Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Cordyceps 4X Ingredients & Drug Interactions

by Pure Essence MyPure

Cordyceps 4X label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cordyceps 4X against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cordyceps 4X is a dietary supplement by Pure Essence MyPure with 2 active ingredients. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Organic Cordyceps militaris mushroom extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cordyceps 4X by Pure Essence MyPure

Ask about any prescription or over-the-counter medication and we check it for interactions with Cordyceps 4X by Pure Essence MyPure — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cordyceps 4X by Pure Essence MyPure

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Cordyceps 4X contains 2 active ingredients, both the same: organic Cordyceps militaris mushroom extract. This is a fungal extract — cordyceps is a type of medicinal mushroom traditionally used to support energy and endurance.

The product also includes HPMC, a capsule material.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: supports healthy stress response and maximum performance.
  • We looked for evidence on: Athletic performance, Fatigue, stamina, energy, endurance.
  • The closest evidence on file: Cordyceps is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Cordyceps is rated "Insufficient Reliable Evidence To Rate" for Fatigue.

The evidence for cordyceps is patchy. For athletic performance, the data suggests it's probably ineffective.

For sexual dysfunction, irregular heartbeat (arrhythmia), asthma, lung cancer, and chronic obstructive pulmonary disease (COPD), there simply isn't enough reliable evidence to say one way or the other. If you're considering this for one of those uses, talk with your doctor about whether the evidence makes sense for your situation.

The evidence, ingredient by ingredient Cordyceps

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cordyceps is generally well tolerated when used short-term — most people don't have problems. That said, the evidence overall is limited, and mushroom product quality varies a lot from brand to brand.

The most common side effects in trials were uncommon and mild: belly discomfort, constipation, diarrhea, dry mouth, and throat discomfort. Taking it with food may help reduce these.

There's one case report of liver inflammation (hepatitis) possibly tied to cordyceps, though it's unclear whether the cordyceps itself or a contaminant was responsible. During pregnancy, there isn't enough safety data, so it's best avoided.

The same goes for breastfeeding — the data just isn't there to know if it's safe for your baby.

Side effects, ingredient by ingredient Cordyceps

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cordyceps.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 249 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Cordyceps 4X, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs — cordyceps may increase bleeding risk. Also confirm it's safe if you use immunosuppressants like cyclosporine, or if you're on testosterone therapy.

These are the main medication interactions to verify.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Cordyceps 4X is generally well tolerated short-term, but the evidence for its most common claimed uses is weak or absent. If you take blood thinners, immunosuppressants, or testosterone therapy, you need to check with your own doctor or pharmacist before starting this — the interactions are theoretical but not trivial.

Avoid it during pregnancy or breastfeeding. Your healthcare provider can help you weigh whether this supplement makes sense for what you're hoping to treat.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cordyceps 4X, straight from the product label.

Brand Pure Essence MyPure
Barcode (UPC) 659670921018
Net contents 30 Vegi-Cap(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 230984
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cordyceps 4X by Pure Essence MyPure, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
659670921018
IngredientAmount% DV
Organic Cordyceps militaris mushroom extract300 mg--
organic Cordyceps militaris mushroom extract200 mg--

Other ingredients: HPMC

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Non GMO

Vegan

Gluten Free

Organic ingredients

100% purity & potency guarantee

Supports healthy stress response & maximum performance

Over 4 times stronger

Does not contain: Wheat, milk, tree nuts, peanuts, soy, eggs, fish, shellfish

General Statements

90 day Money back guarantee

1 month supply

Please recycle

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Copyright 2018 All rights reserved

Formula

MyPure Cordyceps 4X combines 1:1 and 10:1 extracts of certified organic cordyceps fruiting bodies to deliver the most potent cordyceps nutrition you'll find. Every batch is lab tested for cleanliness, purity and potency. Cordyceps supports: Maximum physical & mental perfomance Healthy stress response Healthy immune function Healthy lung & kidney systems

100% certified organic whole mushroom fruiting body extract. This product provides at least 20% Beta-(1,3)91,6) D-Glucans

Suggested/Recommended/Usage/Directions

Suggested Use: One capsule daily.

Storage

Storage: Keep closed in a cool, dry place.

Precautions

Caution: Keep all supplements out of children's reach.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Made in USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cordyceps 4X by Pure Essence MyPure label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cordyceps 4X label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cordyceps 4X by Pure Essence MyPure

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic Cordyceps militaris mushroom extract

Interacts with
249 drugs
300 mg per serving

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Organic Cordyceps militaris mushroom extract monograph & interactions

Organic Cordyceps militaris mushroom extract

Interacts with
249 drugs
200 mg per serving

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Organic Cordyceps militaris mushroom extract monograph & interactions

Other (inactive) ingredients: HPMC. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cordyceps 4X by Pure Essence MyPure Drug Interactions

Want to check YOUR meds against Cordyceps 4X?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
249Drugs
241 Moderate 8 Minor

Ingredients driving the most interactions

Organic Cordyceps militaris mushroom extract 249

Individual Drug Interactions

The ingredients in Cordyceps 4X interact with 249 drugs. Click any drug to see the details.

1 of the 2 ingredients in Cordyceps 4X interact with drugs. Each result below shows which ingredient is responsible. Organic Cordyceps militaris mushroom extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Cordyceps 4X with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Organic Cordyceps militaris mushroom extract3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
Organic Cordyceps militaris mushroom extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cordyceps 4X, from the product label.

Pure Essence MyPure

See all Pure Essence MyPure products
Name
Pure Essence Laboratories, Inc.
Street Address
P.O. Box 95397
City
Las Vegas
State
NV
ZipCode
89193
Web Address
www.pureessencelabs.com
Pharmacist Counseling Corner

Cordyceps 4X by Pure Essence MyPure: Common Questions

Does Cordyceps 4X by Pure Essence MyPure interact with any medications?
Yes. Based on its ingredients, Cordyceps 4X has a known interaction with 249 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cordyceps 4X contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is cordyceps safe if I'm trying to get pregnant or am already pregnant?
There isn't enough safety data to know, so it's best avoided during pregnancy. If you're planning pregnancy or are already pregnant, talk with your doctor about whether you should take this.
Can I take this while breastfeeding?
Not enough safety data exists for breastfeeding either, so it's best avoided. Discuss this with your doctor or pharmacist if you're nursing and want to use cordyceps.
What side effects might I have?
Most people tolerate it well. The uncommon side effects from trials were belly discomfort, constipation, diarrhea, dry mouth, and throat discomfort — and sometimes these lessened if you took it with food.
Does cordyceps actually improve athletic performance?
The evidence suggests it's probably ineffective for that. For other uses like sexual dysfunction or asthma, there simply isn't enough reliable evidence to say whether it works.
How long can I safely use cordyceps?
The data shows it's generally well tolerated for up to a year. Beyond that, evidence is limited, so check with your pharmacist or doctor if you're planning longer use.
What's in this product besides the active ingredient?
The only other ingredient is HPMC, which is a standard capsule material.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cordyceps 4X is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cordyceps 4X label
Go deeper

The Full Monographs Behind Cordyceps 4X’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cordyceps

Interacts with 249 drugs

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...

Read the full Cordyceps monograph →
Sources

Sources & How We Checked

Cordyceps 4X's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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