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Dietary supplement

Durian Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Durian is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, traditional tonic or aphrodisiac, digestive support.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Durian (Durio zibethinus) fresh fruit liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Durian by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: a liquid extract made from fresh durian fruit (Durio zibethinus). The extract is suspended in menstruum, an inactive carrier liquid used to preserve and deliver the herbal material.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Durian product and its label doesn't state a use — see Durian's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness ratings for durian in our data, so the evidence for what it may or may not do is not established here. If you're considering this product for a specific purpose, ask your pharmacist what the current research shows.

The evidence, ingredient by ingredient Durian

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Durian is generally safe as a food in moderation, but it's high in sugar and calories. Because this is a supplement form rather than whole fruit, data on safety at supplement doses is limited — the caution is to avoid large amounts and to talk with your provider before starting it.

Case reports describe allergic reactions (hives, nasal congestion, runny nose, and throat discomfort with hoarseness) and gastrointestinal upset (diarrhea and vomiting) in some people who ate durian fruit, though these are uncommon. Pregnancy and breastfeeding safety data is not on file for this ingredient — talk with your doctor or pharmacist about whether it's appropriate for you.

Side effects, ingredient by ingredient Durian

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Durian.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

The one medication interaction we have data for is alcohol (ethanol), rated Moderate severity. If you drink alcohol regularly or plan to have alcoholic beverages, confirm with your doctor or pharmacist before taking this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Durian extract is generally well tolerated as an occasional food, but this supplement form is concentrated and has sparse safety data at higher doses. The main caution is avoiding alcohol — if you drink, check with your doctor or pharmacist first.

Talk it over with your own healthcare provider before starting, especially if you're pregnant, breastfeeding, or managing a health condition.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Durian, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7429523590516
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Nov 21, 2020
DSLD ID 233824
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Durian by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
7429523590516
IngredientAmount% DV
Durian (Durio zibethinus) fresh fruit liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Origin of plant material: Thailand.

Manufactured in the USA in an FDA registered facility

Sugar free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Durio zibethinus

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

See for yourself

Durian by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Durian by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

970 mg per serving

Durian is a popular tropical fruit valued mainly as a nutritious food rich in carbohydrates, fiber, vitamins, and antioxidants. While it has many trad...

Durian (Durio zibethinus) fresh fruit liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Durian by Herbal Terra Drug Interactions

Want to check YOUR meds against Durian?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Durian with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Durian (Durio zibethinus) fresh fruit liquid extract1 drug type · 1 drug

Alcohol (Ethanol)

There is a traditional belief that ingestion of alcohol with durian can be fatal. A case report from 1941 describes an adult in India who developed acute hemorrhagic pancreatitis and died after drinking alcohol with durian, but there have been no other published reports since. A study in mice given homogenized durian fruit flesh in 10% ethanol did not demonstrate any toxicity. However, evidence from in vitro research shows that durian extract can inhibit alcohol dehydrogenase. This activity is similar to the effects of disulfiram. In theory, concomitant use might cause effects similar to disulfiram-ethanol reactions. Until more is known, avoid concomitant use of durian and alcohol.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Durian, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

Durian by Herbal Terra: Common Questions

Does Durian by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Durian has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Durian contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I drink alcohol?
No — there's a documented Moderate interaction between durian and alcohol. A traditional belief holds the combination can be fatal, and a 1941 case report described a death from acute pancreatitis after combining them. Talk with your doctor or pharmacist before taking this product if you drink alcohol.
Is durian safe during pregnancy or breastfeeding?
Safety data for this ingredient during pregnancy and breastfeeding is not on file in our data. Because this is a concentrated extract (not whole fruit), the dose may exceed what's typical from eating fresh durian. Talk with your doctor or pharmacist for personalized advice.
What does durian do?
We don't hold effectiveness ratings for durian in our data, so I can't tell you what research shows it does or doesn't do. Ask your pharmacist what the current evidence supports.
Can I have an allergic reaction to this?
Yes — case reports describe allergic reactions to durian fruit, including hives, nasal congestion, runny nose, and throat discomfort with hoarseness. If you've never eaten durian before, start carefully and watch for any signs of a reaction.
What inactive ingredients are in this?
The extract is carried in menstruum, a liquid used to preserve and deliver the herbal material. That's the only inactive ingredient listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Durian label
Sources

Sources & How We Checked

Durian's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Durian 5 references
  1. Singh, P. Journal of the Malaya Branch British Medical Association 1941;5(1):62-63.
  2. Olivieri, J., Quiliquini-Chambard, A. M., and Hauser, C. Allergy to durian. Allergy 2002;57(3):263.
  3. Ogle, C. W. and Teh, Y. F. Durian and alcohol. A preliminary report. Singapore Med J 1969;10(4):288-290.
  4. Maninang JS, Lizada, MCC, Gemma, H. Inhibition of aldehyde dehydrogenase enzyme by Durian (Durio zibethinus Murray) fruit extract. Food Chem 2009;117(2):352-355. DOI
  5. Husin NA, Rahman S, Karunakaran R, Bhore SJ. A review on the nutritional, medicinal, molecular and genome attributes of Durian (Durio zibethinus L.) the king of fruits in Malaysia. Bioinformation 2018;14(6):265-70. PubMed

See these in context on the Durian monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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