No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

D-Mannose 1500 mg Ingredients & Drug Interactions

by Nutracraft

Capsule Category: Fiber And Other Nutrients
No known interaction
The interaction bottom line No known interaction

D-Mannose 1500 mg is a dietary supplement by Nutracraft with 1 active ingredient. Its ingredients are commonly taken for preventing urinary tract infections (utis), treating mild utis, urinary tract health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of D-Mannose 1500 mg by Nutracraft

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-mannose, a simple sugar (carbohydrate) that your body can use or pass out in urine. The capsule also contains inactive ingredients — hydroxypropyl methylcellulose (a capsule material), vegetable magnesium stearate (a binder), and silicon dioxide (an anti-caking agent).

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Support urinary tract and bladder health.
  • We looked for evidence on: Urinary tract infections (UTIs), Cystitis, Urinary tract health, Bladder health.
  • The closest evidence on file: D-mannose is rated "Possibly Ineffective" for Urinary tract infections (UTIs) (Natural Medicines).

The evidence for D-mannose is mixed. For carbohydrate-deficient glycoprotein syndrome type 1b (a rare inherited disorder), it is likely effective.

For urinary tract infections (UTIs), the data suggests it's possibly ineffective — meaning current evidence doesn't support its use for that purpose, though research is ongoing.

The evidence, ingredient by ingredient D-mannose

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

D-mannose is generally well tolerated in the short term, but long-term safety data are limited, so we can't say how it holds up with months or years of daily use. The most common side effects are bloating, diarrhea, nausea, and loose stools.

Higher doses (more than 200 mg per kilogram of body weight in a single dose) are more likely to trigger osmotic diarrhea. Diarrhea has been reported in adults taking 2 grams daily for 6 months.

There isn't enough reliable safety data during pregnancy, so the evidence advises against it unless your doctor advises otherwise. Safety while breastfeeding is not well studied, so caution is advised — talk with your doctor or pharmacist about whether it's right for you.

Side effects, ingredient by ingredient D-mannose

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for D-mannose in our data. That said, confirm with your own doctor or pharmacist before adding this to your routine — they can review your complete medication and supplement list.

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

D-mannose may be worth considering if you have carbohydrate-deficient glycoprotein syndrome type 1b and your doctor recommends it. If you're thinking about it for UTIs, the current evidence doesn't support that use.

Be prepared for possible bloating, diarrhea, or nausea, especially at higher doses. Talk with your own doctor or pharmacist before starting, especially if you're pregnant, breastfeeding, or taking any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Mannose 1500 mg, straight from the product label.

Brand Nutracraft
Barcode (UPC) X000ZLYBAZ
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 246484
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Mannose 1500 mg by Nutracraft, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Vegetable Capsule(s)
Maximum serving Sizes:
3 Vegetable Capsule(s)
Servings per container
30
UPC/BARCODE
X000ZLYBAZ
IngredientAmount% DV
D-Mannose1500 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Vegetable Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: 3 capsules taken 1 to 2 times preferably with meals or as directed by a healthcare professional.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Lot # and expiration date printed on bottom of bottle.

Please recycle.

Get your coupon code and bonus products here: www.nutracraft.com/coupon

Formulation

Support urinary tract health Supports bladder health

Vegetarian capsule

Formulated in USA Good Manufacturing Practice Sourced from a GMP Certified Facility Quality Assured

Formula

1,500 mg per serve D-mannose 1500 mg per serving

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place.

Seals/Symbols

Formulated in USA

Good Manufacturing Practice Sourced from a GMP Certified Facility Quality Assured

See for yourself

D-Mannose 1500 mg by Nutracraft label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in D-Mannose 1500 mg by Nutracraft

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Vegetable Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

D-Mannose

No known
interactions
1500 mg per serving

D-mannose is a natural sugar most often used to help prevent urinary tract infections, especially those caused by E. coli. Early research is promising...

D-Mannose monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Vegetable Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Mannose 1500 mg by Nutracraft Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in D-Mannose 1500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for D-Mannose 1500 mg, from the product label.

Nutracraft

See all Nutracraft products
Name
Nutracraft.com
Street Address
9450 SW Gemini Dr. #62487
City
Beaverton
State
OR
Phone Number
97008-7105
Web Address
nutracraft.com
Pharmacist Counseling Corner

D-Mannose 1500 mg by Nutracraft: Common Questions

Does D-Mannose 1500 mg by Nutracraft interact with any medications?
We do not currently list a known interaction for the mapped ingredients in D-Mannose 1500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
D-Mannose 1500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will D-mannose help my UTI?
Current evidence suggests D-mannose is possibly ineffective for urinary tract infections. If you're dealing with a UTI, talk with your doctor about proven treatments rather than relying on this supplement.
What side effects might I notice?
The most common are bloating, diarrhea, nausea, and loose stools. Higher doses make diarrhea more likely. If these bother you, mention them to your pharmacist — they can advise on dose adjustments or whether to stop.
Is it safe to take long-term?
D-mannose is well tolerated short-term, but we don't have enough high-quality long-term safety data. If you're thinking about taking it for months or years, discuss that plan with your doctor first.
Can I take it if I'm pregnant?
There isn't enough reliable safety data during pregnancy, so the evidence advises against it unless your doctor advises otherwise. Talk with your doctor about whether it's appropriate for you.
What is D-mannose, and what does it do in my body?
D-mannose is a simple sugar your body can use for energy or filter out through your urine. It's the active ingredient here and is used to treat certain rare inherited disorders — not everyday conditions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Mannose 1500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Mannose 1500 mg label
Go deeper

The Full Monographs Behind D-Mannose 1500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

D-Mannose 1500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

D-mannose 6 references
  1. Westphal V, Kjaergaard S, Davis JA, et al. Genetic and metabolic analysis of the first adult with congenital disorder of glycosylation type Ib: long-term outcome and effects of mannose supplementation. Mol Genet Metab 2001;73:77-85. PubMed
  2. Kranjcec B, Papes D, Altarac S. D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J Urol. 2014 Feb;32(1):79-84.
  3. de Lonlay P, Seta N. The clinical spectrum of phosphomannose isomerase deficiency, with an evaluation of mannose treatment for CDG-Ib. Biochim Biophys Acta. 2009;1792(9):841-3. PubMed
  4. Harms HK, Zimmer KP, Kurnik K, Bertele-Harms RM, Weidinger S, Reiter K. Oral mannose therapy persistently corrects the severe clinical symptoms and biochemical abnormalities of phosphomannose isomerase deficiency. Acta Paediatr. 2002;91(10):1065-72. DOI
  5. . Damen G, de Klerk H, Huijmans J, den Hollander J, Sinaasappel M. Gastrointestinal and other clinical manifestations in 17 children with congenital disorders of glycosylation type Ia, Ib, and Ic. J Pediatr Gastroenterol Nutr. 2004;38(3):282-7. DOI
  6. Lenger SM, Bradley MS, Thomas DA, Bertolet MH, Lowder JL, Sutcliffe S. D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis. Am J Obstet Gynecol. 2020;223(2):265.e1-265.e13. PubMed

See these in context on the D-mannose monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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