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Dietary supplement

CoQ10 with L-Carnitine Ingredients & Drug Interactions

by Mason Natural

CoQ10 with L-Carnitine label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking CoQ10 with L-Carnitine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

CoQ10 with L-Carnitine is a dietary supplement by Mason Natural with 3 active ingredients. Its ingredients are commonly taken for exercise performance and recovery, heart health, weight management.Based on those ingredients, 915 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin E, Coenzyme Q10, L-Carnitine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against CoQ10 with L-Carnitine by Mason Natural

Ask about any prescription or over-the-counter medication and we check it for interactions with CoQ10 with L-Carnitine by Mason Natural — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of CoQ10 with L-Carnitine by Mason Natural

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Mason Natural's CoQ10 with L-Carnitine contains 3 active ingredients. L-Carnitine is an amino acid that plays a role in energy metabolism and heart function.

Coenzyme Q10 (CoQ10) is a naturally occurring compound that acts as an antioxidant and supports cellular energy production. Vitamin E is a fat-soluble antioxidant.

The product also includes inactive ingredients such as rice bran oil, gelatin, glycerin, sorbitol, purified water, yellow beeswax, soy lecithin, natural caramel color, and titanium dioxide, which serve as the capsule and delivery system.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support cardiovascular health.
  • We looked for evidence on: Cardiovascular disease (CVD), Coronary heart disease (CHD), Congestive heart failure (CHF), Arrhythmia, Atrial fibrillation, Angina — and 4 related terms.
  • The strongest evidence on file: Coenzyme Q10 is rated "Possibly Effective" for Congestive heart failure (CHF) (Natural Medicines).
  • Also on file: L-carnitine is rated "Possibly Effective" for Angina, Congestive heart failure (CHF).
  • Also on file: Vitamin E is rated "Possibly Ineffective" for Angina, Atherosclerosis, Congestive heart failure (CHF).

L-Carnitine is effective for L-carnitine deficiency and possibly effective for high cholesterol (hyperlipidemia), heart failure (congestive heart failure), and angina. Vitamin E is effective for vitamin E deficiency and ataxia caused by vitamin E deficiency (AVED), and possibly effective for Alzheimer disease, beta-thalassemia, G6PD deficiency, and intracranial hemorrhage.

CoQ10 is likely effective for CoQ10 deficiency and possibly effective for fibromyalgia, migraine headaches, heart failure, and diabetic nerve pain (diabetic neuropathy). The evidence base varies by ingredient and condition, so talk with your doctor about whether this combination is right for your specific health goals.

The evidence, ingredient by ingredient L-carnitine Vitamin E Coenzyme Q10

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

All three ingredients are generally well tolerated at typical doses. L-Carnitine can cause stomach upset (abdominal cramps, diarrhea, nausea, heartburn) and a fishy body odor at higher doses; seizures are rare but serious.

Vitamin E at usual dietary amounts is safe, but high-dose long-term supplements may increase bleeding risk. CoQ10 causes gastrointestinal side effects in less than 1% of users—appetite loss, diarrhea, nausea, heartburn—which can be reduced by dividing doses over 100 mg.

Headache, dizziness, and insomnia have been reported with CoQ10. Pregnancy safety for L-Carnitine is not established in the data we hold.

Vitamin E in amounts from food and prenatal vitamins is appropriate in pregnancy, but avoid high-dose supplements unless your doctor directs it. For CoQ10, there is not enough reliable safety data in pregnancy, so avoid it unless your doctor advises otherwise.

L-Carnitine's safety while breastfeeding is not well studied, so caution is advised. Vitamin E is likely safe in normal dietary amounts while breastfeeding but check with your doctor about high-dose supplements.

CoQ10's safety while breastfeeding has not been well studied—use caution and confirm with your doctor.

Side effects, ingredient by ingredient L-carnitine Vitamin E Coenzyme Q10

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Coenzyme Q10, Vitamin E, L-carnitine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; cancer treatments.
  • For scale: 916 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take any blood thinners (anticoagulants) or antiplatelet drugs such as warfarin or acenocoumarol—both L-Carnitine and CoQ10 interact with these, and vitamin E increases bleeding risk (Moderate severity). If you take thyroid hormone replacement, L-Carnitine may reduce its effectiveness (Moderate).

Chemotherapy drugs that generate free radicals (alkylating agents and antitumor antibiotics) may be less effective (Moderate). Blood pressure medications could have additive effects with CoQ10 (Minor).

Drugs metabolized by your liver's CYP3A4 pathway may have lower levels if you use vitamin E (Moderate). If you take niacin for cholesterol, vitamin E may reduce its HDL-raising benefits (Minor).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you have L-carnitine deficiency, heart issues, migraines, or high cholesterol and your doctor thinks a combination supplement is appropriate. Be cautious if you take blood thinners, thyroid medication, chemotherapy, or blood pressure medications—these warrant a conversation with your doctor or pharmacist before you start.

High-dose vitamin E raises bleeding concerns, especially with anticoagulants. Talk it over with your own doctor or pharmacist to make sure this combination fits your health picture and current medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CoQ10 with L-Carnitine, straight from the product label.

Brand Mason Natural
Barcode (UPC) 311845165992
Net contents 50 Softgel(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 244742
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CoQ10 with L-Carnitine by Mason Natural, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
50
UPC/BARCODE
311845165992
IngredientAmount% DV
Calories5 Calorie(s)1%
Total Fat0.5 Gram(s)1%
L-Carnitine250 mg--
Vitamin E34 mg230%
Coenzyme Q1030 mg--

Other ingredients: Rice Bran Oil, Gelatin, Glycerin, Sorbitol, purified Water, yellow Beeswax, Soy Lecithin, natural Caramel color, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Mason Guarantee Laboratory Tested cGMP Certified Good Manufacturing Practice

General Statements

N Mason Natural Est. 1967

Please recycle

Formulation

May support cardiovascular health

Guaranteed no added: Sugar, starch, corn, wheat, dairy, egg, fragrance, artificial flavors, preservatives.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults - Take one softgel daily, preferably with food, as a dietary supplement.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Allergen certification - This product contains soy.

Caution: If you are pregnant, nursing, taking any medications or have any medical condition, consult your physician before use.

Discontinue use and consult your physician if any adverse reactions occur.

Keep out of reach of children.

Tamper-evident seal: Do not use product if seal appears tampered.

Storage

Store in a dry place under controlled room temperature: 20 degrees - 25 degrees C (68 degrees - 77 degrees F).

Brand IP Statement(s)

Mason Natural is a registered trademark and does not refer to any product or ingredient claim.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

CoQ10 with L-Carnitine by Mason Natural label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

CoQ10 with L-Carnitine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in CoQ10 with L-Carnitine by Mason Natural

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Carnitine

Interacts with
19 drugs
250 mg per serving

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most...

L-Carnitine monograph & interactions

Vitamin E

Interacts with
764 drugs
34 mg per serving Form: DL-Alpha-Tocopheryl Acetate

Vitamin E is an essential fat-soluble vitamin and antioxidant that most people get in adequate amounts from a normal diet. Supplements can help correc...

Vitamin E monograph & interactions

Coenzyme Q10

Interacts with
198 drugs
30 mg per serving

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q10 monograph & interactions

Other (inactive) ingredients: Rice Bran Oil, Gelatin, Glycerin, Sorbitol, Purified Water, Yellow Beeswax, Soy Lecithin, Natural Caramel color, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

CoQ10 with L-Carnitine by Mason Natural Drug Interactions

Want to check YOUR meds against CoQ10 with L-Carnitine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
915Drugs
776 Moderate 139 Minor

Ingredients driving the most interactions

Vitamin E 764
Coenzyme Q10 198
L-Carnitine 19

Individual Drug Interactions

The ingredients in CoQ10 with L-Carnitine interact with 915 drugs. Click any drug to see the details.

3 of the 3 ingredients in CoQ10 with L-Carnitine interact with drugs. Each result below shows which ingredient is responsible. Vitamin E Coenzyme Q10 L-Carnitine

Each ingredient & the kinds of drugs it affects

For each ingredient in CoQ10 with L-Carnitine with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin E8 drug types · 764 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin E might reduce the effectiveness of alkylating agents.
There's concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin E have on chemotherapy. Advise patients to consult their oncologist before using vitamin E supplements, especially in high doses.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Concomitant use of vitamin E and anticoagulant or antiplatelet agents might increase the risk of bleeding.
Vitamin E seems to inhibit of platelet aggregation and antagonize the effects of vitamin K-dependent clotting factors. These effects appear to be dose-dependent, and are probably only likely to be clinically significant with doses of at least 800 units daily. Mixed tocopherols, such as those found in food, might have a greater antiplatelet effect than alpha-tocopherol. RRR alpha-tocopherol (natural vitamin E) 1000 IU daily antagonizes vitamin K-dependent clotting factors. Advise patients to avoid high doses of vitamin E, especially in people with low vitamin K intake or other risk factors for bleeding.

Likelihood Possible Evidence B
Antitumor Antibiotics

Theoretically, antioxidant effects of vitamin E might reduce the effectiveness of antitumor antibiotics.
There's concern that antioxidants could reduce the activity of antitumor antibiotic drugs such as doxorubicin, which generate free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin E have on chemotherapy involving antitumor antibiotics. Advise patients to consult their oncologist before using vitamin E supplements, especially in high doses.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

A specific form of vitamin E might increase absorption and levels of cyclosporine.
There is some evidence that one specific formulation of vitamin E (D-alpha-tocopheryl-polyethylene glycol-1000 succinate, TPGS, tocophersolan, Liqui-E) might increase absorption of cyclosporine. This vitamin E formulation forms micelles which seems to increase absorption of cyclosporine by 40% to 72% in some patients. However, this interaction is unlikely to occur with the usual forms of vitamin E.

Likelihood Unlikely Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, vitamin E might induce metabolism of CYP3A4, possibly reducing the levels CYP3A4 substrates.
Vitamin E appears to bind with the nuclear receptor, pregnane X receptor (PXR), which results in increased expression of CYP3A4. Although the clinical significance of this is not known, use caution when considering concomitant use of vitamin E and other drugs affected by these enzymes.

Likelihood Possible Evidence D
Selumetinib (Koselugo)

Taking selumetinib with vitamin E can result in a total daily dose of vitamin E that exceeds safe limits and therefore might increase the risk of bleeding.
Selumetinib contains 48-54 IU vitamin E per capsule. The increased risk of bleeding with vitamin E appears to be dose-dependent. Be cautious when using selumetinib in combination with supplemental vitamin E, especially in patients at higher risk of bleed, such as those with chronic conditions and those taking antiplatelet drugs.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Using vitamin E with warfarin might increase the risk of bleeding.
Due to interference with production of vitamin K-dependent clotting factors, use of more than 400 IU of vitamin E daily with warfarin might increase prothrombin time (PT), INR, and the risk of bleeding,. At a dose of 1000 IU per day, vitamin E can antagonize vitamin K-dependent clotting factors even in people not taking warfarin. Limited clinical evidence suggests that doses up to 1200 IU daily may be used safely by patients taking warfarin, but this may not be applicable in all patient populations.

Likelihood Possible Evidence B
Niacin

Vitamin E might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises high-density lipoprotein (HDL) cholesterol levels in people with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50%. Vitamin E alone combined with a statin does not seem to decrease HDL levels. It is not known whether the adverse effect on HDL is due to one of the other antioxidants or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Vitamin E full monograph & interactions

Coenzyme Q103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q10 full monograph & interactions

L-Carnitine3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.

Likelihood Possible Evidence D
L-Carnitine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for CoQ10 with L-Carnitine, from the product label.

Mason Natural

See all Mason Natural products
Name
Mason Vitamins, Inc.
City
Miami Lakes
State
FL
ZipCode
33014
Phone Number
1-888-860-5376
Web Address
www.MasonVitamins.com
Pharmacist Counseling Corner

CoQ10 with L-Carnitine by Mason Natural: Common Questions

Does CoQ10 with L-Carnitine by Mason Natural interact with any medications?
Yes. Based on its ingredients, CoQ10 with L-Carnitine has a known interaction with 915 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CoQ10 with L-Carnitine contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product have any ingredients I might be allergic to?
The product contains gelatin, soy lecithin, and beeswax as inactive ingredients, so if you're allergic to soy, shellfish, or bee products, check the label carefully or talk with your pharmacist. CoQ10 and L-Carnitine are generally well tolerated, though allergic rash and skin itching have been reported rarely with CoQ10.
What's L-Carnitine actually for?
L-Carnitine is an amino acid that helps your cells produce energy. It's effective for L-carnitine deficiency and possibly effective for heart failure, high cholesterol, and angina.
Can I take this if I'm pregnant?
Safety data during pregnancy is limited for L-Carnitine and CoQ10—there isn't enough reliable information to know either way. Vitamin E from food and prenatal vitamins is fine, but avoid high-dose supplements. Talk with your doctor or pharmacist for personalized advice before taking this product during pregnancy.
What side effects might I notice?
Stomach upset (nausea, diarrhea, heartburn, abdominal discomfort) is the most common issue, especially at higher doses of L-Carnitine or CoQ10. L-Carnitine can also cause a fishy body odor. CoQ10 may cause headache, dizziness, or insomnia. Side effects are usually mild and occur in a small number of people.
Is CoQ10 effective for heart health?
CoQ10 is likely effective if you have a CoQ10 deficiency and possibly effective for heart failure. It also may help with migraines and diabetic nerve pain. The evidence is strongest for deficiency; talk with your doctor about whether this product suits your specific heart condition.
Can I divide the dose to reduce stomach upset?
Yes—CoQ10 side effects can be minimized if daily doses above 100 mg are divided into smaller doses throughout the day rather than taken all at once.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CoQ10 with L-Carnitine label
Go deeper

The Full Monographs Behind CoQ10 with L-Carnitine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

L-carnitine

Interacts with 19 drugs

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...

Read the full L-carnitine monograph → Herb & supplement monograph

Vitamin E

Interacts with 764 drugs

Vitamin E is an essential fat-soluble vitamin and antioxidant that most people get in adequate amounts from a normal diet. Supplements can help correct a true deficiency, but high-dose vitam...

Read the full Vitamin E monograph → Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph →
Sources

Sources & How We Checked

CoQ10 with L-Carnitine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 145 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-carnitine 41 references
  1. Ellaway CM, Williams K, Leonard H, et al. Rett syndrome: randomized controlled trial of L-carnitine. J Child Neurol 1999;14:162-7. PubMed
  2. Anon. Carnitor (levocarnitine) package insert. Sigma-Tau Pharmaceuticals Inc, Gaithersburg, MD. December 1999.
  3. Cherchi A, Lai C, Angelino F, et al. Effects of L-carnitine on exercise tolerance in chronic stable angina: a multicenter, double-blind, randomized, placebo-controlled, crossover study. Int J Clin Pharmacol Ther Toxicol 1985;23:569-72.
  4. Plioplys AV, Plioplys S. Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome. Neuropsychobiology 1997;35:16-23. PubMed
  5. Benvenga S, Ruggeri RM, Russo A, et al. Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. J Clin Endocrinol Meta
  6. Martinez E, Domingo P, Roca-Cusachs A. Potentiation of acenocoumarol action by L-carnitine. J Intern Med 1993;233:94.
  7. Bachmann HU, Hoffmann A. Interaction of food supplement L-carnitine with oral anticoagulant acenocoumarol. Swiss Med Wkly 2004;134:385. PubMed
  8. Evans AM, Fornasini G. Pharmacokinetics of L-carnitine. Clin Pharmacokinet 2003;42:941-67. PubMed
  9. 12761 Benvenga S, Amato A, Calvani M, Trimarchi F. Effects of carnitine on thyroid hormone action. Ann N Y Acad Sci 2004;1033:158-67. PubMed
  10. Ciacci C, Peluso G, Iannoni E, et al. L-Carnitine in the treatment of fatigue in adult celiac disease patients: a pilot study. Dig Liver Dis 2007;39:922-8. PubMed
  11. Cruciani RA, Dvorkin E, Homel P, et al. Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study. J Pain Symptom Manage 2006;32:551-9. PubMed
  12. Lebrun C, Alchaar H, Candito M, et al. Levocarnitine administration in multiple sclerosis patients with immunosuppressive therapy-induced fatigue. Mult Scler 2006;12:321-4. PubMed
  13. Malaguarnera M, Cammalleri L, Gargante MP, et al. L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial. Am J Clin Nutr 2007;86:1738-44. PubMed
  14. Mantovani G, Maccio A, Madeddu C, et al. Randomized phase III clinical trial of five different arms of treatment in 322 patients with cancer cachexia. Oncologist 2010;15:200-11.
  15. Angelova-Fischer I, Rippke F, Fischer TW, Neufang G, Zillikens D. A double-blind, randomized, vehicle-controlled efficacy assessment study of a skin care formulation for improvement of mild to moderately severe acne. J Eur Acad Dermatol Venereol. 2013 Jul PubMed
  16. Hatamkhani S, Khalili H, Karimzadeh I, Dashti-Khavidaki S, Abdollahi A, Jafari S. Carnitine for prevention of antituberculosis drug-induced hepatotoxicity: a randomized, clinical trial. J Gastroenterol. Hepatol. 2014 May;29(5):997-1004. PubMed
  17. Boehm G, Stahl B. Oligosaccharides from milk. J Nutr 2007;137(3 Suppl 2):847S-849S.
  18. Van Oudheusden, L. J. and Scholte, H. R. Efficacy of carnitine in the treatment of children with attention-deficit hyperactivity disorder. Prostaglandins Leukot.Essent.Fatty Acids 2002;67(1):33-38. PubMed
  19. Derosa, G., Cicero, A. F., Gaddi, A., Mugellini, A., Ciccarelli, L., and Fogari, R. The effect of L-carnitine on plasma lipoprotein(a) levels in hypercholesterolemic patients with type 2 diabetes mellitus. Clin Ther 2003;25(5):1429-1439. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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