Flaxseed 450 mg Ingredients & Drug Interactions
by TerraVita Premium Collection
What is this page for?
First and foremost: checking Flaxseed 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Flaxseed 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for constipation and digestive health, high cholesterol, heart health.Based on those ingredients, 597 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Flaxseed. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Flaxseed 450 mg by TerraVita Premium Collection
Ask about any prescription or over-the-counter medication and we check it for interactions with Flaxseed 450 mg by TerraVita Premium Collection — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Flaxseed 450 mg by TerraVita Premium Collection
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: flaxseed at 450 mg per capsule. Flaxseed is a seed rich in lignans and alpha-linolenic acid, plant compounds that may affect cholesterol, blood sugar, and hormone balance.
The capsule itself is made from gelatin and water — these are inactive ingredients that hold the flaxseed together.
Does it work?
Moderate evidence
The evidence supports flaxseed as possibly effective for high cholesterol, high blood pressure, type 2 diabetes, breast pain (mastalgia), and constipation. These ratings mean the research is promising but not yet conclusive — it's not the strongest evidence, but it's encouraging enough that many people find it worth trying.
The strength of benefit varies by person and by condition.
How safe is it?
Well-documented data
Flaxseed is generally well tolerated when taken by mouth, but digestive side effects are common. Bloating, gas, diarrhea, and abdominal discomfort happen frequently, especially when you start or take larger doses.
Start with a small amount and drink plenty of water to ease into it. Doses over 45 grams per day are hard for most people to tolerate.
Severe allergic reactions are rare but can occur. Flaxseed supplement doses may have hormone-like effects, so avoid them unless your doctor approves — especially if you're pregnant, breastfeeding, or have a hormone-sensitive condition.
The safety data for supplement doses in pregnancy is not strong enough to say it's safe, and there isn't enough reliable information for breastfeeding either — talk with your doctor or pharmacist about whether it's right for you.
Meds to double-check
Moderate interaction found
Before you start, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (moderate severity — bleeding risk), blood pressure medications, diabetes drugs, antibiotics, or any estrogen-containing therapy like birth control or hormone replacement. Flaxseed's effects on blood clotting, pressure, glucose, and hormones can add to what your medicines are already doing.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Flaxseed is worth considering if you're looking to support cholesterol, blood sugar, or digestive health and don't take blood thinners or other medications that interact with it. If you're on any prescription — especially for blood pressure, diabetes, hormones, antibiotics, or bleeding prevention — check with your doctor or pharmacist before you start.
Expect some bloating and gas at first, and take it with plenty of water.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Flaxseed 450 mg, straight from the product label.
| Brand | TerraVita Premium Collection |
|---|---|
| Barcode (UPC) | 064435117672 |
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 21, 2023 |
| DSLD ID | 286574 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Flaxseed 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
A Dietary Supplement
Brand IP Statement(s)
Copyright 2004 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Suggested/Recommended/Usage/Directions
Directions Take 1 capsule, 3 times daily, with meals.
General Statements
TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.
Please recycle!
FDA Disclaimer Statement
Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Flaxseed 450 mg by TerraVita Premium Collection label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Flaxseed 450 mg by TerraVita Premium Collection
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
Flaxseed
Interacts with597 drugs
Flaxseed is a nutritious food rich in fiber, omega-3 fats (ALA), and plant compounds called lignans. It is most reliably helpful for constipation and...
Flaxseed monograph & interactionsOther (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.
Flaxseed 450 mg by TerraVita Premium Collection Drug Interactions
HelloPharmacist Interaction Report
Flaxseed 450 mg by TerraVita Premium Collection does interact with several medication types.
The most serious concern is with blood thinners and antiplatelet drugs (clot preventers) — flaxseed oil may thin your blood further, raising your bleeding risk.
Read the full breakdown — every affected drug type, severity by severity
Flaxseed also has documented moderate interactions with blood pressure medications, antibiotics, hormone therapies (including birth control and hormone replacement), and diabetes medications. With blood pressure drugs, flaxseed's ability to lower blood pressure could combine with your medicine and drop your pressure too far.
Antibiotics might alter how your body processes flaxseed's active compounds. Estrogens may see reduced effects from flaxseed's hormone-like lignans.
Diabetes medications carry a risk of low blood sugar (hypoglycemia) if flaxseed also lowers your glucose.
Altogether, these interactions span 597 individual medications. Use the search tool below to check your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Flaxseed 450 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Flaxseed 450 mg interact with 597 drugs. Click any drug to see the details.
1 of the 1 ingredient in Flaxseed 450 mg interact with drugs. Each result below shows which ingredient is responsible. Flaxseed
AbciximabReoPro
How Abciximab interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed + Albiglutide interactionAliskirenTekturna
How Aliskiren interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Ambrisentan interactionAmikacinAmikin, Arikayce
How Amikacin interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntibiotic Drugs Moderate
Interaction Summary
Theoretically, antibiotics might interfere with the metabolism of flaxseed constituents, which could potentially alter the effects of flaxseed.
Read the full Flaxseed + Amikacin interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Flaxseed 450 mg — through 1 ingredient. Tap an ingredient for the detail:
FlaxseedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed + Ammonium Chloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Flaxseed 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Flaxseed
Antibiotic Drugs
Theoretically, antibiotics might interfere with the metabolism of flaxseed constituents, which could potentially alter the effects of flaxseed.
Some potential benefits of flaxseed are thought to be due to its lignan content. Secoisolariciresinol diglucoside (SDG), a major lignan precursor, is found in high concentrations in flaxseed. SDG is converted by bacteria in the colon to the lignans enterolactone and enterodiol. Antibiotics alter the flora of the colon, which could theoretically alter the metabolism of flaxseed.
Anticoagulant/Antiplatelet Drugs
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Some clinical evidence suggests that the oil contained in flaxseed can decrease platelet aggregation.
Antidiabetes Drugs
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Some clinical research suggests that flaxseed can lower blood glucose levels.
Antihypertensive Drugs
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Clinical research shows that daily flaxseed consumption, especially for longer than 12 weeks, modestly reduces blood pressure.
Estrogens
Theoretically, taking flaxseed might decrease the effects of estrogens.
Flaxseed contains lignans with mild estrogenic and possible antiestrogenic effects. The lignans seem to compete with circulating endogenous estrogen and might reduce estrogen binding to estrogen receptors, resulting in an anti-estrogen effect. It is unclear if this effect transfers to exogenously administered estrogens.
Brand information
Manufacturer and brand details for Flaxseed 450 mg, from the product label.
TerraVita Premium Collection
See all TerraVita Premium Collection products- Name
- TerraVita Fine Whole Herbs
- City
- Brampton
- State
- Ontario
Flaxseed 450 mg by TerraVita Premium Collection: Common Questions
Does Flaxseed 450 mg by TerraVita Premium Collection interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will flaxseed interfere with my birth control?
What are the side effects?
Is it safe to take while pregnant?
Can I take this if I'm breastfeeding?
Does flaxseed really lower cholesterol?
How much should I take?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Flaxseed 450 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Flaxseed 450 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Flaxseed 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 37 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Flaxseed 37 references
- Kolonel LN, Nomura AM, Cooney RV. Dietary fat and prostate cancer: current status. J Natl Cancer Inst 1999;91:414-28. PubMed
- Ramon JM, Bou R, Romea S, et al. Dietary fat intake and prostate cancer risk: a case-control study in Spain. Cancer Causes Control 2000;11:679-85. PubMed
- Thompson LU, Rickard SE, Cheung F, et al. Variability in anticancer lignan levels in flaxseed. Nutr Cancer 1997;27:26-30. PubMed
- Nordstrom DC, Honkanen VE, Nasu Y, et al. Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. Rheumatol Int 1995;14:231-4. PubMed
- Cunnane SC, Ganguli S, Menard C, et al. High alpha-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. Br J Nutr 1993;69:443-53.
- Clark WF, Parbtani A, Huff MW, et al. Flaxseed: a potential treatment for lupus nephritis. Kidney Int 1995;48:475-80. PubMed
- Cunnane SC, Hamadeh MJ, Liede AC, et al. Nutritional attributes of traditional flaxseed in healthy young adults. Am J Clin Nutr 1995;61:62-8. PubMed
- De Stefani E, Deneo-Pellegrini H, Boffetta P, et al. Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. Cancer Epidemiol Biomarkers Prev 2000;9:335-8.
