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Dietary supplement

DMAE Bitartrate 350 mg Unflavored Ingredients & Drug Interactions

by Nutricost

Powder Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

DMAE Bitartrate 350 mg Unflavored is a dietary supplement by Nutricost with 1 active ingredient. Its ingredients are commonly taken for memory and focus, mood and mental clarity, adhd-type symptoms.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are DMAE Bitartrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of DMAE Bitartrate 350 mg Unflavored by Nutricost

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: DMAE bitartrate, 350 mg per serving. DMAE (dimethylaminoethanol) is a compound that research suggests may influence acetylcholine, a neurotransmitter involved in brain function and muscle control.

The product itself is unflavored powder with no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Deanol product and its label doesn't state a use — see Deanol's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for DMAE is thin. For Alzheimer disease and tardive dyskinesia (involuntary movement disorders), the research suggests it's likely ineffective.

For aging skin, ADHD, and athletic performance, we don't have enough reliable evidence to say whether it works or not. If you're considering it for one of these purposes, there's no solid data backing its use.

The evidence, ingredient by ingredient Deanol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

DMAE is generally well tolerated by some adults, but side effects do occur. The most common ones reported are abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting.

Less commonly, people have reported headache, insomnia, confusion, or mood changes including depression. At doses above 1000 mg daily, mood disturbances become more likely; at 1500 mg daily, it's been reported to worsen schizophrenia symptoms in people with that condition.

For pregnancy, there isn't enough safety data to know either way—talk with your doctor or pharmacist for personalized advice. For breastfeeding, the safety data advises against it, so avoid use.

Side effects, ingredient by ingredient Deanol

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Deanol.
  • The most serious interaction on file is rated Minor.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on any anticholinergic drugs (such as antihistamines, some antidepressants, or medications for overactive bladder or muscle spasms) or cholinergic drugs (such as myasthenia gravis or Alzheimer disease medications). Even though the interactions are Minor, DMAE may theoretically reduce the effect of anticholinergics or boost the effects and side effects of cholinergics.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

DMAE has limited evidence behind it for any condition and may cause digestive upset or mood changes in some people. If you take anticholinergic or cholinergic medications, check your specific drugs with your pharmacist before starting.

Pregnant or breastfeeding? Discuss it with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DMAE Bitartrate 350 mg Unflavored, straight from the product label.

Brand Nutricost
Barcode (UPC) 702669931076
Net contents 100 Gram(s); 0.22 lbs
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 269431
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DMAE Bitartrate 350 mg Unflavored by Nutricost, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Scoop(s)
Maximum serving Sizes:
1 Scoop(s)
Servings per container
286
UPC/BARCODE
702669931076
IngredientAmount% DV
DMAE Bitartrate350 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

(Please read the entire label before use)

Warning: This product is only intended to be consumed by healthy individuals 18 years of age or older.

Consult your physician prior to use if you are pregnant or nursing. Consult your physician prior to use if you are taking any medications or have any medical condition.

Keep out of reach of children.

Do not exceed recommended use. Improper use will not improve results. Discontinue use and seek professional assistance immediately if you experience unwanted side effects. Discontinue use 2 weeks prior to surgery. Do not use if safety seal is broken or missing.

Suggested/Recommended/Usage/Directions

Recommended Use: As a dietary supplement, consume 1 scoop one to three times daily as needed with 8 ounces of cold water or juice.

Storage

Store in a cool, dry place.

General Statements

Contents are sold by weight, not volume. Some settling may occur.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

350 mg per serving

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Quality Guaranteed Nuricost Made in the USA

Formulation

Gluten free product Non GMO

See for yourself

DMAE Bitartrate 350 mg Unflavored by Nutricost label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in DMAE Bitartrate 350 mg Unflavored by Nutricost

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Scoop(s) Dosage formPowder Servings per container286 Amounts shown are per serving.

DMAE Bitartrate

Interacts with
219 drugs
350 mg per serving

Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limite...

DMAE Bitartrate monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

DMAE Bitartrate 350 mg Unflavored by Nutricost Drug Interactions

Want to check YOUR meds against DMAE Bitartrate 350 mg Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
219Drugs
219 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in DMAE Bitartrate 350 mg Unflavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

DMAE Bitartrate2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
Cholinergic Drugs

Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for DMAE Bitartrate 350 mg Unflavored, from the product label.

Nutricost

See all Nutricost products
Name
Nutricost
Street Address
7 S 1550 W #200
City
Lindon
State
UT
ZipCode
84042
Phone Number
(866) 438-3694
Web Address
www.nutricost.com
Pharmacist Counseling Corner

DMAE Bitartrate 350 mg Unflavored by Nutricost: Common Questions

Does DMAE Bitartrate 350 mg Unflavored by Nutricost interact with any medications?
Yes. Based on its ingredients, DMAE Bitartrate 350 mg Unflavored has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DMAE Bitartrate 350 mg Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is DMAE and what is it supposed to do?
DMAE (dimethylaminoethanol) is a compound thought to influence acetylcholine, a chemical messenger in the brain and muscles. It's been studied for brain health, skin aging, and ADHD, but the evidence is limited or shows it's likely ineffective for most uses.
What are the most common side effects?
The most common ones are abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting. Other reported effects include headache, insomnia, and in some people, mood changes.
Is it safe to take if I have a psychiatric condition?
At higher doses (1000 mg or more daily), DMAE has been reported to cause mood changes, and at 1500 mg daily it's been linked to worsening schizophrenia symptoms. If you have a psychiatric condition, talk with your doctor or pharmacist before taking it.
Can I take this while pregnant or breastfeeding?
For pregnancy, there isn't enough safety data to know either way—discuss it with your doctor or pharmacist. For breastfeeding, the safety data advises against it, so avoid use.
Does DMAE really work for Alzheimer disease or ADHD?
For Alzheimer disease, research suggests it's likely ineffective. For ADHD, we don't have enough reliable evidence to say whether it works. The evidence for DMAE overall is quite limited.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DMAE Bitartrate 350 mg Unflavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DMAE Bitartrate 350 mg Unflavored label
Go deeper

The Full Monographs Behind DMAE Bitartrate 350 mg Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

DMAE Bitartrate 350 mg Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Deanol 15 references
  1. Davies C, Maidment S, Hanley P, et al. Dimethylaminoethanol (DMAE). HSE. Risk assessment document; EH72/2;1997. (TOXLINE).
  2. Re O. 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp 1974;16:1238-42.
  3. Pieralisi G, Ripari P, Vecchiet L. Effects of a standardized ginseng extract combined with dimethylaminoethanol bitartrate, vitamins, minerals, and trace elements on physical performance during exercise. Clin Ther 1991;13:373-82.
  4. George J, Pridmore S, Aldous D. Double blind controlled trial of deanol in tardive dyskinesia. Aust N Z J Psychiatry 1981;15:68-71. PubMed
  5. Penovich P, Morgan JP, Kerzner B, et al. Double-blind evaluation of deanol in tardive dyskinesia. JAMA 1978;239:1997-8. DOI
  6. de Montigny C, Chouinard G, Annable L. Ineffectiveness of deanol in tardive dyskinesia: a placebo controlled study. Psychopharmacology (Berl) 1979;65:219-23. PubMed
  7. Lindeboom SF, Lakke JP. Deanol and physostigmine in the treatment of L-dopa-induced dyskinesias. Acta Neurol Scand 1978;58:134-8. PubMed
  8. Jus A, Villeneuve A, Gautier J, et al. Deanol, lithium and placebo in the treatment of tardive dyskinesia. A double-blind crossover study. Neuropsychobiology 1978;4:140-9. PubMed
  9. Lewis JA, Young R. Deanol and methylphenidate in minimal brain dysfunction. Clin Pharmacol Ther 1975;17:534-40. PubMed
  10. Fisman M, Mersky H, Helmes E. Double-blind trial of 2-dimethylaminoethanol in Alzheimer's disease. Am J Psychiatry 1981;138:970-2. PubMed
  11. Ferris SH, Sathananthan G, Gershon S, et al. Senile dementia: treatment with deanol. J Am Geriatr Soc 1977;25:241-4. PubMed
  12. Haug BA, Holzgraefe M. Orofacial and respiratory tardive dyskinesia: potential side effects of 2-dimethylaminoethanol (deanol)? Eur Neurol 1991;31:423-5. PubMed
  13. Casey DE. Mood alterations during deanol therapy. Psychopharmacology (Berl) 1979;62:187-91. PubMed
  14. Sergio W. Use of DMAE (2-dimethylaminoethanol) in the induction of lucid dreams. Med Hypotheses 1988;26:255-7. PubMed
  15. Osol A, Hoover JE, eds. Remington's Pharmaceutical Science, 15th ed. Easton, PA: Mack Publishing Company, 1975.

See these in context on the Deanol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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