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Dietary supplement

Release Intestinal Biofilm Cleanser Ingredients & Drug Interactions

by Body Ecology

Release Intestinal Biofilm Cleanser label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Release Intestinal Biofilm Cleanser against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Release Intestinal Biofilm Cleanser is a dietary supplement by Body Ecology with 8 active ingredients. Its ingredients are commonly taken for food and drink flavoring or sourness, preservative and acidity adjuster, kidney stone prevention (as citrate salts).Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Release Intestinal Biofilm Cleanser by Body Ecology

Ask about any prescription or over-the-counter medication and we check it for interactions with Release Intestinal Biofilm Cleanser by Body Ecology — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Release Intestinal Biofilm Cleanser by Body Ecology

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 3 of its 8 active ingredients.
  • “Proprietary EcoOxyZyme Blend” is a proprietary blend — the label gives one combined amount (570 mg) without saying how much of each component you get.
  • “pHloraMax” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Release Intestinal Biofilm Cleanser contains 8 active ingredients, most of them digestive enzymes designed to break down different components of biofilm in your gut. Protease breaks down proteins, while xylanase, beta-glucanase, hemicellulase, and chitinase target different structural compounds like cellulose and chitin.

The formula also includes citric acid (an acid that lowers pH), potassium, and a proprietary blend called EcoOxyZyme plus a component called pHloraMax. Complex oxides of magnesium round out the formula.

The product comes in capsules with only hydroxypropyl methylcellulose and water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: disrupt intestinal biofilms and support healthy intestinal flora.
  • We looked for evidence on: Dysbiosis, Intestinal permeability, Leaky gut, Bacterial overgrowth.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We don't hold effectiveness data for the enzyme ingredients in this product or for the other actives listed. The evidence supporting whether this product actually works to cleanse biofilm isn't established in our monographs, so we can't tell you how well it performs for that stated purpose.

The evidence, ingredient by ingredient Citric Acid Potassium Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease is generally well tolerated but may cause digestive upset or allergic reactions in some people; occupational exposure to similar enzymes has rarely triggered allergies like asthma and hay fever. Citric acid at the small amounts in most supplements appears safe, though topically it can cause mild irritation and sun sensitivity.

Potassium from food is fine, but supplements can dangerously raise blood potassium levels, especially in people with kidney disease — common symptoms of too-high potassium include nausea, vomiting, abdominal pain, and diarrhea, with serious cases causing irregular heartbeat or heart block. During pregnancy, protease safety has not been established and is best avoided unless your doctor prescribes it.

Citric acid is likely safe in pregnancy. Potassium from diet is fine during pregnancy, but supplements should only be used under medical guidance.

For breastfeeding, protease has little safety data and isn't recommended without advice from your doctor or pharmacist; citric acid is likely safe, and dietary potassium is appropriate, though supplements need your doctor's approval.

Side effects, ingredient by ingredient Citric Acid Potassium Proteolytic Enzymes (proteases)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take potassium-sparing diuretics (water pills that keep potassium in your body), ACE inhibitors, or angiotensin receptor blockers (ARBs) for blood pressure or heart disease, you need to discuss this product with your pharmacist before you take it — the potassium it contains can raise your blood potassium to unsafe levels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is aimed at people interested in gut health through enzyme-based biofilm support, but the evidence for whether it works isn't established in our data. If you take blood pressure meds, water pills, or have kidney problems, talk to your pharmacist or doctor before starting — the potassium content matters.

Pregnant or breastfeeding? Check with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Release Intestinal Biofilm Cleanser, straight from the product label.

Brand Body Ecology
Barcode (UPC) 758000100267
Net contents 60 Delayed Release Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 314769
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Release Intestinal Biofilm Cleanser by Body Ecology, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
758000100267
IngredientAmount% DV
Protease0 NP--
Xylanase0 NP--
Beta-Glucanase0 NP--
Citric Acid15 mg--
Hemicellulase0 NP--
Potassium8 mg1%
Chitinase0 NP--
Proprietary EcoOxyZyme Blend570 mg--
pHloraMax0 NP--
Complex Oxides of Magnesium200 mg47%

Other ingredients: Hydroxypropyl Methylcellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Body Ecology Release Intestinal Biofilm Cleanser is a proprietary complex of ozone, peroxide, and other oxidants, combined with enzymes, designed to disrupt biofilms.

Suggested/Recommended/Usage/Directions

Recommended usage: Take one (1) capsule two times a day with meals, or more if needed to achieve desired results.

Formulation

Biofilms occur when microbes attach to a surface and form a barrier to protect the community inside. One would then focus on repairing the gut lining and creating a healthy inner ecosystem.

Supports healthy intestinal flora

Gluten Free

Storage

Store in a cool, dry place.

Precautions

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Release Intestinal Biofilm Cleanser by Body Ecology label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Release Intestinal Biofilm Cleanser label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Release Intestinal Biofilm Cleanser by Body Ecology

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Citric Acid

No known
interactions
15 mg per serving

Citric acid is a natural acid found in citrus fruits and is widely used as a safe food additive, flavoring, and preservative. In medicine, citrate for...

Citric Acid monograph & interactions

Potassium

Interacts with
62 drugs
8 mg per serving Form: Potassium Chloride

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Proprietary EcoOxyZyme Blend

570 mg per serving
  • › Protease
  • › Xylanase
  • › Beta-Glucanase
  • › Hemicellulase
  • › Chitinase
  • › PHloraMax

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Release Intestinal Biofilm Cleanser by Body Ecology Drug Interactions

Want to check YOUR meds against Release Intestinal Biofilm Cleanser?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium 62

Individual Drug Interactions

The ingredients in Release Intestinal Biofilm Cleanser interact with 62 drugs. Click any drug to see the details.

