Feverfew Herb Powder Ingredients & Drug Interactions
by TerraVita Premium Collection
What is this page for?
First and foremost: checking Feverfew Herb Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Feverfew Herb Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for migraine prevention, headache, fever (traditional).Based on those ingredients, 929 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ferverfew, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Feverfew Herb Powder by TerraVita Premium Collection
Ask about any prescription or over-the-counter medication and we check it for interactions with Feverfew Herb Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Feverfew Herb Powder by TerraVita Premium Collection
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: feverfew powder. Feverfew is an herbal supplement traditionally used for headache relief and inflammation, though the evidence supporting those uses remains limited.
There are no inactive ingredients listed for this powder form.
Does it work?
Couldn't assess
The evidence for feverfew is insufficient to establish how well it works. Our data rates its use for tension headaches, prurigo nodularis (a skin condition), psoriasis, and rheumatoid arthritis as having insufficient reliable evidence.
That doesn't mean it doesn't help — it means studies haven't yet proven it does in a way we can rely on. If you're considering it for any of these conditions, talk it over with your doctor.
How safe is it?
Well-documented data
Feverfew powder is generally well tolerated over the short term. The most common side effects are gastrointestinal: abdominal pain, bloating, constipation, diarrhea, flatulence, heartburn, and nausea.
Skin rash may occur in sensitive people. Mouth irritation is less likely with commercial powder than with chewing fresh leaves, but it can still happen.
Avoid feverfew during pregnancy — it may stimulate the uterus and its safety in pregnancy is not established. There isn't enough reliable safety information to recommend it while breastfeeding.
Additionally, stopping feverfew after long-term use can trigger "post-feverfew syndrome," with symptoms like anxiety, headaches, and insomnia.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you take any blood thinners or antiplatelet drugs (warfarin, clopidogrel, aspirin at prescription doses). Also verify any other prescription medication you're on — feverfew may theoretically increase levels of drugs metabolized by your liver's CYP enzymes, including medications for heart rhythm, depression, pain, and seizures.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Feverfew powder may be worth considering if you've researched it for headaches or inflammation and want to try it, but the evidence of effectiveness is weak. The bigger issue is its potential to interact with numerous medications through liver enzyme inhibition and to raise bleeding risk with blood thinners.
Before you take it, check your medications against the interaction tool below and talk with your doctor or pharmacist, especially if you're on any prescription drugs.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Feverfew Herb Powder, straight from the product label.
| Brand | TerraVita Premium Collection |
|---|---|
| Barcode (UPC) | 064435108717 |
| Net contents | 1 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2023 |
| DSLD ID | 282045 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Feverfew Herb Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Ferverfew, Powder | 1000 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
A Dietary Supplement
Brand IP Statement(s)
Copyright 2004 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Suggested/Recommended/Usage/Directions
Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.
General Statements
TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.
Please recycle!
FDA Disclaimer Statement
Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Feverfew Herb Powder by TerraVita Premium Collection label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Feverfew Herb Powder by TerraVita Premium Collection
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container28 Amounts shown are per serving.
Ferverfew, Powder
Interacts with929 drugs
Feverfew is a daisy-family herb best known for migraine prevention, where some studies suggest it may modestly lower how often migraines occur, though...
Ferverfew, Powder monograph & interactionsFeverfew Herb Powder by TerraVita Premium Collection Drug Interactions
HelloPharmacist Interaction Report
Feverfew Herb Powder by TerraVita Premium Collection has documented interactions with multiple medications.
The main concern is through feverfew's potential to inhibit several liver enzymes (CYP2C19, CYP2D6, CYP1A2, CYP2C9, CYP3A4, and CYP2C8), which could theoretically raise blood levels of drugs broken down by those pathways. Laboratory research supports this effect, though it hasn't been reported in actual patients yet.
These are Moderate-severity interactions. Altogether, these interactions span 930 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Feverfew may also increase bleeding risk when taken alongside blood thinners or antiplatelet drugs (like warfarin or clopidogrel). Lab work suggests feverfew can slow clot formation, and one case report documented vaginal bleeding in a patient taking high-dose feverfew with anticoagulants.
Before you start this powder, run your medications through the interaction checker on this page. If you take any prescription drug — especially anything for heart rhythm, depression, pain, or blood clotting — check with your doctor or pharmacist first.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Feverfew Herb Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Feverfew Herb Powder interact with 929 drugs. Click any drug to see the details.
1 of the 1 ingredient in Feverfew Herb Powder interact with drugs. Each result below shows which ingredient is responsible. Ferverfew, Powder
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Ferverfew, Powder + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, feverfew might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Ferverfew, Powder + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Ferverfew, Powder + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Ferverfew, Powder + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Ferverfew, Powder + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2C9.
Read the full Ferverfew, Powder + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Ferverfew, Powder + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, feverfew might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Ferverfew, Powder + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Ferverfew, Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Ferverfew, Powder + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Ferverfew, Powder + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Ferverfew, Powder + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Ferverfew, Powder + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Ferverfew, Powder + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Ferverfew, Powder + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Ferverfew, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Read the full Ferverfew, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Read the full Ferverfew, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Feverfew Herb Powder — through 1 ingredient. Tap an ingredient for the detail:
Ferverfew, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Read the full Ferverfew, Powder + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Feverfew Herb Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Ferverfew, Powder
Anticoagulant/Antiplatelet Drugs
Theoretically, feverfew might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Laboratory research suggests that feverfew may inhibit platelet aggregation. Additionally, in one case report, a 36-year-old patient taking feverfew 2400 mg daily for 3 months experienced vaginal bleeding and a prolonged menstrual cycle, with a modest increase in partial thromboplastin time (PTT) and prothrombin time (PT).
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Laboratory research shows that feverfew might inhibit CYP1A2. So far, this interaction has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP2C19.
Laboratory research shows that feverfew might inhibit CYP2C19. So far, this interaction has not been reported in humans.
Cytochrome P450 2C8 (Cyp2C8) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP2C8.
Laboratory research shows that feverfew might inhibit CYP2C8. So far, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP2C9.
Laboratory research shows that feverfew might inhibit CYP2C9. So far, this interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Laboratory research shows that feverfew might inhibit CYP2D6. So far, this interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Laboratory research shows that feverfew might inhibit CYP3A4. So far, this interaction has not been reported in humans.
Brand information
Manufacturer and brand details for Feverfew Herb Powder, from the product label.
TerraVita Premium Collection
See all TerraVita Premium Collection products- Name
- TerraVita Fine Whole Herbs
- City
- Brampton
- State
- Ontario
Feverfew Herb Powder by TerraVita Premium Collection: Common Questions
Does Feverfew Herb Powder by TerraVita Premium Collection interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is feverfew safe during pregnancy?
Is it safe while breastfeeding?
What side effects might I get?
Does feverfew actually work for headaches?
Can I take this if I'm on a blood thinner like warfarin?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Feverfew Herb Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Feverfew Herb Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Feverfew Herb Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 18 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Feverfew 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Awang DVC. Prescribing therapeutic feverfew (Tancetum pathrnium (L.) Schultz Bip., syn. Chrysanthemumparthenium (L.) Bernh). Int Med 1998;1:11-3.
- Heptinstall S, Groenewegen WA, Spangenberg P, Loesche W. Extracts of feverfew may inhibit platelet behaviour via neutralization of sulphydryl groups. J Pharm Pharmacol 1987;39:459-65. PubMed
- Heptinstall S, White A, Williamson L, Mitchell JR. Extracts of feverfew inhibit granule secretion in blood platelets and polymorphonuclear leucocytes. Lancet 1985;1:1071-4. PubMed
- Makheja AN, Bailey JM. A platelet phospholipase inhibitor from the medicinal herb feverfew (Tanacetum parthenium). Prostaglandins Leukot Med 1982;8:653-60.
- Groenewegen WA, Heptinstall S. A comparison of the effects of an extract of feverfew and parthenolide, a component of feverfew, on human platelet activity in-vitro. J Pharm Pharmacol 1990;42:553-7. PubMed
- Heptinstall S, Groenewegen WA, Spangenberg P, Losche W. Inhibition of platelet behaviour by feverfew: a mechanism of action involving sulphydryl groups. Folia Haematol Int Mag Klin Morphol Blutforsch 1988;115:447-9.
- Biggs MJ, Johnson ES, Persaud NP, Ratcliffe DM. Platelet aggregation in patients using feverfew for migraine. Lancet 1982;2:776. PubMed
- Lamminpaa A, Estlander T, Jolanki R, Kanerva L. Occupational allergic contact dermatitis caused by decorative plants. Contact Dermatitis 1996;34:330-5. PubMed
- Johnson ES, Kadam NP, Hylands DM, Hylands PJ. Efficacy of feverfew as prophylactic treatment of migraine. Br Med J (Clin Res Ed) 1985;291:569-73. PubMed
- Pittler MH, Ernst E. Feverfew for preventing migraine. Cochrane Database Syst Rev 2004;(1):CD002286. PubMed
- Ernst E, Pittler MH. The efficacy and safety of feverfew (Tanacetum parthenium L.): an update of a systematic review. Public Health Nutr 2000;3:509-14.
- Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004;1 PubMed
- Sil'vestrov VP, Kinitin AV, and Chesnokova, IV. [Immunological and metabolic disorders and the means for their correction in patients with chronic bronchitis]. Ter.Arkh. 1991;63:7-11.
- Cady RK, Goldstein J, Nett R, et al. A double-blind placebo-controlled pilot study of sublingual feverfew and ginger (LipiGesic M) in the treatment of migraine. Headache 2011;51:1078-86.
- Jovanovic, M. and Poljacki, M. [Compositae dermatitis]. Med Pregl. 2003;56(1-2):43-49. PubMed
- Burry, J. N. Compositae dermatitis in South Australia: contact dermatitis from Chrysanthemum parthenium. Contact Dermatitis 1980;6(6):445.
- Alenzi KA, Alharbi FH, Tawhari FM, Fradees GS. Alteration of Coagulation Test Results and Vaginal Bleeding Associated With the Use of Feverfew (Tanacetum parthenium). J Med Cases 2021;12(1):9-12.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC