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Dietary supplement

E Zhu Ingredients & Drug Interactions

by Herbal Terra

E Zhu label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking E Zhu against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

E Zhu is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for digestive upset and bloating, loss of appetite, menstrual discomfort.Based on those ingredients, 643 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are wildcrafted E Zhu (Curcuma zedoaria) dried root liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against E Zhu by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with E Zhu by Herbal Terra — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of E Zhu by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

E Zhu contains one active ingredient: a liquid extract of wildcrafted E Zhu root (Curcuma zedoaria), a traditional plant from Southeast Asia. The extract is concentrated by soaking the dried root in a menstruum — a liquid solvent — to pull out the plant's active compounds.

The menstruum itself is an inactive ingredient used to carry the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Zedoary product and its label doesn't state a use — see Zedoary's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold rates E Zhu's effectiveness as insufficient to establish for the conditions listed — rotaviral diarrhea and high cholesterol. That means the data available isn't reliable enough yet to say whether it works or doesn't work for those uses.

If you're considering it for one of these conditions, talk with your doctor or pharmacist about what the current evidence supports.

The evidence, ingredient by ingredient Zedoary

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

E Zhu is generally used in food amounts, but human safety data for supplement doses is limited — we know less about how it behaves at higher doses than at culinary levels. The safety data advises against use during pregnancy because zedoary has traditionally been avoided due to potential effects on the uterus, and there isn't enough modern safety research to clear it.

There's no reliable safety information during breastfeeding either, so it's best avoided then as well. No adverse effects were reported in the data we hold.

Side effects, ingredient by ingredient Zedoary

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Zedoary.
  • The most serious interaction on file is rated Moderate.
  • For scale: 644 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking E Zhu, check whether you take any CYP3A4 substrate medications — the enzyme involved in breaking down a very large group of drugs including certain cancer treatments, heart medications, blood pressure drugs, immunosuppressants, and statins. Use the interaction checker on this page with your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

E Zhu may be worth considering if you're interested in traditional uses and your medications don't involve CYP3A4 metabolism — but that's a big 'if' given how many drugs use that pathway. If you're pregnant, breastfeeding, or taking any prescription medication, check with your pharmacist first.

The safety data for supplement doses isn't robust, so personalized advice matters here.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about E Zhu, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7429523692678
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Nov 21, 2020
DSLD ID 233942
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for E Zhu by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
7429523692678
IngredientAmount% DV
wildcrafted E Zhu (Curcuma zedoaria) dried root liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Manufactured in the USA in an FDA registered facility

Sugar free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Curcuma zedoaria

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

E Zhu by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

E Zhu label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in E Zhu by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Wildcrafted E Zhu (Curcuma zedoaria) dried root liquid extract

Interacts with
643 drugs
970 mg per serving

Zedoary is a ginger-family root used in traditional Asian and Indian medicine, mostly for digestion and as a spice. Scientific evidence in humans is v...

Wildcrafted E Zhu (Curcuma zedoaria) dried root liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

E Zhu by Herbal Terra Drug Interactions

Want to check YOUR meds against E Zhu?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
643Drugs
643 Moderate

Ingredients driving the most interactions

wildcrafted E Zhu (Curcuma zedoaria) dried root liquid extract 643

Individual Drug Interactions

The ingredients in E Zhu interact with 643 drugs. Click any drug to see the details.

1 of the 1 ingredient in E Zhu interact with drugs. Each result below shows which ingredient is responsible. wildcrafted E Zhu (Curcuma zedoaria) dried root liquid extract

Each ingredient & the kinds of drugs it affects

For each ingredient in E Zhu with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wildcrafted E Zhu (Curcuma zedoaria) dried root liquid extract1 drug type · 643 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, zedoary might increase levels of drugs metabolized by CYP3A4.
In-vitro research shows that a methanol extract of zedoary strongly inhibits the CYP3A4 metabolism of the tyrosine kinase inhibitors lapatinib and sorafenib, and to a lesser extent, gefitinib.

Likelihood Possible Evidence D
wildcrafted E Zhu (Curcuma zedoaria) dried root liquid extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for E Zhu, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

E Zhu by Herbal Terra: Common Questions

Does E Zhu by Herbal Terra interact with any medications?
Yes. Based on its ingredients, E Zhu has a known interaction with 643 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
E Zhu contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take E Zhu if I'm pregnant?
No. E Zhu is rated likely unsafe in pregnancy because it may affect the uterus, and there isn't enough modern safety data to change that assessment. If you're pregnant or planning to become pregnant, avoid it and talk with your doctor about alternatives.
Is E Zhu safe while breastfeeding?
No reliable safety information exists for breastfeeding, so it's best avoided. Talk with your doctor or pharmacist about whether it's right for you.
What is E Zhu actually used for?
In our data, E Zhu is listed for rotaviral diarrhea and high cholesterol, but the evidence for both is insufficient to establish whether it works. It's been used traditionally in Southeast Asian medicine, but modern research hasn't confirmed its effectiveness for these conditions yet.
Does E Zhu have side effects?
No adverse effects were reported in the data we hold, though human safety information for supplement doses is limited. Because supplement research often lags behind use, if you experience anything unusual, tell your pharmacist or doctor.
What's in the bottle besides the active ingredient?
The extract is suspended in a menstruum — a liquid solvent used to carry the plant compounds. That's the only other ingredient listed; there are no fillers or binders in this formulation.
Will E Zhu change how my medications work?
Possibly. E Zhu can slow down how your liver breaks down a very large group of medications, which may raise their levels and effects. Use the interaction checker on this page with your exact drugs to find out.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

E Zhu label
Go deeper

The Full Monographs Behind E Zhu’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Zedoary

Interacts with 643 drugs

Zedoary is a ginger-family root used in traditional Asian and Indian medicine, mostly for digestion and as a spice. Scientific evidence in humans is very limited, so its benefits are not wel...

Read the full Zedoary monograph →
Sources

Sources & How We Checked

E Zhu's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Zedoary 5 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Tariq S, Imran M, Mushtaq Z, Asghar N. Phytopreventive antihypercholesterolemic and antilipidemic perspectives of zedoary (Curcuma Zedoaria Roscoe) herbal tea. Lipids Health Dis 2016;15:39. doi: 10.1186/s12944-016-0210-y.
  4. Rodseeda C, Yamanont P, Pinthong D, Korprasertthaworn P. Inhibitory effects of Thai herbal extracts on the cytochrome P450 3A-mediated the metabolism of gefitinib, lapatinib and sorafenib. Toxicol Rep 2022;9:1846-1852. PubMed
  5. Niu LQ, Xiao L, Cai QH, et al. Comparative effectiveness of Chinese herbal injections treating for rotavirus enteritis in children: A systematic review and Bayesian network meta-analysis. Integr Med Res 2023;12(2):100944. PubMed

See these in context on the Zedoary monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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