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Dietary supplement

Flow Secure + Ingredients & Drug Interactions

by Herbal Goodness

Flow Secure + label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Flow Secure + against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Flow Secure + is a dietary supplement by Herbal Goodness with 3 active ingredients. Its ingredients are commonly taken for heavy or prolonged menstrual bleeding, minor bleeding (nosebleeds, wounds), mild diuretic.Based on those ingredients, 407 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Shepherd's Purse Extract, Dong Quai extract, Yarrow Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Flow Secure + by Herbal Goodness

Ask about any prescription or over-the-counter medication and we check it for interactions with Flow Secure + by Herbal Goodness — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Flow Secure + by Herbal Goodness

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Extract Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Flow Secure + is a liquid supplement with 3 active ingredients. Shepherd's Purse extract and Yarrow extract have been used traditionally for women's health, while Dong Quai extract is an herbal ingredient with a long history in traditional medicine.

The product contains no inactive fillers or other ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: protection and comfort during menstrual cycle.
  • We looked for evidence on: Dysmenorrhea, Menorrhagia, Premenstrual syndrome (PMS), Menopausal symptoms, Postpartum complications, Menstrual bleeding — and 2 related terms.
  • The closest evidence on file: Shepherd's Purse is rated "Insufficient Reliable Evidence To Rate" for Postpartum complications (Natural Medicines).
  • Also on file: Shepherd's Purse is rated "Insufficient Reliable Evidence To Rate" for Menorrhagia.
  • Also on file: Yarrow is rated "Insufficient Reliable Evidence To Rate" for Dysmenorrhea.

The evidence on whether these ingredients work for their intended purposes isn't established in our data. Shepherd's Purse has been studied for postpartum complications and menorrhagia (heavy menstrual bleeding), but we hold insufficient reliable evidence to rate it either way.

Yarrow and Dong Quai have similar gaps — the evidence available isn't strong enough to say whether they're effective for the conditions they're traditionally used for. If you're considering this product for a specific health goal, talk with your pharmacist or doctor about what the science actually supports.

The evidence, ingredient by ingredient Shepherd's Purse Yarrow Dong Quai

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Shepherd's Purse and Yarrow both carry cautions: human safety data are limited when used short-term, and allergic reactions to yarrow can happen. Both are likely unsafe in pregnancy because they may affect the uterus, and neither has enough safety data to use while breastfeeding — so avoid them during both periods.

Dong Quai is also likely unsafe in pregnancy and best avoided while breastfeeding; additionally, it may increase bleeding risk and cause skin sensitivity to sunlight, so use with care if you take it. When used as directed in small amounts for short periods, Shepherd's Purse and Yarrow appear generally well tolerated, and Dong Quai is generally well tolerated orally — though burping and flatulence are the most common side effects reported with Dong Quai.

Side effects, ingredient by ingredient Shepherd's Purse Yarrow Dong Quai

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Shepherd's Purse, Yarrow, Dong Quai.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; lithium.
  • For scale: 407 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product with your pharmacist if you take warfarin (Coumadin) or other blood thinners — Dong Quai carries a Major interaction. Also flag any use of antiplatelet drugs, lithium, thyroid hormone replacement, or estrogens, which have Moderate interactions documented.

And mention any sedative medications, since Shepherd's Purse may add to their drowsy effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Flow Secure + may be worth considering if you're looking for traditional herbal support, but it's not for you if you're pregnant, breastfeeding, or taking warfarin, other blood thinners, lithium, thyroid medication, or estrogen therapy. Even if you don't take those drugs, check your full medication list with a pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Flow Secure +, straight from the product label.

Brand Herbal Goodness
Barcode (UPC) 810128950251
Net contents 12 Ounce(s); 354 mL
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 303500
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Girls: (All), Adult Female (18 - 50 Years), Seniors/Mature (>50 Years) - Women ONLY
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Flow Secure + by Herbal Goodness, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 mL
Maximum serving Sizes:
15 mL
Servings per container
23
UPC/BARCODE
810128950251
IngredientAmount% DV
Extract Blend0 NP--
Shepherd's Purse Extract0 NP--
Yarrow Extract0 NP--
Dong Quai extract0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Our exceptional Flow Secure liquid extract is meticulously crafted to provide superior protection and comfort during your menstrual cycle.

Quality We only use the best Made from the highest quality herbs, our products are tested to the highest standard by 3rd party certifiers.

Pre-menstrual support Concentrated 15x extra strength

General Statements

100% women-owned, 10% of profits support female education

Impact We do right by others We believe in business for social good and give 10% of profits to support the education of African girls. Sustainability We respect mother earth We believe in the environment and support our farmers through fairtrade practices. Women owned

Youtube herbalgoodness Facebook Herbal Goodness

Instagram herbalgoodnessco Twitter herbal_goodness

Seals/Symbols

Packaged in the USA

Storage

Warning: Store tightly closed in a cool dry place.

Precautions

Do not use if inner seal or tamper evident seal is broken.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Extract blend

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 tablespoon, 2 to 3 times a day with food. May be diluted with water or juice.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Flow Secure + by Herbal Goodness label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Flow Secure + label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Flow Secure + by Herbal Goodness

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size15 mL Dosage formLiquid Servings per container23 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Extract Blend

0 NP per serving
Interaction report

Flow Secure + by Herbal Goodness Drug Interactions

Want to check YOUR meds against Flow Secure +?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
407Drugs
2 Major 405 Moderate

Ingredients driving the most interactions

Shepherd's Purse Extract 264
Dong Quai extract 163
Yarrow Extract 1

Individual Drug Interactions

The ingredients in Flow Secure + interact with 407 drugs. Click any drug to see the details.

3 of the 3 ingredients in Flow Secure + interact with drugs. Each result below shows which ingredient is responsible. Shepherd's Purse Extract Dong Quai extract Yarrow Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Flow Secure + with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Shepherd's Purse Extract2 drug types · 264 drugs

Cns Depressants

Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, concomitant use may interfere with thyroid dysfunction therapy.

Likelihood Possible Evidence D
Shepherd's Purse Extract full monograph & interactions

Dong Quai extract3 drug types · 163 drugs

Warfarin (Coumadin)

Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.

Likelihood Possible Evidence D
Estrogens

Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.

Likelihood Possible Evidence D
Dong Quai extract full monograph & interactions

Yarrow Extract1 drug type · 1 drug

Lithium

Theoretically, taking yarrow with lithium might increase the levels and adverse effects of lithium.
Animal research shows that yarrow has diuretic activity. Theoretically, due to these potential diuretic effects, yarrow might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Yarrow Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Flow Secure +, from the product label.

Herbal Goodness

See all Herbal Goodness products
Name
Herbal Goodness
Street Address
2150 S. Central Expressway, Suite 200
City
McKinney
State
TX
ZipCode
75070
Phone Number
800-820-4829
Web Address
herbalgoodnessco.com
Pharmacist Counseling Corner

Flow Secure + by Herbal Goodness: Common Questions

Does Flow Secure + by Herbal Goodness interact with any medications?
Yes. Based on its ingredients, Flow Secure + has a known interaction with 407 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Flow Secure + contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Flow Secure + if I'm pregnant or breastfeeding?
No. Both Shepherd's Purse and Yarrow are likely unsafe in pregnancy because they may stimulate the uterus, and there isn't enough safety data to use either while breastfeeding. Dong Quai is also best avoided during both pregnancy and breastfeeding. Talk with your doctor or pharmacist about what's safe for you.
What are the most common side effects?
Shepherd's Purse and Yarrow are generally well tolerated when used short-term in small amounts. Dong Quai is also generally well tolerated orally, with burping and flatulence being the most common side effects. Yarrow applied to skin can cause allergic reactions like dermatitis or rash.
Does this product actually work for its intended use?
We don't have strong enough evidence in our data to say whether Shepherd's Purse, Yarrow, or Dong Quai work for the conditions they're traditionally used for. If you're considering it for a specific reason, ask your pharmacist what the research actually shows.
Is it safe to use with other medications?
That depends on which medications you take. The biggest concern is if you're on warfarin or other blood thinners — Dong Quai increases your bleeding risk. You should also check with a pharmacist if you take lithium, thyroid medication, estrogens, or sedative drugs before adding this product.
Can Flow Secure + cause sun sensitivity?
Yes, Dong Quai may increase your skin's sensitivity to sunlight. If you use this product, be extra careful with sun exposure — use sunscreen and protective clothing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Flow Secure + is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Flow Secure + label
Go deeper

The Full Monographs Behind Flow Secure +’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Shepherd's Purse

Interacts with 264 drugs

Shepherd's purse is a traditional herb most often used to help slow heavy menstrual bleeding and other minor bleeding, but solid human research is very limited. Because it may affect blood c...

