scoop.

20g Collagen Peptides Natural Electrolytes per serving

Paleo Friendly

20g Collagen per Serving

K Kosher

Made With Bovine Collagen Peptides

General Statements

Packaged by weight, not volume. Settling may occur. Fill Line

For illustrative purposes only, does not contain whole fruit.

Typical Amino Acid Profile (Average milligrams per serving naturally occurring) Alanine 1,462 mg Arginine 1,517 mg Aspartic Acid 1,192 mg Glutamic Acid 2,239 mg Glycine 3.719 mg Histidine 144 mg Essential Amino Acids Hydroxylysine 217 mg Hydroxyproline 2,058 mg Isoleucine 271 mg Essential Amino Acids Leucine 524 mg Essential Amino Acids Lysine 614 mg Essential Amino Acids Methionine 108 mg Essential Amino Acids Phenylalanine 379 mg Essential Amino Acids Proline 2,076 mg Serine 614 mg Threonine 343 mg Essential Amino Acids Tryptophan 0 mg Essential Amino Acids Tyrosine 90 mg Valine 433 mg Essential Amino Acids Contains 8 of 9 Essential Amino Acids

Recycle 2 HDPE BPA-free

Formulation

Youthful Appearance Skin Hydration Skin Elasticity Healthy Joints & Bones Hair & Nail Support

Skin, Hair, Nail + Joint Support Grass Fed + Pasture Raised

Dairy Free Gluten Free

Look & Feel Your Best

Brand IP Statement(s)

#stayvital

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Notice: Use this product as a food supplement only. Do not use for weight reduction.

This product is manufactured in a facility that processes milk, fish and tree nuts.

If you are pregnant, nursing or have a medical condition, consult your physician before use.

Do not use if safety seal is broken or missing.

FDA Statement of Identity

Dietary Supplement

Storage

Storage Information: Store in a cool, dry place

Seals/Symbols

K Kosher Whole30 Approved

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Collagen Peptides Mixed Berry by Vital Proteins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Collagen Peptides Mixed Berry label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Collagen Peptides Mixed Berry by Vital Proteins

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size29 Gram(s) Dosage formPowder Servings per container10 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sodium

Interacts with
205 drugs
110 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Vitamin C

Interacts with
207 drugs
60 mg per serving

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...

Vitamin C monograph & interactions

Potassium

Interacts with
62 drugs
130 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Protein

18 Gram(s) per serving

Collagen Peptides

No known
interactions
20 Gram(s) per serving Form: Bovine

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is...

Collagen Peptides monograph & interactions

Other (inactive) ingredients: Blueberry, Powder, Strawberry, Powder, Blackberry, Powder, Raspberry, Powder, Acerola Cherry Juice, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Collagen Peptides Mixed Berry by Vital Proteins Drug Interactions

Want to check YOUR meds against Collagen Peptides Mixed Berry?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
423Drugs
317 Moderate 106 Minor

Ingredients driving the most interactions

Vitamin C 207
Sodium 205
Potassium 62

Individual Drug Interactions

The ingredients in Collagen Peptides Mixed Berry interact with 423 drugs. Click any drug to see the details.

3 of the 5 ingredients in Collagen Peptides Mixed Berry interact with drugs. Each result below shows which ingredient is responsible. Vitamin C Sodium Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Collagen Peptides Mixed Berry with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin C13 drug types · 207 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Aluminum

Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.

Likelihood Probable Evidence B
Antitumor Antibiotics

Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Estrogens

Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.

Likelihood Probable Evidence B
Fluphenazine (Prolixin)

Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.

Likelihood Possible Evidence D
Indinavir (Crixivan)

Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.

Likelihood Probable Evidence B
Warfarin (Coumadin)

High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.

Likelihood Probable Evidence B
Aspirin

Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.

Likelihood Possible Evidence B
Choline Magnesium Trisalicylate (Trilisate)

Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Niacin

Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Salsalate (Disalcid)

Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Vitamin C full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Collagen Peptides Mixed Berry, from the product label.

Vital Proteins

See all Vital Proteins products
Name
Vital Proteins LLC
Street Address
3400 Wolf Road Ste. 200
City
Franklin Park
State
IL
ZipCode
60131
Web Address
vitalproteins.com
Pharmacist Counseling Corner

Collagen Peptides Mixed Berry by Vital Proteins: Common Questions

Does Collagen Peptides Mixed Berry by Vital Proteins interact with any medications?
Yes. Based on its ingredients, Collagen Peptides Mixed Berry has a known interaction with 423 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Collagen Peptides Mixed Berry contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this collagen powder actually help with wrinkles and skin?
The evidence says collagen peptides are possibly effective for aging skin and dry skin. That means some research supports it, but it's not proven as strongly as a medication would be. Results vary person to person.
Is it safe to take while pregnant?
Collagen peptides haven't been well studied in pregnancy — there just isn't enough data to know either way. Talk with your doctor or pharmacist about whether it's right for you. Vitamin C at normal doses is likely safe, but potassium from this product is likely safe too at dietary amounts.
Can I take this if I have high blood pressure?
That depends on which medication you take. If you're on a blood pressure drug, the sodium here could work against it and make your pressure harder to control. Run your exact medication through the checker on this page, and ask your pharmacist whether this product fits with your treatment plan.
What are the berry powders in here?
The product contains blueberry, strawberry, blackberry, raspberry, and acerola cherry powders for flavor and color. They're inactive ingredients — not the active part of the supplement.
Can I take this with my birth control pill?
Vitamin C in this product can increase estrogen levels from birth control, which might change how well it prevents pregnancy or how you feel on it. Check with your pharmacist or doctor — they can tell you whether the amount here matters for your specific pill.
Is there any collagen in this, or is it just marketing?
Yes, collagen peptides (hydrolyzed collagen) is the main active ingredient. It's real collagen broken down into smaller pieces so your body can absorb it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Collagen Peptides Mixed Berry label
Go deeper

The Full Monographs Behind Collagen Peptides Mixed Berry’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Vitamin C

Interacts with 207 drugs

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...

Read the full Vitamin C monograph → Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Collagen Peptides

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is still developing and results vary. They...

Read the full Collagen Peptides monograph →
Sources

Sources & How We Checked

Collagen Peptides Mixed Berry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 103 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
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Vitamin C 51 references
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Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
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  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Collagen Peptides 2 references
  1. Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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