Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

DIM 150 Ingredients & Drug Interactions

by Woodstock Vitamins

DIM 150 label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking DIM 150 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

DIM 150 is a dietary supplement by Woodstock Vitamins with 2 active ingredients. Its ingredients are commonly taken for estrogen/hormone balance, acne and hormonal skin issues, prostate health support.Based on those ingredients, 269 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Diindolylmethane. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against DIM 150 by Woodstock Vitamins

Ask about any prescription or over-the-counter medication and we check it for interactions with DIM 150 by Woodstock Vitamins — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of DIM 150 by Woodstock Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

DIM 150 contains 2 active ingredients: diindolylmethane (the acronym DIM) and TrueBoc. Diindolylmethane is a compound derived from cruciferous vegetables like broccoli and cabbage.

The product also contains several inactive ingredients — hydroxypropyl methylcellulose, stearic acid, magnesium stearate, silica, and microcrystalline cellulose — which are fillers and binders that help form and stabilize the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Diindolylmethane's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: estrogen metabolism and detoxification support.
  • We looked for evidence on: Premenstrual syndrome (PMS), Mastalgia, Breast cancer, Prostate cancer, Benign prostatic hyperplasia (BPH), Cervical dysplasia — and 4 related terms.
  • The closest evidence on file: Diindolylmethane is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Diindolylmethane is rated "Insufficient Reliable Evidence To Rate" for Breast cancer, Colorectal cancer, Cervical dysplasia, Mastalgia, and more.

The effectiveness evidence for DIM 150 hasn't been established in the data we hold. Diindolylmethane has been studied for conditions including benign prostate enlargement, breast cancer, colorectal cancer, cervical dysplasia, and breast pain, but there is insufficient reliable evidence to rate how well it works for any of them.

We have no effectiveness data on file for TrueBoc.

The evidence, ingredient by ingredient Diindolylmethane

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Diindolylmethane is generally well tolerated in short-term studies, but long-term safety isn't well established. The most common side effects are diarrhea, gas, headache, nausea, rash, and vomiting.

A rare serious side effect called DRESS (drug rash with eosinophilia and systemic symptoms) has been reported. One case of stroke was reported in a patient taking diindolylmethane along with other supplements, though her increased stroke risk came from other medical conditions, making it unclear whether diindolylmethane played a role.

Because of possible effects on hormones and insufficient safety data, diindolylmethane is best avoided during pregnancy. There isn't enough safety information to use it while breastfeeding.

Side effects, ingredient by ingredient Diindolylmethane

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Diindolylmethane.
  • The most serious interaction on file is rated Moderate.
  • For scale: 269 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take DIM 150, check if you use any estrogen-containing medications like birth control pills or hormone replacement therapy — diindolylmethane may change how they work. Also flag any sodium-depleting water pills (diuretics) you take, and let your pharmacist know about any other medications you're on, since diindolylmethane may affect how certain drugs are broken down by your liver.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

DIM 150 is worth considering if you're interested in diindolylmethane and don't take estrogen-based medications, water pills, or drugs processed through CYP1A2. If you're on any prescription hormones, diuretics, or other medications, check them against our tool first.

Talk to your pharmacist or doctor before starting — especially if you're pregnant, breastfeeding, or have a history of stroke.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DIM 150, straight from the product label.

Brand Woodstock Vitamins
Barcode (UPC) 600300054149
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 310203
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DIM 150 by Woodstock Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
600300054149
IngredientAmount% DV
Diindolylmethane300 mg--
TrueBoc60 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Stearic Acid, Magnesium Stearate, Silica, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one to two capsules daily, or as directed by your healthcare practitioner.

Precautions

Consult your healthcare practitioner prior to use. Do not use if tamper seal is damaged.

Individuals taking medication or receiving cancer treatment should discuss potential interactions with their healthcare practitioner.

Storage: Keep tightly closed in a cool, dry place out of reach of children.

Professional use only

Formula

DIM 150 is an ideal combination of DIM (diindolylmethane) and truebroc (glucoraphanin) that helps protect estrogen-sensitive tissues by promoting healthy estrogen metabolism and supporting detoxification and neutralization of harmful estrogen metabolites and xenoestrogens.

truebroc Powerful antioxidant protection

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Storage: Keep tightly closed in a cool, dry place out of reach of children.

Formulation

Does not contain: Wheat, gluten, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

Estrogen metabolism and detoxification support formula

Manufactured in a GMP compliant facility.

Vegetarian caps

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

truebroc Powerful antioxidant protection Produced under US patent 5,725,895; 5,968,505; 5,968,567; 6,177,122; and 6,242,018 licensed from Brassica Protection Products LLC; truebroc is a trademark of Brassica Protection Products LLC.

General Statements

This package is completely recyclable

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

DIM 150 by Woodstock Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

DIM 150 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in DIM 150 by Woodstock Vitamins

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Diindolylmethane

Interacts with
269 drugs
300 mg per serving

Diindolylmethane (DIM) is a compound made when your body digests cruciferous vegetables, and it is sold as a supplement mainly for hormone balance and...

Diindolylmethane monograph & interactions

TrueBoc

60 mg per serving Form: Glucoraphanin

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Stearic Acid, Magnesium Stearate, Silica, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

DIM 150 by Woodstock Vitamins Drug Interactions

Want to check YOUR meds against DIM 150?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
269Drugs
116 Moderate 153 Minor

Ingredients driving the most interactions

Diindolylmethane 269

Individual Drug Interactions

The ingredients in DIM 150 interact with 269 drugs. Click any drug to see the details.

1 of the 2 ingredients in DIM 150 interact with drugs. Each result below shows which ingredient is responsible. Diindolylmethane

Each ingredient & the kinds of drugs it affects

For each ingredient in DIM 150 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Diindolylmethane3 drug types · 269 drugs

Diuretic Drugs

Theoretically, diindolylmethane might increase the risk of hyponatremia if used with sodium-depleting diuretics.
Large doses of diindolylmethane (600 mg daily) have been associated with two cases of asymptomatic hyponatremia in clinical research.

Likelihood Possible Evidence B
Estrogens

Theoretically, diindolylmethane might increase or decrease the effects of estrogens.
Diindolylmethane might have mild estrogenic or antiestrogenic effects. Theoretically, large amounts of diindolylmethane might interfere with hormone replacement therapy.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, diindolylmethane might lower serum levels of CYP1A2 substrates.
In vitro evidence suggests that diindolylmethane can induce CYP1A2. Theoretically, it might increase metabolism of CYP1A2 substrates and lower serum concentrations. This interaction has not been reported in humans.

Likelihood Unlikely Evidence D
Diindolylmethane full monograph & interactions
The maker

Brand information

Manufacturer and brand details for DIM 150, from the product label.

Woodstock Vitamins

See all Woodstock Vitamins products
Name
Village Vitality LLC
Street Address
79 Tinker Street Fl 2
City
Woodstock
State
NY
ZipCode
12498
Phone Number
(845) 521-7455
Web Address
www.WoodstockVitamins.com
Pharmacist Counseling Corner

DIM 150 by Woodstock Vitamins: Common Questions

Does DIM 150 by Woodstock Vitamins interact with any medications?
Yes. Based on its ingredients, DIM 150 has a known interaction with 269 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DIM 150 contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take DIM 150 if I'm pregnant or breastfeeding?
The data shows diindolylmethane is likely safe during pregnancy, so it's not off-limits — but because there's insufficient safety information for breastfeeding, it's best to avoid it while nursing. Talk with your doctor or pharmacist for personalized guidance based on your situation.
What side effects might I experience?
The most common ones are diarrhea, gas, headache, nausea, rash, and vomiting. A rare serious side effect called DRESS has been reported. Stop and contact your doctor if you develop a rash or other concerning symptoms.
Will DIM 150 help with breast cancer or prostate problems?
We don't have established evidence that it works for those conditions. Diindolylmethane has been studied for breast cancer, benign prostate enlargement, colorectal cancer, cervical dysplasia, and breast pain, but there's insufficient reliable evidence to rate its effectiveness for any of them.
How does diindolylmethane work?
Diindolylmethane is a compound found in cruciferous vegetables like broccoli and cabbage. It's theorized to have mild estrogenic or antiestrogenic properties, but the exact mechanisms aren't well established.
What is TrueBoc?
TrueBoc is the other active ingredient in this product, but we don't hold interaction or effectiveness data for it — your pharmacist may have additional information about this component.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DIM 150 label
Go deeper

The Full Monographs Behind DIM 150’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Diindolylmethane

Interacts with 269 drugs

Diindolylmethane (DIM) is a compound made when your body digests cruciferous vegetables, and it is sold as a supplement mainly for hormone balance and cancer prevention. Although early lab s...

Read the full Diindolylmethane monograph →
Sources

Sources & How We Checked

DIM 150's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Diindolylmethane 14 references
  1. Natl Inst Health, Natl Inst Environmental Health Sci. Indole-3-carbinol. Available at: http://ntp-server.niehs.nih.gov.
  2. Balk JL. Indole-3-carbinol for cancer prevention. Altern Med Alert 2000; 3:105-7.
  3. Riby JE, Chang GHF, Firestone GL, Bjeldanes LF. Ligand-independent activation of estrogen receptor function by 3,3'-diindolylmethane in human breast cancer cells. Biochem Pharmacol 2000;60:167-77. PubMed
  4. Lake BG, Tredger JM, Renwick AB, et al. 3'3-diindolylmethane induces CYP1A2 in cultured precision-cut human liver slices. Xenobiotica 1998;28:803-11. PubMed
  5. Dalessandri, K. M., Firestone, G. L., Fitch, M. D., Bradlow, H. L., and Bjeldanes, L. F. Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer. Nutr Canc PubMed
  6. Reed, G. A., Arneson, D. W., Putnam, W. C., Smith, H. J., Gray, J. C., Sullivan, D. K., Mayo, M. S., Crowell, J. A., and Hurwitz, A. Single-dose and multiple-dose administration of indole-3-carbinol to women: pharmacokinetics based on 3,3'-diindolylmetha
  7. Reed, G. A., Sunega, J. M., Sullivan, D. K., Gray, J. C., Mayo, M. S., Crowell, J. A., and Hurwitz, A. Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3'-diindolylmethane in healthy subjects. Cancer Epidemiol.Biomarkers Prev. 2008; PubMed
  8. Del Priore G., Gudipudi, D. K., Montemarano, N., Restivo, A. M., Malanowska-Stega, J., and Arslan, A. A. Oral diindolylmethane (DIM): pilot evaluation of a nonsurgical treatment for cervical dysplasia. Gynecol.Oncol. 2010;116(3):464-467. PubMed
  9. Heath, E. I., Heilbrun, L. K., Li, J., Vaishampayan, U., Harper, F., Pemberton, P., and Sarkar, F. H. A phase I dose-escalation study of oral BR-DIM (BioResponse 3,3'- Diindolylmethane) in castrate-resistant, non-metastatic prostate cancer. Am.J.Transl.R
  10. Jellinck, P. H., Forkert, P. G., Riddick, D. S., Okey, A. B., Michnovicz, J. J., and Bradlow, H. L. Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation. Biochem.Pharmacol. 3-9-1993;45(5):1129-1136. PubMed
  11. Bui PV, Moualla M, Upson DJ. A Possible Association of Diindolylmethane with Pulmonary Embolism and Deep Venous Thrombosis. Case Rep Med. 2016;2016:7527098. PubMed
  12. Castañon A, Tristram A, Mesher D, Powell N, Beer H, Ashman S, Rieck G, Fielder H, Fiander A, Sasieni P. Effect of diindolylmethane supplementation on low-grade cervical cytological abnormalities: double-blind, randomised, controlled trial. Br J Cancer. 20 PubMed
  13. Le TM, Sanders CJ, van de Corput L, van Erpecum KJ, Röckmann H. Drug rash with eosinophilia and systemic symptoms caused by the dietary supplement diindolylmethane. J Allergy Clin Immunol Pract. 2016 Jan-Feb;4(1):175-6. PubMed
  14. Pence ST, Mehta K, Crum-Bailey J. The Serious Side of Supplements: An Ischemic Stroke in a Healthy 38-year-old Female. Mil Med 2022. PubMed

See these in context on the Diindolylmethane monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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