- Giovannucci E, Rimm EB, Colditz GA, et al. A prospective study of dietary fat and risk of prostate cancer. J Natl Cancer Inst 1993;85:1571-9. PubMed
- Clark WF, Kortas C, Heidenheim P, et al. Flaxseed in lupus nephritis: a two-year nonplacebo-controlled crossover study. J Am Coll Nutr 2001;20:143-8. PubMed
- Serraino M, Thompson LU. The effect of flaxseed supplementation on early risk markers for mammary carcinogenesis. Cancer Lett 1991;60:135-42. PubMed
- Rickard SE, Yuan YV, Thompson LU. Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside. Cancer Lett 2000;161:47-55. PubMed
- Mousavi Y, Adlercreutz H. Enterolactone and estradiol inhibit each other's proliferative effect on MCF-7 breast cancer cells in culture. J Steroid Biochem Mol Biol 1992;41:615-9.. PubMed
- Adlercreutz H, Fotsis T, Bannwart C, et al. Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets. J Steroid Biochem 1986;25:791-7.. PubMed
- Rose DP. Dietary fiber and breast cancer. Nutr Cancer 1990;13:1-8.. PubMed
- Lemay A, Dodin S, Kadri N, et al. Flaxseed dietary supplement versus hormone replacement therapy in hypercholesterolemic menopausal women. Obstet Gynecol 2002;100:495-504.. DOI
- Brooks JD, Ward WE, Lewis JE, et al. Supplementation with flaxseed alters estrogen metabolism in postmenopausal women to a greater extent than does supplementation with an equal amount of soy. Am J Clin Nutr 2004;79:318-25.. PubMed
- Laaksonen DE, Laukkanen JA, Niskanen L, et al. Serum linoleic and total polyunsaturated fatty acids in relation to prostate and other cancers: a population-based cohort study. Int J Cancer 2004;111:444-50.. PubMed
- Dodin S, Lemay A, Jacques H, et al. The effects of flaxseed dietary supplement on lipid profile, bone mineral density, and symptoms in menopausal women: a randomized, double-blind, wheat germ placebo-controlled clinical trial. J Clin Endocrinol Metab 2005 PubMed
- Brouwer IA, Katan MB, Zock PL. Dietary alpha-linolenic acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: a meta-analysis. J Nutr 2004;134:919-22.
- Demark-Wahnefried W, Polascik TJ, George SL, et al. Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery. Cancer Epidemiol Biomarkers Prev 2008;17:3577-87. PubMed
- Thompson LU, Chen JM, Li T, et al. Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer. Clin Cancer Res 2005;11:3828-35. PubMed
- Mani UV, Mani I, Biswas M, Kumar SN. An open-label study on the effect of flax seed powder (Linum usitatissimum) supplementation in the management of diabetes mellitus. J Diet Suppl 2011;8:257-65.
- Rhee Y, Brunt A. Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design. Nutr J 2011;10:44. PubMed
- Cornish SM, Chilibeck PD, Paus-Jennsen L, et al. A randomized controlled trial of the effects of flaxseed lignan complex on metabolic syndrome composite score and bone mineral in older adults. Appl Physiol Nutr Metab 2009;34:89-98. PubMed
- Cockerell KM, Watkins AS, Reeves LB, et al. Effects of linseeds on the symptoms of irritable bowel syndrome: a pilot randomised controlled trial. J Hum Nutr Diet 2012;25:435-43. PubMed
- Colli MC, Bracht A, Soares AA, et al. Evaluation of the efficacy of flaxseed meal and flaxseed extract in reducing menopausal symptoms. J Med Food 2012;15:840-5. PubMed
- Allman, M. A., Pena, M. M., and Pang, D. Supplementation with flaxseed oil versus sunflowerseed oil in healthy young men consuming a low fat diet: effects on platelet composition and function. Eur.J Clin.Nutr. 1995;49(3):169-178.
- Simbalista RL, Sauerbronn AV, Aldrighi JM, Areas JA. Consumption of a flaxseed-rich food is not more effective than a placebo in alleviating the climacteric symptoms of postmenopausal women. J Nutr 2010;140:293-7. PubMed
- Patade A, Devareddy L, Lucas EA, et al. Flaxseed reduces total and LDL cholesterol concentrations in Native American postmenopausal women. J Womens Health (Larchmt) 2008;17:355-66. PubMed
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