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Dietary supplement

FlashArrest Ingredients & Drug Interactions

by XYMOGEN

FlashArrest label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking FlashArrest against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

FlashArrest is a dietary supplement by XYMOGEN with 2 active ingredients. Its ingredients are commonly taken for sleep problems and insomnia, anxiety and restlessness, menopausal symptoms.Based on those ingredients, 863 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hops Flower Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against FlashArrest by XYMOGEN

Ask about any prescription or over-the-counter medication and we check it for interactions with FlashArrest by XYMOGEN — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of FlashArrest by XYMOGEN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “FlashArrest Proprietary Blend” is a proprietary blend — the label gives one combined amount (193 mg) without saying how much of each component you get.

FlashArrest contains two active ingredients. Hops flower extract is included for its traditional use in formulas addressing sleep, anxiety, and digestive comfort, though reliable evidence for these purposes is limited.

Norway spruce knotwood extract rounds out the blend, also with limited established evidence in the data we hold. The capsule itself is made from microcrystalline cellulose, hypromellose, water, stearic acid, magnesium stearate, and silica — standard inactive ingredients that help deliver and stabilize the formula.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support healthy aromatase function.
  • We looked for evidence on: Menopausal symptoms, Hormonal balance, Estrogen metabolism.
  • The closest evidence on file: Hops is rated "Insufficient Reliable Evidence To Rate" for Menopausal symptoms (Natural Medicines).

The evidence we hold doesn't establish that either ingredient in this product is reliable for its traditional uses. Hops has insufficient evidence for age-related cognitive decline, sexual dysfunction, anxiety, ADHD, indigestion, and insomnia.

Norway spruce knotwood extract similarly lacks established evidence for respiratory infections or acute pain. If you're considering this product for a specific condition, talk it over with your doctor or pharmacist about what the science actually supports.

The evidence, ingredient by ingredient Hops Norway Spruce

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hops is generally well tolerated short-term but may cause drowsiness — so don't drive or use machinery until you know how it affects you. Long-term safety hasn't been well studied.

The safety data advises against hops in pregnancy and while breastfeeding due to insufficient information. Norway spruce knotwood is also not recommended in pregnancy or while breastfeeding, and while it's tolerated in food amounts, the concentrated essential oil can irritate skin and airways — this product is a standardized extract, not the oil, but that's worth knowing.

Side effects, ingredient by ingredient Hops Norway Spruce

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Hops.
  • The most serious interaction on file is rated Moderate.
  • For scale: 864 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking FlashArrest, check with your doctor or pharmacist if you take CNS depressants (sedatives, sleep aids, anti-anxiety medications) — hops can add to their drowsy effects. If you're on estrogens (birth control pills or hormone replacement therapy), confirm it's okay, since hops may theoretically interfere.

Also double-check if you take medications your liver processes (CYP1A2 or CYP3A4 substrates), though real-world problems are less certain.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

FlashArrest may be worth considering if you're looking for a traditional sleep or relaxation support formula, but the evidence for its effectiveness is limited. If you take sedatives, birth control pills, hormone replacement therapy, or medications processed by your liver, check with your doctor or pharmacist before starting — hops can interact with these.

Pregnant women and those breastfeeding should avoid it. Talk it over with your own healthcare provider to see if it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about FlashArrest, straight from the product label.

Brand XYMOGEN
Barcode (UPC) 871149004088
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 303690
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), No Allergies, Menopause, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for FlashArrest by XYMOGEN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
871149004088
IngredientAmount% DV
FlashArrest Proprietary Blend193 mg--
Hops Flower Extract0 NP--
Norway Spruce Knotwood Extract0 NP--

Other ingredients: Microcrystalline Cellulose, Hypromellose, Water, Stearic Acid, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

DIRECTIONS: Take one to two capsules daily, or use as directed by your healthcare professional.

Precautions

Consult your healthcare professional prior to use.

Individuals taking medication should discuss potential interactions with their healthcare professional.

Do not use if tamper seal is damaged.

STORAGE: Keep closed in a cool, dry place out of reach of children.

Formula

FlashArrest delivers a unique, proprietary blend of 8-prenylnaringenin (8-PN) from hops and plant-lignin extract at clinically relevant levels. Research suggests lignans and 8-PN can support the body’s natural process of healthy aromatase activity and exert phytoestrogen (e.g., enterolactone) and antioxidant activity.

Targeting Estrogen Activity for Men and Women

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

STORAGE: Keep closed in a cool, dry place out of reach of children.

Formulation

FORMULATED TO EXCLUDE: Wheat, gluten, corn, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, sesame, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.

This all-natural formula may support cardiovascular, bone, breast, and prostate health and help relieve normal menopausal discomforts.

Brand IP Statement(s)

Copyright 2022 XYMOGEN

Xymogen Exclusive professional formulas

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

ePV (ePedigree Verification)

Vegetarian caps

GMP compliant third-party verified

General Statements

Scan to learn more! This package is completely recyclable

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See for yourself

FlashArrest by XYMOGEN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

FlashArrest label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in FlashArrest by XYMOGEN

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

FlashArrest Proprietary Blend

193 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Water, Stearic Acid, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

FlashArrest by XYMOGEN Drug Interactions

Want to check YOUR meds against FlashArrest?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
863Drugs
289 Moderate 574 Minor

Ingredients driving the most interactions

Hops Flower Extract 863

Individual Drug Interactions

The ingredients in FlashArrest interact with 863 drugs. Click any drug to see the details.

1 of the 2 ingredients in FlashArrest interact with drugs. Each result below shows which ingredient is responsible. Hops Flower Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in FlashArrest with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Hops Flower Extract4 drug types · 863 drugs

Cns Depressants

Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Some animal research shows that hops has sedative effects.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of large amounts of hops might interfere with hormone replacement therapy due to competition for estrogen receptors.
In vitro research suggests that certain hops constituents can competitively bind to estrogen receptors. However, most hops extracts contain very small amounts of these constituents.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
In vitro research suggests that flavonoid constituents of hops inhibit CYP1A2 enzyme activity. However, a pharmacokinetic study in healthy postmenopausal patients shows that taking a standardized extract of spent hops containing prenylated phenols, as 59.5 mg twice daily for 2 weeks, does not affect levels of caffeine, a CYP1A2 probe substrate.

Likelihood Unlikely Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Animal research suggests that specific constituents of hops, called lupulones, can induce hepatic CYP3A4 enzyme activity. However, a pharmacokinetic study in healthy postmenopausal patients with normal metabolism shows that taking a standardized extract of spent hops containing prenylated phenols, as 59.5 mg twice daily for 2 weeks, decreases the concentration of alprazolam, a CYP3A4 probe substrate, by 7.6%. This reduction is unlikely to be clinically relevant.

Likelihood Possible Evidence D
Hops Flower Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for FlashArrest, from the product label.

XYMOGEN

See all XYMOGEN products
Name
XYMOGEN Exclusive Professional Formulas
Street Address
6900 Kingspointe Pkwy.
City
Orlando
State
FL
ZipCode
32819
Phone Number
800-647-6100
Web Address
www.xymogen.com
Pharmacist Counseling Corner

FlashArrest by XYMOGEN: Common Questions

Does FlashArrest by XYMOGEN interact with any medications?
Yes. Based on its ingredients, FlashArrest has a known interaction with 863 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
FlashArrest contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will FlashArrest make me drowsy?
Hops can cause drowsiness, especially short-term. The data doesn't tell us how often this happens or how strong it is, but don't drive or use machinery until you see how it affects you personally.
Can I take this if I'm on birth control or hormone replacement?
Hops theoretically could interfere with estrogen-based hormones, though most hops extracts contain only small amounts of the active constituents. Talk with your doctor or pharmacist before combining them — they know your full picture and can advise you on whether it's safe for you.
Is FlashArrest safe during pregnancy?
No — there isn't enough safety information, so the data advises against it in pregnancy. If you're pregnant or planning to be, talk with your doctor before taking any supplement.
Can I use FlashArrest while breastfeeding?
The safety data advises against it while breastfeeding because there isn't enough information on how it might affect your baby. Check with your doctor or pharmacist for personalized advice.
Does FlashArrest actually work for sleep or anxiety?
The evidence we hold is insufficient to say it's reliable for sleep, anxiety, or the other conditions it's traditionally used for. If you're dealing with sleep or anxiety issues, your doctor can discuss what treatments have real evidence behind them.
What are the inactive ingredients, and are there fillers?
The inactive ingredients are microcrystalline cellulose, hypromellose, water, stearic acid, magnesium stearate, and silica — standard capsule materials and stabilizers. These help deliver the active ingredients; they're not "fillers" in the sense of being unnecessary, but standard pharmaceutical practice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

FlashArrest label
Go deeper

The Full Monographs Behind FlashArrest’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hops

Interacts with 863 drugs

Hops are most often used for sleep and mild anxiety, frequently combined with valerian, but the human evidence is limited and not very strong. They are generally well tolerated when used sho...

Read the full Hops monograph → Herb & supplement monograph

Norway Spruce

Norway Spruce is an evergreen tree whose needles, shoots, bark, and essential oil have long been used in traditional medicine for coughs, congestion, and sore muscles. Solid human research i...

Read the full Norway Spruce monograph →
Sources

Sources & How We Checked

FlashArrest's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hops 15 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Zava DT, Dollbaum CM, Blen M. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med 1998;217:369-78. PubMed
  4. Milligan SR, Kalita JC, Heyerick A, et al. Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer. J Clin Endocrinol Metab 1999;84:2249-52.. PubMed
  5. Milligan SR, Kalita JC, Pocock V, et al. The endocrine activities of 8-prenylnaringenin and related hop (Humulus lupulus L.) flavonoids. J Clin Endocrinol Metab 2000;85:4912-5.. DOI
  6. Henderson MC, Miranda CL, Stevens JF, et al. In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus. Xenobiotica 2000;30:235-51.. PubMed
  7. Mannering, G. J., Shoeman, J. A., and Deloria, L. B. Identification of the antibiotic hops component, colupulone, as an inducer of hepatic cytochrome P-4503A in the mouse. Drug Metab Dispos 1992;20(2):142-147. DOI
  8. Skorska, C., Mackiewicz, B., Gora, A., Golec, M., and Dutkiewicz, J. Health effects of inhalation exposure to organic dust in hops farmers. Ann.Univ Mariae.Curie Sklodowska [Med] 2003;58(1):459-465.
  9. Schiller, H., Forster, A., Vonhoff, C., Hegger, M., Biller, A., and Winterhoff, H. Sedating effects of Humulus lupulus L. extracts. Phytomedicine. 2006;13(8):535-541. PubMed
  10. van Hunsel, F. P. and Kampschoer, P. [Postmenopausal bleeding and dietary supplements: a possible causal relationship with hop- and soy-containing preparations]. Ned.Tijdschr.Geneeskd. 2012;156(41):A5095.
  11. Fenselau, C. and Talalay, P. Is oestrogenic activity present in hops? Food Cosmet.Toxicol. 1973;11(4):597-602. PubMed
  12. Godnic-Cvar, J., Zuskin, E., Mustajbegovic, J., Schachter, E. N., Kanceljak, B., Macan, J., Ilic, Z., and Ebling, Z. Respiratory and immunological findings in brewery workers. Am J Ind Med 1999;35(1):68-75. DOI
  13. Lee KM, Jung JS, Song DK, and et al. Effects of Humulus lupulus extract on the central nervous system in mice. Planta Med 1993;59(Suppl):A691.
  14. Assessment report on Humulus lupulus L., flos. European Medicines Agency, 2014. Available at: https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-humulus-lupulus-l-flos_en.pdf. Accessed September 29, 2021.
  15. van Breemen RB, Chen L, Tonsing-Carter A, et al. Pharmacokinetic Interactions of a Hop Dietary Supplement with Drug Metabolism in Perimenopausal and Postmenopausal Women. J Agric Food Chem. 2020;68(18):5212-5220. PubMed

See these in context on the Hops monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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