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Dietary supplement

Cordyceps 10:1 Mushroom Extract Ingredients & Drug Interactions

by Nootropics Depot

Cordyceps 10:1 Mushroom Extract label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cordyceps 10:1 Mushroom Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cordyceps 10:1 Mushroom Extract is a dietary supplement by Nootropics Depot with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cordyceps militaris 10:1 extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cordyceps 10:1 Mushroom Extract by Nootropics Depot

Ask about any prescription or over-the-counter medication and we check it for interactions with Cordyceps 10:1 Mushroom Extract by Nootropics Depot — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cordyceps 10:1 Mushroom Extract by Nootropics Depot

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: cordyceps militaris extract, concentrated at a 10:1 ratio (meaning 10 parts raw mushroom material reduced to 1 part extract). Cordyceps is a fungus traditionally used in herbal medicine and studied for potential effects on energy, athletic performance, and sexual function.

There are no inactive ingredients listed for this powder.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Cordyceps product and its label doesn't state a use — see Cordyceps's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for cordyceps is mixed and often inconclusive. For athletic performance, the data rates it as possibly ineffective — meaning available research doesn't support the claim that it boosts exercise capacity.

For sexual dysfunction, asthma, COPD, arrhythmia, and lung cancer, there isn't enough reliable evidence to say whether cordyceps works or doesn't. If you're considering it for any of these uses, talk with your doctor or pharmacist about what the current research actually shows.

The evidence, ingredient by ingredient Cordyceps

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cordyceps is generally well tolerated over the short term, though the safety evidence is limited and product quality varies widely. The most common side effects are mild and affect the digestive system: abdominal discomfort, constipation, and diarrhea.

These are uncommon, and some people found symptoms eased by taking cordyceps with food. There's one case report of liver inflammation (hepatitis) in someone using a cordyceps product, but it's unclear whether cordyceps itself was to blame or if an unknown contaminant caused it.

There isn't enough safety data during pregnancy or breastfeeding, so the data advises against use in both. Because product quality varies widely in this category, buying from a reputable supplier matters.

Side effects, ingredient by ingredient Cordyceps

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cordyceps.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 249 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take blood thinners (anticoagulants) or antiplatelet drugs — cordyceps may theoretically increase bleeding risk. Also confirm use if you take immunosuppressants (such as after transplant) or testosterone, both moderate or minor concerns.

No interactions are documented for the one ingredient we checked beyond these categories.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Cordyceps may be worth a try if you're interested in traditional energy support, though the evidence for athletic or sexual performance is weak or absent. If you take blood thinners, immunosuppressants, or testosterone, check your exact medications with your doctor or pharmacist first — cordyceps may interact with them.

It's not for pregnancy or breastfeeding. Start a conversation with your own healthcare provider about whether it makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cordyceps 10:1 Mushroom Extract, straight from the product label.

Brand Nootropics Depot
Net contents 60 Gram(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 231927
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cordyceps 10:1 Mushroom Extract by Nootropics Depot, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Gram(s)
Maximum serving Sizes:
0.25 Gram(s)
Servings per container
240
IngredientAmount% DV
Cordyceps militaris 10:1 extract260 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formula

Beta-Glucan minimum content: 20% Cordycepin minimum content: 0.3%

Precautions

Disclaimer: Always consult with a qualified health physician before taking any new dietary supplement.

Warning: Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and are taking prescription drug(s) or OTD medication(s).

Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and are taking prescription drug(s) or OTD medication(s).

FDA Disclaimer Statement

This product is not intended to diagnose, treat, cure or prevent any diseases. Theses statements have not been evaluated by the Food and Drug Administration.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 250mg 1-2 times daily.

General Statements

Transfer scoops are not accurate source of measurement. A milligram scale is needed to accurately measure dosages.

Storage

Storage: Store in a cool and dry place. Keep away from direct sunlight and heat.

Formulation

Non GMO

USDA Organic

Seals/Symbols

USDA Organic

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cordyceps 10:1 Mushroom Extract by Nootropics Depot label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cordyceps 10:1 Mushroom Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cordyceps 10:1 Mushroom Extract by Nootropics Depot

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Gram(s) Dosage formPowder Servings per container240 Amounts shown are per serving.

Cordyceps militaris 10:1 extract

Interacts with
249 drugs
260 mg per serving

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Cordyceps militaris 10:1 extract monograph & interactions
Interaction report

Cordyceps 10:1 Mushroom Extract by Nootropics Depot Drug Interactions

Want to check YOUR meds against Cordyceps 10:1 Mushroom Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
249Drugs
241 Moderate 8 Minor

Ingredients driving the most interactions

Cordyceps militaris 10:1 extract 249

Individual Drug Interactions

The ingredients in Cordyceps 10:1 Mushroom Extract interact with 249 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cordyceps 10:1 Mushroom Extract interact with drugs. Each result below shows which ingredient is responsible. Cordyceps militaris 10:1 extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Cordyceps 10:1 Mushroom Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cordyceps militaris 10:1 extract3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
Cordyceps militaris 10:1 extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cordyceps 10:1 Mushroom Extract, from the product label.

Nootropics Depot

See all Nootropics Depot products
Name
Nootropics Depot
Street Address
8380 S. Kyrene Rd. Ste. 110
City
Tempe
State
AZ
ZipCode
85284
Web Address
nootropicsdepot.com
Pharmacist Counseling Corner

Cordyceps 10:1 Mushroom Extract by Nootropics Depot: Common Questions

Does Cordyceps 10:1 Mushroom Extract by Nootropics Depot interact with any medications?
Yes. Based on its ingredients, Cordyceps 10:1 Mushroom Extract has a known interaction with 249 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cordyceps 10:1 Mushroom Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does cordyceps actually boost athletic performance?
The available data rates it as possibly ineffective for athletic performance. While cordyceps is popular in sports circles, reliable research doesn't back up the claim that it enhances exercise capacity. You might still try it, but manage your expectations based on what the evidence shows.
Is this safe to take every day, long-term?
Cordyceps has been used for up to a year in studies and is generally well tolerated, but the long-term safety evidence is limited. Product quality varies widely, so where you buy matters. Talk to your pharmacist if you plan to take it regularly.
What side effects might I notice?
Most people don't experience side effects. When they do occur, they're mild and digestive: abdominal discomfort, diarrhea, or constipation. Dry mouth and throat discomfort have also been reported rarely. Taking it with food may help reduce stomach upset.
Can I take this if I'm pregnant or breastfeeding?
No — there isn't enough safety data during pregnancy or breastfeeding, so the safety data advises against use in both. Talk with your doctor about other options if you're pregnant or nursing.
What is cordyceps, exactly?
Cordyceps is a fungus used for centuries in traditional medicine. This product is a concentrated extract — 10 parts raw mushroom material condensed down to 1 part extract — which makes it more potent than raw powder.
I take blood thinners. Can I use this?
Not without checking first. Cordyceps may theoretically increase bleeding risk when combined with blood thinners or antiplatelet drugs, though this hasn't been documented in people yet. Check with your doctor or pharmacist about your specific medication before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cordyceps 10:1 Mushroom Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cordyceps 10:1 Mushroom Extract label
Go deeper

The Full Monographs Behind Cordyceps 10:1 Mushroom Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cordyceps

Interacts with 249 drugs

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...

Read the full Cordyceps monograph →
Sources

Sources & How We Checked

Cordyceps 10:1 Mushroom Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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