Elder Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Elder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Elder is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for cold and flu symptoms, immune support, fever and congestion (traditional).Based on those ingredients, 644 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Elder flower (Sambucus nigra) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Elder by Herb Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Elder by Herb Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Elder by Herb Pharm
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — American Elder.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: lithium.
- For scale: 645 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Elder, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090700001476 |
| Net contents | 4 fl. Oz.; 120 mL |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2019 |
| DSLD ID | 203874 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Elder by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Elder flower (Sambucus nigra) extract | 636 mg | -- |
Other ingredients: certified organic Cane Alcohol, distilled Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Shake well before using Add 1 full squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 5 times per day. Best taken between meals.
Precautions
Keep out of the reach of children
Storage
Store away from heat & light
Formula
Sambucus nigra
Elder Liquid Extract
We prepare our Elder Extract from the whole flower of certified organically grown Sambucus nigra trees.
General Statements
Optimal well-being
Dry herb/menstruum ratio: 1:5
Seals/Symbols
USDA Organic
FDA Statement of Identity
Herbal Supplement
Formulation
Gluten-Free
Certified organic by Organic Certifiers
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Elder by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Elder by Herb Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container168 Amounts shown are per serving.
Elder flower (Sambucus nigra) extract
Interacts with644 drugs
American elder is a North American plant whose cooked, ripe berries and flowers are used mainly for colds, flu, and general immune support. The scienc...
Elder flower (Sambucus nigra) extract monograph & interactionsOther (inactive) ingredients: Certified organic Cane Alcohol, Distilled Water. These complete the product’s ingredient list but are not active constituents.
Elder by Herb Pharm Drug Interactions
Elder contains a single active ingredient, and it has known interactions with 644 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Elder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Elder interact with 644 drugs. Click any drug to see the details.
1 of the 1 ingredient in Elder interact with drugs. Each result below shows which ingredient is responsible. Elder flower (Sambucus nigra) extract
ApremilastOtezla
How Apremilast interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Apremilast interactionAprepitantCinvanti, Emend
How Aprepitant interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aprepitant interactionAripiprazoleAbilify, Abilify Maintena, Abilify Mycite
How Aripiprazole interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aripiprazole interactionAripiprazole LauroxilAristada, Aristada Initio Kit
How Aripiprazole Lauroxil interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aripiprazole Lauroxil interactionArmodafinilNuvigil
How Armodafinil interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Armodafinil interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Hydrocodone interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Aspirin, Omeprazole interactionAtazanavirReyataz
How Atazanavir interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Atazanavir interactionAtazanavir, CobicistatEvotaz
How Atazanavir, Cobicistat interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Atazanavir, Cobicistat interactionAtogepantQulipta
How Atogepant interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Atogepant interactionAtorvastatinAtorvaliq
How Atorvastatin interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Atorvastatin interactionAtorvastatin CalciumLipitor
How Atorvastatin Calcium interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Atorvastatin Calcium interactionAtropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, ScopolamineAtrohist Plus, Pro Tuss, Ru-tuss, Stahist
How Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interactionAvacopanTavneos
How Avacopan interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Avacopan interactionAvanafilStendra
How Avanafil interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Avanafil interactionAvapritinibAyvakit
How Avapritinib interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Avapritinib interactionAxitinibInlyta
How Axitinib interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Axitinib interactionAzelastine Hydrochloride, Fluticasone PropionateDymista
How Azelastine Hydrochloride, Fluticasone Propionate interacts with Elder — through 1 ingredient. Tap an ingredient for the detail:
Elder Flower (sambucus Nigra) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
Read the full Elder Flower (sambucus Nigra) Extract + Azelastine Hydrochloride, Fluticasone Propionate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Elder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Elder flower (Sambucus nigra) extract
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, taking American elder might increase levels of CYP3A4 substrates.
In vitro research shows that American elder inhibits CYP3A4 enzymes.
Lithium
Theoretically, American elder might reduce excretion and increase levels of lithium.
American elder is thought to have diuretic properties. Theoretically, American elder might reduce the excretion of lithium, increasing serum levels.
Brand information
Manufacturer and brand details for Elder, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Elder by Herb Pharm: Common Questions
Does Elder by Herb Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Elder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Elder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Elder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
American Elder 2 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC