Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Modelslim Ingredients & Drug Interactions

by Confidence USA

Modelslim label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Modelslim against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Modelslim is a dietary supplement by Confidence USA with 6 active ingredients. Its ingredients are commonly taken for constipation, irritable bowel syndrome (ibs), diarrhea.Based on those ingredients, 782 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Aloe vera leaf extract, American Ginseng Root Extract, Bacillus coagulans. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Modelslim by Confidence USA

Ask about any prescription or over-the-counter medication and we check it for interactions with Modelslim by Confidence USA — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Modelslim by Confidence USA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Modelslim Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,400 mg) without saying how much of each component you get.

Modelslim contains 6 active ingredients. Bacillus coagulans is a beneficial bacterium (probiotic) that may help with constipation and irritable bowel syndrome.

Apple cider vinegar is fermented apple juice. Aloe vera leaf extract comes from the aloe plant and is used for skin and digestive support.

Senna leaf extract is a plant-based laxative. Apple pectin is a fiber from apples.

American ginseng root extract is from the ginseng plant and may support immune function during upper respiratory infections. The product also contains inactive ingredients (fillers and capsule materials): bovine gelatin, titanium dioxide, FD&C Yellow #5, FD&C Blue #1, FD&C Red #3 Lake, rice flour, silicon dioxide, and magnesium stearate.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: promote healthy weight management.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (Prediabetes), Hyperlipidemia, Hypercholesterolemia, obesity, metabolic syndrome — and 1 related terms.
  • The strongest evidence on file: Pectin is rated "Possibly Effective" for Hypercholesterolemia (Natural Medicines).
  • Also on file: Aloe is rated "Possibly Effective" for Diabetes, Obesity.
  • Also on file: Pectin is rated "Insufficient Reliable Evidence To Rate" for Impaired glucose tolerance (Prediabetes).

Evidence varies by ingredient and claimed use. Aloe vera and senna leaf extract show possibly effective ratings for constipation.

Aloe vera is also rated possibly effective for obesity, diabetes, psoriasis, and burns. Apple pectin is rated possibly effective for high cholesterol.

Bacillus coagulans is rated possibly effective for constipation and irritable bowel syndrome. American ginseng is rated possibly effective for upper respiratory infections.

For other uses—such as antibiotic-associated diarrhea, athletic performance, cancer, fatty liver disease, prediabetes, and anemia—the evidence we hold is insufficient to rate effectiveness. Apple cider vinegar's effectiveness for acne, athletic performance, cognitive function, dental plaque, depression, or eczema is also not established in our data.

The evidence, ingredient by ingredient Bacillus Coagulans Apple Cider Vinegar Aloe Senna Pectin American Ginseng

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients are generally well tolerated at typical doses, but aloe vera and senna come with important caveats. Aloe latex (the yellow substance under the leaf) carries greater risk of serious side effects with long-term or high-dose use, including abdominal pain, diarrhea, and potentially low potassium levels.

Senna is considered safe for short-term occasional use but not for daily long-term use without medical advice; it can cause abdominal cramping, diarrhea, and with overuse, low potassium and increased bleeding risk. Apple cider vinegar at food amounts is generally well tolerated, but large or long-term medicinal doses may cause low potassium and bone loss.

Bacillus coagulans is generally well tolerated in healthy adults, though there is some concern about infection risk in severely ill or immunocompromised patients. American ginseng is generally well tolerated short-term, but long-term safety is not well studied, and headache has been reported.

Pectin from food and typical supplements is well tolerated, though allergic reactions are rare.

Side effects, ingredient by ingredient Bacillus Coagulans Apple Cider Vinegar Aloe Senna Pectin American Ginseng

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Pectin, Aloe, Senna, Apple Cider Vinegar, American Ginseng, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications.
  • For scale: 782 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking Modelslim if you use warfarin or other blood thinners, digoxin or other heart medications, diabetes drugs, diuretics, antibiotics (especially tetracyclines), immunosuppressants, lovastatin, or older antidepressants (MAOIs). Potassium loss is a recurring risk across multiple ingredients when combined with certain drugs, so electrolyte monitoring may be needed.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Modelslim may appeal to people looking for digestive or weight-support help, but it's not a simple add-on if you take heart, blood-thinning, or diabetes medications—the warfarin and digoxin interactions are particularly serious. Before you start, pull out your medication list and run each drug through the interaction checker on this page with your pharmacist or doctor, especially if you take blood thinners, heart medications, diabetes drugs, diuretics, antibiotics, or immunosuppressants.

Pregnancy and breastfeeding safety information is limited for most ingredients; talk it over with your doctor or pharmacist if you're planning to become pregnant, are pregnant, or are nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Modelslim, straight from the product label.

Brand Confidence USA
Barcode (UPC) 892483001021
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 283354
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Modelslim by Confidence USA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
892483001021
IngredientAmount% DV
Bacillus coagulans0 NP--
Apple Cider Vinegar0 NP--
Aloe vera leaf extract0 NP--
Senna leaf extract0 NP--
Apple Pectin, Powder0 NP--
Modelslim Proprietary Blend1400 mg--
American Ginseng Root Extract0 NP--

Other ingredients: Bovine Gelatin, Titanium Dioxide, FD&C Yellow #5, FD&C Blue #1, FD&C Red #3 Lake, Rice Flour, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: For adults 18 years of age and older.

If you are pregnant, nursing or taking any medications, consult your physician before using this product.

Discontinue use and contact your physician if any adverse reactions occur.

Keep out of reach of children.

If outer safety seal is broken or missing, do not consume.

Formula

Modelslim contains a proprietary combination of ingredients that have been shown to help promote healthy weight management. Key ingredients include Apple Cider Vinegar, Aloe Vera Leaf and American Ginseng Root, which research suggests can help support healthy weight management and healthy diet.

Modelslim with Apple Cider Vinegar

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Modelslim is manufactured by Confidence USA, Inc., an FDA registered manufacturer following strict current Good Manufacturing Practices. (FDA Registration# 10362791850 - Product Code# FP0561)

Made in USA

Seals/Symbols

Good Manufacturing Product GMP

Brand IP Statement(s)

Confidence USA Better Products for a Better Life

General Statements

New Formula

Other Countries: 001-516-767-1860 For more info and reorders: www.ConfidenceUSA.com

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adult - Take 2 capsules daily as dietary supplement. Do not exceed 4 capsules per day.

Storage

Store at room temperature, with lid tightly closed.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Modelslim by Confidence USA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Modelslim label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Modelslim by Confidence USA

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Bovine Gelatin, Titanium Dioxide, FD&C Yellow #5, FD&C Blue #1, FD&C Red #3 Lake, Rice Flour, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Modelslim by Confidence USA Drug Interactions

Want to check YOUR meds against Modelslim?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
782Drugs
3 Major 655 Moderate 124 Minor

Ingredients driving the most interactions

Aloe vera leaf extract 461
American Ginseng Root Extract 217
Bacillus coagulans 182
Apple Cider Vinegar 162
Senna leaf extract 140

Individual Drug Interactions

The ingredients in Modelslim interact with 782 drugs. Click any drug to see the details.

6 of the 6 ingredients in Modelslim interact with drugs. Each result below shows which ingredient is responsible. Aloe vera leaf extract American Ginseng Root Extract Bacillus coagulans Apple Cider Vinegar Senna leaf extract Apple Pectin, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Modelslim with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Aloe vera leaf extract7 drug types · 461 drugs

Digoxin (Lanoxin)

Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.

Likelihood Possible Evidence D
Antidiabetes Drugs

Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.

Likelihood Possible Evidence D
Stimulant Laxatives

Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Aloe vera leaf extract full monograph & interactions

American Ginseng Root Extract4 drug types · 217 drugs

Warfarin (Coumadin)

American ginseng seems to decrease the effectiveness of warfarin therapy.
Healthy patients receiving warfarin 5 mg daily, who also take American ginseng 1 gram twice daily, seem to have a significantly reduced international normalized ratio (INR).

Likelihood Likely Evidence B
Antidiabetes Drugs

Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
American ginseng seems to lower postprandial blood glucose. Theoretically, concomitant use with antidiabetes drugs might enhance blood glucose lowering effects and possibly cause hypoglycemia.

Likelihood Probable Evidence B
Immunosuppressants

Theoretically, American ginseng use might interfere with immunosuppressive therapy.
American ginseng seems to stimulate immune function. Theoretically, American ginseng might decrease the effectiveness of immunosuppressant drugs.

Likelihood Possible Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, American ginseng can interfere with MAOI therapy.
There is one case report of insomnia, headache, and tremors when an unspecified ginseng product was used with phenelzine (Nardil), an MAOI. There is also one case report of hypomania when an unspecified ginseng product was used with phenelzine. Theoretically, American ginseng may interfere with MAOI therapy.

Likelihood Possible Evidence D
American Ginseng Root Extract full monograph & interactions

Bacillus coagulans1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
Bacillus coagulans full monograph & interactions

Apple Cider Vinegar4 drug types · 162 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.

Likelihood Possible Evidence D
Insulin

Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.

Likelihood Possible Evidence B
Apple Cider Vinegar full monograph & interactions

Senna leaf extract5 drug types · 140 drugs

Digoxin (Lanoxin)

Theoretically, senna might increase the risk of adverse effects when taken with digoxin.
Overuse/abuse of senna increases the risk of adverse effects from cardiac glycosides, such as digoxin, due to potassium depletion.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of senna might compound diuretic-induced potassium loss and increase the risk for hypokalemia.

Likelihood Possible Evidence D
Estrogens

Theoretically, taking senna may interfere with the absorption of exogenous estrogens.
Some preliminary clinical evidence suggests that senna reduces the absorption of estradiol and decreases serum concentrations of estrone and estrone sulfate by decreasing intestinal transit time.

Likelihood Possible Evidence B
Stimulant Laxatives

Theoretically, senna might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Senna is a stimulant laxative; concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, excessive use of senna might increase the effects of warfarin.
Senna has stimulant laxative effects and can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. In one case report, excessive use of senna for 3 weeks resulted in diarrhea, bloody stools, and an elevated INR of 11.9.

Likelihood Possible Evidence D
Senna leaf extract full monograph & interactions

Apple Pectin, Powder3 drug types · 23 drugs

Digoxin (Lanoxin)

Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.

Likelihood Possible Evidence B
Lovastatin (Mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.

Likelihood Possible Evidence B
Apple Pectin, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Modelslim, from the product label.

Confidence USA

See all Confidence USA products
Name
Confidence USA, INC.
City
Port Washington
State
NY
ZipCode
11050
Phone Number
1-800-887-7161
Web Address
ConfidenceUSA.com
Pharmacist Counseling Corner

Modelslim by Confidence USA: Common Questions

Does Modelslim by Confidence USA interact with any medications?
Yes. Based on its ingredients, Modelslim has a known interaction with 782 medications, including 3 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Modelslim contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work for weight loss?
Aloe vera is rated possibly effective for obesity in our data. The other ingredients support digestion or general health, but we don't hold effectiveness ratings for weight loss for most of them. Talk to your doctor about whether Modelslim fits your goals.
Can I take Modelslim if I'm on warfarin?
No, not without close supervision from your doctor. American ginseng in this product significantly reduces warfarin's effectiveness, lowering your protection against clots. You'd need your doctor to monitor your clotting levels closely and adjust your warfarin dose if you take this product together.
Is it safe to take while pregnant?
Safety data is limited or not ideal for pregnancy. Aloe vera is rated possibly unsafe in pregnancy because it may stimulate the uterus and act as a strong laxative. American ginseng is also rated possibly unsafe. Talk to your doctor or pharmacist before using Modelslim if you're pregnant or planning to become pregnant.
What is Bacillus coagulans and why is it in here?
Bacillus coagulans is a beneficial bacterium—a probiotic—that may help with constipation and irritable bowel syndrome. If you're taking antibiotics, separate them from this product by a few hours, because antibiotics can kill off the beneficial bacteria.
Can I take this with my diabetes medication?
Not without checking first. Aloe vera, apple cider vinegar, and American ginseng can all lower blood sugar, and when combined with diabetes drugs they may increase the risk of low blood sugar (hypoglycemia). Talk to your doctor before adding Modelslim to your diabetes routine.
Are there any fillers in this?
Yes, the capsule contains several inactive ingredients including bovine gelatin, rice flour, titanium dioxide, and food dyes (FD&C Yellow #5, Blue #1, and Red #3 Lake), along with silicon dioxide and magnesium stearate.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Modelslim label
Go deeper

The Full Monographs Behind Modelslim’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph → Herb & supplement monograph

Apple Cider Vinegar

Interacts with 162 drugs

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...

Read the full Apple Cider Vinegar monograph → Herb & supplement monograph

Aloe

Interacts with 461 drugs

Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a strong laxative that can cause cramping and...

Read the full Aloe monograph → Herb & supplement monograph

Senna

Interacts with 140 drugs

Senna is a plant-based stimulant laxative that is widely used and generally effective for short-term relief of constipation. It is best used occasionally and for only a few days at a time, s...

Read the full Senna monograph → Herb & supplement monograph

Pectin

Interacts with 23 drugs

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...

Read the full Pectin monograph → Herb & supplement monograph

American Ginseng

Interacts with 217 drugs

American ginseng is an herbal root used as an 'adaptogen' to support energy, stress, immune function, and blood sugar. Some uses—such as reducing the chance or length of colds and modestly l...

Read the full American Ginseng monograph →
Sources

Sources & How We Checked

Modelslim's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 137 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
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See these in context on the Bacillus Coagulans monograph →

Apple Cider Vinegar 11 references
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See these in context on the Apple Cider Vinegar monograph →

Aloe 41 references
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See these in context on the Aloe monograph →

Senna 42 references
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See these in context on the Senna monograph →

Pectin 11 references
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See these in context on the Pectin monograph →

American Ginseng 12 references
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See these in context on the American Ginseng monograph →

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