Interactions on record — worth a quick check against your medications. Based on 1 of 4 ingredients. Check your meds →
Dietary supplement

Fermented Chlorella with Chlorophyll Ingredients & Drug Interactions

by Dr. Mercola

Fermented Chlorella with Chlorophyll label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Fermented Chlorella with Chlorophyll against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Fermented Chlorella with Chlorophyll is a dietary supplement by Dr. Mercola with 4 active ingredients. Its ingredients are commonly taken for body and breath odor reduction, wound healing (topical), detoxification.Based on those ingredients, 337 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorophyll. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Fermented Chlorella with Chlorophyll by Dr. Mercola

Ask about any prescription or over-the-counter medication and we check it for interactions with Fermented Chlorella with Chlorophyll by Dr. Mercola — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Fermented Chlorella with Chlorophyll by Dr. Mercola

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Red Algae Blend” is a proprietary blend — the label gives one combined amount (30 mg) without saying how much of each component you get.
  • “Chlorella, Fermented” is listed as a grouped ingredient — the label gives one combined amount (970 mg) without saying how much of each component you get.

This product has 3 active ingredients: chlorophyll (the green pigment found in plants), Lithothamnion glaciale and Lithothamnion tophiforme (types of coralline algae rich in minerals), and a fermented chlorella blend. Chlorella is a freshwater microalga, and fermenting it may make it easier for your body to absorb.

There are no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Chlorophyll product and its label doesn't state a use — see Chlorophyll's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold for chlorophyll covers several uses — genital herpes, wound healing, shingles, skin cancer prevention, and pancreatitis — but every one is rated insufficient evidence to know whether it works. In other words, the research hasn't been strong enough to say either way.

We don't hold effectiveness data for the algae ingredients in this product.

The evidence, ingredient by ingredient Chlorophyll

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chlorophyll is generally well tolerated when used short-term, though solid safety research is limited. The most common side effect from taking chlorophyll by mouth is photosensitization — increased sensitivity to sun exposure that can cause exaggerated sunburn or skin reactions.

Rarely, oral chlorophyll has been linked to pseudoporphyria, a condition causing fragile, easily traumatized blisters on the hands. The safety data advises against this product during pregnancy.

Safety during breastfeeding isn't known, so avoid it unless your doctor says otherwise.

Side effects, ingredient by ingredient Chlorophyll

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chlorophyll.
  • The most serious interaction on file is rated Moderate.
  • For scale: 337 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any photosensitizing drugs you're on — those make your skin sun-sensitive, and chlorophyll may make that worse (Moderate severity). Also flag methotrexate if you take it, since chlorophyll may slow how your body clears it (Moderate severity).

Use the medication checker below to verify your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product might appeal to people interested in chlorophyll's theoretical health claims, but the evidence for those claims isn't established. If you take photosensitizing medications or methotrexate, check with your pharmacist before starting — the interaction risk is real.

The same goes if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fermented Chlorella with Chlorophyll, straight from the product label.

Brand Dr. Mercola
Barcode (UPC) 813006015851
Net contents 450 Tablet(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 327115
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fermented Chlorella with Chlorophyll by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Tablet(s)
Maximum serving Sizes:
5 Tablet(s)
Servings per container
90
UPC/BARCODE
813006015851
IngredientAmount% DV
Calories5 Calorie(s)--
Protein1 Gram(s)--
Chlorophyll13 mg--
Lithothamnion glaciale0 NP--
Red Algae Blend30 mg--
Lithothamnion tophiforme0 NP--
Chlorella, Fermented970 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Adults, as a dietary supplement, take five (5) tablets per serving. This product can be taken one to three times daily.

Precautions

Keep out of reach of children.

Do not use if safety seal is broken.

If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Chloropyll from algae Fermented nutrients

Seals/Symbols

Contents Certified NSF

FDA Statement of Identity

Dietary Supplement

Formulation

Product of South Korea

General Statements

Providing quality products since 2001.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Fermented Chlorella with Chlorophyll by Dr. Mercola label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Fermented Chlorella with Chlorophyll label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Fermented Chlorella with Chlorophyll by Dr. Mercola

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

1 Gram(s) per serving

Red Algae Blend

30 mg per serving
  • › Lithothamnion glaciale
  • › Lithothamnion tophiforme

Chlorella, Fermented

970 mg per serving Form: Green Algae, Fermented
Interaction report

Fermented Chlorella with Chlorophyll by Dr. Mercola Drug Interactions

Want to check YOUR meds against Fermented Chlorella with Chlorophyll?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
337Drugs
337 Moderate

Ingredients driving the most interactions

Chlorophyll 337

Individual Drug Interactions

The ingredients in Fermented Chlorella with Chlorophyll interact with 337 drugs. Click any drug to see the details.

1 of the 4 ingredients in Fermented Chlorella with Chlorophyll interact with drugs. Each result below shows which ingredient is responsible. Chlorophyll

Each ingredient & the kinds of drugs it affects

For each ingredient in Fermented Chlorella with Chlorophyll with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorophyll2 drug types · 337 drugs

Methotrexate (Trexall, Others)

Theoretically, chlorophyll may reduce the clearance of methotrexate.
In one case report, a 54-year-old male developed delayed clearance of intravenous high-dose methotrexate with concomitant use of chlorophyll. When chlorophyll was stopped 2 days prior to methotrexate treatment, methotrexate clearance was unaffected.

Likelihood Possible Evidence B
Photosensitizing Drugs

Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Chlorophyll has been reported to cause photosensitization. In two case reports, pseudoporphyria developed after oral intake of chlorophyll. Theoretically, concomitant use with other photosensitizing drugs may exacerbate this effect.

Likelihood Probable Evidence B
Chlorophyll full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Fermented Chlorella with Chlorophyll, from the product label.

Dr. Mercola

See all Dr. Mercola products
Name
NHP
Street Address
125 SW 3rd Place
City
Cape Coral
State
FL
ZipCode
33991
Phone Number
(877) 985-2696
Pharmacist Counseling Corner

Fermented Chlorella with Chlorophyll by Dr. Mercola: Common Questions

Does Fermented Chlorella with Chlorophyll by Dr. Mercola interact with any medications?
Yes. Based on its ingredients, Fermented Chlorella with Chlorophyll has a known interaction with 337 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fermented Chlorella with Chlorophyll contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against it during pregnancy. For breastfeeding, we don't have enough information, so talk with your doctor or pharmacist about what's right for you.
What are the side effects?
Photosensitization — increased sun sensitivity — is the most common side effect from chlorophyll by mouth. Rarely, it's been linked to pseudoporphyria, a condition causing fragile blisters on the hands. Overall, significant side effects are uncommon, but thorough safety research is limited.
Does this actually work for anything?
We hold evidence on chlorophyll for genital herpes, wound healing, shingles, skin cancer prevention, and pancreatitis, but every one is rated insufficient evidence — meaning the research isn't strong enough to say whether it works.
What's in this product?
The three active ingredients are chlorophyll, two types of coralline algae (Lithothamnion glaciale and Lithothamnion tophiforme), and a fermented chlorella blend. There are no inactive fillers listed.
Should I worry about sun exposure while taking this?
Yes — chlorophyll can cause photosensitization, which means your skin becomes more sensitive to sunlight. If you already take a medication that does that, chlorophyll may make the effect worse. Be extra careful with sun protection if you're on this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fermented Chlorella with Chlorophyll is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fermented Chlorella with Chlorophyll label
Go deeper

The Full Monographs Behind Fermented Chlorella with Chlorophyll’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chlorophyll

Interacts with 337 drugs

Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reducing body and fecal odor and as a topical...

Read the full Chlorophyll monograph →
Sources

Sources & How We Checked

Fermented Chlorella with Chlorophyll's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chlorophyll 5 references
  1. Mathews-Roth MM. Carotenoids in erythropoietic protoporphyria and other photosensitivity diseases. Ann N Y Acad Sci, 1993; 691:127-38. PubMed
  2. Belen'kii, G. B. and Krikun, B. L. [Treatment of herpes simplex and herpes zoster by chlorophyll preparations]. Sov.Med. 1971;34(1):151-152.
  3. Brooks SL, Sanders J, Seymour JF, Mellor JD. A case of delayed methotrexate clearance following administration of a complementary medication containing chlorophyll. J Oncol Pharm Pract. 2014 Jun;20(3):225-8. PubMed
  4. Rossi E, Borchard K, Cole JM. Pseudoporphyria following self-medication with chlorophyll. Australas J Dermatol. 2015 Feb;56(1):47-8. PubMed
  5. Zhao CY, Frew JW, Muhaidat J, et al. Chlorophyll-induced pseudoporphyria with ongoing photosensitivity after cessation - a case series of four patients. J Eur Acad Dermatol Venereol 2016;30(7):1239-42. PubMed

See these in context on the Chlorophyll monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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