D-Mannose 1500 mg Ingredients & Drug Interactions
by Nutracraft
What is this page for?
First and foremost: checking D-Mannose 1500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
D-Mannose 1500 mg is a dietary supplement by Nutracraft with 1 active ingredient. Its ingredients are commonly taken for preventing urinary tract infections (utis), treating mild utis, urinary tract health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of D-Mannose 1500 mg by Nutracraft
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: D-mannose, a simple sugar your body doesn't fully absorb. It passes mostly through your urine, where it may help with certain conditions.
The capsule also contains inactive ingredients — hydroxypropyl methylcellulose, magnesium stearate, and silicon dioxide — which are fillers and binders used to hold the capsule together.
Does it work?
Leans against
D-mannose is likely effective for carbohydrate-deficient glycoprotein syndrome type 1b, a rare metabolic condition. For urinary tract infections (UTIs), the evidence suggests it's possibly ineffective — meaning the data don't show it works well for that purpose, despite what you might see claimed online.
How safe is it?
Well-documented data
D-mannose is generally well tolerated in the short term, though long-term safety data are limited. The most common side effects are bloating, diarrhea, loose stools, and nausea — and higher doses (especially over 200 mg per kilogram of body weight in a single dose) are more likely to trigger osmotic diarrhea.
The safety data during pregnancy aren't robust enough to recommend it without talking to your doctor first. Breastfeeding safety hasn't been well studied either, so caution is advised if you're nursing.
Meds to double-check
No known interactions
No interactions are documented for D-mannose in our data. That doesn't mean none exist, so run your medications through the checker on this page or ask us before you start.
The bottom line
Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
D-mannose may help if you have the rare genetic condition carbohydrate-deficient glycoprotein syndrome type 1b. If you're thinking of taking it for UTIs, the evidence doesn't support that use.
Pregnant or breastfeeding? Talk to your doctor or pharmacist before starting — the safety data aren't solid enough to go it alone.
Watch for bloating and diarrhea, especially at higher doses.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about D-Mannose 1500 mg, straight from the product label.
| Brand | Nutracraft |
|---|---|
| Barcode (UPC) | X000J5UILZ |
| Net contents | 90 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 329241 |
| Product type | Fiber And Other Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for D-Mannose 1500 mg by Nutracraft, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| D-Mannose | 1500 mg | -- |
Other ingredients: Hydroxypropyl Methylcellulose, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: 3 capsules taken 1 to 2 times daily preferably with meals or as directed by a healthcare professional.
Precautions
Caution: Food supplements should not be used as a substitute for a varied diet. Do not exceed recommended dose.
Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any food supplement.
Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any food supplement.
This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.
Keep out of the reach of children.
Do not use if safety seal is damaged or missing.
General Statements
Get your coupon code and bonus products here: www.nutracraft.com/coupon Please recycle.
Formulation
Support urinary tract health
Formula
D-mannose 1500 mg per serve
FDA Statement of Identity
Food Supplement
Storage
Store in a cool, dry place.
Seals/Symbols
Formulated in USA Sourced from a GMP Certified Facility
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
D-Mannose 1500 mg by Nutracraft label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in D-Mannose 1500 mg by Nutracraft
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Vegetable Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
D-Mannose
No knowninteractions
D-mannose is a natural sugar most often used to help prevent urinary tract infections, especially those caused by E. coli. Early research is promising...
D-Mannose monograph & interactionsOther (inactive) ingredients: Hydroxypropyl Methylcellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
D-Mannose 1500 mg by Nutracraft Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in D-Mannose 1500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for D-Mannose 1500 mg, from the product label.
Nutracraft
See all Nutracraft products- Name
- Leverage Media Ltd.
- Street Address
- Davenport House 261 Bolton Rd
- City
- Bury Lancashire
- ZipCode
- BL8 2NZ
D-Mannose 1500 mg by Nutracraft: Common Questions
Does D-Mannose 1500 mg by Nutracraft interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take D-mannose if I'm pregnant?
Is D-mannose safe while breastfeeding?
Will D-mannose help my UTI?
What side effects should I expect?
How long can I safely take D-mannose?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if D-Mannose 1500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind D-Mannose 1500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
D-Mannose 1500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
D-mannose 6 references
- Westphal V, Kjaergaard S, Davis JA, et al. Genetic and metabolic analysis of the first adult with congenital disorder of glycosylation type Ib: long-term outcome and effects of mannose supplementation. Mol Genet Metab 2001;73:77-85. PubMed
- Kranjcec B, Papes D, Altarac S. D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J Urol. 2014 Feb;32(1):79-84.
- de Lonlay P, Seta N. The clinical spectrum of phosphomannose isomerase deficiency, with an evaluation of mannose treatment for CDG-Ib. Biochim Biophys Acta. 2009;1792(9):841-3. PubMed
- Harms HK, Zimmer KP, Kurnik K, Bertele-Harms RM, Weidinger S, Reiter K. Oral mannose therapy persistently corrects the severe clinical symptoms and biochemical abnormalities of phosphomannose isomerase deficiency. Acta Paediatr. 2002;91(10):1065-72. DOI
- . Damen G, de Klerk H, Huijmans J, den Hollander J, Sinaasappel M. Gastrointestinal and other clinical manifestations in 17 children with congenital disorders of glycosylation type Ia, Ib, and Ic. J Pediatr Gastroenterol Nutr. 2004;38(3):282-7. DOI
- Lenger SM, Bradley MS, Thomas DA, Bertolet MH, Lowder JL, Sutcliffe S. D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis. Am J Obstet Gynecol. 2020;223(2):265.e1-265.e13. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC