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Dietary supplement

Elderberry 750 Ingredients & Drug Interactions

by Purely Beneficial

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Elderberry 750 is a dietary supplement by Purely Beneficial with 1 active ingredient. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Elderberry Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Elderberry 750 by Purely Beneficial

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Elderberry Blend” is a proprietary blend — the label gives one combined amount (750 mg) without saying how much of each component you get.

This 2-ingredient capsule contains elderberry extract and elderberry as its active ingredients, along with methylcellulose as an inactive binder. The extract form concentrates the active compounds from the ripe berries, while the capsule makes it convenient to take.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Elderberry's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Immune support.
  • We looked for evidence on: Respiratory tract infections, Upper respiratory tract infection (URTI), Lower respiratory tract infections, Colds, Influenza.
  • The closest evidence on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).
  • Also on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI), Lower respiratory tract infections.

The evidence for elderberry's effectiveness isn't established yet in the data we hold. Claims about hay fever, heart disease, chronic fatigue, COPD, brain function, and respiratory tract infections all have insufficient reliable evidence to rate them.

That doesn't mean elderberry doesn't work — it means the studies so far haven't been strong enough to say for certain.

The evidence, ingredient by ingredient Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Elderberry extracts made from ripe fruit are generally well tolerated. The real risk comes from raw or unripe berries, seeds, leaves, or bark — those contain compounds (cyanogenic glycosides) that cooking destroys, and can cause nausea, vomiting, severe diarrhea, weakness, dizziness, numbness, and confusion.

This product should be safe on that front if it's properly prepared. There isn't enough reliable safety data to recommend elderberry supplements during pregnancy or while breastfeeding — the evidence just isn't there either way.

Talk with your doctor or pharmacist before taking it if you're pregnant or nursing. One rare case report linked elderberry to liver inflammation in someone with an underlying autoimmune disease, though that's uncommon.

Side effects, ingredient by ingredient Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Elderberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Elderberry 750, double-check with your pharmacist or doctor if you take immunosuppressants or pazopanib (Votrient). Both are Moderate severity concerns — the supplement may interfere with how these medications work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're on an immunosuppressant (like after a transplant) or taking pazopanib for cancer, you'll want to clear this with your doctor or pharmacist first. Elderberry extracts from ripe fruit are generally well tolerated, but we don't yet have solid evidence it works for the conditions people often take it for.

Talk it over with your own provider before starting — they know your health picture best.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Elderberry 750, straight from the product label.

Brand Purely Beneficial
Barcode (UPC) 046708995507
Net contents 180 Veggie Cap(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 276533
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Elderberry 750 by Purely Beneficial, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
UPC/BARCODE
046708995507
IngredientAmount% DV
Elderberry extract0 NP--
Elderberry Blend750 mg--
Elderberry0 NP--

Other ingredients: Methylcellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one (1) capsule daily preferably with meals, or as directed by a physician. Additional capsules may be taken as needed.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practice Consistent Quality Made in the USA with global ingredients

General Statements

Please Recycle

100% Satisfaction Guaranteed

Formulation

Immune support

Does not contain: Fillers, artificial ingredients, preservatives, soy, gluten, dairy, gelatin, flavoring, coloring.

Made with organic elderberry

Formula

Antioxidants

FDA Statement of Identity

Dietary Supplement

See for yourself

Elderberry 750 by Purely Beneficial label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Elderberry 750 by Purely Beneficial

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Elderberry Blend

Interacts with
121 drugs
750 mg per serving

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Elderberry Blend monograph & interactions

Other (inactive) ingredients: Methylcellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Elderberry 750 by Purely Beneficial Drug Interactions

Want to check YOUR meds against Elderberry 750?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

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121Drugs
121 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Elderberry 750 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Elderberry Blend2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Elderberry 750, from the product label.

Purely Beneficial

See all Purely Beneficial products
Name
Purely Beneficial, Inc.
Street Address
836 57th Street, Ste 413
City
Sacramento
State
CA
ZipCode
95819
Pharmacist Counseling Corner

Elderberry 750 by Purely Beneficial: Common Questions

Does Elderberry 750 by Purely Beneficial interact with any medications?
Yes. Based on its ingredients, Elderberry 750 has a known interaction with 121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Elderberry 750 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
There isn't enough reliable safety information on elderberry supplements in pregnancy to say it's safe. Talk with your doctor or pharmacist about whether this is right for you — they can weigh the risks and benefits for your situation.
Can I take this while breastfeeding?
Same situation as pregnancy — there's not enough reliable safety data. Check with your doctor or pharmacist before starting it.
What side effects might I get?
Properly prepared elderberry extracts from ripe fruit are generally well tolerated and side effects are uncommon. If you ingest raw or unripe berries, seeds, leaves, or bark, you could get nausea, vomiting, diarrhea, weakness, dizziness, or numbness — but those shouldn't be in this product if it's made correctly.
Does elderberry actually work for colds or the flu?
The evidence isn't there yet — we hold insufficient reliable evidence to say it works for respiratory tract infections or other common reasons people take it. That doesn't mean it doesn't; it means the research hasn't been strong enough to confirm it.
I have an autoimmune disease. Is this safe for me?
Because elderberry stimulates your immune system, it might not be the right choice if you're managing an autoimmune condition. One rare case report linked it to liver inflammation in someone with underlying autoimmune disease. Talk with your doctor or pharmacist before taking it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Elderberry 750 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Elderberry 750 label
Sources

Sources & How We Checked

Elderberry 750's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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