Dr. Cutler's Ultimate Memory Formula Ingredients & Drug Interactions
by True Health
What is this page for?
First and foremost: checking Dr. Cutler's Ultimate Memory Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Dr. Cutler's Ultimate Memory Formula is a dietary supplement by True Health with 2 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis, correcting vitamin d deficiency, immune system support.Based on those ingredients, 854 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D3, Sharp-PS(R) Gold. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Dr. Cutler's Ultimate Memory Formula by True Health
Ask about any prescription or over-the-counter medication and we check it for interactions with Dr. Cutler's Ultimate Memory Formula by True Health — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Dr. Cutler's Ultimate Memory Formula by True Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This formula has three active ingredients. Docosahexaenoic acid is an omega-3 fatty acid from fish oil.
Vitamin D3 supports bone health and calcium absorption. Phosphatidylserine is a phospholipid — a fat-like substance found in cell membranes — thought to support brain function.
The capsule also contains gelatin, microcrystalline cellulose, and magnesium stearate as inactive ingredients.
Does it work?
Moderate evidence
Evidence for this formula's ingredients is mixed. Vitamin D3 is effective for rickets, osteomalacia (soft bones), renal bone disease, and certain calcium-regulation disorders.
Phosphatidylserine is possibly effective for age-related cognitive decline and Alzheimer's disease, but evidence is insufficient to rate it for general cognitive function, ADHD, or athletic performance. We hold no effectiveness data for docosahexaenoic acid in our system.
How safe is it?
Well-documented data
Vitamin D3 is generally well tolerated at recommended doses, though very high doses over time can cause toxicity with symptoms including high blood calcium (hypercalcemia), weak bones, vision problems, and — in children — slowed growth. It's often used in pregnancy at recommended amounts under a doctor's guidance, and is considered acceptable while breastfeeding at recommended doses.
Phosphatidylserine is generally well tolerated in studies, but long-term safety isn't fully established. Common side effects include gas, stomach upset, headache, trouble sleeping (especially at higher doses), and nausea.
There isn't enough safety information for phosphatidylserine in pregnancy or breastfeeding, so those are best avoided.
Meds to double-check
Moderate interaction found
Before taking this formula, check with your doctor or pharmacist if you take water pills (thiazide diuretics), medications for abnormal heart rhythm like digoxin, diltiazem, or verapamil, atorvastatin or other statins, psoriasis treatments like calcipotriene, anticholinergic drugs (which dry mouth or slow digestion), or cholinergic drugs (which work on nerve signals). Vitamin D3 at high doses poses the biggest concerns.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This formula may be worth considering if you're interested in brain health and bone support, but it's not right for everyone. If you take water pills, heart medications, statins, psoriasis treatments, or drugs that affect nerve signals, talk with your doctor or pharmacist before starting — some of these combinations need monitoring.
Pregnant or breastfeeding people should check with their own healthcare provider first, especially about phosphatidylserine.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Dr. Cutler's Ultimate Memory Formula, straight from the product label.
| Brand | True Health |
|---|---|
| Net contents | 30 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Dec 21, 2012 |
| DSLD ID | 16777 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Dr. Cutler's Ultimate Memory Formula by True Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Docosahexaenoic Acid | 8 mg | -- |
| Vitamin D3 | 2000 IU | 500% |
| Phosphatidylserine | 100 mg | -- |
| Sharp-PS(R) Gold | 223 mg | -- |
Other ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Caution: If you are under a physician's care or taking medication, or if you are pregnant or nursing, consult your healthcare professional before using this product.
KEEP OUT OF REACH OF CHILDREN.
Storage
STORE IN A COOL, DRY PLACE.
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
For a Sharp Mind!*
Contains the World's Finest Ingredients.
This product is manufactured in a NSF GMP registered facility.
Seals/Symbols
SCIENTIFICALLY FORMULATED DOCTOR APPROVED
Sharp-PS(R) GOLD
MADE IN U.S.A.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: Take one to three capsules daily or as directed by your healthcare professional.
General
300-TUMFC-A
Brand IP Statement(s)
Sharp-PS(R) is a registered trademark of Enzymotec, Ltd.
Formula
Contains fish species of sprat and blue whiting.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Dr. Cutler's Ultimate Memory Formula by True Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Dr. Cutler's Ultimate Memory Formula by True Health
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Vitamin D3
Interacts with715 drugs
Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...
Vitamin D3 monograph & interactionsSharp-PS(R) Gold
Interacts with219 drugs
Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...
Sharp-PS(R) Gold monograph & interactions- › Docosahexaenoic Acid
- › Phosphatidylserine
Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Dr. Cutler's Ultimate Memory Formula by True Health Drug Interactions
HelloPharmacist Interaction Report
Dr.
Cutler's Ultimate Memory Formula by True Health contains vitamin D3 and phosphatidylserine, both of which interact with medications. The most serious concerns involve vitamin D3 and thiazide diuretics (water pills), which together can raise calcium levels in your blood to unsafe amounts — a condition called hypercalcemia.
Altogether, these interactions span 855 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Vitamin D3 has moderate interactions with several heart and cholesterol drugs. It can reduce how well verapamil, diltiazem, and digoxin work for abnormal heart rhythms.
It may also lower atorvastatin (a statin) levels by up to 55% in some studies, though researchers haven't confirmed this changes cholesterol control in real patients. It can also increase the risk of high calcium with calcipotriene, a psoriasis treatment.
Additionally, very high doses of vitamin D3 may theoretically speed up how your body breaks down certain medications processed through CYP3A4 enzymes — a minor concern.
Phosphatidylserine has moderate interactions with anticholinergic drugs (which dry out secretions and slow digestion) and cholinergic drugs (which work on nerve signals). Theoretically, phosphatidylserine could reduce anticholinergic effects or add to cholinergic effects.
We couldn't check docosahexaenoic acid — we hold no interaction data for it. Before you start this formula, run your exact medications through the interaction checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Dr. Cutler's Ultimate Memory Formula?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Dr. Cutler's Ultimate Memory Formula interact with 854 drugs. Click any drug to see the details.
2 of the 2 ingredients in Dr. Cutler's Ultimate Memory Formula interact with drugs. Each result below shows which ingredient is responsible. Vitamin D3 Sharp-PS(R) Gold
AcepromazineAtravet
How Acepromazine interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acepromazine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Caffeine, Pyrilamine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Phenylephrine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, Doxylamine, PseudoephedrineEx Strength Tylenol Sinus Nighttime
How Acetaminophen, Doxylamine, Pseudoephedrine interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Doxylamine, Pseudoephedrine interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Dr. Cutler's Ultimate Memory Formula — through 2 ingredients. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetaminophen, Phenylephrine, Chlorpheniramine interactionVitamin D3Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D3 + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetylcholineMiochol-E
How Acetylcholine interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps(r) GoldCholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Read the full Sharp-ps(r) Gold + Acetylcholine interactionAclidinium BromideTudorza Pressair
How Aclidinium Bromide interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Aclidinium Bromide interactionAclidinium Bromide, Formoterol Fumarate DihydrateDuaklir Pressair
How Aclidinium Bromide, Formoterol Fumarate Dihydrate interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Aclidinium Bromide, Formoterol Fumarate Dihydrate interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Sharp-ps(r) GoldAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Read the full Sharp-ps(r) Gold + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAlginic Acid, Aluminum HydroxideRafton
How Alginic Acid, Aluminum Hydroxide interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D3Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D3 + Alginic Acid, Aluminum Hydroxide interactionAluminum Acetate, Benzethonium ChlorideBuro-Sol Otic Solution
How Aluminum Acetate, Benzethonium Chloride interacts with Dr. Cutler's Ultimate Memory Formula — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D3Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D3 + Aluminum Acetate, Benzethonium Chloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Dr. Cutler's Ultimate Memory Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin D3
Aluminum
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.
Atorvastatin (Lipitor)
Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.
Calcipotriene (Dovonex)
Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.
Digoxin (Lanoxin)
Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.
Diltiazem (Cardizem, Others)
Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.
Thiazide Diuretics
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.
Verapamil (Calan, Others)
Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.
Sharp-PS(R) Gold
Anticholinergic Drugs
Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.
Cholinergic Drugs
Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.
Brand information
Manufacturer and brand details for Dr. Cutler's Ultimate Memory Formula, from the product label.
True Health
See all True Health products- Name
- True Health(TM)
- Street Address
- P.O. Box 3703
- City
- Hueytown
- State
- AL
- ZipCode
- 35023
- Phone Number
- 1-800-746-4513
- Web Address
- www.TrueHealth.com
Dr. Cutler's Ultimate Memory Formula by True Health: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Dr. Cutler's Ultimate Memory Formula’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Vitamin D
Interacts with 715 drugsVitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...
Read the full Vitamin D monograph → Herb & supplement monographPhosphatidylserine
Interacts with 219 drugsPhosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinking. Some research suggests possible bene...
Read the full Phosphatidylserine monograph →Sources & How We Checked
Dr. Cutler's Ultimate Memory Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 35 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Vitamin D 26 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Tatro DS, ed. Drug Interactions Facts. Facts and Comparisons Inc., St. Louis, MO. 1999.
- Koutkia P, Chen TC, Holick MF. Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med 2001;345:66-7. PubMed
- Bar-Or D, Yoel G. Calcium and calciferol antagonize effect of verapamil in atrial fibrillation. Br Med J 1981;282:1585-6.
