Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

CoQ10 Complex Orange & Tropical Flavor Ingredients & Drug Interactions

by Spray For Life

CoQ10 Complex Orange & Tropical Flavor label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking CoQ10 Complex Orange & Tropical Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

CoQ10 Complex Orange & Tropical Flavor is a dietary supplement by Spray For Life with 3 active ingredients. Its ingredients are commonly taken for exercise performance and recovery, heart health, weight management.Based on those ingredients, 915 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin E, CoQ10, L-Carnitine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against CoQ10 Complex Orange & Tropical Flavor by Spray For Life

Ask about any prescription or over-the-counter medication and we check it for interactions with CoQ10 Complex Orange & Tropical Flavor by Spray For Life — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of CoQ10 Complex Orange & Tropical Flavor by Spray For Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 3 active ingredients. L-carnitine is an amino acid that plays a role in energy production and may help with carnitine deficiency; it's possibly effective for high cholesterol and heart-related conditions.

CoQ10 (coenzyme Q10) is a naturally occurring compound involved in cell energy; it's likely effective for CoQ10 deficiency and possibly effective for fibromyalgia, migraines, heart failure, and nerve damage from diabetes. Vitamin E is a fat-soluble antioxidant; it's effective for vitamin E deficiency and certain rare genetic conditions, and possibly effective for Alzheimer disease and other conditions.

The liquid is delivered in a spray form and contains inactive ingredients including vegetable glycerin, citric acid, potassium sorbate, stevia, and natural orange cream and tropical flavors.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: L-carnitine deficiency — rated "Effective" (L-carnitine) (Natural Medicines).
  • On file: Vitamin E deficiency — rated "Effective" (Vitamin E) (Natural Medicines).
  • On file: Ataxia with vitamin E deficiency (AVED) — rated "Effective" (Vitamin E) (Natural Medicines).
  • On file: Coenzyme Q10 deficiency — rated "Likely Effective" (Coenzyme Q10) (Natural Medicines).
  • On file: Alzheimer disease — rated "Possibly Effective" (Vitamin E) (Natural Medicines).

L-carnitine is effective for treating carnitine deficiency and possibly effective for lowering cholesterol and improving symptoms of congestive heart failure and angina. CoQ10 is likely effective for replacing a CoQ10 deficiency and possibly effective for fibromyalgia, migraines, congestive heart failure, and diabetic nerve damage.

Vitamin E is effective for vitamin E deficiency and a rare genetic condition (ataxia with vitamin E deficiency) and possibly effective for Alzheimer disease, beta-thalassemia, and G6PD deficiency. For other uses not listed here, the evidence is not established in the data we hold.

The evidence, ingredient by ingredient L-carnitine Coenzyme Q10 Vitamin E

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-carnitine and CoQ10 are generally well tolerated at typical doses. The most common side effects of both are gastrointestinal—stomach upset, nausea, diarrhea, heartburn—though these are uncommon.

L-carnitine can cause a fishy body odor at high doses, and rarely, seizures have been reported. Vitamin E is also generally well tolerated, with rare gastrointestinal side effects, headache, dizziness, and insomnia reported.

At high doses, vitamin E raises concerns about increased bleeding risk. Pregnancy and breastfeeding data are limited.

For L-carnitine, there is not enough reliable safety information for pregnancy; discuss with your doctor before use. L-carnitine is possibly safe while breastfeeding, though data are limited.

For CoQ10, pregnancy data are insufficient; the label advises caution during breastfeeding. Vitamin E from food and prenatal vitamins is appropriate in pregnancy, but avoid high-dose supplements unless your doctor directs otherwise.

During breastfeeding, normal dietary amounts are fine, but check with your doctor before high-dose supplements. Talk with your doctor or pharmacist about your individual situation.

Side effects, ingredient by ingredient L-carnitine Coenzyme Q10 Vitamin E

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Coenzyme Q10, Vitamin E, L-carnitine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; cancer treatments.
  • For scale: 916 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you use blood thinners (warfarin, acenocoumarol, or other anticoagulants or antiplatelet drugs)—all three ingredients may increase bleeding risk or reduce the drug's effectiveness. Also double-check if you take thyroid hormone replacement (L-carnitine may reduce its effectiveness), blood pressure medications (CoQ10 may lower pressure further), chemotherapy drugs, cyclosporine, or drugs metabolized by liver enzyme CYP3A4.

These are the medication types with documented interactions; discuss your exact medications with your own doctor or pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you have a deficiency in L-carnitine or CoQ10, or if you're interested in possibly boosting heart health or reducing migraines—but the ingredient list carries multiple medication interactions, most importantly with blood thinners and chemotherapy drugs. If you take warfarin, other anticoagulants, blood pressure medications, thyroid replacement, or chemotherapy, talk with your doctor or pharmacist before starting.

The same goes if you're pregnant, breastfeeding, or considering high-dose supplementation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CoQ10 Complex Orange & Tropical Flavor, straight from the product label.

Brand Spray For Life
Barcode (UPC) 689407108085
Net contents 0.88 fl. Oz.; 26 mL
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 176279
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CoQ10 Complex Orange & Tropical Flavor by Spray For Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.042 mL
Maximum serving Sizes:
0.042 mL
Servings per container
30
UPC/BARCODE
689407108085
IngredientAmount% DV
L-Carnitine50 mg--
CoQ1025 mg--
Vitamin E13 IU43%

Other ingredients: deionized Water, Vegetable Glycerin, Citric Acid, Potassium Sorbate, Stevia, natural Orange Cream flavor, natural Tropical flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

To use: Shake well, then press actuator down 3 or more times to prime pump. Suggested use: As a dietary supplement, (3) sprays twice daily. Spray into your mouth under the tongue, hold for 20 seconds and then swallow.

30 day supply, taken twice daily

Formula

Discussion: Each pre-metered, non-aerosol spray, delivers an active source of Coenyzme Q10, Vitamin E and L-Carnitne.

Brand IP Statement(s)

This patented NanoMist delivery system is intended to maximize the absorption of essential vitamins and nutrients.

1997-2016 All Rights Reserved

Patent #6,861,066

Patented NanoSyzed Absorption Process

NanoSynergy inside

Precautions

Keep out of reach of children

Caution: Do not spray in eyes.

Formulation

All Sprayforlife products are free of sugar, salt, corn, wheat, yeast, milk derivatives, artificial preservatives, colors and flavors, fillers and binders, soy and peanut products as well as GMO's.

Contains no fruit juice

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Made in the USA

USP standards

Seals/Symbols

USA

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

CoQ10 Complex Orange & Tropical Flavor by Spray For Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

CoQ10 Complex Orange & Tropical Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in CoQ10 Complex Orange & Tropical Flavor by Spray For Life

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.042 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Carnitine

Interacts with
19 drugs
50 mg per serving

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most...

L-Carnitine monograph & interactions

CoQ10

Interacts with
198 drugs
25 mg per serving Form: Ubiquinone

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

CoQ10 monograph & interactions

Vitamin E

Interacts with
764 drugs
13 IU per serving Form: Tocophersolan

Vitamin E is an essential fat-soluble vitamin and antioxidant that most people get in adequate amounts from a normal diet. Supplements can help correc...

Vitamin E monograph & interactions

Other (inactive) ingredients: Deionized Water, Vegetable Glycerin, Citric Acid, Potassium Sorbate, Stevia, Natural Orange Cream flavor, Natural Tropical flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

CoQ10 Complex Orange & Tropical Flavor by Spray For Life Drug Interactions

Want to check YOUR meds against CoQ10 Complex Orange & Tropical Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
915Drugs
776 Moderate 139 Minor

Ingredients driving the most interactions

Vitamin E 764
CoQ10 198
L-Carnitine 19

Individual Drug Interactions

The ingredients in CoQ10 Complex Orange & Tropical Flavor interact with 915 drugs. Click any drug to see the details.

3 of the 3 ingredients in CoQ10 Complex Orange & Tropical Flavor interact with drugs. Each result below shows which ingredient is responsible. Vitamin E CoQ10 L-Carnitine

Each ingredient & the kinds of drugs it affects

For each ingredient in CoQ10 Complex Orange & Tropical Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin E8 drug types · 764 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin E might reduce the effectiveness of alkylating agents.
There's concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin E have on chemotherapy. Advise patients to consult their oncologist before using vitamin E supplements, especially in high doses.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Concomitant use of vitamin E and anticoagulant or antiplatelet agents might increase the risk of bleeding.
Vitamin E seems to inhibit of platelet aggregation and antagonize the effects of vitamin K-dependent clotting factors. These effects appear to be dose-dependent, and are probably only likely to be clinically significant with doses of at least 800 units daily. Mixed tocopherols, such as those found in food, might have a greater antiplatelet effect than alpha-tocopherol. RRR alpha-tocopherol (natural vitamin E) 1000 IU daily antagonizes vitamin K-dependent clotting factors. Advise patients to avoid high doses of vitamin E, especially in people with low vitamin K intake or other risk factors for bleeding.

Likelihood Possible Evidence B
Antitumor Antibiotics

Theoretically, antioxidant effects of vitamin E might reduce the effectiveness of antitumor antibiotics.
There's concern that antioxidants could reduce the activity of antitumor antibiotic drugs such as doxorubicin, which generate free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin E have on chemotherapy involving antitumor antibiotics. Advise patients to consult their oncologist before using vitamin E supplements, especially in high doses.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

A specific form of vitamin E might increase absorption and levels of cyclosporine.
There is some evidence that one specific formulation of vitamin E (D-alpha-tocopheryl-polyethylene glycol-1000 succinate, TPGS, tocophersolan, Liqui-E) might increase absorption of cyclosporine. This vitamin E formulation forms micelles which seems to increase absorption of cyclosporine by 40% to 72% in some patients. However, this interaction is unlikely to occur with the usual forms of vitamin E.

Likelihood Unlikely Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, vitamin E might induce metabolism of CYP3A4, possibly reducing the levels CYP3A4 substrates.
Vitamin E appears to bind with the nuclear receptor, pregnane X receptor (PXR), which results in increased expression of CYP3A4. Although the clinical significance of this is not known, use caution when considering concomitant use of vitamin E and other drugs affected by these enzymes.

Likelihood Possible Evidence D
Selumetinib (Koselugo)

Taking selumetinib with vitamin E can result in a total daily dose of vitamin E that exceeds safe limits and therefore might increase the risk of bleeding.
Selumetinib contains 48-54 IU vitamin E per capsule. The increased risk of bleeding with vitamin E appears to be dose-dependent. Be cautious when using selumetinib in combination with supplemental vitamin E, especially in patients at higher risk of bleed, such as those with chronic conditions and those taking antiplatelet drugs.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Using vitamin E with warfarin might increase the risk of bleeding.
Due to interference with production of vitamin K-dependent clotting factors, use of more than 400 IU of vitamin E daily with warfarin might increase prothrombin time (PT), INR, and the risk of bleeding,. At a dose of 1000 IU per day, vitamin E can antagonize vitamin K-dependent clotting factors even in people not taking warfarin. Limited clinical evidence suggests that doses up to 1200 IU daily may be used safely by patients taking warfarin, but this may not be applicable in all patient populations.

Likelihood Possible Evidence B
Niacin

Vitamin E might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises high-density lipoprotein (HDL) cholesterol levels in people with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50%. Vitamin E alone combined with a statin does not seem to decrease HDL levels. It is not known whether the adverse effect on HDL is due to one of the other antioxidants or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Vitamin E full monograph & interactions

CoQ103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
CoQ10 full monograph & interactions

L-Carnitine3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.

Likelihood Possible Evidence D
L-Carnitine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for CoQ10 Complex Orange & Tropical Flavor, from the product label.

Spray For Life

See all Spray For Life products
Name
NanoSynergy Worldwide, Inc.
City
Reno
State
Nevada
Phone Number
1-877-679-6266
Web Address
www.sprayforlife.com
Pharmacist Counseling Corner

CoQ10 Complex Orange & Tropical Flavor by Spray For Life: Common Questions

Does CoQ10 Complex Orange & Tropical Flavor by Spray For Life interact with any medications?
Yes. Based on its ingredients, CoQ10 Complex Orange & Tropical Flavor has a known interaction with 915 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CoQ10 Complex Orange & Tropical Flavor contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-carnitine, and why is it in this product?
L-carnitine is an amino acid your body needs to turn fat into energy. It's included because it's effective for people with L-carnitine deficiency and possibly helpful for high cholesterol and heart conditions like heart failure and angina.
What does CoQ10 do?
CoQ10 is a compound your cells use to produce energy and it acts as an antioxidant. It's likely to help if you're low in CoQ10 and possibly beneficial for migraines, fibromyalgia, heart failure, and nerve damage from diabetes.
Can I take this while pregnant?
There isn't enough reliable safety data for L-carnitine or CoQ10 in pregnancy. Vitamin E from food and prenatal vitamins is fine, but avoid high-dose supplements without your doctor's approval. Talk with your doctor or pharmacist about whether this product is right for you.
What are the most common side effects?
The most frequent side effects are gastrointestinal—nausea, stomach upset, diarrhea, and heartburn—though these occur in less than 1% of people at typical doses. L-carnitine can cause a fishy body odor at higher doses.
Is this product safe if I'm breastfeeding?
L-carnitine is possibly safe while breastfeeding but data are limited. CoQ10 and vitamin E have insufficient or limited safety data; check with your doctor or pharmacist before taking this product while breastfeeding.
Can this product interfere with chemotherapy?
Yes. Both CoQ10 and vitamin E have antioxidant effects that theoretically may reduce the activity of certain chemotherapy drugs, especially those that work by generating free radicals. If you're undergoing cancer treatment, talk with your oncologist before starting this supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CoQ10 Complex Orange & Tropical Flavor label
Go deeper

The Full Monographs Behind CoQ10 Complex Orange & Tropical Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

L-carnitine

Interacts with 19 drugs

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...

Read the full L-carnitine monograph → Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph → Herb & supplement monograph

Vitamin E

Interacts with 764 drugs

Vitamin E is an essential fat-soluble vitamin and antioxidant that most people get in adequate amounts from a normal diet. Supplements can help correct a true deficiency, but high-dose vitam...

Read the full Vitamin E monograph →
Sources

Sources & How We Checked

CoQ10 Complex Orange & Tropical Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 145 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-carnitine 41 references
  1. Ellaway CM, Williams K, Leonard H, et al. Rett syndrome: randomized controlled trial of L-carnitine. J Child Neurol 1999;14:162-7. PubMed
  2. Anon. Carnitor (levocarnitine) package insert. Sigma-Tau Pharmaceuticals Inc, Gaithersburg, MD. December 1999.
  3. Cherchi A, Lai C, Angelino F, et al. Effects of L-carnitine on exercise tolerance in chronic stable angina: a multicenter, double-blind, randomized, placebo-controlled, crossover study. Int J Clin Pharmacol Ther Toxicol 1985;23:569-72.
  4. Plioplys AV, Plioplys S. Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome. Neuropsychobiology 1997;35:16-23. PubMed
  5. Benvenga S, Ruggeri RM, Russo A, et al. Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. J Clin Endocrinol Meta
  6. Martinez E, Domingo P, Roca-Cusachs A. Potentiation of acenocoumarol action by L-carnitine. J Intern Med 1993;233:94.
  7. Bachmann HU, Hoffmann A. Interaction of food supplement L-carnitine with oral anticoagulant acenocoumarol. Swiss Med Wkly 2004;134:385. PubMed
  8. Evans AM, Fornasini G. Pharmacokinetics of L-carnitine. Clin Pharmacokinet 2003;42:941-67. PubMed
  9. 12761 Benvenga S, Amato A, Calvani M, Trimarchi F. Effects of carnitine on thyroid hormone action. Ann N Y Acad Sci 2004;1033:158-67. PubMed
  10. Ciacci C, Peluso G, Iannoni E, et al. L-Carnitine in the treatment of fatigue in adult celiac disease patients: a pilot study. Dig Liver Dis 2007;39:922-8. PubMed
  11. Cruciani RA, Dvorkin E, Homel P, et al. Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study. J Pain Symptom Manage 2006;32:551-9. PubMed
  12. Lebrun C, Alchaar H, Candito M, et al. Levocarnitine administration in multiple sclerosis patients with immunosuppressive therapy-induced fatigue. Mult Scler 2006;12:321-4. PubMed
  13. Malaguarnera M, Cammalleri L, Gargante MP, et al. L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial. Am J Clin Nutr 2007;86:1738-44. PubMed
  14. Mantovani G, Maccio A, Madeddu C, et al. Randomized phase III clinical trial of five different arms of treatment in 322 patients with cancer cachexia. Oncologist 2010;15:200-11.
  15. Angelova-Fischer I, Rippke F, Fischer TW, Neufang G, Zillikens D. A double-blind, randomized, vehicle-controlled efficacy assessment study of a skin care formulation for improvement of mild to moderately severe acne. J Eur Acad Dermatol Venereol. 2013 Jul PubMed
  16. Hatamkhani S, Khalili H, Karimzadeh I, Dashti-Khavidaki S, Abdollahi A, Jafari S. Carnitine for prevention of antituberculosis drug-induced hepatotoxicity: a randomized, clinical trial. J Gastroenterol. Hepatol. 2014 May;29(5):997-1004. PubMed
  17. Boehm G, Stahl B. Oligosaccharides from milk. J Nutr 2007;137(3 Suppl 2):847S-849S.
  18. Van Oudheusden, L. J. and Scholte, H. R. Efficacy of carnitine in the treatment of children with attention-deficit hyperactivity disorder. Prostaglandins Leukot.Essent.Fatty Acids 2002;67(1):33-38. PubMed
  19. Derosa, G., Cicero, A. F., Gaddi, A., Mugellini, A., Ciccarelli, L., and Fogari, R. The effect of L-carnitine on plasma lipoprotein(a) levels in hypercholesterolemic patients with type 2 diabetes mellitus. Clin Ther 2003;25(5):1429-1439. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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