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Dietary supplement

Dissolvable B12 6000 mcg Cherry Flavored Ingredients & Drug Interactions

by Sundown

Dissolvable B12 6000 mcg Cherry Flavored label
See full label image
Lozenge Category: Vitamin
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Dissolvable B12 6000 mcg Cherry Flavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Dissolvable B12 6000 mcg Cherry Flavored is a dietary supplement by Sundown with 2 active ingredients. Its ingredients are commonly taken for treating or preventing b12 deficiency, pernicious anemia, low energy and fatigue.Based on those ingredients, 20 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Vitamin B12. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Dissolvable B12 6000 mcg Cherry Flavored by Sundown

Ask about any prescription or over-the-counter medication and we check it for interactions with Dissolvable B12 6000 mcg Cherry Flavored by Sundown — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Dissolvable B12 6000 mcg Cherry Flavored by Sundown

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients, both forms of vitamin B12: Vitamin B12 itself and Coenzyme B12 (also called cyanocobalamin and methylcobalamin, depending on the form). Together they deliver 6000 micrograms of B12 in a dissolvable cherry-flavored lozenge.

The other ingredients are inactive — mannitol (a sweetener), crospovidone (a binder), beet juice color, stearic acid, and natural cherry flavor. There are no fillers in the sense of meaningless bulk; everything here serves a purpose in the tablet's structure or taste.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: B vitamins aid in food-to-energy conversion.
  • We looked for evidence on: Fatigue, Vitamin B12 deficiency, Energy metabolism, Physical performance.
  • The strongest evidence on file: Vitamin B12 is rated "Effective" for Vitamin B12 deficiency (Natural Medicines).
  • Also on file: Vitamin B12 is rated "Possibly Ineffective" for Physical performance.
  • Also on file: Vitamin B12 is rated "Insufficient Reliable Evidence To Rate" for Fatigue.

Vitamin B12 is effective for treating B12 deficiency and a rare genetic condition called Imerslund-Grasbeck disease. The data also shows it's likely effective for cyanide poisoning — though that's an emergency setting, not something you'd use this lozenge for.

It's possibly effective for canker sores and a nerve pain condition called postherpetic neuralgia, but the evidence there is less established.

The evidence, ingredient by ingredient Vitamin B12

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

B12 is generally well-tolerated when taken by mouth. Your body excretes excess B12 in the urine, so there's no established upper limit — you can't overdose.

Allergic reactions are rare but possible; they may show up as rash, itching, redness, or hives. In extremely rare cases linked to correction of a severe type of anemia (megaloblastic anemia), B12 has been associated with a dangerous drop in potassium (hypokalemia), but this is case-report data and occurs almost exclusively with intramuscular injection, not oral lozenges.

B12 is needed during pregnancy and breastfeeding and is considered safe at normal recommended amounts — follow your provider's guidance on dosing.

Side effects, ingredient by ingredient Vitamin B12

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin B12.
  • The most serious interaction on file is rated Minor.
  • For scale: 20 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take metformin (Glucophage) for diabetes, mention this supplement to your pharmacist — there's a minor interaction, but it may actually help offset the drug's effect on your B12 levels. No other medications have documented interactions with the B12 in our data, but check your exact medications with the tool on this page to be thorough.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This is a solid choice if you're deficient in B12 or taking metformin and want to protect your levels. The lozenge form is convenient and well-tolerated.

If you have a history of cobalt allergy or are on other medications, check them below before you start. Talk to your pharmacist if you're pregnant, breastfeeding, or taking multiple supplements.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Dissolvable B12 6000 mcg Cherry Flavored, straight from the product label.

Brand Sundown
Barcode (UPC) 030768185657
Net contents 60 Microlozenge(s)
Market status On market
Date entered into DSLD Dec 22, 2019
DSLD ID 212352
Product type Vitamin
Supplement form Lozenge
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Dissolvable B12 6000 mcg Cherry Flavored by Sundown, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Microlozenge(s)
Maximum serving Sizes:
1 Microlozenge(s)
UPC/BARCODE
030768185657
IngredientAmount% DV
Vitamin B126000 mcg250000%
Coenzyme B12100 mcg--

Other ingredients: Mannitol, Crospovidone, Beet juice color, Stearic Acid, natural Cherry flavor, Contains < 2% of

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Clean Nutrition Sundown believes in clean nutrition and being transparent. That's why you won't find genetically modified ingredients, gluten, wheat, dairy, lactose, or artificial flavors in any of our products. Non-GMO No gluten No wheat No milk No lactose No artificial flavor No preservatives No sugar No soy No starch No yeast No peanuts No tree nuts No fish Sodium free

B Vitamins aid in the conversion of food into energy

Gluten free Dairy free Non-GMO

For energy support & nervous system health

Vegetarian

Precautions

Keep out of reach of children.

Tamper resistant: Do not use if seal under cap is broken or missing.

As a reminder, discuss the supplements and medications you take with your health care providers. Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Storage

Store at room temperature and avoid excessive heat.

General Statements

US only Discard seal & empty before recycling Check locally Plastic bottle Not recycled in all communities how2recycle.info

Clean nutrition

FDA Statement of Identity

Vitamin Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take one (1) microlozenge daily, preferably with a meal. Place microlozenge under tongue until fully dissolved and then swallow.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

2019 Rexall Sundown

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Dissolvable B12 6000 mcg Cherry Flavored by Sundown label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Dissolvable B12 6000 mcg Cherry Flavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Dissolvable B12 6000 mcg Cherry Flavored by Sundown

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Microlozenge(s) Dosage formLozenge Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B12

Interacts with
20 drugs
6000 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Coenzyme B12

Interacts with
20 drugs
100 mcg per serving Form: Dibencozide

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Coenzyme B12 monograph & interactions

Other (inactive) ingredients: Mannitol, Crospovidone, Beet juice color, Stearic Acid, Natural Cherry flavor, Contains < 2% of. These complete the product’s ingredient list but are not active constituents.

Interaction report

Dissolvable B12 6000 mcg Cherry Flavored by Sundown Drug Interactions

Want to check YOUR meds against Dissolvable B12 6000 mcg Cherry Flavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
20Drugs
20 Minor

Ingredients driving the most interactions

Vitamin B12 20

Individual Drug Interactions

The ingredients in Dissolvable B12 6000 mcg Cherry Flavored interact with 20 drugs. Click any drug to see the details.

1 of the 2 ingredients in Dissolvable B12 6000 mcg Cherry Flavored interact with drugs. Each result below shows which ingredient is responsible. Vitamin B12

Each ingredient & the kinds of drugs it affects

For each ingredient in Dissolvable B12 6000 mcg Cherry Flavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Dissolvable B12 6000 mcg Cherry Flavored, from the product label.

Sundown

See all Sundown products
Name
Rexall Sundown, Inc.
City
Boca Raton
State
FL
ZipCode
33487
Phone Number
1-888-848-2435
Pharmacist Counseling Corner

Dissolvable B12 6000 mcg Cherry Flavored by Sundown: Common Questions

Does Dissolvable B12 6000 mcg Cherry Flavored by Sundown interact with any medications?
Yes. Based on its ingredients, Dissolvable B12 6000 mcg Cherry Flavored has a known interaction with 20 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Dissolvable B12 6000 mcg Cherry Flavored contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work for vitamin B12 deficiency?
Yes, vitamin B12 is effective for treating B12 deficiency. This 6000 mcg lozenge is a high-dose form, so it's well-suited to building your levels back up — but how long that takes depends on your baseline and how much you absorb. Your doctor or pharmacist can tell you what to expect.
Is it safe to take while pregnant or breastfeeding?
Yes. B12 is actually needed during pregnancy and breastfeeding and is considered safe at normal recommended amounts. Follow your provider's specific dosing advice based on your individual needs.
What are the side effects?
B12 is very well-tolerated when taken by mouth. Allergic reactions (rash, itching, redness, hives) are rare. The most common side effects from B12 injections are soreness at the injection site — not relevant here since this is a lozenge. Serious effects are extremely rare and almost always tied to intramuscular injection, not oral tablets.
Can I take this with metformin?
Yes, and it may actually help. Metformin can lower B12 levels over time by reducing how much your body absorbs. This supplement may offset that effect, though timing and dose matter — ask your pharmacist for the best approach for you.
Do these lozenges have any fillers or unnecessary ingredients?
No. The inactive ingredients — mannitol, crospovidone, beet juice color, stearic acid, and natural cherry flavor — all serve a function in making the tablet dissolve smoothly and taste good. Nothing unnecessary is in there.
Can I take too much B12?
No. B12 has no established upper limit because your body excretes excess in the urine. You can't overdose on it, which is one reason high-dose lozenges like this one are considered very safe.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Dissolvable B12 6000 mcg Cherry Flavored is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Dissolvable B12 6000 mcg Cherry Flavored label
Go deeper

The Full Monographs Behind Dissolvable B12 6000 mcg Cherry Flavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph →
Sources

Sources & How We Checked

Dissolvable B12 6000 mcg Cherry Flavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B12 30 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  2. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
  3. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  4. Lange H, Suryapranata H, De Luca G, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med 2004;350:2673-81. PubMed
  5. Collin, S. M., Metcalfe, C., Refsum, H., Lewis, S. J., Zuccolo, L., Smith, G. D., Chen, L., Harris, R., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Ebbing, M., Bonaa, K. H., Nygard, O., Ueland, P. M., Grau, M. V., Baron, J. A., Donovan, J. L., Nea
  6. Geissbuhler, P., Mermillod, B., and Rapin, C. H. Elevated serum vitamin B12 levels associated with CRP as a predictive factor of mortality in palliative care cancer patients: a prospective study over five years. J.Pain Symptom.Manage. 2000;20(2):93-103. PubMed
  7. Salles, N., Herrmann, F., Sakbani, K., Rapin, C. H., and Sieber, C. High vitamin B12 level: a strong predictor of mortality in elderly inpatients. J Am Geriatr.Soc 2005;53(5):917-918.
  8. Looker, H. C., Fagot-Campagna, A., Gunter, E. W., Pfeiffer, C. M., Sievers, M. L., Bennett, P. H., Nelson, R. G., Hanson, R. L., and Knowler, W. C. Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res R
  9. Uhl, W., Nolting, A., Golor, G., Rost, K. L., and Kovar, A. Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study. Clin Toxicol (Phila) 2006;44 Suppl 1:17-28. PubMed
  10. Borron, S. W., Baud, F. J., Barriot, P., Imbert, M., and Bismuth, C. Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation. Ann Emerg.Med 2007;49(6):794-801, 801. PubMed
  11. Borron, S. W., Baud, F. J., Megarbane, B., and Bismuth, C. Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation. Am J Emerg.Med 2007;25(5):551-558. PubMed
  12. Lewis, J. G. Gout, Steatorrhoea, and Megaloblastic Anaemia. Ann Rheum.Dis 1962;21(3):284-286. PubMed
  13. Tal, S., Shavit, Y., Stern, F., and Malnick, S. Association between vitamin B12 levels and mortality in hospitalized older adults. J Am Geriatr.Soc 2010;58(3):523-526. PubMed
  14. Baztan, J. J., Gavidia, J. J., Gomez-Pavon, J., Esteve, A., and Ruiperez, I. High vitamin B12 levels and in-hospital mortality. J Am Geriatr.Soc 2010;58(11):2237-2238. PubMed
  15. Omboni, E., Checchini, M., and Longoni, F. [Hypopotassemia and megaloblastic anemia. Presentation of a case]. Minerva Med 8-31-1987;78(16):1255-1257.
  16. Aalfs As, Scholvinck LH, Horvath B. Acneiform eruption in a 5-year old due to vitamin B12 supplementation. Eur J Dermatol 2013;23(5):726-7. PubMed
  17. Balta I, Ozuguz P. Vitamin B12-induced acneiform eruption. Cutan Ocul Toxicol 2014;33(2):94-5. PubMed
  18. Carman KB, Belgemen T, Yis U. Involuntary movements misdiagnosed as seizure during vitamin B12 treatment. Pediatr Emerg Care 2013;29(11):1223-4. PubMed
  19. Djuric V, Bogic M, Popadic AP, et al. Anaphylactic reaction to hydroxycobalamin with tolerance to cyanocobalamin. Ann Allergy Asthma Immunol 2012;108(3):207-8. PubMed
  20. Kartel O, Gulec M, Demirel F, et al. Vitamin B12 allergy and successful desensitization with cyanocobalamin: A case report. Allergol Immunopath (Madr) 2012;40(5):324-5.
  21. Patiroglu T, Unal E, Yildirim S. Infantile tremor syndrome associated with cobalamin therapy: A case report. Clin Neurol Neurosurg 2013;115(9):1903-5. PubMed
  22. Schulte S, Barkema LW, Kardaun SH. Long-lasting atypical acneiform eruption with prominent comedones induced by hydroxocobalamin (vitamin B12). J Dtsch Dermatol Ges 2014;12(6):502-3.
  23. Zanus C, Alberini E, Costa P, et al. Involuntary movements after correction of vitamin B12 deficiency: A video-case report. Epileptic Disord 2012;14(2):174-80. PubMed
  24. Fanidi A, Carreras-Torres R, Larose TL, et al. Is high vitamin B12 status a cause of lung cancer? Int J Cancer. 2019 Sep 15;145(6):1499-1503. PubMed
  25. Fujita Y, Mizukami T, Maya Y, et al. Vitamin B12 allergy manifesting as lymphomatoid contact dermatitis. Eur J Dermatol. 2020;30(3):304-305. PubMed
  26. Dépret F, Hoffmann C, Daoud L, et al. Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study. Crit Care. 2019;23(1):421. PubMed
  27. Khairan P, Sobue T, Eshak ES, et al. Association of dietary intakes of vitamin B12, vitamin B6, folate, and methionine with the risk of esophageal cancer: the Japan Public Health Center-based (JPHC) prospective study. BMC Cancer 2021;21(1):982. PubMed
  28. Evans J, Pandya A, Ding Y, Qunibi WY. Hydroxocobalamin-Induced Oxalate Nephropathy in a Patient With Smoke Inhalation. Kidney Int Rep 2021;6(8):2228-2231. PubMed
  29. Lacombe V, Chabrun F, Lacout C, et al. Persistent elevation of plasma vitamin B12 is strongly associated with solid cancer. Sci Rep 2021;11(1):13361. PubMed
  30. Pegalajar-García MD, Cebolla-Verdugo M, Prados-Carmona Á, Llamas-Segura C, Navarro-Triviño FJ. Systemic allergic dermatitis to cobalt present in cyanocobalamin supplementation. Contact Dermatitis 2023;89(3):203-205. PubMed

See these in context on the Vitamin B12 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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