Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Glucosamine Super Ingredients & Drug Interactions

by Confidence USA

Glucosamine Super label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glucosamine Super against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Glucosamine Super is a dietary supplement by Confidence USA with 2 active ingredients. Its ingredients are commonly taken for osteoarthritis, joint pain and stiffness, cartilage support.Based on those ingredients, 1,135 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Glucosamine Super Proprietary Joint Support Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Glucosamine Super by Confidence USA

Ask about any prescription or over-the-counter medication and we check it for interactions with Glucosamine Super by Confidence USA — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Glucosamine Super by Confidence USA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 7 active ingredients.
  • “Glucosamine Super Proprietary Joint Support Blend” is a proprietary blend — the label gives one combined amount (1,200 mg) without saying how much of each component you get.
  • “Glucosamine Super Proprietary Joint Comfort Blend” is a proprietary blend — the label gives one combined amount (900 mg) without saying how much of each component you get.

Glucosamine Super contains 7 active ingredients. Glucosamine hydrochloride and chondroitin sulfate are the main ones — both are naturally occurring compounds in cartilage that you're taking as supplements to support your joints.

Turmeric root extract brings curcumin, the compound thought to reduce inflammation. Hyaluronic acid is a humectant (a moisture binder) found in connective tissue.

Frankincense resin extract is an herbal anti-inflammatory. The product also includes methylsulfonylmethane and white willow bark extract, which support joint health through different mechanisms.

The rest of the tablet is made up of inactive ingredients — microcrystalline cellulose, dicalcium phosphate, stearic acid, magnesium stearate, croscarmellose sodium, silicon dioxide, hypromellose, titanium dioxide, propylene glycol, triacetin, and purified water — these are the binders, fillers, and coating that hold the tablet together and help it dissolve.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support joint function, flexibility and comfort.
  • We looked for evidence on: Joint pain, Knee pain, Back pain, Osteoarthritis, Joint stiffness, Range of motion.
  • The strongest evidence on file: Glucosamine is rated "Likely Effective" for Osteoarthritis (Natural Medicines).
  • Also on file: Turmeric is rated "Possibly Effective" for Osteoarthritis.
  • Also on file: Chondroitin Sulfate is rated "Possibly Effective" for Osteoarthritis.

Glucosamine hydrochloride is rated likely effective for osteoarthritis, the most common reason people take it. Chondroitin sulfate and hyaluronic acid are both rated possibly effective for osteoarthritis and possibly effective for cataracts and dry eye respectively.

Turmeric root extract is possibly effective for depression, high cholesterol, hay fever, and indigestion. Frankincense resin extract, methylsulfonylmethane, and white willow bark extract don't have established effectiveness ratings in our data for the conditions this product targets.

For aging skin and back pain, the evidence we hold is insufficient to rate any of these ingredients.

The evidence, ingredient by ingredient Glucosamine Hyaluronic Acid Chondroitin Sulfate Turmeric Frankincense

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The ingredients in this product are generally well tolerated by most adults when taken by mouth. The most common side effects from glucosamine and chondroitin are mild digestive issues — bloating, constipation, diarrhea, nausea, and heartburn.

Turmeric may cause similar GI effects plus headache or dizziness, and there are rare reports of liver damage with turmeric supplements taken for weeks or longer. Hyaluronic acid taken orally has limited long-term safety data.

Frankincense is generally well tolerated topically and by inhalation, though allergic skin reactions have been reported rarely. Some people are sensitive to glucosamine products — a small number experience allergic reactions ranging from mild (itching, hives) to severe (breathing difficulty, low blood pressure), and in very rare cases anaphylaxis has occurred.

Asthma exacerbations have also been reported with glucosamine-chondroitin combinations. Pregnancy and breastfeeding safety data are not sufficient for hyaluronic acid, glucosamine hydrochloride, chondroitin sulfate, and frankincense — the safety facts advise against use unless your doctor advises otherwise.

No pregnancy or lactation data are on file for turmeric root extract or methylsulfonylmethane. Talk with your pharmacist or doctor about whether this product is right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Glucosamine Hyaluronic Acid Chondroitin Sulfate Turmeric Frankincense

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 5 matched ingredients can interact with medications — Turmeric, Chondroitin Sulfate, Glucosamine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; cancer treatments; diabetes medications.
  • For scale: 1,136 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting Glucosamine Super, double-check with your pharmacist if you take warfarin (a blood thinner) — both glucosamine and chondroitin may increase its blood-thinning effect and your bleeding risk. Turmeric may reduce the effectiveness of chemotherapy drugs like doxorubicin or topoisomerase inhibitors, increase blood levels of tacrolimus, tamoxifen, or sulfasalazine, and theoretically affect tramadol and methotrexate.

Glucosamine may have minor interactions with antidiabetes drugs and acetaminophen. No interactions are documented in our data for methylsulfonylmethane and white willow bark extract.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Glucosamine Super is primarily for osteoarthritis support — glucosamine itself is likely effective for that. If you take warfarin or any chemotherapy, immunosuppressant, or inflammatory-bowel-disease medication, you need to check this product with your pharmacist first.

Digestive upset is common. Pregnancy and breastfeeding safety aren't well established for most ingredients, so discuss it with your doctor or pharmacist if either applies to you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glucosamine Super, straight from the product label.

Brand Confidence USA
Barcode (UPC) 810891028386
Net contents 120 Easy Swallow Tablet(s)
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 319350
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glucosamine Super by Confidence USA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Tablet(s)
Maximum serving Sizes:
4 Tablet(s)
Servings per container
30
UPC/BARCODE
810891028386
IngredientAmount% DV
Methylsulfonylmethane0 NP--
Hyaluronic Acid0 NP--
Glucosamine Hydrochloride0 NP--
Chondroitin Sulfate0 NP--
Turmeric Root Extract0 NP--
Frankincense Resin Extract0 NP--
Glucosamine Super Proprietary Joint Support Blend1200 mg--
Glucosamine Super Proprietary Joint Comfort Blend900 mg--
White Willow Bark Extract0 NP--

Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Stearic Acid, Magnesium Stearate, Croscarmellose Sodium, Silicon Dioxide, Hypromellose, Titanium Dioxide, Propylene Glycol, Triacetin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: If you are pregnant, lactating or on prescribed medication, consult your physician before using.

Keep out of reach of children.

If outer safety seal is broken or missing, do not consume.

Allergen: Contains shellfish (shrimp, crab and crayfish).

Formula

Glucosamine Super is a powerful combination of Glucosamine, Chondroitin, Hyaluronic Acid, MSM and natural complex to support joint function and comfort. Glucosamine and Chondroitin help support joint flexibility, range of motion and cushioning of your joints. MSM is important in the formation of collagen, and Hyaluronic Acid supports joint lubrication. White Willow Bark and Turmeric Extract's potential to support joint comfort are well recognized.

Glucosamine Super with white willow bark & curcumin

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Glucosamine Super is manufactured by Confidence USA, Inc., an FDA registered manufacturer following strict Good Manufacturing Practices. (FDA Registration# 10362791850 - Product Code# FP0394) Made in USA

Fast acting 5 Benefits for joint health Lubrication Flexibility Strength Comfort Mobility

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adult - Take 4 tablets daily with food as dietary supplement.

Storage

Store at room temperature, with lid tightly closed.

Seals/Symbols

GMP Good Manufacturing Practice

General Statements

Customer info: Confidence USA, Inc. Port Washington, NY 11050 USA/Canada: 1-800-887-7161 Other Countries: 001-516-767-1860 For more info and reorders: www.ConfidenceUSA.com Better products for a better life

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glucosamine Super by Confidence USA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glucosamine Super label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glucosamine Super by Confidence USA

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Glucosamine Super Proprietary Joint Support Blend

Interacts with
170 drugs
1200 mg per serving

Glucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of...

Glucosamine Super Proprietary Joint Support Blend monograph & interactions

Glucosamine Super Proprietary Joint Comfort Blend

Interacts with
170 drugs
900 mg per serving

Glucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of...

Glucosamine Super Proprietary Joint Comfort Blend monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Stearic Acid, Magnesium Stearate, Croscarmellose Sodium, Silicon Dioxide, Hypromellose, Titanium Dioxide, Propylene Glycol, Triacetin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glucosamine Super by Confidence USA Drug Interactions

Want to check YOUR meds against Glucosamine Super?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,135Drugs
2 Major 1,055 Moderate 78 Minor

Ingredients driving the most interactions

Glucosamine Super Proprietary Joint Support Blend 170

Individual Drug Interactions

The ingredients in Glucosamine Super interact with 1,135 drugs. Click any drug to see the details.

1 of the 2 ingredients in Glucosamine Super interact with drugs. Each result below shows which ingredient is responsible. Glucosamine Super Proprietary Joint Support Blend

Each ingredient & the kinds of drugs it affects

For each ingredient in Glucosamine Super with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glucosamine Super Proprietary Joint Support Blend4 drug types · 170 drugs

Warfarin (Coumadin)

Glucosamine might increase the anticoagulant effects of warfarin and increase the risk of bruising and bleeding.
In two individual case reports, glucosamine/chondroitin combinations were associated with a significant increase in international normalized ratio (INR) in patients previously stabilized on warfarin. In one case, the increase in INR occurred only after tripling the dose of a glucosamine/chondroitin supplement from 500 mg/400 mg daily to 1500/1200 mg daily. Additionally, 20 voluntary case reports to the U.S. Food & Drug Administration (FDA) have linked glucosamine plus chondroitin with increased INR, bruising, and bleeding in patients who were also taking warfarin. There have also been 20 additional case reports to the World Health Organization (WHO) that link glucosamine alone to increased INR in patients taking warfarin. The mechanism of this interaction is unclear. Glucosamine is a small component of heparin, but is not thought to have anticoagulant activity; however, animal research suggests that it might have antiplatelet activity.

Likelihood Probable Evidence D
Topoisomerase Ii Inhibitors

Theoretically glucosamine may induce resistance to topoisomerase II inhibitors.
In vitro research suggests that glucosamine might induce resistance to etoposide (VP16, VePesid) and doxorubicin (Adriamycin) by reducing inhibition of topoisomerase II, an enzyme required for DNA replication in tumor cells. This effect has not been reported in humans.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Anecdotal reports suggest that adding glucosamine to an acetaminophen regimen might decrease pain control in patients with osteoarthritis. Some research suggests that the sulfate portion of glucosamine sulfate might contribute to its effect in osteoarthritis. Since acetaminophen metabolism requires sulfur and reduces serum sulfate concentrations, acetaminophen could theoretically interfere with the action of glucosamine sulfate. Conversely, the administration of sulfate could theoretically decrease the effectiveness of acetaminophen in sulfate-deficient people by increasing its clearance.

Likelihood Possible Evidence B
Antidiabetes Drugs

Despite initial concerns, it is unlikely that glucosamine will interfere with the effects of antidiabetes drugs.
In vitro and animal research has suggested that glucosamine might increase insulin resistance or decrease insulin production. This has raised concerns that taking glucosamine might worsen diabetes and decrease the effectiveness of diabetes drugs. However, clinical research suggests that glucosamine does not have adverse effects on blood glucose or glycated hemoglobin (HbA1C) in healthy, obese, or type 2 diabetes patients.

Likelihood Unlikely Evidence B
Glucosamine Super Proprietary Joint Support Blend full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glucosamine Super, from the product label.

Confidence USA

See all Confidence USA products
Name
Confidence USA, Inc.
City
Port Washington
State
NY
ZipCode
11050
Phone Number
1-800-887-7161
Web Address
www.ConfidenceUSA.com
Pharmacist Counseling Corner

Glucosamine Super by Confidence USA: Common Questions

Does Glucosamine Super by Confidence USA interact with any medications?
Yes. Based on its ingredients, Glucosamine Super has a known interaction with 1,135 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glucosamine Super contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this have glucosamine sulfate or glucosamine hydrochloride?
This product contains glucosamine hydrochloride, not the sulfate form. Both forms are used for joint health, but they're different — the hydrochloride form doesn't carry the same concern about interaction with acetaminophen that glucosamine sulfate does.
Can I take this if I have diabetes?
Glucosamine hydrochloride carries a Minor interaction with antidiabetes drugs, though the practical risk is considered low. If you take insulin or other diabetes medication, mention this product to your pharmacist or doctor — they may want to monitor your blood sugar more closely.
Is this product safe to take long-term?
Glucosamine and chondroitin are generally well tolerated long-term, but turmeric has rare reports of liver damage when taken as a supplement for weeks or months. Long-term safety of hyaluronic acid as a supplement isn't fully studied. If you plan to take this regularly, let your pharmacist know so they can monitor you.
What's the turmeric in here for?
Turmeric root extract (which contains curcumin) is included for its anti-inflammatory properties to support joint and overall comfort. It's rated possibly effective for inflammation-related conditions like indigestion, hay fever, and depression.
Can I take this with ibuprofen or other pain relievers?
Glucosamine may slightly interfere with acetaminophen's pain relief. The product facts don't address interactions with ibuprofen or other NSAIDs. Ask your pharmacist to be sure, especially if you take pain relievers regularly.
Does this product contain any fillers?
Yes — the tablet contains several inactive ingredients like microcrystalline cellulose, magnesium stearate, and silicon dioxide, which are binders and fillers that hold the tablet together and help it dissolve.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glucosamine Super is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glucosamine Super label
Go deeper

The Full Monographs Behind Glucosamine Super’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glucosamine

Interacts with 170 drugs

Glucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of the knee. The evidence is mixed, with so...

Read the full Glucosamine monograph → Herb & supplement monograph

Hyaluronic Acid

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin moisture and joint comfort, and the evi...

Read the full Hyaluronic Acid monograph → Herb & supplement monograph

Chondroitin Sulfate

Interacts with 2 drugs

Chondroitin sulfate is a naturally occurring building block of cartilage that is widely taken, often with glucosamine, for osteoarthritis joint pain. The evidence is mixed—some people report...

Read the full Chondroitin Sulfate monograph → Herb & supplement monograph

Turmeric

Interacts with 1,133 drugs

Turmeric is a popular spice whose main active compounds, curcuminoids, are studied mostly for inflammation and joint pain. Some research is promising, but quality is mixed and curcumin is po...

Read the full Turmeric monograph → Herb & supplement monograph

Frankincense

Frankincense is the aromatic resin of the Boswellia tree and is best known for its boswellic acids, which may help with inflammation and joint pain. Early research is promising for condition...

Read the full Frankincense monograph →
Sources

Sources & How We Checked

Glucosamine Super's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 188 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Glucosamine 58 references
  1. Adams ME. Hype about glucosamine. Lancet 1999;354:353-4. PubMed
  2. Balkan B, Dunning BE. Glucosamine inhibits glucokinase in vitro and produces a glucose-specific impairment of in vivo insulin secretion in rats. Diabetes 1994;43:1173-9. PubMed
  3. Giaccari A, Morviducci L, Zorretta D, et al. In vivo effects of glucosamine on insulin secretion and insulin sensitivity in the rat: possible relevance to the maladaptive responses to chronic hyperglycaemia. Diabetologia 1995;38:518-24. PubMed
  4. Holmang A, Nilsson C, Niklasson M, et al. Induction of insulin resistance by glucosamine reduces blood flow but not interstitial levels of either glucose or insulin. Diabetes 1999;48:106-11. PubMed
  5. Houpt JB, McMillan R, Wein C, Paget-Dellio SD. Effect of glucosamine hydrochloride in the treatment of pain of osteoarthritis of the knee. J Rheumatol 1999;26:2423-30.
  6. Barclay TS, Tsourounis C, McCart GM. Glucosamine. Ann Pharmacother 1998;32:574-9.
  7. Shankar RR, Zhu JS, Baron AD. Glucosamine infusion in rats mimics the beta-cell dysfunction of non-insulin-dependent diabetes mellitus. Metabolism 1998;47:573-7.
  8. Almada A, Harvey P, Platt K. Effects of chronic oral glucosamine sulfate on fasting insulin resistance index (FIRI) in non-diabetic individuals. FASEB J 2000;14:A750.
  9. Reginster JY, Deroisy R, Rovati LC, et al. Long-term effects of glucosamine sulfate on osteoarthritis progression: a randomised, placebo-controlled trial. Lancet 2001;357:251-6.
  10. Does glucosamine increase serum lipid levels and blood pressure? Pharmacist's Letter/Prescriber's Letter 2001;17(11):171115.
  11. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  12. Monauni T, Zenti MG, Cretti A, et al. Effects of glucosamine infusion on insulin secretion and insulin action in humans. Diabetes 2000;49:926-35. PubMed
  13. Pouwels MJ, Jacobs JR, Span PN, et al. Short-term glucosamine infusion does not affect insulin sensitivity in humans. J Clin Endocrinol Metab 2001;86:2099-103. DOI
  14. Yun J, Tomida A, Nagata K, Tsuruo T. Glucose-regulated stresses confer resistance to VP-16 in human cancer cells through a decreased expression of DNA topoisomerase II. Oncol Res 1995;7:583-90.
  15. Pavelka K, Gatterova J, Olejarova M, et al. Glucosamine sulfate use and delay of progression of knee osteoarthritis: A 3-year, randomized, placebo-controlled, double-blind study. Arch Intern Med 2002;162:2113-23. PubMed
  16. Tallia AF, Cardone DA. Asthma exacerbation associated with glucosamine-chondroitin supplement. J Am Board Fam Pract 2002;15:481-4..
  17. Scroggie DA, Albright A, Harris MD. The effect of glucosamine-chondroitin supplementation on glycosylated hemoglobin levels in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial. Arch Intern Med 2003; PubMed
  18. Hoffer LJ, Kaplan LN, Hamadeh MJ, et al. Sulfate could mediate the therapeutic effect of glucosamine sulfate. Metabolism 2001;50:767-70.. PubMed
  19. Yu JG, Boies SM, Olefsky JM. The effect of oral glucosamine sulfate on insulin sensitivity in human subjects. Diabetes Care 2003;26:1941-2. PubMed
  20. Danao-Camara T. Potential side effects of treatment with glucosamine and chondroitin. Arthritis Rheum 2000;43:2853. PubMed
  21. Guillaume MP, Peretz A. Possible association between glucosamine treatment and renal toxicity: comment on the letter by Danao-Camara. Arthritis Rheum 2001;44:2943-4. PubMed
  22. Rozenfeld V, Crain JL, Callahan AK. Possible augmentation of warfarin effect by glucosamine-chondroitin. Am J Health Syst Pharm 2004;61:306-307. PubMed
  23. Tannis AJ, Barban J, Conquer JA. Effect of glucosamine supplementation on fasting and non-fasting plasma glucose and serum insulin concentrations in healthy individuals. Osteoarthritis Cartilage 2004;12:506-11. PubMed
  24. Bush TM, Rayburn KS, Holloway SW, et al. Adverse interactions between herbal and dietary substances and prescription medications: a clinical survey. Altern Ther Health Med 2007;13:30-5.
  25. Stumpf JL, Lin SW. Effect of glucosamine on glucose control. Ann Pharmacother 2006;40:694-8. PubMed
  26. Pham T, Cornea A, Blick KE, et al. Oral glucosamine in doses used to treat osteoarthritis worsens insulin resistance. Am J Med Sci 2007;333:333-9. PubMed
  27. Muniyappa R, Karne RJ, Hall G, et al. Oral glucosamine for 6 weeks at standard doses does not cause or worsen insulin resistance or endothelial dysfunction in lean or obese subjects. Diabetes 2006;55:3142-50. PubMed
  28. Knudsen J, Sokol GH. Potential glucosamine-warfarin interaction resulting in increased international normalized ratio: Case report and review of the literature and MedWatch database. Pharmacotherapy 2008;28:540-8. PubMed
  29. Yue QY, Strandell J, Myrberg O. Concomitant use of glucosamine potentiates the effect of warfarin. Jan 2006. Drug Safety 29(10):911-1010. DOI
  30. Rozendaal RM, Koes BW, van Osch GJVM, et al. Effect of glucosamine sulfate on hip osteoarthritis: A randomized trial. Ann Intern Med 2008;148:268-77. PubMed
  31. Baron AD, Zhu JS, Zhu JH, et al. Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle. Implications for glucose toxicity. J Clin Invest 1995;96(6):2792-801. PubMed
  32. Nelson BA, Robinson KA, Buse MG. High glucose and glucosamine induce insulin resistance via different mechanisms in 3T3-L1 adipocytes. Diabetes 2000;49(6):981-91. PubMed
  33. Giordano N, Fioravanti A, Papakostas P, et al. The efficacy and tolerability of glucosamine sulfate in the treatment of knee osteoarthritis: a randomized, double-blind, placebo-controlled trial. Curr Ther Res Clin Exp 2009;70(3):185-196. PubMed
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See these in context on the Turmeric monograph →

Frankincense 2 references
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  2. Buonomo M, Hylwa S. Allergic contact dermatitis from Boswellia carterii (frankincense) oil. Contact Dermatitis 2021;85(4):465-467.

See these in context on the Frankincense monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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