- Demontis R, Leflon A, Fournier A, et al. 1 alpha(OH) vitamin D3 increases plasma aluminum in hemodialyzed patients taking AI(OH)3. Clin Nephrol 1986;26:146-9.
- Crowe M, Wollner L, Griffiths RA. Hypercalcemia following vitamin D and thiazide therapy in the elderly. Practitioner 1984;228:312-3.
- Parfitt AM. Thiazide-induced hypercalcemia in vitamin D-treated hypoparathyroidism. Ann Intern Med 1972;77:557-63. PubMed
- Thiazide diuretics and the risk of osteoporosis. Pharmacist's Letter/Prescriber's Letter 2003;19(11):191105.
- Moon J. The role of vitamin D in toxic metal absorption. J Am Coll Nutr 1994;13:559-64.
- Demontis R, Reissi D, Noel C, et al. Indirect clinical evidence that 1alphaOH vitamin D<SUB>3</SUB> increases the intestinal absorption of aluminum. Clin Nephrol 1989;31:123-7.
- Adler AJ, Berlyne GM. Duodenal aluminum absorption in the rat: effect of vitamin D. Am J Physiol 1985;249:G209-13. PubMed
- Schwartz JB. Effects of vitamin D supplementation in atorvastatin-treated patients: A new drug interaction with an unexpected consequence. Clin Pharmacol Ther 2009;85:198-203. PubMed
- Dietary reference intakes for calcium and vitamin D. Institute of Medicine, November 30, 2010. Available at: http://www.iom.edu/~/media/Files/Report%20Files/2010/Dietary-Reference-Intakes-for-Calcium-and-Vitamin-D/Vitamin%20D%20and%20Calcium%202010%20Repo
- Cox KA, Dunn MA. Aluminum toxicity alters the regulation of calbindin-D28k protein and mRNA expression in chick intestine. J Nutr 2001;131:2007-13. PubMed
- Escribano, J., Balaguer, A., Pagone, F., Feliu, A., and Roque, I. Figuls. Pharmacological interventions for preventing complications in idiopathic hypercalciuria. Cochrane.Database.Syst.Rev. 2009;(1):CD004754. PubMed
- Carlton, S., Clopton, D., and Cappuzzo, K. A. Vitamin D deficiency: appropriate replenishment therapies and the effects of vitamin D toxicity. Consult Pharm 2010;25(3):171-177. PubMed
- Wang, H., Xia, N., Yang, Y., and Peng, D. Q. Influence of vitamin D supplementation on plasma lipid profiles: a meta-analysis of randomized controlled trials. Lipids Health Dis. 2012;11:42. PubMed
- Turner AN, Carr Reese P, Fields KS, Anderson J, Ervin M, Davis JA, Fichorova RN, Roberts MW, Klebanoff MA, Jackson RD. A blinded, randomized controlled trial of high-dose vitamin D supplementation to reduce recurrence of bacterial vaginosis. Am J Obstet G PubMed
- Weiner M, Epstein FH. Signs and symptoms of electrolyte disorders. Yale J Biol Med. 1970;43(2):76-109.
- Lappe J, Watson P, Travers-Gustafson D, Recker R, Garland C, Gorham E, Baggerly K, McDonnell SL. Effect of Vitamin D and Calcium Supplementation on Cancer Incidence in Older Women: A Randomized Clinical Trial. JAMA. 2017 Mar 28;317(12):1234-1243. PubMed
- Roth DE, Leung M, Mesfin E, Qamar H, Watterworth J, Papp E. Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials. BMJ. 2017;359:j5237. PubMed
- Murai IH, Fernandes AL, Sales LP, et al. Effect of a single high dose of vitamin D3 on hospital length of stay in patients with moderate to severe COVID-19: A randomized clinical trial. JAMA. 2021.
- Wang Z, Schuetz EG, Xu Y, Thummel KE. Interplay between vitamin D and the drug metabolizing enzyme CYP3A4. J Steroid Biochem Mol Biol 2013;136:54-8. PubMed
- Doyle D, Browne U, Brickley A, Murphy D. Vitamin D-induced hypercalcaemia and acute kidney injury in sarcoidosis. BMJ Case Rep 2023;16(1):e250580. PubMed
- Williamson A, Martineau AR, Sheikh A, Jolliffe D, Griffiths CJ. Vitamin D for the management of asthma. Cochrane Database Syst Rev 2023;2(2):CD011511. PubMed
- Kinesya E, Santoso D, Gde Arya N, et al. Vitamin D as adjuvant therapy for diabetic foot ulcers: Systematic review and meta-analysis approach. Clin Nutr ESPEN 2023;54:137-143. PubMed
Phosphatidylserine 9 references
- Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
- Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
- Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
- Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
- Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
- Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
- Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
- Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
- Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC