Durian Ingredients & Drug Interactions
by Hawaii Pharm
What is this page for?
First and foremost: checking Durian against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Durian is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, traditional tonic or aphrodisiac, digestive support.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Durian extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Durian by Hawaii Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Durian by Hawaii Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Durian by Hawaii Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Hawaii Pharm's Durian is a single-ingredient liquid: durian extract. Durian is a tropical fruit, and this extract concentrates its compounds.
The liquid form also contains vegetable palm glycerin, pharmaceutical-grade alcohol, and artesian Hawaiian purified water as inactive ingredients to deliver the extract.
Does it work?
Couldn't assess
We hold no effectiveness data for durian extract in our records, so we can't tell you whether it's shown to work for any particular health purpose.
How safe is it?
Well-documented data
Durian is generally well tolerated as a food in moderation, though it's high in sugar and calories. Case reports describe abdominal discomfort, flatulence, diarrhea, vomiting, and allergic reactions (hives, nasal congestion, runny nose, hoarseness) in some people who ate durian fruit.
The safety data on durian in supplement form is limited, so if you're considering this product—especially in larger amounts or regularly—talk it over with your doctor or pharmacist first. There isn't enough data on file to advise whether it's safe in pregnancy or while breastfeeding.
Meds to double-check
Moderate interaction found
Alcohol (ethanol) is the only medication or substance type with a documented interaction—a Moderate severity concern. If you drink alcohol, talk with your doctor or pharmacist before taking this product.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Durian extract is a single-ingredient supplement with one documented interaction: alcohol. If you drink, check with your doctor or pharmacist before starting it.
The effectiveness data isn't established in our records, and safety information on the supplement form is sparse, so this is worth a conversation with your healthcare provider to decide if it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Durian, straight from the product label.
| Brand | Hawaii Pharm |
|---|---|
| Barcode (UPC) | 650905488153 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Oct 23, 2020 |
| DSLD ID | 237468 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Durian by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Durian extract | 970 mg | -- |
Other ingredients: Vegetable Palm Glycerin, pharmaceutical grade Alcohol, artesian Hawaiian purified Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Hawaii Pharm Herbal Extract Highest quality since 2008
Made with Aloha!
Formulation
Contains no GMO, gluten, artificial colors, heavy metals, preservatives, pesticides, fertilizers.
Super concentrated liquid herbal extract. Dry herb/menstruum ratio: 1:3.
Manufactured in an FDA registered facility.
Non GMO Gluten free
Made in USA, Hawaii
Suggested/Recommended/Usage/Directions
Directions for use: Shake well before using. Take about 20-30 drops (0.7-1 ml, one full squeeze of the dropper bulb) to 2-4 oz of juice or water up to 4 times per day.
Precautions
Warning: Keep out of the reach of children.
May have contraindications. We recommend to seek expert medical advice before taking.
Do not use if you are allergic to any ingredients.
Consult a physician before using during pregnancy, if nursing or taking any medications.
Do not use if seal is broken or missing.
Storage
Store in a cool dry place.
Formula
(Durio zibethinus)
FDA Statement of Identity
Herbal Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
FDA Registered Facility Made in United States of America USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Durian by Hawaii Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Durian by Hawaii Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Durian extract
Interacts with1 drug
Durian is a popular tropical fruit valued mainly as a nutritious food rich in carbohydrates, fiber, vitamins, and antioxidants. While it has many trad...
Durian extract monograph & interactionsOther (inactive) ingredients: Vegetable Palm Glycerin, Pharmaceutical grade Alcohol, Artesian Hawaiian purified Water. These complete the product’s ingredient list but are not active constituents.
Durian by Hawaii Pharm Drug Interactions
HelloPharmacist Interaction Report
Hawaii Pharm's Durian extract has one documented interaction: with alcohol (ethanol), and it's a Moderate severity concern.
There's a traditional belief—and one case report from 1941—that drinking alcohol with durian can be dangerous, though that single report describes a severe outcome (acute bleeding in the pancreas) and no other cases have been published since. A study in mice given durian in ethanol solution was started but the effect text cuts off, so we don't have its full result.
Read the full breakdown — every affected drug type, severity by severity
Alcohol is the only drug type with documented interactions in our data for this ingredient. If you drink alcohol, talk with your doctor or pharmacist before using this product—the evidence is thin, but the potential severity warrants a conversation.
Use the medication checker on this page to scan any other medications or supplements you take, though no other drug interactions are documented in our data for durian extract.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Durian?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Durian interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in Durian interact with drugs. Each result below shows which ingredient is responsible. Durian extract
EthanolEthanol
How Ethanol interacts with Durian — through 1 ingredient. Tap an ingredient for the detail:
Durian ExtractAlcohol (ethanol) Moderate
Interaction Summary
There is a traditional belief that ingestion of alcohol with durian can be fatal.
Read the full Durian Extract + Ethanol interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Durian with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Durian extract
Alcohol (Ethanol)
There is a traditional belief that ingestion of alcohol with durian can be fatal. A case report from 1941 describes an adult in India who developed acute hemorrhagic pancreatitis and died after drinking alcohol with durian, but there have been no other published reports since. A study in mice given homogenized durian fruit flesh in 10% ethanol did not demonstrate any toxicity. However, evidence from in vitro research shows that durian extract can inhibit alcohol dehydrogenase. This activity is similar to the effects of disulfiram. In theory, concomitant use might cause effects similar to disulfiram-ethanol reactions. Until more is known, avoid concomitant use of durian and alcohol.
Brand information
Manufacturer and brand details for Durian, from the product label.
Hawaii Pharm
See all Hawaii Pharm products- Name
- Hawaii Pharm LLC
- City
- Honolulu
- State
- HI
- ZipCode
- 96815
- Web Address
- www.hawaiipharm.com
Durian by Hawaii Pharm: Common Questions
Does Durian by Hawaii Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I drink alcohol?
What side effects have been reported?
Is this safe during pregnancy or breastfeeding?
Is durian extract proven to work for anything?
Why does this liquid contain alcohol?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Durian is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Durian’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Durian's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Durian 5 references
- Singh, P. Journal of the Malaya Branch British Medical Association 1941;5(1):62-63.
- Olivieri, J., Quiliquini-Chambard, A. M., and Hauser, C. Allergy to durian. Allergy 2002;57(3):263.
- Ogle, C. W. and Teh, Y. F. Durian and alcohol. A preliminary report. Singapore Med J 1969;10(4):288-290.
- Maninang JS, Lizada, MCC, Gemma, H. Inhibition of aldehyde dehydrogenase enzyme by Durian (Durio zibethinus Murray) fruit extract. Food Chem 2009;117(2):352-355. DOI
- Husin NA, Rahman S, Karunakaran R, Bhore SJ. A review on the nutritional, medicinal, molecular and genome attributes of Durian (Durio zibethinus L.) the king of fruits in Malaysia. Bioinformation 2018;14(6):265-70. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC