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Dietary supplement

D-Ribose 750 mg Ingredients & Drug Interactions

by NOW Sports

D-Ribose 750 mg label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D-Ribose 750 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

D-Ribose 750 mg is a dietary supplement by NOW Sports with 1 active ingredient. Its ingredients are commonly taken for energy and fatigue, athletic performance and recovery, fibromyalgia symptoms.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bioenergy Ribose. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against D-Ribose 750 mg by NOW Sports

Ask about any prescription or over-the-counter medication and we check it for interactions with D-Ribose 750 mg by NOW Sports — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of D-Ribose 750 mg by NOW Sports

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Bioenergy Ribose, a five-carbon sugar your cells use to make energy. The capsule also includes two inactive ingredients — hypromellose and stearic acid — which help form and stabilize the capsule.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: energy and athletic performance.
  • We looked for evidence on: Athletic performance, Chronic fatigue syndrome (CFS), Fibromyalgia, Congestive heart failure (CHF), Coronary heart disease (CHD), Coronary artery bypass graft (CABG) surgery — and 3 related terms.
  • The closest evidence on file: Ribose is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Ribose is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD), Chronic fatigue syndrome (CFS), Congestive heart failure (CHF), Fibromyalgia, and more.

The evidence for ribose's effectiveness is mixed and limited. For athletic performance and McArdle disease, it's rated possibly ineffective.

For restless legs syndrome, muscle soreness, heart failure, and recovery after heart surgery, there isn't enough reliable evidence to rate it either way. In other words, we don't have solid data showing it works for any of these conditions.

The evidence, ingredient by ingredient Ribose

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ribose is generally well tolerated in the short term — up to about a month in studies — but long-term safety hasn't been well studied, so caution is warranted if you're thinking of using it long-term. The most common side effects are gastrointestinal: diarrhea, nausea, and stomach discomfort.

Headache, low blood sugar, increased appetite, lightheadedness, and mild anxiety have also been reported; lowering the dose has resolved these symptoms in some cases. There isn't enough safety information to recommend ribose during pregnancy or while breastfeeding.

If you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist before using this product.

Side effects, ingredient by ingredient Ribose

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ribose.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your exact medications if you take insulin or any antidiabetes drugs (such as metformin, glyburide, or empagliflozin). Both carry a Moderate risk of increased low blood sugar when combined with ribose.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

D-Ribose might interest athletes or people with certain muscle disorders, but the evidence for its effectiveness is weak or absent. The real concern is blood sugar — if you take insulin or any diabetes medication, you need to check this product with your pharmacist first.

Stick to short-term use, and watch for stomach upset or low blood sugar symptoms.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Ribose 750 mg, straight from the product label.

Brand NOW Sports
Barcode (UPC) 733739021458
Net contents 120 Veg Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 335344
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Ribose 750 mg by NOW Sports, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veg Capsule(s)
Maximum serving Sizes:
6 Veg Capsule(s)
Servings per container
20
UPC/BARCODE
733739021458
IngredientAmount% DV
Calories20 Calorie(s)--
Total Carbohydrates4.5 Gram(s)2%
Bioenergy Ribose4.5 Gram(s)--
Total Sugars4.5 Gram(s)--

Other ingredients: Hypromellose, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Take 2-6 capsules daily, prior to exercise.

Formula

Ribose is a simple sugar that occurs naturally in all living cells. Ribose is the structural backbone of ATP, the primary form of energy used for all cellular processes. Demand for ATP availability is especially critical in the heart and skeletal muscle and Ribose supplementation can help to maintain optimal energy levels in these tissues.

Bioenergy RIBOSE

Triangle K (Kosher)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only. Keep out of reach of children.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Natural color variation may occur in this product.

Energy production Sports recovery Muscle fuel ATP production

Vegan

Steroid tested Non-GMO Project Verified nongmoproject.org

Made and quality tested in the USA with globally sourced ingredients.

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.

Storage

Store in a cool, dry, dark place after opening.

Seals/Symbols

GMP Quality Assured Informed Sport We Test - You Trust Steroid Tested V Vegan Triangle K (Kosher) Non-GMO Project Verified nongmoproject.org

FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Bioenergy RIBOSE is a registered trademark of Bioenergy Life Science, Inc. Use of ribose is licensed by Bioenergy Life Science, Inc. under U.S. patents and foreign patents issued and pending.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D-Ribose 750 mg by NOW Sports label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D-Ribose 750 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D-Ribose 750 mg by NOW Sports

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Veg Capsule(s) Dosage formCapsule Servings per container20 Amounts shown are per serving.

Bioenergy Ribose

Interacts with
86 drugs
4.5 Gram(s) per serving Form: D-Ribose, Powder

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalg...

Bioenergy Ribose monograph & interactions

Other (inactive) ingredients: Hypromellose, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Ribose 750 mg by NOW Sports Drug Interactions

Want to check YOUR meds against D-Ribose 750 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Bioenergy Ribose 86

Individual Drug Interactions

The ingredients in D-Ribose 750 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in D-Ribose 750 mg interact with drugs. Each result below shows which ingredient is responsible. Bioenergy Ribose

Each ingredient & the kinds of drugs it affects

For each ingredient in D-Ribose 750 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bioenergy Ribose2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, taking ribose in combination with antidiabetes drugs might increase the risk of hypoglycemia.
In clinical research, ribose decreases serum glucose levels in a dose-dependent manner.

Likelihood Probable Evidence B
Insulin

Theoretically, taking ribose with insulin could increase the hypoglycemic effect of insulin.
In clinical pharmacokinetic studies, oral administration of ribose modestly increased serum insulin levels.

Likelihood Possible Evidence B
Bioenergy Ribose full monograph & interactions
The maker

Brand information

Manufacturer and brand details for D-Ribose 750 mg, from the product label.

NOW Sports

See all NOW Sports products
Name
NOW FOODS
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowsportsproducts.com
Pharmacist Counseling Corner

D-Ribose 750 mg by NOW Sports: Common Questions

Does D-Ribose 750 mg by NOW Sports interact with any medications?
Yes. Based on its ingredients, D-Ribose 750 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
D-Ribose 750 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will D-Ribose help my athletic performance?
The evidence suggests it's not effective for athletic performance. Studies don't support using it to boost endurance or strength.
What are the most common side effects?
Diarrhea, stomach discomfort, nausea, and headache are the most common. A small number of people also reported mild anxiety or lightheadedness. Lowering your dose has resolved nausea and anxiety in some cases.
Is it safe to take D-Ribose long-term?
Studies only show it's well tolerated for up to about a month. Long-term safety hasn't been well studied, so we don't have solid data on what happens with regular use over months or years.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety information to recommend it during pregnancy or breastfeeding. Talk with your doctor or pharmacist for personalized advice.
Why does this product interact with blood sugar medications?
Ribose lowers blood glucose levels on its own. If you're already taking a medication that does the same thing, your blood sugar could drop too low.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Ribose 750 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Ribose 750 mg label
Go deeper

The Full Monographs Behind D-Ribose 750 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ribose

Interacts with 86 drugs

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalgia, exercise recovery, or heart conditio...

Read the full Ribose monograph →
Sources

Sources & How We Checked

D-Ribose 750 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ribose 8 references
  1. Segal S, Foley J. The metabolism of D-ribose in man. J Clin Invest 1958;37:719-35. PubMed
  2. Perlmutter NS, Wilson RA, Angello DA, et al. Ribose facilitates thallium-201 redistribution in patients with coronary artery disease. J Nucl Med 1991;32:193-200.
  3. Hegewald MG, Palac RT, Angello DA, et al. Ribose infusion accelerates thallium redistribution with early imaging compared with late 24-hour imaging without ribose. J Am Coll Cardiol 1991;18:1671-81. PubMed
  4. Pliml W, von Arnim T, Stalein A, et al. Effects of ribose on excercise-induced ischaemia in stable coronary artery disease. Lancet 1992;340:507-10.
  5. Burke ER. D-Ribose What You Need To Know. Garden City Park, NY: Avery Publishing Group 1999;1-43.
  6. Gross M, Reiter S, Zollner N. Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency. Klin Wochenschr 1989;67:1205-13. PubMed
  7. Teitelbaum JE, Johnson C, St Cyr J. The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. J Altern Complement Med 2006;12:857-62. PubMed
  8. Thompson J, Neutel J, Homer K, Tempero K, Shah A, Khankari R. Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects. J Clin Pharmacol 2014;54 PubMed

See these in context on the Ribose monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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