Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Prostate-7 Ingredients & Drug Interactions

by Confidence USA

Prostate-7 label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Prostate-7 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Prostate-7 is a dietary supplement by Confidence USA with 6 active ingredients. Its ingredients are commonly taken for anti-aging and low dhea levels, mood and depression, vaginal dryness and sexual health.Based on those ingredients, 1,102 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dehydroepiandrosterone, L-Arginine Hydrochloride, Pine Bark Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Prostate-7 by Confidence USA

Ask about any prescription or over-the-counter medication and we check it for interactions with Prostate-7 by Confidence USA — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Prostate-7 by Confidence USA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Prostate-7 Proprietary Blend” is a proprietary blend — the label gives one combined amount (700 mg) without saying how much of each component you get.

Prostate-7 contains 6 active ingredients. DHEA (dehydroepiandrosterone) is a hormone your body naturally makes; this supplement provides it in concentrated form.

Saw palmetto berry extract comes from the berries of a small palm tree and has been studied for prostate and urinary health. L-arginine is an amino acid that your body uses to make nitric oxide, a compound involved in blood vessel relaxation.

Pumpkin seed extract is derived from pumpkin seeds. Pine bark extract and tomato fruit extract round out the blend.

The product also contains inactive ingredients—rice flour, gelatin, colorants (titanium dioxide and FD&C dyes), magnesium stearate, dicalcium phosphate, and silicon dioxide—which serve as fillers and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support prostate gland function and health.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Prostatitis, Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Erectile dysfunction (ED), Overactive bladder, Non-neurogenic lower urinary tract symptoms (LUTS) — and 3 related terms.
  • The strongest evidence on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH).
  • Also on file: Dhea is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED).

The evidence for this product's ingredients is mixed. DHEA has possibly effective evidence for depression and aging skin, and likely effective evidence for vaginal atrophy, though you're taking it here for prostate health—that specific use isn't rated in our data.

Saw palmetto shows possibly ineffective evidence for benign prostatic hyperplasia (enlarged prostate), the condition many people take it for, though it is possibly effective for one prostate-related surgical procedure (TURP). Pumpkin seed extract is rated possibly effective for benign prostatic hyperplasia.

Tomato fruit extract is rated possibly ineffective for several conditions and shows insufficient evidence for benign prostatic hyperplasia. L-arginine, pine bark extract, and the overall prostate-specific effectiveness of this combination are not rated in the evidence we hold.

The evidence, ingredient by ingredient Dhea Saw Palmetto L-arginine Maritime Pine Pumpkin Tomato

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

DHEA is generally well tolerated short-term in typical doses, but long-term use may carry a higher cancer risk—this is a hormone and needs medical supervision. The most common side effects are acne, headache, insomnia, mood changes, and nausea.

Women may experience masculinization (voice deepening, increased body hair, irregular periods). Men may experience aggression or breast tenderness.

DHEA should not be used in pregnancy (rated possibly unsafe) or while breastfeeding. Saw palmetto is generally well tolerated; mild side effects include abdominal pain, constipation, diarrhea, dizziness, fatigue, headache, nausea, and decreased sex drive.

Rarely, skin reactions or heart rhythm changes have been reported. It's rated likely unsafe in pregnancy and should be avoided while breastfeeding.

L-arginine is generally well tolerated but can lower blood pressure and cause abdominal pain, bloating, nausea, diarrhea, headache, insomnia, or flushing; there's no established safety for self-treatment. Pumpkin seed products are generally well tolerated, though abdominal discomfort, diarrhea, nausea, and vomiting can occur; anaphylaxis is rare.

Tomato fruit extract is well tolerated in typical amounts and is rated likely safe in pregnancy.

Side effects, ingredient by ingredient Dhea Saw Palmetto L-arginine Maritime Pine Pumpkin Tomato

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Dhea, Pumpkin, L-arginine, Saw Palmetto, Maritime Pine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 1,103 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Prostate-7, double-check with your pharmacist if you take antidepressants (especially SSRIs)—DHEA carries a moderate risk of psychiatric effects. Blood thinners (anticoagulants or antiplatelets) are a concern with DHEA and saw palmetto.

Blood pressure medications, ACE inhibitors, and angiotensin receptor blockers may be affected by L-arginine. Potassium-sparing diuretics and ARBs carry a moderate risk of high potassium levels.

Diabetes drugs, estrogens, birth control, and lithium are also listed. Check the full list on this page before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Prostate-7 combines several ingredients with evidence for prostate or urinary health, though the strength of that evidence varies. Because DHEA is a hormone with serious interactions and safety concerns, and because L-arginine interacts with blood pressure and heart medications, this product isn't suitable for everyone—you need to check your medications with your pharmacist first.

Talk with your doctor or pharmacist before starting, especially if you take antidepressants, blood thinners, blood pressure drugs, diabetes medications, mood stabilizers, or hormone therapies.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prostate-7, straight from the product label.

Brand Confidence USA
Barcode (UPC) 892483001113
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 319351
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prostate-7 by Confidence USA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
15
UPC/BARCODE
892483001113
IngredientAmount% DV
Dehydroepiandrosterone0 NP--
Saw Palmetto Berry Extract0 NP--
L-Arginine Hydrochloride0 NP--
Prostate-7 Proprietary Blend700 mg--
Pine Bark Extract0 NP--
Pumpkin Seed Extract0 NP--
Tomato Fruit Extract0 NP--

Other ingredients: Rice Flour, Bovine Gelatin, Titanium Dioxide, FD&C Yellow #5, FD&C Blue #1, FD&C Red #3, Magnesium Stearate, Dicalcium Phosphate Dihydrate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Adult - Take 2 capsules once daily as dietary supplement, preferably in the evening. Do not exceed the recommended serving size.

Storage

Store at room temperature, with lid tightly closed.

Precautions

Do not exceed the recommended serving size. Warning: Do not use this product without consulting your physician if you have enlarged prostate, diabetes, or liver problems. Please discontinue use of this product and consult your physician or pharmacist if you experience agitation, skin problems, or any other adverse reactions.

Keep out of reach of children.

If outer safety seal is broken or missing, do not consume.

Formula

Prostate-7 is a formula to revive a man's youth and support the function of the prostate gland. Prostate-7 utilizes a comprehensive nutritional approach with a combination of Pine Bark Extract, L-Arginine and beneficial herbal extracts to help promote prostate health.

Prostate-7 with pine bark extract

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

A natural formula for anti-aging & prostate health

Supports: Normal urinary/bladder function Prostate health Overall immune system Made in USA

Prostate-7 is manufactured by Confidence USA, Inc., an FDA registered manufacturer following strict current Good Manufacturing Practices. (FDA Registration# 10362791850- Product Code #FP0681)

FDA Statement of Identity

Dietary Supplement

General Statements

Customer info: Confidence USA, Inc. Port Washington, NY 11050 USA/Canada: 1-800-887-7161 Other Countries: 001-516-767-1860 www.ConfidenceUSA.com

Seals/Symbols

GMP Good Manufacturing Practice

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Prostate-7 by Confidence USA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Prostate-7 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Prostate-7 by Confidence USA

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container15 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Rice Flour, Bovine Gelatin, Titanium Dioxide, FD&C Yellow #5, FD&C Blue #1, FD&C Red #3, Magnesium Stearate, Dicalcium Phosphate Dihydrate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prostate-7 by Confidence USA Drug Interactions

Want to check YOUR meds against Prostate-7?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,102Drugs
1,099 Moderate 3 Minor

Ingredients driving the most interactions

Dehydroepiandrosterone 776
L-Arginine Hydrochloride 403
Pine Bark Extract 327
Saw Palmetto Berry Extract 174
Pumpkin Seed Extract 1

Individual Drug Interactions

The ingredients in Prostate-7 interact with 1,102 drugs. Click any drug to see the details.

5 of the 6 ingredients in Prostate-7 interact with drugs. Each result below shows which ingredient is responsible. Dehydroepiandrosterone L-Arginine Hydrochloride Pine Bark Extract Saw Palmetto Berry Extract Pumpkin Seed Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Prostate-7 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dehydroepiandrosterone10 drug types · 776 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Human and laboratory research show that DHEA and DHEA-S can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidepressant Drugs

Theoretically, DHEA might increase the risk of psychiatric adverse events when used with antidepressants.
In a human case report, the use of a selective serotonin reuptake inhibitor (SSRI) with DHEA caused a manic episode. Concern for this interaction may be greater in younger individuals with higher baseline DHEA levels.

Likelihood Possible Evidence D
Aromatase Inhibitors

Theoretically, DHEA might interfere with the clinical effects of aromatase inhibitors.
DHEA is a potent estrogen agonist, which may antagonize the anti-estrogen activity of aromatase inhibitors.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Some preliminary evidence shows that DHEA may inhibit CYP3A4; however, the clinical significance of this potential interaction is not known.

Likelihood Possible Evidence D
Fulvestrant (Faslodex)

Theoretically, DHEA might interfere with the anti-estrogen effects of fulvestrant.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist action of fulvestrant in estrogen-receptor positive cancer cells.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, DHEA might interfere with the anti-estrogen effects of tamoxifen.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist activity of tamoxifen in estrogen-receptor positive cancer cells.

Likelihood Possible Evidence D
Triazolam (Halcion)

DHEA can increase blood levels of triazolam.
Administration of DHEA 200 mg daily for two weeks was shown to inhibit the cytochrome P450 3A4 (CYP3A4) metabolism of triazolam. This inhibition appears to be due to DHEA-S, rather than DHEA.

Likelihood Probable Evidence D
Tuberculosis Vaccine

DHEA might reduce the effectiveness of the tuberculosis vaccine.
Animal research shows that high doses of DHEA can reduce the efficacy of the Bacillus Calmette-Guérin (BCG) tuberculosis vaccine.

Likelihood Possible Evidence D
Estrogens

Theoretically, DHEA might increase the effects and adverse effects of estrogen therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. Also, in clinical research, estrogen-progestin oral contraceptives and conjugated estrogens reduce blood levels of DHEA and DHEA-S. The clinical significance of these findings is unclear.

Likelihood Possible Evidence D
Testosterone

Theoretically, DHEA might increase the effects and side effects of testosterone therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. The clinical significance of these findings is unclear.

Likelihood Possible Evidence D
Dehydroepiandrosterone full monograph & interactions

L-Arginine Hydrochloride9 drug types · 403 drugs

Ace Inhibitors (Aceis)

Theoretically, concomitant use of L-arginine and ACE inhibitors may increase the risk for hypotension and hyperkalemia.
Combining L-arginine with some antihypertensive drugs, especially ACE inhibitors, seems to have additive vasodilating and blood pressure-lowering effects. Furthermore, ACE inhibitors can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ACE inhibitors with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, concomitant use of L-arginine and ARBs may increase the risk of hypotension and hyperkalemia.
L-arginine increases nitric oxide, which causes vasodilation. Combining L-arginine with ARBs seems to increase L-arginine-induced vasodilation. Furthermore, ARBs can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ARBs with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of L-arginine with anticoagulant and antiplatelet drugs might have additive effects and increase the risk of bleeding.
Preliminary research suggests that L-arginine infusions reduce platelet aggregation in humans. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of L-arginine might have additive effects with antidiabetes drugs.
Preliminary clinical research shows that L-arginine decreases blood glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.
L-arginine increases nitric oxide, which causes vasodilation. Clinical evidence shows that L-arginine can reduce blood pressure in some individuals with hypertension. Furthermore, combining L-arginine with some antihypertensive drugs seems to have additive vasodilating and blood pressure-lowering effects.

Likelihood Probable Evidence D
Isoproterenol (Isuprel)

Theoretically, concurrent use of isoproterenol and L-arginine might result in additive effects and hypotension.
Preliminary clinical evidence suggests that L-arginine enhances isoproterenol-induced vasodilation in patients with essential hypertension or a family history of essential hypertension.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically concomitant use of potassium-sparing diuretics with L-arginine may increases the risk of hyperkalemia.
Potassium-sparing diuretics can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and L-arginine might increase the risk for hypotension.
In vivo, concurrent use of L-arginine and sildenafil has resulted in increased vasodilation. Theoretically, concurrent use might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
Testosterone

Theoretically, concomitant use of L-arginine and testosterone might have additive effects.
In clinical research, L-arginine increases the level of testosterone in male patients with erectile dysfunction. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
L-Arginine Hydrochloride full monograph & interactions

Pine Bark Extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Clinical research suggests that maritime pine bark extract inhibits platelet aggregation. However, the clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
One clinical study shows that maritime pine bark extract decreases blood sugar in patients with diabetes being treated with antidiabetes agents. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
In vitro and animal research suggests that maritime pine bark extract has immunostimulant activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Pine Bark Extract full monograph & interactions

Saw Palmetto Berry Extract3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
Saw Palmetto Berry Extract full monograph & interactions

Pumpkin Seed Extract1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Pumpkin Seed Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Prostate-7, from the product label.

Confidence USA

See all Confidence USA products
Name
Confidence USA, Inc.
City
Port Washington
State
NY
ZipCode
11050
Phone Number
1-800-887-7161
Web Address
www.ConfidenceUSA.com
Pharmacist Counseling Corner

Prostate-7 by Confidence USA: Common Questions

Does Prostate-7 by Confidence USA interact with any medications?
Yes. Based on its ingredients, Prostate-7 has a known interaction with 1,102 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prostate-7 contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Prostate-7 if I'm on an antidepressant?
You need to check with your pharmacist first. DHEA, an ingredient in this product, can interact with antidepressants and theoretically increase the risk of psychiatric side effects, including a reported case of mania. This is a moderate-severity interaction that requires individual review of your specific medication.
What are the most common side effects of Prostate-7?
The most common side effects come from DHEA and include acne, headache, insomnia, mood changes, and nausea. Women may also experience increased body hair or voice deepening. Saw palmetto may cause abdominal pain, constipation, diarrhea, dizziness, or decreased sex drive. L-arginine can cause bloating, nausea, diarrhea, headache, or flushing.
Is Prostate-7 safe to take during pregnancy?
No. DHEA is rated possibly unsafe in pregnancy, and saw palmetto is rated likely unsafe. Pumpkin seed extract and tomato fruit extract have not been adequately studied in pregnancy. Do not take this product if you are pregnant; talk with your doctor about alternatives.
Can I take Prostate-7 while breastfeeding?
No, it's not recommended. DHEA and saw palmetto should be avoided while breastfeeding due to insufficient safety data. Pumpkin seed extract has not been well studied during breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you.
Does this product actually work for prostate health?
The evidence is mixed. Saw palmetto, one of the main ingredients, is rated possibly ineffective for benign prostatic hyperplasia (enlarged prostate)—the condition many people take it for. Pumpkin seed extract is rated possibly effective for the same condition. The other ingredients are not specifically rated for prostate health in our data.
What is DHEA and why is it in this product?
DHEA (dehydroepiandrosterone) is a hormone your body naturally produces. This supplement provides it in concentrated form. In research, DHEA has shown possibly effective evidence for depression and aging skin, and likely effective evidence for vaginal atrophy, though the prostate-specific benefit is not rated in our data. Because it's a hormone, it requires medical guidance and carries interaction risks.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prostate-7 label
Go deeper

The Full Monographs Behind Prostate-7’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Dhea

Interacts with 776 drugs

DHEA is a natural hormone that the body makes and that declines with age, and it is sold as a supplement claiming many benefits. The evidence is mixed and limited for most uses, and because...

Read the full Dhea monograph → Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph → Herb & supplement monograph

L-arginine

Interacts with 403 drugs

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for blood pressure, erectile dysfunction, and...

Read the full L-arginine monograph → Herb & supplement monograph

Maritime Pine

Interacts with 327 drugs

Maritime pine bark extract (often sold as Pycnogenol) is a plant-based antioxidant most studied for circulation, vein, and skin health. Some research is promising, but many studies are small...

Read the full Maritime Pine monograph → Herb & supplement monograph

Pumpkin

Interacts with 1 drug

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The evidence for these uses is limited and...

Read the full Pumpkin monograph → Herb & supplement monograph

Tomato

Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people. Concentrated tomato or lycopene supple...

Read the full Tomato monograph →
Sources

Sources & How We Checked

Prostate-7's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 208 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Dhea 98 references
  1. Frye RF, Kroboth PD, Folan MM, et al. Effect of DHEA on CYP3A-mediated metabolism of triazolam. Clin Pharmacol Ther 2000;67:109 (abstract PI-82).
  2. Kuritzky L. DHEA: Science or wishful thinking? Hosp Pract 1998;33:85-6. PubMed
  3. Van Vollenhoven RF, Morabito LM, Engleman EG, et al. Treatment of systemic lupus erythematosus with dehydroepiandrosterone: 50 patients treated up to 12 months. J Rheumatol 1998;25:285-9.
  4. Van Vollenhoven RF, Engleman EG, McGurie JL. Dehydroepiandrosterone in Systemic Lupus Erythematosus. Arth Rheum 1995;38:1826-31. DOI
  5. Ebeling P, Koivisto VA. Physiological importance of dehydroepiandrosterone. Lancet 1994;343:1479-81. PubMed
  6. Yen SS, Morales AJ, Khorram O. Replacement of DHEA in aging men and women. Potential remedial effects. Ann N Y Acad Sci 1995;774:128-42. PubMed
  7. Labrie F, Diamond P, Cusan L, et al. Effect of 12 month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women. J Clin Endocrinol Metab 1997;82:3498-505. PubMed
  8. Casson PR, Faquin LC, Stentz FB. Replacement of dehydroepiandrosterone enhances T-lymphocyte insulin binding in postmenopausal women. (abstract) Fertil Steril 1995;63:1027-31. DOI
  9. Morales AJ, Haubrich RH, Hwang JY, et al. The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women. Clin Endocrinol (Oxf)1 PubMed
  10. Arlt W, Justl H, Callies F, et al. Oral dehydroepiandrosterone for adrenal androgen replacement: pharmacokinetics and peripheral conversion to androgens and estrogens in young healthy females after dexamethasone suppression. [Abstract] J Clin Endocrinol PubMed
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Saw Palmetto 22 references
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Maritime Pine 14 references
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Pumpkin 5 references
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Tomato 3 references
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