1 of the 8 ingredients in Release Intestinal Biofilm Cleanser interact with drugs. Each result below shows which ingredient is responsible. Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Release Intestinal Biofilm Cleanser with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Release Intestinal Biofilm Cleanser, from the product label.

Body Ecology

See all Body Ecology products
Name
Body Ecology
City
Charleston
State
SC
ZipCode
29403
Phone Number
800-511-2660
Pharmacist Counseling Corner

Release Intestinal Biofilm Cleanser by Body Ecology: Common Questions

Does Release Intestinal Biofilm Cleanser by Body Ecology interact with any medications?
Yes. Based on its ingredients, Release Intestinal Biofilm Cleanser has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Release Intestinal Biofilm Cleanser contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly are these enzymes supposed to do?
This product contains multiple digestive enzymes — protease breaks down proteins, and others target cellulose, chitin, and related compounds — all designed to help break down biofilm buildup in your intestines. However, we don't have data on how effectively they actually do this.
Will this upset my stomach?
Protease may cause digestive upset in some people, though it's generally well tolerated. Citric acid at these levels is typically fine. If you have a sensitive gut, start with a low dose and see how your body responds.
Can I take this if I have kidney disease?
No — potassium supplements can dangerously raise your blood potassium levels, and your kidneys control how much potassium your body holds. Talk to your doctor or pharmacist before using any supplement with potassium if you have kidney problems.
Is this safe during pregnancy?
Protease safety hasn't been established in pregnancy and is best avoided unless your doctor says otherwise. Citric acid is likely safe, and dietary potassium is fine — but potassium supplements need your doctor's approval. Talk to your healthcare provider to be sure.
Can I take this with my blood pressure medicine?
It depends on which one. If you take an ACE inhibitor, an ARB, or a potassium-sparing diuretic, this product's potassium content can cause a dangerous interaction. Check with your pharmacist about your specific medication before starting.
Are there any fillers or extra stuff in here?
The capsule itself is hydroxypropyl methylcellulose (a plant-based capsule material), and there's water — beyond that, all eight ingredients listed are the active formula, so you're getting mostly enzyme and nutrient content.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Release Intestinal Biofilm Cleanser label
Go deeper

The Full Monographs Behind Release Intestinal Biofilm Cleanser’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Citric Acid

Citric acid is a natural acid found in citrus fruits and is widely used as a safe food additive, flavoring, and preservative. In medicine, citrate forms (like potassium or sodium citrate) ar...

Read the full Citric Acid monograph → Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Proteolytic Enzymes (proteases)

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...

Read the full Proteolytic Enzymes (proteases) monograph →
Sources

Sources & How We Checked

Release Intestinal Biofilm Cleanser's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 25 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Citric Acid 10 references
  1. Kurtzweil P. Alpha-hydroxy acids for skin care: Smooth sailing or rough seas? FDA 1999. Available at: /www.fda.gov/fdac/features/1998/298_ahas.html (Accessed 18 August 2000). DOI
  2. Erbagci Z, Akcali C. Biweekly serial glycolic acid peels vs. long-term daily use of topical low-strength glycolic acid in the treatment of atrophic acne scars. Int J Dermatol 2000;39:789-94.. PubMed
  3. Ghadishah D, Gorchynski J. Airway compromise after routine alpha-hydroxy facial peel administration. J Emerg Med 2002;22:353-5.. PubMed
  4. Baumann LS, Oresajo C, Yatskayer M, Dahl A, Figueras K. Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment
  5. Emtestam L, Svensson Å, Rensfeldt K. Treatment of seborrhoeic dermatitis of the scalp with a topical solution of urea, lactic acid, and propylene glycol (K301): results of two double-blind, randomised, placebo-controlled studies. Mycoses. 2012 Sep;55(5):3 PubMed
  6. Kaminaka C, Uede M, Matsunaka H, Furukawa F, Yamomoto Y. Clinical evaluation of glycolic acid chemical peeling in patients with acne vulgaris: a randomized, double-blind, placebo-controlled, split-face comparative study. Dermatol Surg. 2014 Mar;40(3):314- PubMed
  7. Köse O, Özmen I, Arca E. An open, comparative study of 10% potassium hydroxide solution versus salicylic and lactic acid combination in the treatment of molluscum contagiosum in children. J Dermatolog Treat. 2013 Aug;24(4):300-4. PubMed
  8. Vachiramon V, Sahawatwong S, Sirithanabadeekul P. Treatment of melasma in men with low-fluence Q-switched neodymium-doped yttrium-aluminum-garnet laser versus combined laser and glycolic acid peeling. Dermatol Surg. 2015 Apr;41(4):457-65. PubMed
  9. US Food and Drug Administration (FDA). Cosmetic Ingredients: Alpha Hydroxy Acids. August 2020. Available at: https://www.fda.gov/cosmetics/cosmetic-ingredients/alpha-hydroxy-acids. Accessed on October 19, 2021.
  10. Ormerod AD, van Voorst Vader PC, Majewski S, Vanscheidt W, Benjamin N, van der Meijden W. Evaluation of the efficacy, safety, and tolerability of 3 dose regimens of topical sodium nitrite with citric acid in patients with anogenital warts: A randomized cl DOI

See these in context on the Citric Acid monograph →

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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