Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Flavo-C Ingredients & Drug Interactions

by NF NutriPlex Formulas

Flavo-C label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Flavo-C against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Flavo-C is a dietary supplement by NF NutriPlex Formulas with 5 active ingredients. Its ingredients are commonly taken for eye and vision health, antioxidant support, diarrhea and digestive upset.Based on those ingredients, 1,018 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Echinacea purpurea, Bilberry, Acerola Cherry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Flavo-C by NF NutriPlex Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Flavo-C by NF NutriPlex Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Flavo-C by NF NutriPlex Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,460 mg) without saying how much of each component you get.

Flavo-C contains five active ingredients. Bilberry, acerola cherry, echinacea purpurea, wild pansy, and horse chestnut are each included to support different aspects of health — bilberry for eye function, acerola as a source of vitamin C, echinacea for immune support, wild pansy for respiratory and skin health, and horse chestnut for circulation and venous support.

The product also contains three inactive ingredients (cellulose, acacia, and potato starch) that serve as fillers and binders to hold the tablet together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Whole food vitamin C and bioflavonoid support.
  • We looked for evidence on: Vitamin C deficiency, Common cold, Influenza, Upper respiratory tract infection (URTI), Atopic dermatitis (eczema), Chronic venous insufficiency (CVI) — and 4 related terms.
  • The strongest evidence on file: Acerola is rated "Possibly Effective" for Vitamin C deficiency (Natural Medicines).
  • Also on file: Horse Chestnut is rated "Possibly Effective" for Chronic venous insufficiency (CVI).
  • Also on file: Heart's Ease is rated "Insufficient Reliable Evidence To Rate" for Atopic dermatitis (eczema).

The evidence for what this formula actually does is mixed and limited. Bilberry is rated possibly ineffective for night vision, while evidence is insufficient to rate it for age-related cognitive decline, macular degeneration, atherosclerosis, high cholesterol, or venous insufficiency.

Acerola cherry is possibly effective for vitamin C deficiency but has insufficient evidence for atherosclerosis, common cold, or diarrhea. Echinacea purpurea shows insufficient evidence for anxiety, athletic performance, ADHD, burns, chronic fatigue, or migraine.

Wild pansy's evidence is insufficient for COPD or eczema. Horse chestnut is possibly effective for chronic venous insufficiency but has insufficient evidence for hemorrhoids, irritable bowel syndrome, or kidney stones.

Overall, reliable evidence supporting the product's specific benefits is not well established in the data we hold.

The evidence, ingredient by ingredient Bilberry Acerola Echinacea Heart's Ease Horse Chestnut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bilberry fruit is generally well tolerated when eaten as food, but concentrated supplements have limited long-term safety data — the safety notes recommend avoiding supplement doses due to insufficient information. Common side effects include dark stools, flatulence, and gastrointestinal discomfort; in one small trial, 33% of participants reported mild-to-moderate gas, and dark discoloration of stools and tongue may occur.

Acerola is generally safe in food amounts as directed on labels; one rare case reported an allergic reaction in someone with latex sensitivity, and very high doses of vitamin C (the acerola component) above 2,000 mg daily can cause diarrhea and GI upset. Echinacea is well tolerated short-term but may trigger allergic reactions in people sensitive to ragweed and related plants; rare cases of hepatitis have been reported, and allergic reactions including severe ones like anaphylaxis are possible, especially in atopic individuals.

Echinacea is rated possibly safe in pregnancy but has no lactation data on file. Wild pansy is generally well tolerated but has caused hemolysis (destruction of red blood cells) in one infant with G6PD deficiency; it should be avoided in pregnancy and breastfeeding due to insufficient safety information.

Horse chestnut seed extract (with the toxic part removed) is reasonably tolerated and causes dizziness, GI upset, headache, or itching in some users; however, the raw plant is toxic. Horse chestnut is rated unsafe in pregnancy and lactation.

Overall, while these ingredients are generally well tolerated, concentrated supplements carry safety unknowns, and several pose real risks in specific populations or with certain conditions.

Side effects, ingredient by ingredient Bilberry Acerola Echinacea Heart's Ease Horse Chestnut

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Bilberry, Acerola, Echinacea, Horse Chestnut.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; cancer treatments; diabetes medications.
  • For scale: 1,019 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Flavo-C, double-check with your doctor or pharmacist if you're on any of these: blood thinners or antiplatelet drugs (from bilberry and horse chestnut at Moderate severity), diabetes medications (bilberry, Moderate), drugs processed by the liver enzyme CYP1A2 such as caffeine or certain other medications (echinacea, Moderate), immunosuppressants (echinacea, Moderate), estrogens including birth control or hormone therapy (acerola, Minor), or cancer medications including erlotinib or etoposide (bilberry and echinacea, Moderate). If you're on any medications at all, use the checker below to see your exact drugs before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Flavo-C is a multi-ingredient botanical blend that may appeal to you if you're interested in natural support for vision, immunity, circulation, or skin health — but reliable evidence that it actually works for these purposes is limited or absent. If you take any blood thinners, diabetes medications, immunosuppressants, or drugs processed by the liver, or if you have a history of ragweed allergy, G6PD deficiency, or are pregnant or breastfeeding, talk with your doctor or pharmacist before starting this product.

The ingredient interactions and safety gaps mean this isn't a "grab and go" choice — clear it with your own healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Flavo-C, straight from the product label.

Brand NF NutriPlex Formulas
Barcode (UPC) 670541998359
Net contents 125 Tablet(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 304456
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Flavo-C by NF NutriPlex Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Tablet(s)
Maximum serving Sizes:
6 Tablet(s)
Servings per container
31
UPC/BARCODE
670541998359
IngredientAmount% DV
Proprietary Blend1460 mg--
Bilberry0 NP--
Acerola Cherry0 NP--
Echinacea purpurea0 NP--
Wild Pansy0 NP--
Horse Chestnut0 NP--

Other ingredients: Cellulose, Acacia, Potato Starch

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Whole food vitamin C & bioflavonoids

FDA Statement of Identity

A 100% Whole Food Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested usage: As a dietary supplement, adults take 4-6 tablets daily or as directed by healthcare practitioner.

Precautions

Pregnant and lactating women, as well as persons under medical care or on prescription drugs should always consult with physician before consuming this or any other supplement.

Keep away from children.

Tamper resistant package.

Storage

Store in a cool, dry place.

Formulation

Contains no yeast, soy, milk/dairy, corn, artificial flavors, sterilized substances, genetically engineered ingredients, artificial coloring or preservatives.

Contains organic & wildcrafted ingredients.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Flavo-C by NF NutriPlex Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Flavo-C label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Flavo-C by NF NutriPlex Formulas

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Tablet(s) Dosage formTablet Or Pill Servings per container31 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1460 mg per serving

Other (inactive) ingredients: Cellulose, Acacia, Potato Starch. These complete the product’s ingredient list but are not active constituents.

Interaction report

Flavo-C by NF NutriPlex Formulas Drug Interactions

Want to check YOUR meds against Flavo-C?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,018Drugs
1,003 Moderate 15 Minor

Ingredients driving the most interactions

Echinacea purpurea 816
Bilberry 275
Acerola Cherry 128
Horse Chestnut 122

Individual Drug Interactions

The ingredients in Flavo-C interact with 1,018 drugs. Click any drug to see the details.

4 of the 5 ingredients in Flavo-C interact with drugs. Each result below shows which ingredient is responsible. Echinacea purpurea Bilberry Acerola Cherry Horse Chestnut

Each ingredient & the kinds of drugs it affects

For each ingredient in Flavo-C with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Echinacea purpurea12 drug types · 816 drugs

Caffeine

Echinacea can increase plasma levels of caffeine by inhibiting its metabolism.
Echinacea seems to increase plasma concentrations of caffeine by around 30%. This is likely due to inhibition of cytochrome P450 1A2 (CYP1A2) by echinacea.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Echinacea appears to inhibit CYP1A2 enzymes in humans. Additionally, echinacea seems to increase plasma concentrations of caffeine, a CYP1A2 substrate, by around 30%. Theoretically, echinacea might increase levels of other drugs metabolized by CYP1A2.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4. This may increase or decrease levels of drugs metabolized by CYP3A4.
Several clinical trials have shown that taking echinacea for up to one month does not significantly affect the metabolism of various CYP3A4 substrates, including midazolam, docetaxel, etravirine, lopinavir-ritonavir, and darunavir-ritonavir. However, other clinical research shows that echinacea may increase the clearance of midazolam, suggesting that echinacea might induce CYP3A4. The discrepancy is thought to be due to differing effects of echinacea on intestinal versus hepatic CYP3A4 enzymes. Echinacea appears to induce hepatic CYP3A4 but inhibit intestinal CYP3A4. In some cases, these effects might cancel each other out, but in others, drug levels may be increased or decreased depending on the level of effect at hepatic and intestinal sites. The effect of echinacea on CYP3A4 activity may differ depending on the CYP3A4 substrate.

Likelihood Possible Evidence B
Etoposide (Vepesid)

Echinacea may increase levels of etoposide.
In one report, concomitant use of etoposide and echinacea was associated with more severe thrombocytopenia than the use of etoposide alone, suggesting inhibition of etoposide metabolism. Etoposide is a cytochrome P450 3A4 (CYP3A4) substrate. Echinacea has variable effects on CYP3A4, but some studies have reported inhibition of the enzyme.

Likelihood Possible Evidence D
Immunosuppressants

Echinacea has immunostimulant activity which may interfere with immunosuppressant therapy.
Theoretically, echinacea may interfere with immunosuppressant therapy because of its immunostimulant activity.

Likelihood Possible Evidence B
Darunavir (Prezista)

Theoretically, echinacea may interfere with the metabolism of darunavir; however, a small clinical study found no effect.
Darunavir is metabolized by cytochrome P450 3A4 (CYP3A4) and is administered with the CYP3A4 inhibitor ritonavir to increase its plasma concentrations. Echinacea has variable effects on CYP3A4, but administration of an E. purpurea root extract (Arkocapsulas Echinacea, Arkopharma) 500 mg four times daily for 14 days did not affect darunavir/ritonavir pharmacokinetics in 15 HIV-infected patients.

Likelihood Unlikely Evidence B
Dayquil Severe

Echinacea is reported to have varying effects on a number of Cytochrome P450 metabolizing enzymes in the liver, including CYP1A2 and CYP3A4, which play a role in acetaminophen and dextromethorphan metabolism (both contained in DayQuil Severe), respectively. Studies have reported both enzyme inhibition and induction, making it difficult to predict clinically significant drug interactions with reliability. Specific drug interaction studies reporting definitive results are rare, and potential drug interactions involving echinacea should likely be taken on a case-by-case basis. Based on what we know about how acetaminophen and dextromethorphan are metabolized, the risk of a clinically significant interaction between echinacea and DayQuil Severe is low.

Likelihood Unlikely Evidence A
Docetaxel (Taxotere)

Theoretically, echinacea may interfere with the metabolism of docetaxel; however, a small clinical study found no effect.
Docetaxel is metabolized by cytochrome P450 3A4 (CYP3A4). Echinacea has variable effects on CYP3A4, but taking E. purpurea whole plant extract (Echinaforce, A. Vogel Biopharma AG) 20 drops three times daily for 2 weeks did not alter the pharmacokinetics of docetaxel in one clinical study.

Likelihood Unlikely Evidence B
Etravirine (Intelence)

Theoretically, echinacea may interfere with the metabolism of etravirine; however, a small clinical study found no effect.
Etravirine is metabolized by cytochrome P450 3A4 (CYP3A4). Echinacea has variable effects on CYP3A4, but taking E. purpurea root extract (Arkocapsulas Echinacea, Arkopharma) 500 mg three times daily for 14 days did not alter the pharmacokinetics of etravirine in HIV-infected patients.

Likelihood Unlikely Evidence B
Lopinavir/Ritonavir (Kaletra)

Theoretically, echinacea may interfere with the metabolism of lopinavir; however, a small clinical study found no effect.
Lopinavir is metabolized by cytochrome P450 3A4 (CYP3A4) and is administered with the CYP3A4 inhibitor ritonavir to increase its plasma concentrations. Echinacea has variable effects on CYP3A4, but taking E. purpurea (Echinamide, Natural Factors Nutritional Products, Inc.) 500 mg three times daily for 14 days did not alter the pharmacokinetics of lopinavir/ritonavir in healthy volunteers.

Likelihood Unlikely Evidence B
Midazolam (Versed)

Theoretically, echinacea may increase the metabolism of intravenous midazolam.
Echinacea induces hepatic CYP3A4 and might decrease plasma levels of midazolam by about 20%, reducing the effectiveness of intravenous midazolam. Echinacea also appears to inhibit intestinal CYP3A4, which could theoretically increase the bioavailability of oral midazolam. This may cancel out the decrease in availability caused by induction of hepatic CYP3A4, such that overall plasma levels after oral administration of midazolam are not affected by echinacea.

Likelihood Possible Evidence B
Warfarin (Coumadin)

Echinacea seems to increase the clearance of warfarin, although the effect may not be clinically significant.
Preliminary clinical research in healthy male volunteers suggests that taking echinacea increases the clearance of the active S-isomer of warfarin after a single dose of warfarin, but there was not a clinically significant effect on the INR.

Likelihood Possible Evidence B
Echinacea purpurea full monograph & interactions

Bilberry4 drug types · 275 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Erlotinib (Tarceva)

Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Bilberry full monograph & interactions

Acerola Cherry6 drug types · 128 drugs

Alkylating Agents

Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Acerola contains vitamin C, an antioxidant. There is concern that antioxidants might reduce the activity of chemotherapy drugs that generate free radicals, such as alkylating agents. In contrast, other researchers theorize that antioxidants might make alkylating chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Antitumor Antibiotics

Theoretically, the antioxidant effects of acerola might reduce the effectiveness of antitumor antibiotics.
Acerola contains vitamin C, an antioxidant. There is concern that antioxidants might reduce the activity of chemotherapy drugs that generate free radicals, such as antitumor antibiotics. In contrast, other researchers theorize that antioxidants might make antitumor antibiotic chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on antitumor antibiotic chemotherapy.

Likelihood Possible Evidence D
Aluminum

Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Acerola contains vitamin C. It is thought that vitamin C chelates aluminum, keeping it in solution and available for absorption. In people with normal renal function, urinary excretion of aluminum likely increases, making aluminum retention and toxicity unlikely. However, patients with renal failure who take aluminum-containing compounds, such as phosphate binders, should avoid acerola in doses that provide more vitamin C than the recommended dietary allowances.

Likelihood Possible Evidence D
Aspirin

Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Acerola contains vitamin C. It has been suggested that acidification of the urine by vitamin C can decrease the urinary excretion of salicylates, increasing plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion. The vitamin C content of acerola is typically about 2000 mg per 100 grams. Thus, a clinically significant interaction between acerola and aspirin is unlikely.

Likelihood Unlikely Evidence B
Estrogens

Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Acerola contains vitamin C. Increases in plasma estrogen levels of up to 55% have occurred under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. However, increases in plasma estrogen levels may occur when women who are deficient in vitamin C take supplements.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, acerola might reduce the effectiveness of warfarin; however, its vitamin C content is likely too low to produce clinically significant effects.
Acerola contains vitamin C. High doses of vitamin C may reduce the response to warfarin, possibly by causing diarrhea and reducing warfarin absorption. This occurred in two people who took up to 16 grams daily of vitamin C, and resulted in decreased prothrombin time. Lower doses of 5-10 grams daily of vitamin C can also reduce warfarin absorption, but this does not seem to be clinically significant. The vitamin C content of acerola is typically about 2000 mg per 100 grams. Thus, a clinically significant interaction between acerola and warfarin is unlikely.

Likelihood Unlikely Evidence D
Acerola Cherry full monograph & interactions

Horse Chestnut1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Horse chestnut may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Horse chestnut contains the constituent esculin which has been shown to have antithrombotic effects. Therefore, horse chestnut might have antiplatelet effects. This has not been shown in humans.

Likelihood Possible Evidence D
Horse Chestnut full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Flavo-C, from the product label.

NF NutriPlex Formulas

See all NF NutriPlex Formulas products
Name
NutriPlex Formulas, Inc.
Street Address
3020 Carbon Pl #202
City
Boulder
State
CO
ZipCode
80308
Web Address
nutriplexformulas.com
Pharmacist Counseling Corner

Flavo-C by NF NutriPlex Formulas: Common Questions

Does Flavo-C by NF NutriPlex Formulas interact with any medications?
Yes. Based on its ingredients, Flavo-C has a known interaction with 1,018 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Flavo-C contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product actually improve night vision or help with age-related eye problems?
Bilberry in this product is rated possibly ineffective for night vision, and the evidence for age-related macular degeneration is insufficient. We don't have solid proof that Flavo-C improves either condition.
Is Flavo-C safe if I'm pregnant or breastfeeding?
Not entirely. Bilberry and acerola are likely safe in pregnancy, but echinacea is only possibly safe, and wild pansy and horse chestnut are unsafe in pregnancy and breastfeeding due to insufficient safety information. Talk with your doctor before using this product if you're pregnant or nursing.
What are the most common side effects?
Bilberry commonly causes dark-colored stools, gas, and gastrointestinal discomfort. Echinacea may cause stomach upset, nausea, diarrhea, rashes, or heartburn. Rare but serious reactions — including allergic reactions and hepatitis — have been reported with echinacea, particularly in people sensitive to ragweed.
Can I take this with my blood thinner medication?
No, not without checking first. Both bilberry and horse chestnut may increase bleeding risk with blood thinners or antiplatelet drugs. Talk to your doctor or pharmacist before combining this product with any blood thinner.
What is each ingredient supposed to do?
Bilberry supports eye health, acerola provides vitamin C, echinacea supports immune function, wild pansy is used for respiratory and skin issues, and horse chestnut supports circulation and venous health. However, reliable evidence that the product works for these purposes is limited.
Does this interact with caffeine or coffee?
Yes, potentially. Echinacea in this product can increase caffeine levels by about 30%, which could make you feel more jittery. If you're sensitive to caffeine, talk with your pharmacist before adding this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Flavo-C label
Go deeper

The Full Monographs Behind Flavo-C’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bilberry

Interacts with 275 drugs

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye health, circulation, and mild diarrhea. While...

Read the full Bilberry monograph → Herb & supplement monograph

Acerola

Interacts with 128 drugs

Acerola is a small tropical fruit prized for its very high natural vitamin C content, and it is mostly used as a food-based source of vitamin C and antioxidants. While vitamin C itself has w...

Read the full Acerola monograph → Herb & supplement monograph

Echinacea

Interacts with 816 drugs

Echinacea is a popular herb taken to help prevent or shorten the common cold, but study results are mixed and the overall benefit appears small at best. It is generally well tolerated for sh...

Read the full Echinacea monograph → Herb & supplement monograph

Heart's Ease

Heart's Ease (Viola tricolor) is a traditional European herb used mostly for skin problems and mild coughs. Modern human evidence for these uses is very limited, so it should be seen as a ge...

Read the full Heart's Ease monograph → Herb & supplement monograph

Horse Chestnut

Interacts with 122 drugs

Horse chestnut seed extract is most often used for chronic venous insufficiency, where standardized products may help reduce leg swelling, pain, and heaviness. Raw, unprocessed horse chestnu...

Read the full Horse Chestnut monograph →
Sources

Sources & How We Checked

Flavo-C's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 110 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bilberry 14 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Morazzoni P, Magistretti MJ. Activity of Myrtocyan, an anthosyanoside complex from Vaccinium myrtillus (VMA), on platelet aggregation and adhesiveness. Fitoterapia 1990;61:13-21.
  3. Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., and Jula, A. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr 2008;87(2):323-331. PubMed
  4. Hawrelak, J. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. J Altern Complement Med 2010;16(10):1065-1071. PubMed
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Echinacea 51 references
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Heart's Ease 4 references
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Horse Chestnut 21 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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