No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Extra Strength Biotin 2500 mcg Ingredients & Drug Interactions

by Nature Made

Softgel Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Extra Strength Biotin 2500 mcg is a dietary supplement by Nature Made with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Extra Strength Biotin 2500 mcg by Nature Made

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: biotin, a B vitamin your body needs for hair, skin, and nail health, and for converting food into energy. The softgel also contains inactive ingredients (soybean oil, gelatin, glycerin, yellow beeswax, water, rapeseed lecithin, and colors) that help deliver the biotin.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support healthy hair, skin and nails.
  • We looked for evidence on: Biotin deficiency, Brittle nails, hair loss, skin condition, nail health.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails.

Biotin is likely effective for biotin deficiency—which is rare but can happen with certain conditions or medications. For hair loss (alopecia areata), the evidence isn't established enough to rate it.

For multiple sclerosis and seborrheic dermatitis (scaly, itchy skin), biotin appears to be ineffective based on available evidence.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body clears what it doesn't need through urine. Very rarely, high-dose biotin has been linked to mild diarrhea.

One isolated case report described a reaction when biotin was combined with another supplement and a prescription medication, but it's unclear what caused it and no similar cases have been reported since. Because this is a high-dose product, talk it over with your doctor before starting, especially if you're pregnant, breastfeeding, or taking other supplements.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for biotin with any medication types.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you have a biotin deficiency, this product is likely to help. For other uses like hair loss or skin conditions, the evidence doesn't support it.

The dose is high, so check with your own doctor or pharmacist before you start, particularly if you're pregnant, breastfeeding, or taking other supplements.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Extra Strength Biotin 2500 mcg, straight from the product label.

Brand Nature Made
Net contents 150 Softgel(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 270952
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Extra Strength Biotin 2500 mcg by Nature Made, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
150
IngredientAmount% DV
Biotin2500 mcg8333%

Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Water, Rapeseed Lecithin, Colors added

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

#1 pharmacist recommended

Value size

Seals/Symbols

USP Verified Dietary Supplement

Formulation

May help support healthy hair, skin and nails In those deficient in biotin

No synthetic dyes - colors derived from natural sources No artificial flavors Gluten free

USP has tested and verified ingredients, potency and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org Based on Pharmacy Times Survey of pharmacists recommending Letter Vitamin Supplements.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Adults, take 1 softgel daily with water and a meal.

Storage

Store tightly closed, in a cool, dry place, out of reach of children.

Precautions

Do not use if imprinted seal under cap is broken or missing.

Caution: Biotin may interfere with lab tests.

If you are taking medication or planning to undergo lab testing, consult your physician before use.

Store tightly closed, in a cool, dry place, out of reach of children.

See for yourself

Extra Strength Biotin 2500 mcg by Nature Made label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Extra Strength Biotin 2500 mcg by Nature Made

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container150 Amounts shown are per serving.

Biotin

No known
interactions
2500 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Water, Rapeseed Lecithin, Colors added. These complete the product’s ingredient list but are not active constituents.

Interaction report

Extra Strength Biotin 2500 mcg by Nature Made Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Extra Strength Biotin 2500 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Extra Strength Biotin 2500 mcg, from the product label.

Nature Made

See all Nature Made products
Name
Nature Made Nutritional Products
City
West Hills
State
CA
ZipCode
91309-9903
Phone Number
1-800-276-2878
Web Address
www.NatureMade.com
Pharmacist Counseling Corner

Extra Strength Biotin 2500 mcg by Nature Made: Common Questions

Does Extra Strength Biotin 2500 mcg by Nature Made interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Extra Strength Biotin 2500 mcg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Extra Strength Biotin 2500 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is biotin safe if I'm pregnant or breastfeeding?
Biotin is rated likely safe during pregnancy and lactation. That said, this is a high-dose supplement—much more than you'd get from food or a prenatal vitamin. Talk with your doctor before you start it, so they can weigh it for your situation.
What is biotin actually for?
Biotin is a B vitamin that helps your body convert food into energy and is important for hair, skin, and nail health. It's likely effective if you have a biotin deficiency, though that's uncommon.
Will biotin help my hair grow?
For alopecia areata (patchy hair loss), there isn't enough reliable evidence to say whether biotin helps. It's not established in the data we hold.
Can biotin cause side effects?
Biotin is generally well tolerated. Very rarely, high doses have been linked to mild diarrhea. One isolated case report linked it to a rare inflammatory reaction when taken alongside other supplements and a medication, but it's unclear what actually caused it, and no similar cases have been reported.
Is this product safe to take long-term?
Biotin is generally considered safe even at high doses because excess is removed through urine. That said, because this is a high-dose supplement, check in with your doctor before starting and during use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Extra Strength Biotin 2500 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Extra Strength Biotin 2500 mcg label
Go deeper

The Full Monographs Behind Extra Strength Biotin 2500 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Extra Strength Biotin 2500 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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