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Dietary supplement

Corn Silk Ingredients & Drug Interactions

by Hawaii Pharm

Corn Silk label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Corn Silk against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Corn Silk is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for urinary tract and bladder problems, mild fluid retention (diuretic), kidney and prostate concerns.Based on those ingredients, 290 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Corn Silk extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Corn Silk by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Corn Silk by Hawaii Pharm — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Corn Silk by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Hawaii Pharm's Corn Silk contains one active ingredient: certified organic corn silk extract. This is the silky fibers that grow inside the corn husk, made into a liquid form using vegetable glycerin, alcohol, and purified water.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Urinary tract and kidney health support.
  • We looked for evidence on: Urinary tract infections (UTIs), Kidney stones (nephrolithiasis), Nocturnal enuresis, Prostatitis, Bladder function, Fluid retention — and 2 related terms.
  • The closest evidence on file: Corn Silk is rated "Insufficient Reliable Evidence To Rate" for Kidney stones (nephrolithiasis) (Natural Medicines).
  • Also on file: Corn Silk is rated "Insufficient Reliable Evidence To Rate" for Prostatitis, Urinary tract infections (UTIs), Nocturnal enuresis.

The evidence we have for corn silk is limited. We hold no established effectiveness ratings for angina, heart disease, heart failure, depression, diabetes, or fatigue — the data simply isn't there to support a clear claim either way.

What research exists is mostly animal studies or small human trials; we'd need more robust clinical evidence before we could say it works for any of these conditions.

The evidence, ingredient by ingredient Corn Silk

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Corn silk is generally well tolerated for short-term use, but human safety data are thin on the ground. The most common side effects with oral use are low potassium (hypokalemia) and low sodium (hyponatremia), especially with longer-term use.

Applied to skin, it can occasionally cause rash or hives. During pregnancy, the safety data aren't strong enough — it's best avoided unless your doctor says otherwise.

While breastfeeding, we don't have enough information to know either way; talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Corn Silk

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Corn Silk.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 290 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check your list if you're on blood pressure medications, steroids, diabetes medications, diuretics (water pills), or warfarin. All of these have documented Moderate interactions with corn silk extract.

Run them through the checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Corn Silk might be worth considering if you're looking for a traditional remedy, but the evidence for its effectiveness isn't established yet. If you take blood pressure meds, diabetes drugs, steroids, water pills, or warfarin, you absolutely need to check this with your pharmacist first — the interactions are real.

Pregnant or breastfeeding? Check with your doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Corn Silk, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 650905486920
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 23, 2020
DSLD ID 237936
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Corn Silk by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
650905486920
IngredientAmount% DV
certified organic Corn Silk extract970 mg--

Other ingredients: Vegetable Palm Glycerin, pharmaceutical grade Alcohol, artesian Hawaiian purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no GMO, gluten, artificial colors, heavy metals, preservatives, pesticides, fertilizers.

Super concentrated liquid herbal extract. Dry herb/menstruum ratio: 1:3.

Manufactured in an FDA registered facility.

Non GMO Gluten free

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops (0.7-1 ml, one full squeeze of the dropper bulb) to 2-4 oz of juice or water up to 4 times per day.

Precautions

Warning: Keep out of the reach of children.

May have contraindications. We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing or taking any medications.

Do not use if seal is broken or missing.

Storage

Store in a cool dry place.

Formula

(Zea mays)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Corn Silk by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Corn Silk label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Corn Silk by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Certified organic Corn Silk extract

Interacts with
290 drugs
970 mg per serving

Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence...

Certified organic Corn Silk extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Pharmaceutical grade Alcohol, Artesian Hawaiian purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Corn Silk by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Corn Silk?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
290Drugs
290 Moderate

Ingredients driving the most interactions

certified organic Corn Silk extract 290

Individual Drug Interactions

The ingredients in Corn Silk interact with 290 drugs. Click any drug to see the details.

1 of the 1 ingredient in Corn Silk interact with drugs. Each result below shows which ingredient is responsible. certified organic Corn Silk extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Corn Silk with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Corn Silk extract5 drug types · 290 drugs

Antidiabetes Drugs

Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research in diabetic mice shows that taking corn silk extract lowers fasting blood glucose levels.

Likelihood Possible Evidence D
Antihypertensive Drugs

Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Clinical research in both hypertensive and normotensive adults shows that taking corn silk extract lowers systolic and diastolic blood pressure.

Likelihood Possible Evidence D
Corticosteroids

Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Clinical research shows that taking corn silk extract increases the urinary excretion of potassium.

Likelihood Possible Evidence D
Diuretic Drugs

Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Clinical research shows that taking corn silk extract increases urine volume and promotes the urinary excretion of sodium and potassium. Some patients may require electrolyte supplementation.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Corn silk contains vitamin K. Individuals taking warfarin should consume a consistent daily amount of corn silk to maintain consistent anticoagulation.

Likelihood Likely Evidence D
certified organic Corn Silk extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Corn Silk, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Corn Silk by Hawaii Pharm: Common Questions

Does Corn Silk by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Corn Silk has a known interaction with 290 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Corn Silk contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is corn silk safe to take long-term?
Human safety data are limited, especially over the long haul. The most common concern with extended use is low potassium and low sodium levels. If you're thinking about long-term use, talk with your pharmacist or doctor first.
Can I take this while pregnant?
The safety data aren't strong enough to call it safe during pregnancy, so it's best avoided unless your doctor approves. There simply isn't enough reliable information.
Can I take this while breastfeeding?
We don't have enough information to know whether it's safe while breastfeeding. Talk with your doctor or pharmacist — they can help you weigh the pros and cons for your situation.
What does corn silk actually do?
Research shows it can lower blood pressure and blood sugar and increase urine output — which is partly why it interacts with so many medications. But we don't have enough evidence yet to say it reliably treats any specific condition.
What are the side effects?
Serious side effects are rare, but low potassium and low sodium are the most common with oral use, especially over time. If you use it on your skin, it can occasionally cause a rash or hives.
Does this product have fillers?
Yes — it contains vegetable glycerin, alcohol, and purified water as inactive ingredients to make it a liquid.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Corn Silk is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Corn Silk label
Go deeper

The Full Monographs Behind Corn Silk’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Corn Silk

Interacts with 290 drugs

Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence for these uses is limited, so it should...

Read the full Corn Silk monograph →
Sources

Sources & How We Checked

Corn Silk's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Corn Silk 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. George GO, Idu FK. Corn silk aqueous extracts and intraocular pressure of systemic and non-systemic hypertensive subjects. Clin Exp Optom. 2015 Mar;98(2):138-49. PubMed
  4. Sheng L, Chen Q, Di L, Li N. Evaluation of anti-diabetic potential of corn silk in high-fat diet/streptozotocin- induced type 2 diabetes mice model. Endocr Metab Immune Disord Drug Targets. 2020. PubMed

See these in context on the Corn Silk monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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