Read the full Shepherd's Purse monograph → Herb & supplement monograph

Yarrow

Interacts with 1 drug

Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used...

Read the full Yarrow monograph → Herb & supplement monograph

Dong Quai

Interacts with 163 drugs

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scientific evidence that it works for these use...

Read the full Dong Quai monograph →
Sources

Sources & How We Checked

Flow Secure +'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 31 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Shepherd's Purse 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Naafe M, Kariman N, Keshavarz Z, et al. Effect of hydroalcoholic extracts of Capsella bursa-pastoris on heavy menstrual bleeding: A randomized clinical trial. J Altern Complement Med. 2018;24(7):694-700. PubMed
  4. Ghalandari S, Kariman N, Sheikhan Z, et al. Effect of hydroalcoholic extract of Capsella bursa pastoris on early postpartum hemorrhage: A clinical trial study. J Altern Complement Med. 2017;23(10):794-799.

See these in context on the Shepherd's Purse monograph →

Yarrow 8 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
  3. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
  4. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
  5. Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.
  6. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
  7. de Souza P, Crestani S, da Silva Rde C, et al. Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae). J Ethnopharmacol. 2013 Aug 26;149(1):157-61. PubMed
  8. Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani M. Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. Eur J Oncol Nurs. 2015;19(3):207- PubMed

See these in context on the Yarrow monograph →

Dong Quai 19 references
  1. Hirata JD, Swiersz LM, Zell B, et al. Does dong quai have estrogenic effects in postmenopausal women? A double-blind, placebo-controlled trial. Fertil Steril 1997;68:981-6. PubMed
  2. Page RL II, Lawrence JD. Potentiation of warfarin by dong quai. Pharmacotherapy 1999;19:870-6. PubMed
  3. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  4. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  5. Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
  6. Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause 2002;9:145-50. PubMed
  7. Shi M, Chang L, He G. [Stimulating action of Carthamus tinctorius L., Angelica sinensis (Oliv.) Diels and Leonurus sibiricus L. on the uterus]. Zhongguo Zhong Yao Za Zhi 1995;20:173-5, 192.
  8. Hoult JR, Paya M. Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential. Gen Pharmacol 1996;27:713-22.. PubMed
  9. Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
  10. Chang CJ, Chiu JH, Tseng LM, et al. Modulation of HER2 expression by ferulic acid on human breast cancer MCF7 cells. Eur J Clin Invest 2006;36:588-96. PubMed
  11. Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
  12. Lau CBS, Ho TCY, Chan TWL, Kim SCF. Use of dong quai (Angelica sinensis) to treat peri- and postmenopausal symptoms in women with breast cancer: is it appropriate? Menopause 2005;12:734-40.
  13. Ellis GR, Stephens MR. Untitled (photograph and a brief case report). BMJ 1999;319:650.
  14. Nambiar, S., Schwartz, R. H., and Constantino, A. Hypertension in mother and baby linked to ingestion of Chinese herbal medicine. West J Med 1999;171(3):152.
  15. Lee, S. K., Cho, H. K., Cho, S. H., Kim, S. S., Nahm, D. H., and Park, H. S. Occupational asthma and rhinitis caused by multiple herbal agents in a pharmacist. Ann.Allergy Asthma Immunol. 2001;86(4):469-474. PubMed
  16. Xu, J. and Li, G. [Observation on short-term effects of Angelica injection on chronic obstructive pulmonary disease patients with pulmonary hypertension]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000;20(3):187-189.
  17. Scott, G. N. and Elmer, G. W. Update on natural product--drug interactions. Am J Health Syst.Pharm 2-15-2002;59(4):339-347. PubMed
  18. Circosta, C., Pasquale, R. D., Palumbo, D. R., Samperi, S., and Occhiuto, F. Estrogenic activity of standardized extract of Angelica sinensis. Phytother.Res. 2006;20(8):665-669.
  19. Fung FY, Wong WH, Ang SK, et al. A randomized, double-blind, placebo- controlled study on the anti-haemostatic effects of Curcuma longa, Angelica sinensis and Panax ginseng. Phytomedicine. 2017;32:88-96. PubMed

See these in context on the Dong Quai monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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