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Dietary supplement

Cordyceps-Pure Ingredients & Drug Interactions

by Confidence USA

Cordyceps-Pure label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cordyceps-Pure against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cordyceps-Pure is a dietary supplement by Confidence USA with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cordyceps (Cordyceps sinensis) mycelium extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cordyceps-Pure by Confidence USA

Ask about any prescription or over-the-counter medication and we check it for interactions with Cordyceps-Pure by Confidence USA — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cordyceps-Pure by Confidence USA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Cordyceps-Pure contains one active ingredient: cordyceps mycelium extract (Cordyceps sinensis). This is a fungal extract used traditionally to support energy and endurance.

The capsule also includes inactive ingredients—microcrystalline cellulose, magnesium stearate, and the capsule shell itself—which are standard binders and fillers.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: immune boost and overall health.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for cordyceps is mixed and limited. For athletic performance, it's rated possibly ineffective.

For sexual dysfunction, asthma, lung cancer, COPD, and irregular heartbeat (arrhythmia), we don't have enough reliable evidence to say whether it works or not. If you're considering cordyceps for any of these uses, talk it over with your doctor about what the current research actually supports.

The evidence, ingredient by ingredient Cordyceps

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cordyceps is generally well tolerated when used short-term, though the evidence base is limited and product quality varies widely. The most common side effects reported in studies were mild—abdominal discomfort, diarrhea, and constipation—and some people found these improved by taking it after eating.

There's one case report of liver inflammation (cholestasis) in a person taking a cordyceps product, though it's unclear whether cordyceps or a contaminant caused it. Not enough safety data exists to recommend cordyceps during pregnancy or while breastfeeding.

If you're pregnant, nursing, or planning either, talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Cordyceps

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cordyceps.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 249 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before starting if you take blood thinners or antiplatelet drugs (like warfarin, clopidogrel, or aspirin)—cordyceps may increase bleeding risk. Also confirm if you take immunosuppressants like cyclosporine, or if you're on testosterone therapy.

If you take any of these, they should review this product with you first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Cordyceps-Pure might appeal to people looking for natural energy support, but the evidence for most uses is thin or absent. The main caution is interaction risk with blood thinners, immune-suppressing drugs, and testosterone—so check your medications first.

Because product quality varies and safety data in pregnancy and breastfeeding is limited, confirm with your own doctor or pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cordyceps-Pure, straight from the product label.

Brand Confidence USA
Barcode (UPC) 892483001748
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 246549
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cordyceps-Pure by Confidence USA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
892483001748
IngredientAmount% DV
Cordyceps (Cordyceps sinensis) mycelium extract1000 mg--

Other ingredients: Capsule Shell, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: If you are pregnant, nursing, have been diagnosed with an auto-immune disorder, or taking any medications, consult your physician before using this product.

Discontinue use and contact your physician if any adverse reactions occur.

Keep out of reach of children.

If outer safety seal is broken or missing, do not consume.

Formula

Cordyceps-Pure is scientifically formulated with 100% natural pure Cordyceps Mycelium Extract containing natural beneficial compounds including organic acids, polysaccharides, amino acids, sterols, vitamins, minerals and more.

Formulation

Cordyceps has become one of the most effective herbs in aiding immune boost and overall health.

Cordyceps-Pure is manufactured by Confidence USA, Inc., an FDA registered manufacturer following strict current Good Manufacturing Practices. (FDA Registration# 10362791850 - Product Code# FP0261)

Made in USA

100% Pure potency guaranteed Supports overall health and immune function

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practice

General Statements

For more info and reorders: www.ConfidenceUSA.com Better products for a better life

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adult - Take 2 capsules daily as dietary supplement.

Storage

Store at room temperature, with lid tightly closed.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cordyceps-Pure by Confidence USA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cordyceps-Pure label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cordyceps-Pure by Confidence USA

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Cordyceps (Cordyceps sinensis) mycelium extract

Interacts with
249 drugs
1000 mg per serving

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Cordyceps (Cordyceps sinensis) mycelium extract monograph & interactions

Other (inactive) ingredients: Capsule Shell, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cordyceps-Pure by Confidence USA Drug Interactions

Want to check YOUR meds against Cordyceps-Pure?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
249Drugs
241 Moderate 8 Minor

Ingredients driving the most interactions

Cordyceps (Cordyceps sinensis) mycelium extract 249

Individual Drug Interactions

The ingredients in Cordyceps-Pure interact with 249 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cordyceps-Pure interact with drugs. Each result below shows which ingredient is responsible. Cordyceps (Cordyceps sinensis) mycelium extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Cordyceps-Pure with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cordyceps (Cordyceps sinensis) mycelium extract3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
Cordyceps (Cordyceps sinensis) mycelium extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cordyceps-Pure, from the product label.

Confidence USA

See all Confidence USA products
Name
Confidence USA, Inc.
City
Port Washington
State
NY
ZipCode
11050
Phone Number
1-800-887-7161
Web Address
www.Confidence USA.com
Pharmacist Counseling Corner

Cordyceps-Pure by Confidence USA: Common Questions

Does Cordyceps-Pure by Confidence USA interact with any medications?
Yes. Based on its ingredients, Cordyceps-Pure has a known interaction with 249 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cordyceps-Pure contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Cordyceps-Pure if I'm pregnant or breastfeeding?
There isn't enough safety data on cordyceps during pregnancy or breastfeeding. The safety information advises against use in both. Talk with your doctor or pharmacist about your individual situation to decide what's best for you.
What side effects might I experience?
Most people tolerate cordyceps well. The most common side effects in studies were mild—abdominal discomfort, diarrhea, and constipation. Taking it with food may help reduce these. Dry mouth and throat discomfort have also been reported but are uncommon.
Will cordyceps actually boost my athletic performance?
The evidence suggests cordyceps is possibly ineffective for athletic performance. If you're looking for ergogenic support, talk with your doctor about options with stronger evidence behind them.
What is cordyceps extract, and where does it come from?
Cordyceps is a fungal extract from Cordyceps sinensis. This product uses mycelium extract—the vegetative part of the fungus—which is used traditionally to support energy. Quality varies widely among products on the market.
How long can I safely take cordyceps?
Cordyceps appears to be well tolerated when used for up to 1 year. Beyond that timeframe, safety data is limited. If you plan to use it longer term, discuss it with your doctor or pharmacist.
Does this product have any fillers?
Yes. In addition to the cordyceps extract, the capsule contains microcrystalline cellulose (a binder), magnesium stearate (a flow agent), and the capsule shell itself. These are standard inactive ingredients in most supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cordyceps-Pure label
Go deeper

The Full Monographs Behind Cordyceps-Pure’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cordyceps

Interacts with 249 drugs

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...

Read the full Cordyceps monograph →
Sources

Sources & How We Checked

Cordyceps-Pure's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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