Feverfew 0.7% Extract Powder Ingredients & Drug Interactions
by TerraVita Premium Collection
What is this page for?
First and foremost: checking Feverfew 0.7% Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Feverfew 0.7% Extract Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for migraine prevention, headache, fever (traditional).Based on those ingredients, 929 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Feverfew Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Feverfew 0.7% Extract Powder by TerraVita Premium Collection
Ask about any prescription or over-the-counter medication and we check it for interactions with Feverfew 0.7% Extract Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Feverfew 0.7% Extract Powder by TerraVita Premium Collection
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: feverfew extract in powder form, standardized to 0.7% strength. Feverfew is a plant traditionally used for headache relief.
The product has no inactive ingredients listed.
Does it work?
Couldn't assess
The evidence for feverfew's effectiveness is insufficient. The data we hold shows that tension headaches, psoriasis, rheumatoid arthritis, and a skin condition called prurigo nodularis have all been studied, but reliable evidence to confirm that feverfew actually works for any of these is not yet available.
How safe is it?
Well-documented data
Feverfew is generally well tolerated when taken short-term, though some people experience gastrointestinal side effects like nausea, diarrhea, constipation, abdominal pain, bloating, flatulence, and heartburn. Chewing fresh feverfew leaves is riskier than using prepared supplements and can cause mouth ulcers, tongue irritation, and swollen lips.
Skin rash may occur in sensitive people. One important note: if you stop taking feverfew after long-term use, you may experience "post-feverfew syndrome" — anxiety, headaches, and insomnia.
Feverfew is not recommended during pregnancy because it may stimulate the uterus and its safety isn't established. There isn't enough reliable safety information to use it while breastfeeding.
Meds to double-check
Moderate interaction found
If you take blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel), check with your doctor or pharmacist first — feverfew may raise your bleeding risk. Additionally, medications broken down by your liver through CYP2C19, CYP2D6, CYP1A2, CYP2C9, CYP2C8, or CYP3A4 pathways may build up to higher levels, though this hasn't been confirmed in humans yet.
Use the medication checker below to look up your exact prescriptions.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Feverfew may help with certain headaches, but the evidence isn't solid yet. The main concern is its potential to increase bleeding risk with blood thinners and other medications your liver processes.
If you take any prescription drugs or blood thinners, talk with your doctor or pharmacist before starting this product — they can check your specific medications against this supplement.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Feverfew 0.7% Extract Powder, straight from the product label.
| Brand | TerraVita Premium Collection |
|---|---|
| Barcode (UPC) | 064435201791 |
| Net contents | 4 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Jun 22, 2023 |
| DSLD ID | 290669 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Feverfew 0.7% Extract Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Feverfew Extract, Powder | 1000 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
A Dietary Supplement
Brand IP Statement(s)
Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Suggested/Recommended/Usage/Directions
Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.
General Statements
TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.
Please recycle!
FDA Disclaimer Statement
Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Feverfew 0.7% Extract Powder by TerraVita Premium Collection label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Feverfew 0.7% Extract Powder by TerraVita Premium Collection
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container113 Amounts shown are per serving.
Feverfew Extract, Powder
Interacts with929 drugs
Feverfew is a daisy-family herb best known for migraine prevention, where some studies suggest it may modestly lower how often migraines occur, though...
Feverfew Extract, Powder monograph & interactionsFeverfew 0.7% Extract Powder by TerraVita Premium Collection Drug Interactions
HelloPharmacist Interaction Report
Feverfew 0.7% Extract Powder by TerraVita Premium Collection interacts with several classes of medications through its effects on liver enzymes (cytochrome P450 proteins).
The most serious concern is with anticoagulant or antiplatelet drugs (blood thinners and clot-prevention medications) — feverfew may increase bleeding risk. Lab research suggests it can inhibit platelet aggregation (how blood cells stick together), and one case report documented vaginal bleeding in a patient taking high doses of feverfew for three months.
Read the full breakdown — every affected drug type, severity by severity
Feverfew may also affect how your body processes medications broken down by five different liver enzyme systems: CYP2C19, CYP2D6, CYP1A2, CYP2C9, CYP2C8, and CYP3A4. If your liver breaks down a drug more slowly than usual, the drug could build up to higher levels in your blood and cause unwanted effects.
These interactions are theoretical and have not yet been reported in humans, but they're documented in laboratory research.
Altogether, these interactions span 930 individual medications. Check the medication checker on this page with your exact prescriptions before starting this product, and let your doctor or pharmacist know you're considering it — especially if you take any blood thinners or medications processed by the liver.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Feverfew 0.7% Extract Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Feverfew 0.7% Extract Powder interact with 929 drugs. Click any drug to see the details.
1 of the 1 ingredient in Feverfew 0.7% Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Feverfew Extract, Powder
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Feverfew Extract, Powder + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, feverfew might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Feverfew Extract, Powder + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Feverfew Extract, Powder + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Feverfew Extract, Powder + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Feverfew Extract, Powder + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2C9.
Read the full Feverfew Extract, Powder + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Feverfew Extract, Powder + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, feverfew might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Feverfew Extract, Powder + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Feverfew Extract, Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Feverfew Extract, Powder + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Feverfew Extract, Powder + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Feverfew Extract, Powder + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Feverfew Extract, Powder + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Feverfew Extract, Powder + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Feverfew Extract, Powder + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Feverfew Extract, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Feverfew Extract, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Feverfew Extract, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Feverfew 0.7% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Feverfew Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Feverfew Extract, Powder + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Feverfew 0.7% Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Feverfew Extract, Powder
Anticoagulant/Antiplatelet Drugs
Theoretically, feverfew might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Laboratory research suggests that feverfew may inhibit platelet aggregation. Additionally, in one case report, a 36-year-old patient taking feverfew 2400 mg daily for 3 months experienced vaginal bleeding and a prolonged menstrual cycle, with a modest increase in partial thromboplastin time (PTT) and prothrombin time (PT).
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Laboratory research shows that feverfew might inhibit CYP1A2. So far, this interaction has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP2C19.
Laboratory research shows that feverfew might inhibit CYP2C19. So far, this interaction has not been reported in humans.
Cytochrome P450 2C8 (Cyp2C8) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP2C8.
Laboratory research shows that feverfew might inhibit CYP2C8. So far, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP2C9.
Laboratory research shows that feverfew might inhibit CYP2C9. So far, this interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Laboratory research shows that feverfew might inhibit CYP2D6. So far, this interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Laboratory research shows that feverfew might inhibit CYP3A4. So far, this interaction has not been reported in humans.
Brand information
Manufacturer and brand details for Feverfew 0.7% Extract Powder, from the product label.
TerraVita Premium Collection
See all TerraVita Premium Collection products- Name
- TerraVita Fine Whole Herbs
- City
- Brampton
- State
- Ontario
Feverfew 0.7% Extract Powder by TerraVita Premium Collection: Common Questions
Does Feverfew 0.7% Extract Powder by TerraVita Premium Collection interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is feverfew safe during pregnancy?
Is it safe to breastfeed while taking feverfew?
What side effects might I experience?
Can I stop taking feverfew whenever I want?
Does feverfew really work for headaches?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Feverfew 0.7% Extract Powder is safe with your meds?
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Feverfew 0.7% Extract Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Feverfew 0.7% Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
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The 18 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Feverfew 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Awang DVC. Prescribing therapeutic feverfew (Tancetum pathrnium (L.) Schultz Bip., syn. Chrysanthemumparthenium (L.) Bernh). Int Med 1998;1:11-3.
- Heptinstall S, Groenewegen WA, Spangenberg P, Loesche W. Extracts of feverfew may inhibit platelet behaviour via neutralization of sulphydryl groups. J Pharm Pharmacol 1987;39:459-65. PubMed
- Heptinstall S, White A, Williamson L, Mitchell JR. Extracts of feverfew inhibit granule secretion in blood platelets and polymorphonuclear leucocytes. Lancet 1985;1:1071-4. PubMed
- Makheja AN, Bailey JM. A platelet phospholipase inhibitor from the medicinal herb feverfew (Tanacetum parthenium). Prostaglandins Leukot Med 1982;8:653-60.
- Groenewegen WA, Heptinstall S. A comparison of the effects of an extract of feverfew and parthenolide, a component of feverfew, on human platelet activity in-vitro. J Pharm Pharmacol 1990;42:553-7. PubMed
- Heptinstall S, Groenewegen WA, Spangenberg P, Losche W. Inhibition of platelet behaviour by feverfew: a mechanism of action involving sulphydryl groups. Folia Haematol Int Mag Klin Morphol Blutforsch 1988;115:447-9.
- Biggs MJ, Johnson ES, Persaud NP, Ratcliffe DM. Platelet aggregation in patients using feverfew for migraine. Lancet 1982;2:776. PubMed
- Lamminpaa A, Estlander T, Jolanki R, Kanerva L. Occupational allergic contact dermatitis caused by decorative plants. Contact Dermatitis 1996;34:330-5. PubMed
- Johnson ES, Kadam NP, Hylands DM, Hylands PJ. Efficacy of feverfew as prophylactic treatment of migraine. Br Med J (Clin Res Ed) 1985;291:569-73. PubMed
- Pittler MH, Ernst E. Feverfew for preventing migraine. Cochrane Database Syst Rev 2004;(1):CD002286. PubMed
- Ernst E, Pittler MH. The efficacy and safety of feverfew (Tanacetum parthenium L.): an update of a systematic review. Public Health Nutr 2000;3:509-14.
- Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004;1 PubMed
- Sil'vestrov VP, Kinitin AV, and Chesnokova, IV. [Immunological and metabolic disorders and the means for their correction in patients with chronic bronchitis]. Ter.Arkh. 1991;63:7-11.
- Cady RK, Goldstein J, Nett R, et al. A double-blind placebo-controlled pilot study of sublingual feverfew and ginger (LipiGesic M) in the treatment of migraine. Headache 2011;51:1078-86.
- Jovanovic, M. and Poljacki, M. [Compositae dermatitis]. Med Pregl. 2003;56(1-2):43-49. PubMed
- Burry, J. N. Compositae dermatitis in South Australia: contact dermatitis from Chrysanthemum parthenium. Contact Dermatitis 1980;6(6):445.
- Alenzi KA, Alharbi FH, Tawhari FM, Fradees GS. Alteration of Coagulation Test Results and Vaginal Bleeding Associated With the Use of Feverfew (Tanacetum parthenium). J Med Cases 2021;12(1):9-12.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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