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Dietary supplement

Elderberry Sambucus Syrup Ingredients & Drug Interactions

by SR Sports Research

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Elderberry Sambucus Syrup is a dietary supplement by SR Sports Research with 1 active ingredient. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Elderberry juice concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Elderberry Sambucus Syrup by SR Sports Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Black Elderberry juice concentrate” is listed as a grouped ingredient — the label gives one combined amount (2.50 Gram(s)) without saying how much of each component you get.

This is a single-ingredient product: black elderberry in liquid form. The syrup also contains vegetable glycerin, purified water, and citric acid as inactive ingredients to preserve it and give it consistency.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: immune support and respiratory health.
  • We looked for evidence on: Upper respiratory tract infection (URTI), Respiratory tract infections, Lower respiratory tract infections, Rhinosinusitis, flu, common cold — and 1 related terms.
  • The closest evidence on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).
  • Also on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Rhinosinusitis, Upper respiratory tract infection (URTI), Lower respiratory tract infections.

The evidence isn't established in our data for what this product is commonly used for. Our monograph on elderberry rates it as having insufficient reliable evidence for allergic rhinitis (hay fever), cardiovascular disease, chronic fatigue syndrome, chronic obstructive pulmonary disease, cognitive function, and respiratory tract infections.

That doesn't mean it doesn't work — it means the evidence we have isn't strong enough yet to say one way or the other.

The evidence, ingredient by ingredient Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Properly cooked elderberry products like this syrup are generally well tolerated. The main safety concern is raw or unripe berries, leaves, bark, and seeds, which contain a compound that can cause nausea, vomiting, severe diarrhea, weakness, dizziness, numbness, and confusion — but cooking eliminates that toxin, and this is a prepared syrup.

There isn't enough reliable safety information to recommend elderberry supplements during pregnancy or while breastfeeding, so you should avoid them at those times. One case report linked long-term elderberry use to autoimmune hepatitis (liver inflammation) in a person with an underlying autoimmune disease, so if that's you, talk with your doctor or pharmacist first.

Side effects, ingredient by ingredient Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Elderberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before you start if you take immunosuppressants (such as medications after a transplant or for severe autoimmune disease) or pazopanib for cancer. Both carry moderate interaction risk with elderberry.

Your pharmacist can search your exact medications using the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Elderberry syrup is generally well tolerated if you're taking no immunosuppressants and not on pazopanib. If you take any prescription medication — especially those — check with your pharmacist or use the search tool on this page before you start.

Pregnant or breastfeeding? Skip it and talk with your doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Elderberry Sambucus Syrup, straight from the product label.

Brand SR Sports Research
Barcode (UPC) 023249090076
Net contents 4 Fluid Ounce(s); 120 Milliliter(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 268441
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Elderberry Sambucus Syrup by SR Sports Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 mL
Maximum serving Sizes:
10 mL
Servings per container
12
UPC/BARCODE
023249090076
IngredientAmount% DV
Calories40 Calorie(s)--
Total Carbohydrates9 Gram(s)3%
Total Sugars1 Gram(s)--
Black Elderberry12000 mg--
Black Elderberry juice concentrate2.5 Gram(s)--

Other ingredients: Vegetable Glycerin, Water, Purified, Citric Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Each serving made from 12,000 mg of black elderberries.

12,000 of black elderberries per serving

2.5 g (2500 mg) per serving equivalent to 12 g (12,000 mg) of fresh black elderberries.

Suggested/Recommended/Usage/Directions

Options to Enjoy Add to herbal tea Enjoy a teaspoonful Infuse in water

Suggested Use: As a dietary supplement, healthy adults take 2 teaspoons daily. Best when taken as directed by a qualified healthcare professional. Shake well before use.

General Statements

Quality Matters

Please recycle 90 Days money back guarantee Satisfaction Guarantee We offer a full refund on the purchase price of your order (minus return cost) within 90 days of purchase. Restrictions apply. Please visit sportsresearch.com for full details. Instagram Facebook YouTube Snapchat Twitter @sportsresearch

May be used with other SR Elderberry products.

Formulation

Certified Vegan vegan.org

Gluten free

Manufactured and Quality Tested in USA. Ingredients carefully sourced from around the world.

Non-gmo

Vegan

Seals/Symbols

Certified Vegan vegan.org Non GMO Project Verified nongmoproject.org

FDA Statement of Identity

Dietary Supplement

Precautions

Caution: Keep out of reach of children and pets.

Caution: Keep out of reach of children and pets. Consult with a qualified healthcare professional prior to using this product. Do not exceed recommended daily intake. Do not use if safety seal is damaged or missing.

Storage

Store at room temperature, in a dry place. Refrigeration is not required, but highly recommended. Protect product from excessive heat, freezing, humidity and light.

See for yourself

Elderberry Sambucus Syrup by SR Sports Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Elderberry Sambucus Syrup by SR Sports Research

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size10 mL Dosage formLiquid Servings per container12 Amounts shown are per serving.

Black Elderberry juice concentrate

Interacts with
121 drugs
2.5 Gram(s) per serving

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Black Elderberry juice concentrate monograph & interactions

Other (inactive) ingredients: Vegetable Glycerin, Water, Purified, Citric Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Elderberry Sambucus Syrup by SR Sports Research Drug Interactions

Want to check YOUR meds against Elderberry Sambucus Syrup?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
121Drugs
121 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Elderberry Sambucus Syrup with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Black Elderberry juice concentrate2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Elderberry Sambucus Syrup, from the product label.

SR Sports Research

See all SR Sports Research products
Name
Sports Research
Street Address
784 Channel St.
City
San Pedro
State
CA
ZipCode
90731
Phone Number
(310) 519-1484
Web Address
sportsresearch.com
Pharmacist Counseling Corner

Elderberry Sambucus Syrup by SR Sports Research: Common Questions

Does Elderberry Sambucus Syrup by SR Sports Research interact with any medications?
Yes. Based on its ingredients, Elderberry Sambucus Syrup has a known interaction with 121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Elderberry Sambucus Syrup contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy or while breastfeeding?
No — there isn't enough reliable safety information, so it's best to avoid elderberry supplements at those times. Talk with your doctor or pharmacist about what's safe for you.
What are the side effects?
Properly prepared elderberry products are generally well tolerated. The risks come from raw or unripe berries, leaves, bark, and seeds — but this is a cooked syrup, so that shouldn't be an issue. Rare cases of nausea or vomiting have been reported, usually with mixed products. One case linked long-term use to liver inflammation in someone with an autoimmune disease.
Does elderberry actually work for colds or the flu?
The evidence we hold rates it as having insufficient reliable evidence for respiratory tract infections and related conditions. More research is needed to know for sure.
Can I take this if I have an autoimmune disease?
Talk with your doctor or pharmacist first. Elderberry stimulates your immune system, which may not be right for you if you're already managing an autoimmune condition. One case also linked long-term use to liver inflammation in a person with autoimmune disease.
What's 'black elderberry juice concentrate' in the ingredient list?
It's part of how the black elderberry is delivered in this liquid formula — its component parts are the same as the black elderberry ingredient listed, so there's still just one active ingredient in the product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Elderberry Sambucus Syrup is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Elderberry Sambucus Syrup label
Go deeper

The Full Monographs Behind Elderberry Sambucus Syrup’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Elderberry Sambucus Syrup's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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